Basic Information

Insect: Drosophila maculinotata
Gene Symbol: -
Assembly: GCA_035045305.1
Location: JAWNPD010000387.1:15963135-15966812[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 18 0.11 7.2 7.3 5.1 2 23 378 400 377 400 0.96

2 18 9.4 6.4e+02 1.2 0.0 1 23 407 432 407 432 0.90

3 18 0.02 1.4 9.6 1.8 2 23 443 464 443 464 0.93

4 18 6 4e+02 1.9 3.0 2 17 475 490 474 501 0.75

5 18 0.029 2 9.1 0.2 3 23 534 554 532 554 0.95

6 18 0.00038 0.026 15.1 0.3 1 23 562 585 562 585 0.98

7 18 0.00045 0.031 14.8 0.3 2 23 590 611 589 611 0.97

8 18 0.071 4.8 7.9 0.1 1 20 619 638 619 640 0.94

9 18 0.00036 0.024 15.1 0.2 1 22 659 680 659 683 0.90

10 18 0.23 16 6.3 1.3 3 21 690 708 690 709 0.90

11 18 0.0021 0.15 12.7 0.3 1 23 728 753 728 753 0.97

12 18 0.013 0.87 10.2 1.4 2 23 769 791 768 791 0.93

13 18 0.00095 0.064 13.8 0.7 2 23 797 819 796 819 0.92

14 18 0.016 1.1 9.9 0.6 2 23 823 845 822 845 0.96

15 18 2e-05 0.0013 19.1 2.2 1 23 851 873 851 873 0.98

16 18 0.0018 0.12 12.9 0.8 1 23 877 900 877 900 0.94

17 18 2.4e-05 0.0017 18.8 0.8 1 23 906 929 906 929 0.97

18 18 0.01 0.69 10.6 0.2 1 23 933 961 933 961 0.88

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	18	0.11	7.2	7.3	5.1	2	23	378	400	377	400	0.96
2	18	9.4	6.4e+02	1.2	0.0	1	23	407	432	407	432	0.90
3	18	0.02	1.4	9.6	1.8	2	23	443	464	443	464	0.93
4	18	6	4e+02	1.9	3.0	2	17	475	490	474	501	0.75
5	18	0.029	2	9.1	0.2	3	23	534	554	532	554	0.95
6	18	0.00038	0.026	15.1	0.3	1	23	562	585	562	585	0.98
7	18	0.00045	0.031	14.8	0.3	2	23	590	611	589	611	0.97
8	18	0.071	4.8	7.9	0.1	1	20	619	638	619	640	0.94
9	18	0.00036	0.024	15.1	0.2	1	22	659	680	659	683	0.90
10	18	0.23	16	6.3	1.3	3	21	690	708	690	709	0.90
11	18	0.0021	0.15	12.7	0.3	1	23	728	753	728	753	0.97
12	18	0.013	0.87	10.2	1.4	2	23	769	791	768	791	0.93
13	18	0.00095	0.064	13.8	0.7	2	23	797	819	796	819	0.92
14	18	0.016	1.1	9.9	0.6	2	23	823	845	822	845	0.96
15	18	2e-05	0.0013	19.1	2.2	1	23	851	873	851	873	0.98
16	18	0.0018	0.12	12.9	0.8	1	23	877	900	877	900	0.94
17	18	2.4e-05	0.0017	18.8	0.8	1	23	906	929	906	929	0.97
18	18	0.01	0.69	10.6	0.2	1	23	933	961	933	961	0.88

