Basic Information

Insect: Drosophila maculinotata
Gene Symbol: hang
Assembly: GCA_035045305.1
Location: JAWNPD010000679.1:21255695-21275402[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 17 0.35 24 5.7 1.0 3 23 527 548 526 548 0.93

2 17 0.58 39 5.0 3.6 3 22 655 674 653 674 0.89

3 17 0.00075 0.051 14.1 3.3 1 22 774 795 774 797 0.90

4 17 0.04 2.7 8.7 0.1 2 21 809 828 808 829 0.93

5 17 0.00087 0.059 13.9 0.2 2 23 956 978 955 978 0.95

6 17 0.0015 0.1 13.2 0.1 1 23 986 1009 986 1009 0.97

7 17 0.00019 0.013 16.0 0.2 2 23 1095 1116 1094 1116 0.97

8 17 0.00036 0.024 15.1 2.9 2 23 1232 1254 1231 1254 0.97

9 17 0.028 1.9 9.2 0.2 2 23 1263 1285 1262 1285 0.95

10 17 0.025 1.7 9.3 2.3 1 23 1298 1321 1298 1321 0.97

11 17 0.00016 0.011 16.3 1.1 1 23 1362 1384 1362 1384 0.99

12 17 0.0024 0.16 12.5 0.9 1 23 1392 1415 1392 1415 0.96

13 17 0.054 3.6 8.3 0.4 2 19 1423 1440 1423 1441 0.95

14 17 0.00017 0.011 16.2 0.2 3 23 1533 1553 1532 1553 0.98

15 17 0.0063 0.43 11.2 0.1 1 23 1588 1610 1588 1610 0.97

16 17 0.00074 0.05 14.1 0.6 2 23 1691 1713 1690 1713 0.93

17 17 0.29 20 6.0 0.3 3 23 1769 1789 1769 1789 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	17	0.35	24	5.7	1.0	3	23	527	548	526	548	0.93
2	17	0.58	39	5.0	3.6	3	22	655	674	653	674	0.89
3	17	0.00075	0.051	14.1	3.3	1	22	774	795	774	797	0.90
4	17	0.04	2.7	8.7	0.1	2	21	809	828	808	829	0.93
5	17	0.00087	0.059	13.9	0.2	2	23	956	978	955	978	0.95
6	17	0.0015	0.1	13.2	0.1	1	23	986	1009	986	1009	0.97
7	17	0.00019	0.013	16.0	0.2	2	23	1095	1116	1094	1116	0.97
8	17	0.00036	0.024	15.1	2.9	2	23	1232	1254	1231	1254	0.97
9	17	0.028	1.9	9.2	0.2	2	23	1263	1285	1262	1285	0.95
10	17	0.025	1.7	9.3	2.3	1	23	1298	1321	1298	1321	0.97
11	17	0.00016	0.011	16.3	1.1	1	23	1362	1384	1362	1384	0.99
12	17	0.0024	0.16	12.5	0.9	1	23	1392	1415	1392	1415	0.96
13	17	0.054	3.6	8.3	0.4	2	19	1423	1440	1423	1441	0.95
14	17	0.00017	0.011	16.2	0.2	3	23	1533	1553	1532	1553	0.98
15	17	0.0063	0.43	11.2	0.1	1	23	1588	1610	1588	1610	0.97
16	17	0.00074	0.05	14.1	0.6	2	23	1691	1713	1690	1713	0.93
17	17	0.29	20	6.0	0.3	3	23	1769	1789	1769	1789	0.97

