Dmac002310.1
Basic Information
- Insect
- Drosophila maculinotata
- Gene Symbol
- ken1
- Assembly
- GCA_035045305.1
- Location
- JAWNPD010000319.1:469071-471290[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 12 0.0047 0.32 11.6 5.0 2 23 205 226 204 226 0.96 2 12 0.023 1.6 9.4 0.1 1 21 232 254 232 257 0.89 3 12 0.14 9.8 6.9 0.1 3 23 266 289 264 289 0.93 4 12 0.0021 0.15 12.7 1.8 2 23 302 323 301 323 0.96 5 12 1.1e-05 0.00076 19.9 0.6 1 23 330 352 330 352 0.98 6 12 0.0067 0.45 11.1 0.1 1 23 358 380 358 380 0.98 7 12 0.036 2.4 8.8 2.1 1 23 386 409 386 409 0.97 8 12 0.0084 0.57 10.8 3.9 1 23 415 437 415 437 0.96 9 12 0.001 0.069 13.7 2.9 2 23 444 465 443 465 0.96 10 12 9.7e-05 0.0066 16.9 1.6 1 23 568 591 568 591 0.95 11 12 0.013 0.87 10.2 0.7 1 19 597 615 597 619 0.95 12 12 3.5e-05 0.0024 18.3 1.1 3 23 627 647 626 647 0.99
Sequence Information
- Coding Sequence
- ATGAGCACAGTGTCACCGTACTCCGTTTATTCAATATGTCGAGTTTGCCTGGAATTTTTGGAGACCAGTATAGTATATGATCTGTTTCTATTGCCAGATCTCGCCAAGAAATTCACAGTTTGCACATCTTTGCTCCTGGATGCCCAGGATGGCTATCCCAGGCACCTCTGTGCTAGCTGTTACGCCCGACTGAATGACCTACATGAGTTCCAGCAGCTCTGTGTGGCGTCGGTGCAGAGACTCAAGCAAATGGTTGCCAACAGGATCATCCCCAATGTGAACCGGATTGAGCTATTTGCCAGCAATGAGGATGAACTGCTGGCCAAGGATGAGCAGCCGGGCAGTGATTATGATCCACTGTCAAGTCACAAACAGGAGCTGATCAATAACGAAGAGGAGGTCTTCAAGTTGCTCGAGGATGTCGACAAGGATGCCAAAGAGGTGACACTTTTTACTGACTCCTCATCGGATTGCAGCCTCAGCGATGATGATGTGCCTCTGGCACAGCGCCTGCTAAATCAAAACAGCGATACGGATTCCGAAAAGTGTCTCCAAACGCAGGCAAAGCGTAAGCGGATTCCCGCATCAGAGCGTCATCTGCATCGCATTATCAGCTGCCAGATATGCCATCAGAAGTTCAAGAAACAAGTCAACTACGATGAGCACATGAAGCACCATAACGAATTGCTGCCGTTTCAGTGTCAGGTGGTAAGCTGCCGTAAAGGCTTCACCACAGCGGCTGCACTGCGTCTGCATGGCGATTATGCGCACACAAAGAGTGCCGCTGAAATACCCTGCACAGTTGCCGGGTGCAAGCTTCTATTCCCACGCATGCGACTGCTCACCATTCACCTGAAGAAGGTGCACAATATGTCGCGGATCAGTGTGCCGCGCACGGAGCAGCCGTGCAGCGAGTGTGGCATGCAATTCCGTTGCCCAGTGTCGCTTAAGAAGCATATGTACAAGCATACGGGAGAGCAGCTGCCGTATCCTTGTAATATATGCGGCAAGGGTTTCCACATAAACAGCGCCCTCAAGAATCATCTGCTGCGACATGCGGGCATCAAGAACTATGTGTGTCCCTACTGTGGTGTGGGAAAAACCACGCGGCAGGAGTGGAGTAAGCACATCCTGACCCACACGCAGGAGAAGATGTTCAAGTGCCAGATCTGTGAGCATGCCACACACACCAAGCGAGCGCTGGATAATCACGTAAAGATCGTCCACGAAAAGGTCAGAAATTATGCGTGCCAGTACTGCGGGAAGACCTTTGGCAAGTCGCACGCCTGCAAAATCCACGAGATGACGCACACCGGCGAGAAGCGATGCGAATGCAAGGTCTGCGGCAAGAAGTTCCTCTACACGGAGAGCTTGACCAAGCATTTAAAGATACACGAGAAGAGTGTGGAACGTGCCATTGAAACGTATCGCCAGCGGCAGGTCGAACTCGGTGGATCAGGTGCAGCTGCTGAACAGCTGCCAAGTAGAAACACTGATTGCCAGTTGGAAAACGAGGGCAATGCAGCCGATCAGCTTTTGAAGGTGTGTGCTGAGTCTGTGGCCACCATACCGCGAGATCCGCGACGTGTGGAACGTGTGGACATCGCTCAGCTGGCTGGCACCGTTGTCAATCCCATATCCGCCGTTTTGGTGCCGTCAAAAGCGCCAGCGCCTCTGAACTTTGTACAAAAGGAGGGCATGCACTTTTGCCCGGGCTGTAATCAGGGTTTTAACAATTTGGGTAACATGAAGCGACACTACAAGAGCGTCCACGAGAAAGTCAAGGACTTTGAGTGTCGCTTCTGCGCACGTCGCTTTGCCAACTCGCAATCCCTCAAGCAGCACGAATGGATTCACACGGGCGAAAAGCCGCATGGATGCAAGACTTGTGGCACCCACTTCCGTCAGGAGGCGGCTTTAATACGCCACCAGAAGGTTCACGACCAAAAACCACCGAAGCCAACGAAACCGCCTAAGCAAATAACTGAAAGGTTTCGGCAAAAGGAGCTGCAGAAATGTGAGAAGCGGCGCAAAGTTGAATCGTTGCGTCTGAAAATCGCCGATGCAGCTAAAGAGGAGCTCCAGGAACTGGCCAAGCAGCGTGTCCTAGAAAAGCAGCACAATACCTACGAACAGTATCAGGCGGCAGCCGCAGCGGCTGCTGAAAGGACGACGACGCATCCACCAAACGACCCCGAGAGTAAATTATTATCTATTTGA
- Protein Sequence
- MSTVSPYSVYSICRVCLEFLETSIVYDLFLLPDLAKKFTVCTSLLLDAQDGYPRHLCASCYARLNDLHEFQQLCVASVQRLKQMVANRIIPNVNRIELFASNEDELLAKDEQPGSDYDPLSSHKQELINNEEEVFKLLEDVDKDAKEVTLFTDSSSDCSLSDDDVPLAQRLLNQNSDTDSEKCLQTQAKRKRIPASERHLHRIISCQICHQKFKKQVNYDEHMKHHNELLPFQCQVVSCRKGFTTAAALRLHGDYAHTKSAAEIPCTVAGCKLLFPRMRLLTIHLKKVHNMSRISVPRTEQPCSECGMQFRCPVSLKKHMYKHTGEQLPYPCNICGKGFHINSALKNHLLRHAGIKNYVCPYCGVGKTTRQEWSKHILTHTQEKMFKCQICEHATHTKRALDNHVKIVHEKVRNYACQYCGKTFGKSHACKIHEMTHTGEKRCECKVCGKKFLYTESLTKHLKIHEKSVERAIETYRQRQVELGGSGAAAEQLPSRNTDCQLENEGNAADQLLKVCAESVATIPRDPRRVERVDIAQLAGTVVNPISAVLVPSKAPAPLNFVQKEGMHFCPGCNQGFNNLGNMKRHYKSVHEKVKDFECRFCARRFANSQSLKQHEWIHTGEKPHGCKTCGTHFRQEAALIRHQKVHDQKPPKPTKPPKQITERFRQKELQKCEKRRKVESLRLKIADAAKEELQELAKQRVLEKQHNTYEQYQAAAAAAAERTTTHPPNDPESKLLSI
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00560508;
- 90% Identity
- -
- 80% Identity
- -