Dmac008438.2
Basic Information
- Insect
- Drosophila maculinotata
- Gene Symbol
- -
- Assembly
- GCA_035045305.1
- Location
- JAWNPD010000387.1:10771263-10776586[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 14 0.0015 0.099 13.2 0.5 2 23 154 175 153 175 0.97 2 14 0.00014 0.0097 16.4 1.3 1 23 401 423 401 423 0.98 3 14 3.6 2.4e+02 2.6 0.8 1 23 429 452 429 452 0.92 4 14 3.5 2.4e+02 2.6 0.5 1 23 479 502 479 502 0.91 5 14 0.0013 0.086 13.4 1.9 3 23 765 785 764 785 0.92 6 14 0.05 3.4 8.4 1.4 1 23 791 814 791 814 0.98 7 14 0.13 8.7 7.1 2.1 2 23 851 872 850 873 0.92 8 14 0.0093 0.63 10.7 0.6 1 23 892 915 892 915 0.97 9 14 0.021 1.4 9.6 0.4 1 23 1130 1153 1130 1153 0.90 10 14 0.018 1.2 9.8 5.9 1 23 1166 1188 1166 1188 0.98 11 14 6.4e-06 0.00044 20.6 0.8 2 23 1194 1216 1193 1216 0.96 12 14 0.00049 0.034 14.7 2.9 2 23 1223 1247 1222 1247 0.88 13 14 0.058 4 8.2 0.7 1 23 1252 1274 1252 1274 0.97 14 14 0.089 6.1 7.6 2.2 1 23 1280 1303 1280 1303 0.96
Sequence Information
- Coding Sequence
- ATGGCGAACAAGCGACTGAAAATAGAAAGCAGGGAAGTGAACTACAAATTTACGTGTCGCTGTTGCTTAAAATCCGAGGCGGAATTCTTCCCATTGGATTCGCTGATCGAAGTTGGACAAGGATGCGACAGTAACCAATACCCCACCCCCTCCACCTCTACCTCCGCCACATCGACAAAAATGTCGCTCATGCGTTTATTACTTTTTTGCTTGCGCACCGAAAATCCGCCCGAACTGCCGCAATATATTTGCGTTGAGTGCAGCAAAAGTCTACAAATTGCCTACTATTTCATCCAGAATGGACTCCGTGCCCATGAGATCTTGTGTCGTAAGCTAAAGCCCAAATCCCGTTACAATGGACTACAGCGTTCGGCGTTCCCCGAGAAATATGAGCAAGTTGGGGCGGCGCAGGAGCGGAACAGGGCTCAAAAGAAGCCAGCGAAGGGCGAAGTGCGACAGGAATGCAAAATATGCGGCAAGATTATCTACAATCGATTAGAGTTCCGGCAACACTTGCGCATGCACACAGATTCTGCGCTTCATCAGTGCAAATTGTGTAAGTTTGGGACGCTGAAGCATCGCCAGCTGCTGGAGCATTACAGTAAGGTGCATGCTTTGACAGCCGCCGAAATTGAGCATCAGcttaaaattcgaaaatccATTGTGGCGGCTGCCAGCGCAATGACAACAGCGGCTACTTCTACCACAGAAACAGAACCTGAGGATGATAGTCAAGTGAAGGTGTGCACACTGGAGGACATGGAGCTGCTAATACCCACAGTGTTGACGCCTGAGGATTTCACGCGTCCGCAACTGGATAGCGTGATGTTGCGTGATATTGagcaacaatttgcaaactCATTGCCTAAAGCCGATTCCTCTAGCATACCATCTGAACCGACGATAGCTGGAGGATCTGGCGCTAATGTTAGCGTTGGTGCCGAGTTTTTGATCATGCCCGATGGCTCGCTGCAGAAAGTGAATGACGGTGGCGTGGTTTTCGAGTATATTGATGATAGCAAAAATGGCAATAGCACAACCAATATGACGTTGCAGAGTCTGTTGAGTGACTCCAAAACAGATTTGTCACAGAATGCCATGAATATTGATCTGAGCCATATGATTGTCGATAATGTCCTACCACAAATCAATGTTAAACCCAAGCTGCGGCCAGGGCCGGCATCAATTGGCGCCTTGAAACATAAGTGCAAACTGTGCCCCAAAGCATTTCCCACGGTGGCACGCCTGAAATCTCATCAACTAACGCATAGCCATTTGCCCAAATTCTTTTGCGATCAGTGCTCCTACTATTCGCTGCGCAGCGCCGATCTCATCCAGCATTATACGACCGAGCACAACGTCAGCGTAAGCGATAGTAAAGCCAGCCAGGCGGATAAGACTCTAATGCCGCAGGTGGCGGATCGAAATCTCATCTTTTCCTGCGATATGTGTCTGTTTGAGACGTCGAGCGGCGGTCAGTTGCGCTTACACTACAGCGATAAGCATCTGATGGTGCCCAGTGAGATACAGCTACGTCCCAGCTGGATCAGGGAAAAGGACGGCCGCACGAAACTAAATAGCGGCTCCACTCAGCCAGATATTCCGCTTGGCATTACATATCCTCCCATGTCTTCTGCAGAAACAATAACCACTACTATCTtggagcagcagaagcagcaacatccgcagcagccgcaggcTACAACCACAACGGTTCTGACAGCAGACGGAGACATCAATGTTGTTGTGGATGCCAGCACATTGTTCTTTGCACCAGCTGCAGACAGTATTACAagtggaacaacaacaacggcaacattAACAGAATCTAACACATTTGCATTATTCTCCGAGCAATCTTTTGCCAATAGCCTGTCaacaccaaaaaaatccaaaaaaaccACAACGAGGGCTAGCGTTGCGCCGTCTGCGACAGAGATAACAACAAACCCCAATAGTAGCTTATTTGGCGATATGCAGGAATTTATAGATAACACCGATGTAGCAGCTATATGCACCATACCCGCCGATGATATGCCCGTTGTTGATGGTGATGATATCGTTATTGATAACAATAACATCAGTCTGGATTTTGATGCAGAAAATCTATTTGAGGAGTTTGAAGACGCTGAAGTGGGTGAAGATGACGATGAGGACGAGGATGATGCCGAAAATGATGATGAGAATGATAACAATGATGCAGCAGCCGATCAGAATCTATTGCTCACCagcgacgatgacgatgtGGACGACTTTGATGACGAACAATCGAAGCATCTACAGAAaccatattgtatatattgcaacaaaaagtttaccagtcaatacaagtttgaGAATCATATGTTTGTACATCGCGGTTTGGCACCGTATCGCTGTGAATTGTGCACGAATCTGTACAATATGAAACGTCTGCTCATACGACACTACAAGACGGTGCACAAGCGAATGCCCACTCGGGACATGGTGCAGGCCAAGGGCGACAAGGTATCCGTGCCGCGTACAACCATCGAAaagattaatatttatgctgCCAAAACTCCCATGCTGATGTGCGCCAAGTGTCCCTTTGAATGTGAGCAGGAGAGTGATATGCGCAAGCATCTCAATGCGCATCATGGCATCAACGATGGCGTGCATGCCAACGAGGTGTTCATCATTCGCAAACTGCCCTATGAGTGTCCACGCTGCATTCGTTCATTTGCTGCCAAGCGAACGCTGAATCAGCATCTGCAGCGAAGCCATTTAGTGGATACGATCATTGAGATGCATGCGCCTCAATTGACAACTGGTTCAGCGTCAACCACAACCACATCGACGGCAACAACCACATTGCCGAGCAATGCTAGCGatgttaataaaacaaaaacacgtGAGGAGGCCAATGTCGAAggtgatggtgatggcgatggcgatggtaAATGCGCAGAGCAAGCGGTAGACAAGGACACCGGATTAGAAACGGAAAATGCAGATACCGATATAAAAACCGCAGTAACAATACAAGAAATAAAAGCACAATCAACAACAGCTACTACAGCAATCCATGAAATTAAGGCAGAAGTAAAAACGGATTTAacagttgcaactgcaacaacaattgaagctgaagctgccgcagcaacaacactaacactaacgaCAACCGAATtttcaccaacaacaaacgcaGGCACAACGCTCTTTCCAACGCCCACGCCATTTGACTTTGATCTTGACTTTATGGGCGACGAAAGCCATTCCACGCCCCTTAAGATCAACAACGATACCTTCGACGATGCGCCCAGTCCCAGTCTACTGCTGAATGGCAGCGATAAGTTGCTGACTGCCGCGTTGGAGCCATCGCCCGTTAAGGATTTACGCTCCTGCCTGCCGCGTACACCCATATTTGTGTGCAAGCAATGTAACCAGACCTTCGATGAGCTCGGCAAGCTATTGCAGCACGAGTTGGATCAACATTCCAGCGGGTCTGTATCGTCGACCAGCAATTACCAGCATCAGTGCAAGATCTGTCACAGCACTTATCGCACTGTGACGCTACTCAATTATCATATGAAGCAACATACGCCGGTCAAAATACCGTGCAAACAGTGCCCCAAGAAGTTTGACCACAGTGCGGACTTGGAGAAGCATATGCAGTCGGAGCATTGCGCCAATATGCCCCTCACATGCGGCATAGATGGTTGCAAGAAGGCGTTCAGTTACAAGCATCATCTGAAACGTCATCAGACAGCCTCGCATACGCCGGTTCAGTATATTTGTCCAGAGTGCGGCTGCGATATGCAGACCAGTCTGCAGCTGAGGAGTCACATGTCCTTACACCGAAGCACACACTCGTACAAGTGTCCCAGGTGTGTTCGCACCTATCTACGTCGTAATTCTTTCCGTCGGCATGCGCTACGTTCGCACAAATGGGATTTGACGGAGACCGAAATTGACAAAATTTGTAGCAAAACTGATACACCGGCATCAATCCAAGCACTCAGGCGAAGATCGGTGAGGACTGAGAGTGTTCAGTCTGATTAG
- Protein Sequence
- MANKRLKIESREVNYKFTCRCCLKSEAEFFPLDSLIEVGQGCDSNQYPTPSTSTSATSTKMSLMRLLLFCLRTENPPELPQYICVECSKSLQIAYYFIQNGLRAHEILCRKLKPKSRYNGLQRSAFPEKYEQVGAAQERNRAQKKPAKGEVRQECKICGKIIYNRLEFRQHLRMHTDSALHQCKLCKFGTLKHRQLLEHYSKVHALTAAEIEHQLKIRKSIVAAASAMTTAATSTTETEPEDDSQVKVCTLEDMELLIPTVLTPEDFTRPQLDSVMLRDIEQQFANSLPKADSSSIPSEPTIAGGSGANVSVGAEFLIMPDGSLQKVNDGGVVFEYIDDSKNGNSTTNMTLQSLLSDSKTDLSQNAMNIDLSHMIVDNVLPQINVKPKLRPGPASIGALKHKCKLCPKAFPTVARLKSHQLTHSHLPKFFCDQCSYYSLRSADLIQHYTTEHNVSVSDSKASQADKTLMPQVADRNLIFSCDMCLFETSSGGQLRLHYSDKHLMVPSEIQLRPSWIREKDGRTKLNSGSTQPDIPLGITYPPMSSAETITTTILEQQKQQHPQQPQATTTTVLTADGDINVVVDASTLFFAPAADSITSGTTTTATLTESNTFALFSEQSFANSLSTPKKSKKTTTRASVAPSATEITTNPNSSLFGDMQEFIDNTDVAAICTIPADDMPVVDGDDIVIDNNNISLDFDAENLFEEFEDAEVGEDDDEDEDDAENDDENDNNDAAADQNLLLTSDDDDVDDFDDEQSKHLQKPYCIYCNKKFTSQYKFENHMFVHRGLAPYRCELCTNLYNMKRLLIRHYKTVHKRMPTRDMVQAKGDKVSVPRTTIEKINIYAAKTPMLMCAKCPFECEQESDMRKHLNAHHGINDGVHANEVFIIRKLPYECPRCIRSFAAKRTLNQHLQRSHLVDTIIEMHAPQLTTGSASTTTTSTATTTLPSNASDVNKTKTREEANVEGDGDGDGDGKCAEQAVDKDTGLETENADTDIKTAVTIQEIKAQSTTATTAIHEIKAEVKTDLTVATATTIEAEAAAATTLTLTTTEFSPTTNAGTTLFPTPTPFDFDLDFMGDESHSTPLKINNDTFDDAPSPSLLLNGSDKLLTAALEPSPVKDLRSCLPRTPIFVCKQCNQTFDELGKLLQHELDQHSSGSVSSTSNYQHQCKICHSTYRTVTLLNYHMKQHTPVKIPCKQCPKKFDHSADLEKHMQSEHCANMPLTCGIDGCKKAFSYKHHLKRHQTASHTPVQYICPECGCDMQTSLQLRSHMSLHRSTHSYKCPRCVRTYLRRNSFRRHALRSHKWDLTETEIDKICSKTDTPASIQALRRRSVRTESVQSD
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- -
- 90% Identity
- -
- 80% Identity
- -