Dmac003424.1
Basic Information
- Insect
- Drosophila maculinotata
- Gene Symbol
- -
- Assembly
- GCA_035045305.1
- Location
- JAWNPD010000329.1:965254-970047[-]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 15 2.2e-05 0.0015 19.0 1.3 1 23 151 173 151 173 0.97 2 15 0.00091 0.062 13.9 1.2 3 23 181 201 179 201 0.94 3 15 9.9e-05 0.0067 16.9 0.1 1 23 361 383 361 383 0.98 4 15 0.00027 0.018 15.5 0.8 1 23 389 412 389 412 0.98 5 15 0.00011 0.0078 16.7 6.0 1 23 442 464 442 465 0.95 6 15 0.0005 0.034 14.7 2.4 1 23 499 521 499 521 0.95 7 15 0.0094 0.64 10.7 0.4 1 23 527 550 527 550 0.98 8 15 0.029 2 9.1 0.4 3 19 559 575 558 576 0.95 9 15 0.00017 0.012 16.1 5.6 1 23 585 607 585 607 0.97 10 15 0.028 1.9 9.2 0.4 2 23 613 634 612 634 0.96 11 15 1e-05 0.00068 20.0 1.0 1 23 643 665 643 665 0.98 12 15 0.0011 0.077 13.6 0.1 3 23 673 693 671 693 0.97 13 15 6.1e-05 0.0041 17.6 0.5 1 23 699 721 699 722 0.95 14 15 0.3 20 5.9 0.3 1 23 732 754 732 754 0.96 15 15 0.00052 0.035 14.6 0.5 1 23 1274 1296 1274 1296 0.98
Sequence Information
- Coding Sequence
- ATGAACAATCAGGACTATGGCGGCATCCAATGGATACAGCAGCACTCCTCCGCAATTGATTCTGAAACGGAAATGCTGGAAACGGGTGAAGTGACAACCGCTTATCTGGTTAACTGTAACGGTAATGAAACAGACGAGGATCTCGATCATATGGCCGCCGAGAATCTCATCTTTATGGCCCGCGACGGTCAGCTGAGCGAAATCATCGCCGCCAGTGAAGCGGGAGGTGGGGGAGGGACCGTTTTAATAACGGACAGTGGGAATGTTGCCTTTGCGGTGGAATCCTTCGAGGATGATGCCCAGGTGGTCACCGAGGAGATCATCACCGATGACTGGGTGCAGCACCAGGGAGCCGAGCGTGTGGAAATTGCGGCGGAACAAATTGCGGGCAATGGCAGCTCGCAGGAGCTGCTGGACATGGAGCAAGATGAGTACACGGCGCTGCGTCCGTATCCCTGTGACTTCTGCAGTCGGCGCTTTCGCAAAAAGGCCAGCCTCAATAATCATATGCAGGCGCATCAGAACGATCGTCCGCATCTTTGCAAGTTGTGCGGCGCTCGCTTCTCGCGACGCGCCGAGCTCATCAGTCACTTTAAAGCGCATGCCGAGGCTCAGGCAGATGCCGAAGAcgccgcagctgcagcggtTAAATTcgagccgcagcagcagcagcgacaagtAGACGAGCATTTCTACGAACAGGAATGGTATCAGGAACAAGAACAGTTGCAGGAGCATGACCAATCGTCGCAACTGGAACAGGAaccggagcaggagcagctgtcGGTTGCCAGTCAAGTGGTGCAACAGGCCAGCTATGCATCGGTCAGCGCTGTGGCAGCACCAACAGCGGCGCGTGGACGCATCAGTCGCCTCAAGCTCAAAGAGGAGAGCACGCAGTACATTATGATTGCCGAGAAACAGGCAACGGATGAATTGCGCCAGTACATCGATAGCAAGGAGCTAACGCCACCGCCAACTGGCAACGCACCAAACAATGCAGCGCACTCGACCGAAAGCCCAACTGCTCCTGATCCAACGCCAACTCTGCGCTTTCCCGTGCTGGACGAGAGCAAACCCTTCGTCTGTCAGCAATGCGGCTTGGCATTTGCGCGTGAGAAGGCGCTCGTCTCTCACATCAAGAATCATCGTGTTGACTCACCGTTCGAATGCAATCAGTGTCAGGAGATGTTCTGGGACAATTACAGCCTGCAGGAGCATCAGAGGACGAATCATTTCGAGGAGAGCAACTCGGAATATGATCCGGCATCGGCGGGCGAGGACAGTGCCAGTGAATCAGAGCAGGAGCAGCTATACGGTGACTTCTACTGCAACCAGTGCGGCATTTCCTTTCACAGGCAGGACCTGCTGCGTCGCCATACCAAACAGCATCACAAGCTGGTGCCAGTGAGCAAAGCTACGGCCGCATTGCTCAGCTCAACATATGTCGAGGGCGACGGCGAATGCGATACAGACAATGCCAAAGATGCACCACACTGTTGTCATACGTGCGGCAAGTCATTTCCCAACGCACTGGAGCTGCTAGCCCATGCCGAAATGCATGCACGTTTCCCGCCATTCAAATGTGTTCTGTGCGGTGTCAGCTTCTTCGAGGAACAGGCTATCAAACGGCATCTGAACACTCGTCATTCGCATGAGCTGAAGCCCAACTCGTGCGTGTTGTGCGGCAAAGAGTGCCGTGATCGCAAGGCGCTGATTAAGCACGCCTGGGATCACTCGCGTGAGAAGTGCCACTCGTGCTCGAAGTGCGGCAAGAACTTTCACAACAAGGCGCGCCTGAAGCGGCACATGGCATCGCATCGCGATAAGTCGGTGGTGTGCGAGGTGTGCAACGAGGAGTTCCCCGATGGCCGCACGCTCTCTAATCATCGCCACTCGCACAGCACCACGTCGCCGGGTAAACTGTTCCCCTGCCATGAGTGCGGCAAGACCTTTGGGTCGCGCAGCTCCCAGCAGATTCATGTGCGCATTCACACCGGCGAGCGGCCCTATGGCTGTCGCTATTGCTGGAAGGCATTCGCCGATGGCGGCACTTTGCGCAAGCACGAAAGGATTCACACGGGAGAGAAGCCCTACGCCTGCTCCGTGTGTCCGCGTGCCTTTAATCAGCGTGTCGTGCTGCGCGAGCACATACGCTCCCATCACTCAGGTCTGGATGCTTCACGCGGCACCTATCACTGCACCGTCTGTGAGGCGGATATGTCCACGTCGAACGAGCTCATACAGCATCTCATACAGCACAGCGACTCGAACACTGCAAAGCAGCGACAGCCCATTACTGGTCCTCGCAAGTACAAGCGACGAAGGAAACTACAGCCACATGAGATAGCACACATGCGCGCTGATCACAAGGATGGCGAGGAGTATGCTAGCGAGATGGAATACTGCGACTTGGATGTGGAGAATGTGGACGATCTCCTGGACAGGGCCGAGCCCTTGCCAACCAAAAAGGAGAAGCGCAAACGTAACGCTGCCAGTCAAGCCAAAACAGTGGATATTGACACTGAGGCGACTTCTCCCATCAAATCCGCCAATAACAGTTCCGATCGTCTGTGGGATGAGAAATTCCTGCAAGCAAATGGTAATGCAAATCAACTTAATGATGATGCATACAAGAGTTTCTTTCAAATTGACTCGCTGGTGGTTGTGAATGATACCACGTTGCAGCCGGTGAGTTCAGTCAGCGGTAGCCGGGCCTCTAAGTCGCGACGCAGTGGCAAGCAGACGCAGGCGGAGAGCTGTGATaaatcaacagcagctgctgatgaGTCTAGTAAATCCAGTGGCtccagcagtcgcagcagcaaaaagaagTCCAGCAAATCAGGCAAAAGCTCAGCGACAACACCAGCTGGCACTTCTGGTAGCTCGCGTCCCCGCATGATACACACTGAAATTTCACACGCACCGCCGGAGAATTCCTCGAAGAAGTCGCGCGGACGCAGCTACATTACGCGCACCAACACCAGCGAGAGCAGCCAGCTGGGTGGTCTGGTCAAGTCCAGTGGCGTTGCCAGTTCCCGTATAGTGGATGACTATGAGATTATATCACCCGCCACACAGCCGCCCAATCAGATCAGCTCCAGTCCACTGCACAtcaagcaggagcaggagcatcagcagcaccatcatcatcatcatcaccatcagcagcagcagcaacgcgtTCAGCTCATGTACGATGATACGCATCTGCTGATCGATGCAGGACTCTTGCGCGAAAAGACCTACGAGAAATTCAATCCAAGCATTGTCAATGATCTGGAGGAGATCTTACGTAGTCCGCTCAAACATGATCGCAATTCGCGGCTGCGCTTTACCAGCGAATCGTCGACAACGCCACAGTTTTTGCCCGAGGAGGAGCAGAACCTCATCAAAATAGAGCCCACATCGCCGGATCTGCGCGAAATGGTCGAGAGCCAGCAGCGTGTAACTGCCACAGGACACACAGCCACAccctcatcatcgtcatcatcatcggcgCGCACATCGCGTCATCTGCGACAGCTCACTACCAATTCCGGCTCACGAGCAACAGCCAAGCGTAGTGGTAGCAAAAATATGTCCACATCCGGCTCAAAGAAATCGACTTCAGTCTCTTCTGTTGCCGCCAGCAAACCCAACTCGTACCTCAGCTATGGCGTGGACTCGTACAATGTGAATGTGGCAGTCAGCGCGAACTCCTCAGATGTCAGTTCCGGTTTCTTTTCCATCTCGGAGGTGGTGTCCGCGGCGGATGCCGCCGATGCAGCGGCCAAGGCAGCAGCGGCCAACAAAACGCAGCGTAGGACGCGCTGCTTTGAGTGTGAAATGTGCTCGTCTATTTTTCCCGATCGCTCCCAGCTGCTggaacatatgcatatacacatCTAG
- Protein Sequence
- MNNQDYGGIQWIQQHSSAIDSETEMLETGEVTTAYLVNCNGNETDEDLDHMAAENLIFMARDGQLSEIIAASEAGGGGGTVLITDSGNVAFAVESFEDDAQVVTEEIITDDWVQHQGAERVEIAAEQIAGNGSSQELLDMEQDEYTALRPYPCDFCSRRFRKKASLNNHMQAHQNDRPHLCKLCGARFSRRAELISHFKAHAEAQADAEDAAAAAVKFEPQQQQRQVDEHFYEQEWYQEQEQLQEHDQSSQLEQEPEQEQLSVASQVVQQASYASVSAVAAPTAARGRISRLKLKEESTQYIMIAEKQATDELRQYIDSKELTPPPTGNAPNNAAHSTESPTAPDPTPTLRFPVLDESKPFVCQQCGLAFAREKALVSHIKNHRVDSPFECNQCQEMFWDNYSLQEHQRTNHFEESNSEYDPASAGEDSASESEQEQLYGDFYCNQCGISFHRQDLLRRHTKQHHKLVPVSKATAALLSSTYVEGDGECDTDNAKDAPHCCHTCGKSFPNALELLAHAEMHARFPPFKCVLCGVSFFEEQAIKRHLNTRHSHELKPNSCVLCGKECRDRKALIKHAWDHSREKCHSCSKCGKNFHNKARLKRHMASHRDKSVVCEVCNEEFPDGRTLSNHRHSHSTTSPGKLFPCHECGKTFGSRSSQQIHVRIHTGERPYGCRYCWKAFADGGTLRKHERIHTGEKPYACSVCPRAFNQRVVLREHIRSHHSGLDASRGTYHCTVCEADMSTSNELIQHLIQHSDSNTAKQRQPITGPRKYKRRRKLQPHEIAHMRADHKDGEEYASEMEYCDLDVENVDDLLDRAEPLPTKKEKRKRNAASQAKTVDIDTEATSPIKSANNSSDRLWDEKFLQANGNANQLNDDAYKSFFQIDSLVVVNDTTLQPVSSVSGSRASKSRRSGKQTQAESCDKSTAAADESSKSSGSSSRSSKKKSSKSGKSSATTPAGTSGSSRPRMIHTEISHAPPENSSKKSRGRSYITRTNTSESSQLGGLVKSSGVASSRIVDDYEIISPATQPPNQISSSPLHIKQEQEHQQHHHHHHHHQQQQQRVQLMYDDTHLLIDAGLLREKTYEKFNPSIVNDLEEILRSPLKHDRNSRLRFTSESSTTPQFLPEEEQNLIKIEPTSPDLREMVESQQRVTATGHTATPSSSSSSSARTSRHLRQLTTNSGSRATAKRSGSKNMSTSGSKKSTSVSSVAASKPNSYLSYGVDSYNVNVAVSANSSDVSSGFFSISEVVSAADAADAAAKAAAANKTQRRTRCFECEMCSSIFPDRSQLLEHMHIHI
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- -
- 90% Identity
- -
- 80% Identity
- -