Basic Information

Insect: Drosophila maculinotata
Gene Symbol: ZNF532
Assembly: GCA_035045305.1
Location: JAWNPD010000335.1:22785233-22790551[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 26 0.0019 0.13 12.9 2.0 1 23 223 245 223 245 0.96

2 26 0.011 0.75 10.4 2.3 1 23 251 273 251 273 0.98

3 26 0.34 23 5.8 1.0 2 23 305 326 304 326 0.95

4 26 3.3 2.2e+02 2.7 5.2 1 23 400 423 400 423 0.89

5 26 0.99 68 4.3 0.7 2 22 435 455 434 455 0.93

6 26 1.3 91 3.9 1.2 1 22 464 485 464 488 0.89

7 26 0.095 6.4 7.5 0.5 1 23 501 523 501 523 0.98

8 26 0.003 0.21 12.2 0.2 1 23 597 620 597 620 0.95

9 26 0.0035 0.24 12.0 0.1 1 22 629 650 629 650 0.95

10 26 0.017 1.1 9.9 6.7 1 23 659 681 659 682 0.95

11 26 0.00031 0.021 15.3 0.3 2 23 712 733 711 733 0.97

12 26 4.1e-06 0.00028 21.2 2.8 1 23 741 763 741 763 0.98

13 26 0.012 0.81 10.3 1.5 1 23 914 937 914 937 0.95

14 26 0.0075 0.51 11.0 1.0 2 22 945 965 945 965 0.96

15 26 0.11 7.8 7.3 0.4 1 23 974 997 974 997 0.92

16 26 6.3e-05 0.0043 17.5 1.6 1 23 1022 1044 1022 1044 0.97

17 26 0.00034 0.023 15.2 0.9 1 23 1051 1073 1051 1073 0.98

18 26 0.0078 0.53 10.9 0.0 2 21 1100 1119 1099 1120 0.94

19 26 0.037 2.5 8.8 4.8 1 23 1165 1188 1165 1188 0.96

20 26 0.00079 0.054 14.0 1.0 1 23 1225 1248 1225 1248 0.95

21 26 0.015 1 10.0 3.1 1 23 1273 1296 1273 1296 0.97

22 26 1.4e-05 0.00098 19.5 0.1 2 23 1321 1342 1320 1342 0.95

23 26 4.9e-05 0.0033 17.9 2.9 1 23 1348 1370 1348 1370 0.99

24 26 2.4e-06 0.00016 22.0 2.0 1 23 1376 1398 1376 1398 0.97

25 26 6.1e-08 4.2e-06 27.0 2.4 1 23 1404 1426 1404 1426 0.99

26 26 0.00073 0.05 14.2 0.3 1 21 1432 1452 1432 1456 0.91

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	26	0.0019	0.13	12.9	2.0	1	23	223	245	223	245	0.96
2	26	0.011	0.75	10.4	2.3	1	23	251	273	251	273	0.98
3	26	0.34	23	5.8	1.0	2	23	305	326	304	326	0.95
4	26	3.3	2.2e+02	2.7	5.2	1	23	400	423	400	423	0.89
5	26	0.99	68	4.3	0.7	2	22	435	455	434	455	0.93
6	26	1.3	91	3.9	1.2	1	22	464	485	464	488	0.89
7	26	0.095	6.4	7.5	0.5	1	23	501	523	501	523	0.98
8	26	0.003	0.21	12.2	0.2	1	23	597	620	597	620	0.95
9	26	0.0035	0.24	12.0	0.1	1	22	629	650	629	650	0.95
10	26	0.017	1.1	9.9	6.7	1	23	659	681	659	682	0.95
11	26	0.00031	0.021	15.3	0.3	2	23	712	733	711	733	0.97
12	26	4.1e-06	0.00028	21.2	2.8	1	23	741	763	741	763	0.98
13	26	0.012	0.81	10.3	1.5	1	23	914	937	914	937	0.95
14	26	0.0075	0.51	11.0	1.0	2	22	945	965	945	965	0.96
15	26	0.11	7.8	7.3	0.4	1	23	974	997	974	997	0.92
16	26	6.3e-05	0.0043	17.5	1.6	1	23	1022	1044	1022	1044	0.97
17	26	0.00034	0.023	15.2	0.9	1	23	1051	1073	1051	1073	0.98
18	26	0.0078	0.53	10.9	0.0	2	21	1100	1119	1099	1120	0.94
19	26	0.037	2.5	8.8	4.8	1	23	1165	1188	1165	1188	0.96
20	26	0.00079	0.054	14.0	1.0	1	23	1225	1248	1225	1248	0.95
21	26	0.015	1	10.0	3.1	1	23	1273	1296	1273	1296	0.97
22	26	1.4e-05	0.00098	19.5	0.1	2	23	1321	1342	1320	1342	0.95
23	26	4.9e-05	0.0033	17.9	2.9	1	23	1348	1370	1348	1370	0.99
24	26	2.4e-06	0.00016	22.0	2.0	1	23	1376	1398	1376	1398	0.97
25	26	6.1e-08	4.2e-06	27.0	2.4	1	23	1404	1426	1404	1426	0.99
26	26	0.00073	0.05	14.2	0.3	1	21	1432	1452	1432	1456	0.91

