Basic Information

Insect: Drosophila maculinotata
Gene Symbol: GFI1
Assembly: GCA_035045305.1
Location: JAWNPD010000452.1:564897-582213[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 6 0.00021 0.014 15.9 3.6 1 23 507 530 507 531 0.96

2 6 0.00031 0.021 15.3 0.5 1 23 536 558 536 558 0.97

3 6 3.6e-07 2.5e-05 24.6 1.9 1 23 564 586 564 586 0.98

4 6 1.8e-05 0.0012 19.2 4.2 1 23 592 614 592 614 0.97

5 6 2.2e-07 1.5e-05 25.2 2.5 1 23 620 642 620 642 0.98

6 6 4.5e-05 0.003 18.0 5.0 1 23 648 671 648 671 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	6	0.00021	0.014	15.9	3.6	1	23	507	530	507	531	0.96
2	6	0.00031	0.021	15.3	0.5	1	23	536	558	536	558	0.97
3	6	3.6e-07	2.5e-05	24.6	1.9	1	23	564	586	564	586	0.98
4	6	1.8e-05	0.0012	19.2	4.2	1	23	592	614	592	614	0.97
5	6	2.2e-07	1.5e-05	25.2	2.5	1	23	620	642	620	642	0.98
6	6	4.5e-05	0.003	18.0	5.0	1	23	648	671	648	671	0.97

