Basic Information

Insect: Drosophila maculinotata
Gene Symbol: -
Assembly: GCA_035045305.1
Location: JAWNPD010000679.1:9531597-9537024[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 9 1.1e-07 7.7e-06 26.2 1.8 2 23 141 162 141 162 0.97

2 9 1.5e-06 0.0001 22.6 1.6 1 23 168 190 168 190 0.98

3 9 1.3e-07 8.9e-06 25.9 1.1 1 23 196 218 196 218 0.98

4 9 8e-07 5.4e-05 23.5 0.7 1 23 224 248 224 249 0.95

5 9 0.00012 0.0083 16.6 3.0 1 23 254 276 254 276 0.97

6 9 0.00043 0.029 14.9 3.3 1 23 282 305 282 305 0.98

7 9 0.00019 0.013 16.0 2.7 1 23 311 333 311 333 0.99

8 9 4.5e-06 0.0003 21.1 0.8 1 23 338 360 338 360 0.98

9 9 0.0061 0.41 11.3 0.3 3 23 368 391 366 391 0.94

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	9	1.1e-07	7.7e-06	26.2	1.8	2	23	141	162	141	162	0.97
2	9	1.5e-06	0.0001	22.6	1.6	1	23	168	190	168	190	0.98
3	9	1.3e-07	8.9e-06	25.9	1.1	1	23	196	218	196	218	0.98
4	9	8e-07	5.4e-05	23.5	0.7	1	23	224	248	224	249	0.95
5	9	0.00012	0.0083	16.6	3.0	1	23	254	276	254	276	0.97
6	9	0.00043	0.029	14.9	3.3	1	23	282	305	282	305	0.98
7	9	0.00019	0.013	16.0	2.7	1	23	311	333	311	333	0.99
8	9	4.5e-06	0.0003	21.1	0.8	1	23	338	360	338	360	0.98
9	9	0.0061	0.41	11.3	0.3	3	23	368	391	366	391	0.94

Sequence Information

Coding Sequence: ATGGACACCATTTGTAGGCTCTGCTTTCAGACAGCAACGTTATTCCAAGTACCCGGTTATAGCATACCCACGTGCGTCCGCTGCTCGGAACAGTTGACAAACAATTCGAACTTTCATCAGGCGGTGCGTGTGCAGGacggtgcagcagcagcgtctgtGGCAGTAGCATCTGCAgtagccgctgccgccgcagcCTCATCGGCCGCTGCCACTGAAGGCgatgctgtggctgcggcGCAGCTGACTAACGGCAGCGCAGTGGCCGCtgtgctgcaactgcagcagcagcaacaacaacagcagcagcaacaacaacaacagcagcagcagcaacaacaattgcaatcaTCAAGTTCTTCCGAGAATCTGCAATCGCAGGACGATTCTGAAGATGTGGATCTGATATTCAACGAGGAGGGCTCCTGCCCGCTGTGCAACAAGACCTTCTCGCGCAAATCCTCGCTCATGACGCACATACGGAATCACTCGGCTGAGCGCAAGTTTGTGTGCAGCTTTTGCCACAAAGGCTTTACGCAGGCAGCCAATTTGCGCAATCACGAGCGCATACACACAAATGATCGGCCGTATCAGTGCGTGGACTGCGGCAAGACCTTTACTCAAATCACAAATCTGAATAATCATCGACGTCTGCACACCGGCGAGCGTCCCTTTGTCTGCAATGAGCCCGAATGCGGACGCAGTTTTGCACAGGTGACCAATCTGAACAATCACATGAAGTCGCACCATAAGGTGCAGCAGTATTGCTGCAACGTTTGCAGCAAGAAGTTCACGCAGGTCACCTCATTGAATCAGCATCTGCAGGCGCATGCCGGCGTTACCGGCTACTATTGCCCGCGCTGTCCGGAGAAGAACTTTAAGCTGCAATCGCAGCTGCATACGCACATGAAGACGCATGGCTTGGCCTTTCCCTACGAGTGCAGCAAGTGCGATGAGAAATTTCTGCAGCAGTCGCATCTTGATCAGCATCTCAAGATGCACGATGagttcaaattcaaatgcgaCATATGCCCCAGCAGCTTTAACCAGGAGTCGCTGCTCAAGAAGCATGTGCAGCGCCATGTCGAGGGTCGCTACCTCAACTGCCCGGTGGCCAACTGTGCCGAATCGTTTGCCGTGCGACAGCATCTCTCCAAGCACTTGCTCACCAATCACTCACACCACGAGCTGCCGCCACCGAAACGCTCCAAAAAGACCGTCACATTGCAGTCGCCGCAACAGCCGCTGGCCATGATCGGGCAGCCACTATCGCTGCAGCATACGACGGGGCAGCGTGGCAGACCGccaaaaaacaagaacaagacCTCACTGGCAGCCACGGCCATTAAGATTGAGATCAACGAGCCGTTGCACAGTCAGCATATTATCAGCAGTGCCAGCGGCCTCTCCATACAGCAGCAGATCAATCAgcatatgcagcagcagcagcagcagcaacaacagcaacagcagcagcagcagcaacatcttcATTTGCCGATGGGACAAGCGGTCAAGGCACGCTTTATACCCACTAaatag
Protein Sequence: MDTICRLCFQTATLFQVPGYSIPTCVRCSEQLTNNSNFHQAVRVQDGAAAASVAVASAVAAAAAASSAAATEGDAVAAAQLTNGSAVAAVLQLQQQQQQQQQQQQQQQQQQQQLQSSSSSENLQSQDDSEDVDLIFNEEGSCPLCNKTFSRKSSLMTHIRNHSAERKFVCSFCHKGFTQAANLRNHERIHTNDRPYQCVDCGKTFTQITNLNNHRRLHTGERPFVCNEPECGRSFAQVTNLNNHMKSHHKVQQYCCNVCSKKFTQVTSLNQHLQAHAGVTGYYCPRCPEKNFKLQSQLHTHMKTHGLAFPYECSKCDEKFLQQSHLDQHLKMHDEFKFKCDICPSSFNQESLLKKHVQRHVEGRYLNCPVANCAESFAVRQHLSKHLLTNHSHHELPPPKRSKKTVTLQSPQQPLAMIGQPLSLQHTTGQRGRPPKNKNKTSLAATAIKIEINEPLHSQHIISSASGLSIQQQINQHMQQQQQQQQQQQQQQQQHLHLPMGQAVKARFIPTK

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00533229;
90% Identity: iTF_00572743;
80% Identity: -