Sequence Information

Coding Sequence: ATGTGCGACGCtgtcgcaacaacaacatcaaaaatagcagcaggaacaggagcTGGCGGAGCGGGCGATATGGCAACATTGTCAACGGCATCGGTAGGGATGGAAGAACAAACTCAACGAGAGCGACAAAGCTGCTGTCGTCTATGCATTGCCCCCGCTAGCGAATGCATTTCGATCATTAACAGTTATGCGGCCGATAAGGAGCCGCTGGCCACCAAAATACACAACTGCGTAAATATCAAGATCACGTCATTGGATCGCCTATCGCTGCATATTTGCCATGCCTGCATCAGTTATTTGAACTCCTGGCAGAGCTTCAAGAATCGCTGCCTCAGCTCGCAGTCCAAGCAGCGTCAGTGGCTCGAGACCGATAAAACCACACAGCAGACGCTACTGGGTTATTTGGATTTGAACAGGGCCGAGAATGGCAGTTCtattgaacaacaacaacagcagcaacaacaaaaacaacatcagcagcaacaacaacagcagcagcagcagcagcacgaattgaaaatcgatgcagcaacggcagccgCTGAAAAGGCATCCGCCAACATTTTGGATGGCATACCGCTGCTGAAGAAACGCAAGTCGTTAACAGTCTATGTGAGTCCTAAGCAGcaatcgcagcagcaacaacaacagcaagcaacagcaagaacgACGAGCTCGGCGGCGGAGTCGCAGCTATCGTTGGAGACCCTTTTATTGCAGGTGCCCGCAGCGACATTGGCAATGGCGTcaacacagcaacagcgcaagtatcagcagccgcagcagcaacagccgcagcagcaacaacgtggcaagcagcaacatcatcaccatcagcaacattatcaacaacaacagcagcaaaagcagcagcagcagccgcaaccacaacagcagccgcaccAGCGTCAAAGTCGCATTCATCAGCCGCGACGCCAGCAATTGTCCACGGAAGCAAAGCGTATGGCCAAATTTAAGACCAGATTGGGTTCACCATTGGACATTTCATTTCCAAcgctgccaccgctgccagtgctgccgctgccgccgccgcctgtACTTGCGACTGTTGCTGATGCAGCGCCGTTGCCTTTGCCACTGTCGCTGGCACTTGATTTCAGCCAGTGTCAGAATCCAAATGCGAATACGAATCCGAATCACAATCAATATCCGAATCGCAATCAATATCCGAATCAATGTCAGAGACCTCCAGTTGCAACAATGACCAGTAATGCCGCTTACGTTGCCGCTAACGTtgccggtgccggtgccggtgctgctgcagctccagtCACGACTCCATTGCTCATGCCGCCGCTGCCTGCCGTGCCCATCAAGGATGAGCCCCTGGACGATACGGATGATGACTTTCAAATGAAGTGCATAGACGAATCCGATGACATGATGGATCCAACAATGTTCCTAGAACGCTCCGAGCACGAGGGCGATGTGCCACTAATgACCTCCGACTATGATTATACGGCGCAGCATGGCGTGACGGCGGTTGTGGCGGCGGCATCGCTGCCCGCCAGCGCCGTTGCGAATGTGGCCGCCGCTGGCGACTCCAAGGTGGCCAGCTGCCGCGCCTGCAGTCTGCAGTTCTCGACGCGCGCGAATGCGCGACGCCATGAGCGCAATCTGCATCCGAATCTGTTCCAGCTGTCGACAGACTCGCCAAATAATACGCCCATCACAAAGCCAACGCCGGCACTGGCCGCCGCCCTGGAGATTCAGCGTGCTGCTGCCGCGGCCGCTGCCACCGCGGAGGCAACTAAAGCCGCCGCCGGTGGCAATATATCGGCCCAAAAGTATCGCCAAGTGGTCATGAACACGTTCATCAAGTGCGAGAACGGCGGCTATGACTACGACAATCCGGAGCAGTATCAGCAGCTGTTGTCGCGCGACAAGGTCGAGTTCATCCAGGAGAACAACGAGTTTCTGGAGCAGTACCAGACGATGACGTGTCGCTGCTGCAACAAATTCTTCAACACCTACAAGAACTTTATGGCGCATGTGCGCAAAAAGTATCCGCTTCTGCCGCGCAATCTATGCTTCAACTGCCTCAAGATGAACGACTCCAAGGCGCTGTTCATATCGCATCTTAAGAAGCGCAACTGCATCAATTTGTATCGCGTGCTTAACGTACTGCGCACCAAGCAGCCAAACTTTGGAGTCGCTCCAGATGCCGTCCTGACAGctgtacaacaacagcagcagctggtgacggcggcggcaacagTGGCGGCGACAGCCCATGAAACATCATCGACGGAACGACCGGAGAAACTTCGTGCCAAGGAACTGCTGGTTAATAAGCTGTACGAGTGCAAGCTCTGTCCGAAGGGATTTCGCACCAAACACGAGTTCCGCACCCATGTTTATGATAAGCATGCGGATGTGCAGCGCAAGGATAACAATTCTATACAGTGCAGCTTCTGTGGCATGGAATTTGCCGATCCGGTGGATCGACGTCGTCATTACAACAACATGGACTGCATTGTGCGACTGCGCTGCATGACCTGCGATGCCAAGTTGGAGACGCATCAGCGTTTCCTAGACCATGTCTATCAAGATCACTTGGGCGGCGTCAGCAGCGACAATGCGTCCACTGCGAACAGCGGCGTGGATCATTCGCCCGGCAAGCGTAGCCTGCTTGGCGCCCTCGGCATTGGTGTTAGTCAATCATCAAACGATGAgtcgcgcagcagcagcaacaacaacaacaacaatgtaacTGCAACGATATTAACCTCGACACCGAAACTAGcaactggagcagctgcaatagcagcaacaaccagtGGCGGCTCAACATCTGGCAGTCGCGATGCGCCTAAATCCCAGTATTTTTCGCGCATGCCACAGGTCTGCCCGATCTGTGGCCAGCAGtataacaactacaacaatgtGTTGCGTCACATGGAATCGAAGCATCCCAACAAGTTGCCCgaaacatataaatgtgtacgCTGCGGACTCGGATATCCGCGCATCTCCTATCTGCGCGAGCACATGATCAGTGTGCATGGCGTGGACAAGAATCGCCATTCGGGCGGCTTTGAGTATATTGTAAATGCGGATGCGGTTAAATTGGCGGATGGCAGCACGCCCAATGTCTATACGGGACGTTATGATTATGTGATGAAGGATCTGATGTCTATAACAAATGGTGGGACACtcgatgatgatgaggaggaACCCGGCAGCATAGCCAAAAAGATGCGACTTgatgacagcagcaacaatagcagcatCAACATGAGCATCGCCAACCAGCAGAAGGAGTGCCTCATCTGCAATGCGGTGTTCAGCAACAATATCGGACTATCGAACCATATGCGATCTCATTATACCGCCTCCACAACGACAAGTGCTGCTCTGGCTGCTGCCAATCGCATGACGCCCAAATCGCTGACAATAACCGCAACGCCGCCACTGGAGACGGCGGCCACAAGCGCTGCGGCGGTGGCACCagcggctgtggctgtggctacAACAGTGACGCCTGCCacaagcacagcagcaactacaccTGCATTAACAACATCaggggcagcagcaacgggaTCTGTAGTTGTAGCGACAAAAGTATCCGTCAGCTTGCCGCCATCGATGGTCCATCAGACGGCACAGGAGCAGGCGGTATTCCGGCGCAGTTTGGATCAGGCGGCCGATCGTCGCTTCCGTCGCATGCGATGTCGCATCTGTCAGCGCAGATTCAGCTCAAAGAAATCGTATCGCTATCACATGCTCACCGATCATCAGGTGCAGAATGTCCAGTTTATCAAATGCAAGCTCTGCAATGCAGAGTTCGCCTATGAGAAGGGCCTCAAGGTGCATCTGTTCAAGGTGCACGGACGGGCCATCAAAGATGAGATGATTATCAAGCAATTCGAGTGCGATGTCTGCTCCACTGTTTATAGCTCCGAGCTGGAGCTGCACCATCACAAGCGCAACGTGCACAAGTCACAGCTGGGCGGCAGTGATGCCTCTGCCAAATCATTGAAGTCTGCTACCGCTACCTCAGCTGACATGGCCGACACATCCGGCcaggcagtggcagcaatcCTGCCGCTCTACTGGTACCAGTGCAAGTATTGTCCATCCAACTTCAACACCAACAAGAAACTGGCCATACACATTAATTCGCACGACGAGTTCGACTCGAATGACTACTCGTGCAAGGACTGCGGCAATGTCTACAGTGGTCGCAAGAGCCTCTGGGTGCATCGCTATAAAAAGCATCCGCAGGTACCGGATCCCGCTGAGTGCACGATGTGCCGTAAGATGTTCTTCGATCGCCAAATGCTGGAGAATCACACGCCCACCTGCAATCGCAAGCCAATCACTGCCACCGGCGCCCATCAGCAGGATCAACAGCatctgcagttgcagctgcaacagcagcgggtTATCTTCAAGCACAAAACgggcgatgatgatgacgacgaggaGGACGAtgatcagctgctgctgctggacggCGGCGTCGCCAGTGATAGCAATGGTGGTGGCAATGCCATTGTAGCAGCGGCCACCAGCAAGACAAACACCACCAGTACGAGTACAATAAAGATACGCATACCGGAAGTGGCATGCACCATTTGCGGTGCCCGCTTCATCGACCAGGAGATGTTCACCAAGCACATACTGAAGCATGAACAGGATCTATATGTCGATAATCCGTTGGCGGCCATGTTTGACGATGGGCCAGCCGATGCGGGACAATTTCAGGTTGAGCGTCAGAACGAGAATGGCGAATACGCGTGCGATTTGTGCGCCAAGACGTTCCCCCAGGTGATAGCGCTCAAGGTGCATCGCAAGTGGCATTTCAGAGGTGATAGCAAGCAGAATTCAATCATCGACGGCGAAGCGACGGCGctgaacaacagcaacaacaacaacaacaattcgcTGAGCTCATCATCGATGCTGCATCTGCGCGAATTGCATGCGGTGGGTCTGATGCCCAATCAGCAGCAccagaagcaacaacagcagcagcaagaacaacaacagcagcagcaacagcaacggacAAGCAAATCGATGAAACGGAAACGTGAATTGAAATGCGAATATTGCGCCTCCACATtcattagcaacaacaacctgcGACGCCACATGTACGAGCTGCACAAACATGAGGTCAGCAATCTGCCGGAGCCGCCCGTTATTGAGGTGGATGAGCCGCTGACATGTCGCCGTTGCGGTGACCTGCAGTTCGAAACAAAGGAGCTGTGGATCGAGCATAAGCTGGCCGATGCGAAAGTTGTGCGTCCATTCTGTCCGTTCCAATGGGGCTGTGATCTGTGTGGCGACTATTTGTCGCGCAAGGAGAAGCTCATCAATCACATTAACAATCATCTTAAAGAAGATGTGATTGTGCCGGTTGCCGCAAAGCCGGTGCTGATTGCTAAAAacgcaacagcaataacaacagcaacagttgcatcTGCAAAAAGTAtaacagcagaaacagcagcagaaataataacgaaggcaacaacgacagcaggaggagcagcagctaagGAACTTAAGGCTAAGCAACAGCGGGTGCAGGCGGTGGCGGATCAGGAGGCGAATGATGGAAAGCAGCAGGAGGACGATGACAGTGATATGGATGATGATAGCGACAGTggcgatgatgacgatgacagcACCAGTGCTGACGATGATGATAACGATGACGCAGACGGCGAagtcgatgatgatgacgatgacgatgacgatgatgacgacgacgacgacggtgatgacgacgacgacgatgatgaggaAGATGTTGGagcacagcaattgctgcgacagccacaaaatgttaaaaacaacaacagcagcaacgctaTTCAAAATGAAGATGATCTCATTGAAGAGGTGGTCGAGGATGATGGCATTGTCGAGGAGCTGGAcgaagatgatgatgaggatgatgatgatgatgatgatgatgatgaggacgaCGATGATAcagatgatgacgatgatatGTCAACGGATGAGAATCCGCATCCGGCAGCCCTTAGCAAACGGCAGGGGTCGACAGAGCAGCCGAGGCGCCTCAATTTTGATTACTCGCGCACCGACAGCGCCAAGCTGAATGGTAATGGTAAACAGACGCCGGCGAAATCGAAACAGTTGCTGGCTGAGCATAGCTACGGAGAGGAGGatgtggaggaggaggaggatgatgatgaagcGATGGGTGAAGCGATGACCATTGATGATATTATTGAAGAGGTTGATGGCGAGGATGATGACGATGTGGTTGGTGTcggtggtggtgttgttgaGGACAATGATTTGGACGAGGATGATGGCGACGACGATGATCGTCGCCTGTGTCGTGTTACTGATGCTGATGGCACATCATCATCTGGGAGcgagtcaacaacaacaacatcgcaTTCAACTGGAGCTACTGCAGACACATATTAA