Sequence Information

Coding Sequence: ATGTCGGAAAATTTGGAAATCAACAATTTAGAAAATGCGCCTAGCTGCCTGCATTGCAGAGTGCACGATTCAAAGCAACAATATCAAGAGATATTCGATGAAGTGGGCATTGACATAGAAATCCCTGCATTGCttcgaaaatatttcaaaataaagtgcaaaccagatgccaaaaagcaacaattaatttgtttagaaTGCTTAAATACTTTAATCCGTTTCTTTGACATCGATGAGTTGGAAAGGGAGCAGAATGCCGCCAATGCGAGGAAAAATAAGAGGGAAGAGGCTATAATATTGCTTTCacccgctgcagctgccgaCAACAAGCTGCAAAGTGAAAAGCCCGCCAAAAAgcagcatgcaacaacaaaattggcaGCACGGACAAATGAGAAGATCCCAAAGCCGGCTACTGCTGCTACTCCTCCGGTTTCCGGTCCTCCAGTGAAATCCCCTCCTGCTTCTCATTCGGAGAAATCCCTGCCTGAGTCCACGGCTATACGCATCACCAGAGCCAGAAATGAGACATCAAAACGCTTACCAGTAAGAACCATCAGGGCAAGTGAAACTCCCAAGGAGGCAGTGAAGCGGCGTGTGTCCATAGAAGTACCTGGTGGGGATCAGGAACAGATTAGCGAGCTCATACGCGACATTCTAGATGATGAACACTCGCCAGCCGATGACAAATTTGTGGAAGCAGCGGCCACAGTGCGTCAGCTGGAGAaacaggaggaggagcagcagcagctgcaagaaCAGCTGGATGAGGAGGCAttgcagcaggaggaggaggagcggcagcagctggaggaggcagctgaggaggaggaggccgTGGATGAGGAGCAACACATAATCCTGGAAGAGCAGGACAACAATGATGAGATGGAGTTTCTGCTCGAGCGTGAAGACAGCTCCTCGGAATTGGATGTGCGTCATTTCAAAGTGGAACGCAAACGCCTCTCAACGCAGTCGCAAAATGAGAGCCAAAGCGAGGATGGGTCCTTCAAAGTGGAGCCCTTCAATTTTGTGCTAATCAAGGAAAATGATAACATTGGCGATCTCTACGAGTATTTGAGCACTGTGGTGAAGACCTGCTTCGAAACGTTGCTCTTCGATTGGGCCACAGTGTGCCGTCATTGCTCGTTGAAGTGCAGCACCTATGAGAGTCTGCTCAGTCACATGCTGAAGCGTCATGAGCTGCCGGGCGAGCGCTACGAGTGTCCCATTGATGGCTGCACGACGGAGCTGCAGGGCGAATCATTGTTGGCCATGCATTTGGTGGTGCTGCATGCCCCGGTGGCGGAAATACCCATCTATGGCAGTTGTCCCGAGTGCAACATGACCTTCTCCAACATATTGCAGTACAATAAGCACTCTTGCGCCCATGTCATCAAAAAGCGACGCGGCATTCGCTTGTATTGTGAAATGTGCGGCTTGGAGTTTCCCTCGTGGAAGCGCTTTAATTTCCACAATCAATTTCATTTGGAACGCCACAGACCGCGCGCTTGCTTTGTTTGCAGCTATGCGGACAACAACATTGATGAGCTATTCCATCACTTGAACTATGCACACGAGCCAGAAGGCACGCTCTTCTGTGATCTCTGCGATCGCAACTTCCGCGATCCTGCCGTCTTTGTGGAGCACAATAAATCGCACGCAAATGTCGGCCACAACACCTACAGCTGCACCGAATGCAACGTCAACTTTGAGACACGCGGTCGCCTCAATGGTCATCTGCGCACCGCACATGGCAGCGTCATCAGCTGCGAGCTGTGCAGCCGCGAGTTTGCCACCGAAGCCACCTACAACCTACACATGAAAACGCACCTGATTATTGAACGCCAGGTGCATGTGTGCAACAATTGCGGACTGATCAGCGAACATAATGAGAAGCTGGTGGCTCATATATCGAATGAGGATTCCAGGTGCTTTGGCATGAATATCGATGTGGAAGTGCTGCGCGATGCTTATGTTTGTGAATATTGCTCCGCCTACTTTAAGCAGAAAGGCGATTTGCGCGCTCATCGCGATTCGGGCGTGCATAAGGATGGCTTGTTCTGGTGTCAGCCATGCAACAAGGAGTTCACCGACATGAAACTCTATCGTCATCACTTGCGCAACTATCAGCAATTGCGCACAGATGTTGCGCATCGCAAGCTAGAGATTTGTGTGCACTATATGTGCGATTATGAGGATTGCCCTGAGGCCTATATTAATTGGAATTCActgtacacacacaaacggCGCACACACGACGCTGCTGAGAAGCAGGAGCCCAAGACAAAAGATAACGAATGGATCTGTCAGTTCTGTCAGAAGGTGTGCCGCTCCAAAATGTCGCTATCGGTTCACGTGGCCCGCAGTCACAACAACAATAACGTGGTTTGCTCACTGTGCAATGCCTCCTATAAGAACAAAGAGGCGCTGAAAAAACATCACGCCTATTGGCATGAGCCCATGGAGTGCCCGACGTGCTTCAAGCTGGTCAAGAATCGTCGCAACTTTGACACCCACATGAATGTAGTGCACTCGAACAATAAGCGTTACACGTGCAGTGAGTGCCAGAAAGGATTCTATCACAAGAGCGAAATGGTGGCGCATCAACGGcTGCATGCCCAAATGTTTAGCTGCGAAGAGTGCAACTTCACCACGAGGAACAAGAAATCGCTGTCGGTTCATGTGATGGGACAGCACTTGAAGCGCTTCGCCTTCGAGTGCAAGGTCTGTGAGAAGCGCTTTGGACGTCGCCAGGGACTCTCGAATCATATGCAACGGGTGCATGGCTCCAATTATACGTGTCGCGATTTCATCGATGACGGCTGCAGCAAATCTTTTGAGACAACTGCACGGCTTAATGTGCATGTGCGCAAGgtgcacaacagcagcattctGCTCGCCGATGACCCAACCAAGGTGGACGCTGGCGAAGAGGAGGAAGACGAGGAGGAGGACTTGGCCAGCGATGGTCCATCCACATCGAAGAAACGTTTTATTCAGATTGAGGTCATTGACGAGGCGGCTGCGGCCGAGGATAACGACAGCCTGACGGGCTCGGAGATCCTCGAAGAGTATCAGGAGATAGCGGAAGCCGCGtcccaaccaaaaaaaaaacaaaagcgctGTTAA
Protein Sequence: MSENLEINNLENAPSCLHCRVHDSKQQYQEIFDEVGIDIEIPALLRKYFKIKCKPDAKKQQLICLECLNTLIRFFDIDELEREQNAANARKNKREEAIILLSPAAAADNKLQSEKPAKKQHATTKLAARTNEKIPKPATAATPPVSGPPVKSPPASHSEKSLPESTAIRITRARNETSKRLPVRTIRASETPKEAVKRRVSIEVPGGDQEQISELIRDILDDEHSPADDKFVEAAATVRQLEKQEEEQQQLQEQLDEEALQQEEEERQQLEEAAEEEEAVDEEQHIILEEQDNNDEMEFLLEREDSSSELDVRHFKVERKRLSTQSQNESQSEDGSFKVEPFNFVLIKENDNIGDLYEYLSTVVKTCFETLLFDWATVCRHCSLKCSTYESLLSHMLKRHELPGERYECPIDGCTTELQGESLLAMHLVVLHAPVAEIPIYGSCPECNMTFSNILQYNKHSCAHVIKKRRGIRLYCEMCGLEFPSWKRFNFHNQFHLERHRPRACFVCSYADNNIDELFHHLNYAHEPEGTLFCDLCDRNFRDPAVFVEHNKSHANVGHNTYSCTECNVNFETRGRLNGHLRTAHGSVISCELCSREFATEATYNLHMKTHLIIERQVHVCNNCGLISEHNEKLVAHISNEDSRCFGMNIDVEVLRDAYVCEYCSAYFKQKGDLRAHRDSGVHKDGLFWCQPCNKEFTDMKLYRHHLRNYQQLRTDVAHRKLEICVHYMCDYEDCPEAYINWNSLYTHKRRTHDAAEKQEPKTKDNEWICQFCQKVCRSKMSLSVHVARSHNNNNVVCSLCNASYKNKEALKKHHAYWHEPMECPTCFKLVKNRRNFDTHMNVVHSNNKRYTCSECQKGFYHKSEMVAHQRLHAQMFSCEECNFTTRNKKSLSVHVMGQHLKRFAFECKVCEKRFGRRQGLSNHMQRVHGSNYTCRDFIDDGCSKSFETTARLNVHVRKVHNSSILLADDPTKVDAGEEEEDEEEDLASDGPSTSKKRFIQIEVIDEAAAAEDNDSLTGSEILEEYQEIAEAASQPKKKQKRC

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: -
90% Identity: -
80% Identity: -