Sequence Information

Coding Sequence: ATGAACGTTGGCAAGATGCAAGCGCCtgggcagcatcagcatctgcTGCATCCGGCTGCTTCCGCTGCACCGCCGCCGACGCAACAGCATCATTTGCCCATCGATTACAGTTTGGGCAACTTTAAGCCAGCCATTGCTGCCGATTTTCCCGGCGGCCCCTTCGTCGCCAgcccccagcagcagcagtcctcATCCTCCACGTCGCCCTCAATTGCCACGTCAGTCGCTTCGCTGCAGGTGCGAGATCTCAGCACCTTGACCACAATGGCCGCGATACCCTCGCCCACCCAGCTACTCCATCAGCGCATGCAACCGGCCCAAATCACTGTGGGtgcacatcagcaacatcagcaacaccagcaacaccaacaacatcagcaacatcagcaaatgCCGCCGGCGGCAACATCGCCACATGATTACGCGCCCATGTCCGCCTTCAAGGCGGTGCTGCCCAAGAAGCGAAATACCGACGATACGTCGCACCCCTTCAGCATAAGCAGATTGGTCAAGACTGAACACCTGACGGCAATTGTTGCCGCTGCGGCATTGAAGCCGCCGCCGTCGCTGCCGGCGCACAGTGTCGCTTTGGCggaggacaacaacaactccatCTCGATGCTGAGCAAAaaccatcaacagcagcagccatcccACATTCCACGACCCAAGCTGCTGCCTTATCTGAGCGCCAGCGAGCTGCTGCGTCAGTCGCGCTCCCGATCGAGATCCCGTTCGCGCAGCGCATCGCACTGCTCCTCACAGATTGACATGGACGATGCGGATAGCAGTCACGAGCGGTATTCCCGGCATTCGCGTCTGTCGCTGCACTCACGCTCCCGCTCCCGGTCCCGCTCCAGATCCCGATCGCATTCGAGCAGCTCGTCGGTGGAACTGGAGGTGGACTCGCCGCCGGGCAGTCCCAGCATTAGTTCGCCCAGTGCCGCCTCCGTGTCCGCCTCCGAGCTGCTAATCAcggccaacagcaacattagcGCCAAGAAATCGGATCTCTTCTCCGTCTCCGCGCTCCTGCGTCGCGATGAGCCATCAACACGACGTATTCGCAGTCCACCGCTTGGTTTGGTCGGAGTTTCGAATTCAGCGCTGGCGCTGCCCACCAATCCTCTCGAGGTCATGCGGCAGAGCTACCCGCCCAACTACGAAGCGGCCATGTTCCAGCGACCCATCTTCTCCCCAGCGCTGCCCTTCTTTGCCGCCATTGCCTTTCATCagggacagcagcagcaacaacaacagcaatccgGTCTGGTCGCAAGCTACCATCCGGACTCGCAGGAAAATCTCTTCCGGCTGCGCAGCCTGATGGTGCCACTACAGTCCGCTGGCCAGAATGGCTCCACAGCGgcagctgcggcggcggcagcagcggcggccgTTGGTGTGGGCGTTGGTGTGCCACCCGGTGGCGGGCATTTGGGTCTGCCGCATCCGCCGCATCTGCACTTCCATCACATGGCGGCCAAGTGGCCGGGCCTGCATCAATTTAGCGACCTGTACTCGTGCATGAAGTGCGAGAAAATGTTCTCCACGCCGCACGGACTCGAGGTGCACTCGCGCCGCACCCACCACGGCAAGAAGCCCTACGCCTGCGAGCTGTGCAACAAGACCTTCGGCCATGAGGTCAGCCTCAGCCAGCACAGGGCGGTGCACAACGTGGAAAAGGTCTTTGAGTGCAAGCAGTGCGGCAAACGCTTCAAGCGCTCCAGCACCCTCTCCACCCATCTGCTCATCCACAGCGACACGAGGCCTTATCCCTGCAGCTACTGCGGCAAGCGATTCCATCAGAAGAGTGATATGAAGAAGCACACCTACATTCACACCGGTGAGAAACCGCACAAGTGTCAGGTGTGTGGCAAGGCATTCAGTCAGAGCTCAAACCTGATAACGCACTCCCGCAAGCACACCGGCTACAAGCCCTTCTCCTGCAAGCTCTGCCACAAGTCCTTCCAGCGCAAAGTGGATCTGCGGCGGCACAAGGAGACACAGCACACAGATCTGCGCGTGCAACTGGGCAAGGTGGACTTTATGTCTGCCGCAGcggccgctgcagctgctgccgagCTGAGTGCAGGTCCTGGAGGTCCTGGAGGCATGGGACTGTCCGCTGGCGGTGCAGCGCCACAGCCTGGAGGAGCAGTGTCCACGAACTCAATGAATTGCCAAAAGGTATCACTGCTGgcataa
Protein Sequence: MNVGKMQAPGQHQHLLHPAASAAPPPTQQHHLPIDYSLGNFKPAIAADFPGGPFVASPQQQQSSSSTSPSIATSVASLQVRDLSTLTTMAAIPSPTQLLHQRMQPAQITVGAHQQHQQHQQHQQHQQHQQMPPAATSPHDYAPMSAFKAVLPKKRNTDDTSHPFSISRLVKTEHLTAIVAAAALKPPPSLPAHSVALAEDNNNSISMLSKNHQQQQPSHIPRPKLLPYLSASELLRQSRSRSRSRSRSASHCSSQIDMDDADSSHERYSRHSRLSLHSRSRSRSRSRSRSHSSSSSVELEVDSPPGSPSISSPSAASVSASELLITANSNISAKKSDLFSVSALLRRDEPSTRRIRSPPLGLVGVSNSALALPTNPLEVMRQSYPPNYEAAMFQRPIFSPALPFFAAIAFHQGQQQQQQQQSGLVASYHPDSQENLFRLRSLMVPLQSAGQNGSTAAAAAAAAAAAVGVGVGVPPGGGHLGLPHPPHLHFHHMAAKWPGLHQFSDLYSCMKCEKMFSTPHGLEVHSRRTHHGKKPYACELCNKTFGHEVSLSQHRAVHNVEKVFECKQCGKRFKRSSTLSTHLLIHSDTRPYPCSYCGKRFHQKSDMKKHTYIHTGEKPHKCQVCGKAFSQSSNLITHSRKHTGYKPFSCKLCHKSFQRKVDLRRHKETQHTDLRVQLGKVDFMSAAAAAAAAAELSAGPGGPGGMGLSAGGAAPQPGGAVSTNSMNCQKVSLLA

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00586160;
90% Identity: iTF_01322121;
80% Identity: -