Protein Sequence: MCDAVATTTSKIAAGTGAGGAGDMATLSTASVGMEEQTQRERQSCCRLCIAPASECISIINSYAADKEPLATKIHNCVNIKITSLDRLSLHICHACISYLNSWQSFKNRCLSSQSKQRQWLETDKTTQQTLLGYLDLNRAENGSSIEQQQQQQQQKQHQQQQQQQQQQQHELKIDAATAAAEKASANILDGIPLLKKRKSLTVYVSPKQQSQQQQQQQATARTTSSAAESQLSLETLLLQVPAATLAMASTQQQRKYQQPQQQQPQQQQRGKQQHHHHQQHYQQQQQQKQQQQPQPQQQPHQRQSRIHQPRRQQLSTEAKRMAKFKTRLGSPLDISFPTLPPLPVLPLPPPPVLATVADAAPLPLPLSLALDFSQCQNPNANTNPNHNQYPNRNQYPNQCQRPPVATMTSNAAYVAANVAGAGAGAAAAPVTTPLLMPPLPAVPIKDEPLDDTDDDFQMKCIDESDDMMDPTMFLERSEHEGDVPLMTSDYDYTAQHGVTAVVAAASLPASAVANVAAAGDSKVASCRACSLQFSTRANARRHERNLHPNLFQLSTDSPNNTPITKPTPALAAALEIQRAAAAAAATAEATKAAAGGNISAQKYRQVVMNTFIKCENGGYDYDNPEQYQQLLSRDKVEFIQENNEFLEQYQTMTCRCCNKFFNTYKNFMAHVRKKYPLLPRNLCFNCLKMNDSKALFISHLKKRNCINLYRVLNVLRTKQPNFGVAPDAVLTAVQQQQQLVTAAATVAATAHETSSTERPEKLRAKELLVNKLYECKLCPKGFRTKHEFRTHVYDKHADVQRKDNNSIQCSFCGMEFADPVDRRRHYNNMDCIVRLRCMTCDAKLETHQRFLDHVYQDHLGGVSSDNASTANSGVDHSPGKRSLLGALGIGVSQSSNDESRSSSNNNNNNVTATILTSTPKLATGAAAIAATTSGGSTSGSRDAPKSQYFSRMPQVCPICGQQYNNYNNVLRHMESKHPNKLPETYKCVRCGLGYPRISYLREHMISVHGVDKNRHSGGFEYIVNADAVKLADGSTPNVYTGRYDYVMKDLMSITNGGTLDDDEEEPGSIAKKMRLDDSSNNSSINMSIANQQKECLICNAVFSNNIGLSNHMRSHYTASTTTSAALAAANRMTPKSLTITATPPLETAATSAAAVAPAAVAVATTVTPATSTAATTPALTTSGAAATGSVVVATKVSVSLPPSMVHQTAQEQAVFRRSLDQAADRRFRRMRCRICQRRFSSKKSYRYHMLTDHQVQNVQFIKCKLCNAEFAYEKGLKVHLFKVHGRAIKDEMIIKQFECDVCSTVYSSELELHHHKRNVHKSQLGGSDASAKSLKSATATSADMADTSGQAVAAILPLYWYQCKYCPSNFNTNKKLAIHINSHDEFDSNDYSCKDCGNVYSGRKSLWVHRYKKHPQVPDPAECTMCRKMFFDRQMLENHTPTCNRKPITATGAHQQDQQHLQLQLQQQRVIFKHKTGDDDDDEEDDDQLLLLDGGVASDSNGGGNAIVAAATSKTNTTSTSTIKIRIPEVACTICGARFIDQEMFTKHILKHEQDLYVDNPLAAMFDDGPADAGQFQVERQNENGEYACDLCAKTFPQVIALKVHRKWHFRGDSKQNSIIDGEATALNNSNNNNNNSLSSSSMLHLRELHAVGLMPNQQHQKQQQQQQEQQQQQQQQRTSKSMKRKRELKCEYCASTFISNNNLRRHMYELHKHEVSNLPEPPVIEVDEPLTCRRCGDLQFETKELWIEHKLADAKVVRPFCPFQWGCDLCGDYLSRKEKLINHINNHLKEDVIVPVAAKPVLIAKNATAITTATVASAKSITAETAAEIITKATTTAGGAAAKELKAKQQRVQAVADQEANDGKQQEDDDSDMDDDSDSGDDDDDSTSADDDDNDDADGEVDDDDDDDDDDDDDDDGDDDDDDDEEDVGAQQLLRQPQNVKNNNSSNAIQNEDDLIEEVVEDDGIVEELDEDDDEDDDDDDDDDEDDDDTDDDDDMSTDENPHPAALSKRQGSTEQPRRLNFDYSRTDSAKLNGNGKQTPAKSKQLLAEHSYGEEDVEEEEDDDEAMGEAMTIDDIIEEVDGEDDDDVVGVGGGVVEDNDLDEDDGDDDDRRLCRVTDADGTSSSGSESTTTTSHSTGATADTY

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: -
90% Identity: -
80% Identity: -