Sequence Information

Coding Sequence: ATGTTGCCGACTGATATTTGTCGCACGTGTGCGCTGCAAGCTGATAATTTGTTGGTACTCTCGAAGCGCAGCATAAAATACGCAAAGAAAACTATTTGCGACATGTTGCAAGAATTAACACAAAACGATCCGCTGCTGGAACAACCCGATGATAATCTACCGCAGCAATTGTGTGAAGGATGCTTGCTCCAATTAGAAGCAGCCTACGGTTTTATCCTGCAGGCTCGTCAGGCACAGGAtcaactgttgctgcagctacGCAGAGAATTGCAGACAGAGTGTCTGGACGAGACGCCCATTGATATTTCAATGCAGCACATTAAAGCCGAAGCAGACATTGACTTGGATGGGAAAATGGAAGACGCAGCGCCACTGGATGAGGGGGTGGAagaggatgcggatgcggaggAGAATGTATCTGCTGTGTCTGTTGCTGCCTTAAAGTGGCAGCTGTCAAGTGATAGCGACAGCAGTCAGGCAAACATTGATGACCACGATGTGGACTTTCAACCCACGCAGCTGCGTCGCAGCTTACGGAATGCCAGATTGAGCACAGATAGCGAAAATGAGTCGACCTCTGCCCATGCGAAGCTGCTGCCTGTCAAGCGTCGACGTGGACGTCCTACACGCCTGGCCAAAAAGGATACCATCAACGAGGATGGTCGGCATGCGTGCGAGGTGTGCGGCAAAACTTTTTCCTGGCATCGCGACATGCAGCGCCATGCAAGAATCCATTTTGAGCAGGCGGCCTATGTGTGCGAGAGCTGCGGCAAGAGTTTCCTGCGCAAGGACAAGTACACGTTCCATCTGCGCACACACGAGAAGCGCGCAGCCAAAGTGCAGGCGCTGCAGCTGAGCAGCGAATGGCGCTTCGCGGAACGACTCTACGGCTCCGGTCGCCTAAAGCGGGTAGAATGCAAGCTGTGTGGTCTGAAGTGCCAGCGAATTCTGGAGCTGCGCGAGCATCTGACGAGTCACGTTAGCGTGGACACACTGTCAAATCTCCGCTTGGAGAGTGATGTCATCAGGGAGCAGTTTGACAGCGAGTTGAGTTTGCAGCAAATAAAGGAACAGTTGTGCGCTCAAATTGCCAAGGGACGCGAACAGCTGGACAAATTCTGTGCCGTGGTCAATGCTTATGGCTACGAGCTGTGCCTTAGCGACTCGGATGAGGAGTTGGCGGGCATGGTGCCTCCATACCACTGCCTGCCCTGCAACGTCCACTTCACACGCAAGCACCGCCTCGTGCGGCACACGCTGGAGGAGCACACACAAAACGATGGAACTGCGACAAATTGGCAGCGCTGCACTGTCTGTCAAATTGGATTTACTTGCGCCCGGCTGTTGGAGCAGCATCAGAGCACGCAGTGCCTTAATCCGCTAAAGCGGTACAGCTGCGAAAATTGTCCTGGCAAATTCATTTGGCGGCAGAATCTACAGCAGCATGCGTGCAGTAGACTGCATCAGAAGCAGGATCAGGAGCAGCATTATCATCGTCAGTTTCAGTGCTGCCTGTGCGATGCTCAACTAGACAGCATGGCTGCCTTGCGCTCACATTTGCTCACCCATCGCGATGGACGCAGCGGCATCGATCCGCAGCAGCAGTCTGCCTTCTTTCGCACCTATTATCCGGATGGAATCGGCAGCAGCTTTGAGGAGCTGAGTGCACGCATTTCCAGCGACTTTGAGGCGCATGATTATGGACGCTACTTCAATGCCTGCACGGACAGTGGCCAGGAGCTGGATTTCTACGACTCCGACACGGATTTAAGTGATGCTCCTGCTCAGCATATCTGTGCCCTATGTGGAGAGAGCACAGCCCGCCTcgcacagctgctgcagcatcagcagaGCCAGCACAACGAATTGGAAGTCAGACTGCCTCATGTCTGCGCGAATTGTGGCTTGAGCTTTGTGGCGGAGTCGCTGCTCCAGCAGCATCGCCGTCGCGTCTGCGGCAAGCAGCATTCAAAATACCATTGCCCGCATTGCAGTCTGTTCTTCAACTGGCAATCCAACTATGAGCGGCACATGCAGCTGCACCACACCGCGGACACGGAAGAGGCACAGAATCAGGATCAGGAGCCTAGTGGCAGGTTGAGAAGCAAGCGGCATACAGCACTTGCCAAGCTGCAGTGCAGCGAGTGCGAAAAGGTCTTCATCTGGCCAAAGGATCTGACGCGGCACAAGCGCATTCATCGGCCTCAGGCATTGGCGCAGTTCGAATGCGCATACTGCGATCGCAAGTTCCATCGCAAGGATGGCCTCAAGTCTCATATGCGAGTACACAgcgaacagcagcagttggagGCGACGGCAATCAGCGAGCAGCAATCGACGGTGCTGCAGCGTATGCCAGTGGTTTTAACCCAACTGTGCCGGCCCAATGGCTGCAAGCAGATTCAGTGCATGATCTGCCTCTCGCAGCACACAAAGATCTCCGATCTGCGAACGCATTTAATCAATCATCAATATGCGCTGAAGTTTGCGGAGGAGCGTGGCAGGCCGGAGAGTATTGCGAGCCTTTGCCGTGTCCTCTACCCGGAGTTAACTACGCCGCTTGAGCAGCAGGATCTGATTAAGCGCATTCAATTCGATCTAGCCAAAGGCCTGGAACTGGAAAGATTCATTTCGATTACGAACGAGGCGGGCATGGAACTGAGTCTGGACAGCAGCGAAACGGAAACGGATTCCGATTCAGCAGAGCCactaagcagcagcagtcgcagtgGACGCCTGTACAGCTGTGAGCTGTGCCAGCTGCAGGTGACACGCAAGCATCAGCTCTATGCCCACCAGCTGGAGCAGCACACATGGCAGCAGGCGACGCGCGTGTGCAGCCACTGCCAGGCGAGATTTGTGaatgagcagctgctggagcatCATTATCGCACACTCTGCCGCAATGCCCAGCGGCGTTTCCTCTGCCGCAAGTGTCCTCTACGCTTTCGGTGGCGTGAAAACCTTAAACTCCATACGGCCGTGGCACATCAGGAGGGAAATATTGAACATTCCAATTTGGCCATTCAGTTGAATGGCTCGCGTCTGCTGCCCGTGGTTAGCTACGATTGCGTCGAATGCAAGCGCAGCTTCAAAATGCAAAAGGATCTCACACGACACACGCTGATGCATGCCCAGGAGTCGAGCATCTATCGTTGTCGCTGGTGTGCAAGACGCTTCTATCGCCAGCCTAATCTGCTGCAGCACATCGAGCGGCATGGCATCAGCGCCGAGCAGCTGCCCTATGCGGAGGCGCTGCTCAATGCCAGTCGGCATCCCCATGGCCAGAAGCGCATACAATGCAAGGTGTGCGAGGTGTCCTTCTCCAGCATTGCTGCATTGCGTTCACATCTGCAGTTGGCGCCAGCGGGCACACATCATGAGATAAACTCCATGCTTAACTATTCGATTACCAATCAGATGGGCTACGAGCTGCATTTGAATGACTCGGAAACGGACGAGGAGTGCAAGCCGGAGGGCACACCTGCCCAATACACCTGCAGCATGTGCCAGCTGCGTTGTGTGCGCAAATTTGagctgcatcagcatcagcaggcgATGCATCGGCTGGAGCGGATCAGTGAGGGCTGCTCGGAGTGCATCTTCAAGAGCGTCTCGCCGGATTTGATTGCTCATCATCGGCGCATGCTGTGCGGCAACACGGAGAAGCAGTTTAAATGCCCAAAATGTAGCTACAAGTTCATGTGGCAATCGAATCTTGAGCAGCACATGGAGCTGCAGCATCCCAGCAGCGATGACCAGCAGGAGACGACATCAAACCCTATTCCAAATATTTCCAGCGCTGAAAGCCAGATCTTCCAGTGCGGTCAGTGTCCCAGTAAATATAATCGCAAGGATCGCCTCACCGCACATGTGAAAAAGTGTCATGCAGTTGGAGCAACTGCTCCCTCCACGAGGCAAACAAAGTCGCCGGCAGCTGTCAAGCAGCAGAAAAGTTTCCTATGCGCCTTCTGCGGCAAAGCGGTGAGCTCCTCATCCAATTTAATCATACATATTCGTCGGCACACCGGCGAGAAGCCCTTCAAGTGTGACTACTGCGACATGGCCTTTCCGCGCTCCTCCGATCTCCAGTGCCATCGACGCACCCACACAGGCGAGCGTCCTCACGTCTGCACCGTCTGCCAAAAGGGATTCGCCCGCTCCtacaagctgcagcagcacatgCGCATCCACAATGGCGAGCGGCCCTACAAGTGCACCTACTGTGACAAGAGTTTCACCCAGTCGAATGATCTCACGCTCCACATCCGTCGGCATACGGGCGAGCGTCCCTACCAGTGCAATACGTGCGGCGAAAGATTCATTCAGGGCACTGCGCTCAAAAATCATCGACTGCAGAATGGCCATTACGAGACGGAAGCGGAACCACTGAAAGATGACTAA
Protein Sequence: MLPTDICRTCALQADNLLVLSKRSIKYAKKTICDMLQELTQNDPLLEQPDDNLPQQLCEGCLLQLEAAYGFILQARQAQDQLLLQLRRELQTECLDETPIDISMQHIKAEADIDLDGKMEDAAPLDEGVEEDADAEENVSAVSVAALKWQLSSDSDSSQANIDDHDVDFQPTQLRRSLRNARLSTDSENESTSAHAKLLPVKRRRGRPTRLAKKDTINEDGRHACEVCGKTFSWHRDMQRHARIHFEQAAYVCESCGKSFLRKDKYTFHLRTHEKRAAKVQALQLSSEWRFAERLYGSGRLKRVECKLCGLKCQRILELREHLTSHVSVDTLSNLRLESDVIREQFDSELSLQQIKEQLCAQIAKGREQLDKFCAVVNAYGYELCLSDSDEELAGMVPPYHCLPCNVHFTRKHRLVRHTLEEHTQNDGTATNWQRCTVCQIGFTCARLLEQHQSTQCLNPLKRYSCENCPGKFIWRQNLQQHACSRLHQKQDQEQHYHRQFQCCLCDAQLDSMAALRSHLLTHRDGRSGIDPQQQSAFFRTYYPDGIGSSFEELSARISSDFEAHDYGRYFNACTDSGQELDFYDSDTDLSDAPAQHICALCGESTARLAQLLQHQQSQHNELEVRLPHVCANCGLSFVAESLLQQHRRRVCGKQHSKYHCPHCSLFFNWQSNYERHMQLHHTADTEEAQNQDQEPSGRLRSKRHTALAKLQCSECEKVFIWPKDLTRHKRIHRPQALAQFECAYCDRKFHRKDGLKSHMRVHSEQQQLEATAISEQQSTVLQRMPVVLTQLCRPNGCKQIQCMICLSQHTKISDLRTHLINHQYALKFAEERGRPESIASLCRVLYPELTTPLEQQDLIKRIQFDLAKGLELERFISITNEAGMELSLDSSETETDSDSAEPLSSSSRSGRLYSCELCQLQVTRKHQLYAHQLEQHTWQQATRVCSHCQARFVNEQLLEHHYRTLCRNAQRRFLCRKCPLRFRWRENLKLHTAVAHQEGNIEHSNLAIQLNGSRLLPVVSYDCVECKRSFKMQKDLTRHTLMHAQESSIYRCRWCARRFYRQPNLLQHIERHGISAEQLPYAEALLNASRHPHGQKRIQCKVCEVSFSSIAALRSHLQLAPAGTHHEINSMLNYSITNQMGYELHLNDSETDEECKPEGTPAQYTCSMCQLRCVRKFELHQHQQAMHRLERISEGCSECIFKSVSPDLIAHHRRMLCGNTEKQFKCPKCSYKFMWQSNLEQHMELQHPSSDDQQETTSNPIPNISSAESQIFQCGQCPSKYNRKDRLTAHVKKCHAVGATAPSTRQTKSPAAVKQQKSFLCAFCGKAVSSSSNLIIHIRRHTGEKPFKCDYCDMAFPRSSDLQCHRRTHTGERPHVCTVCQKGFARSYKLQQHMRIHNGERPYKCTYCDKSFTQSNDLTLHIRRHTGERPYQCNTCGERFIQGTALKNHRLQNGHYETEAEPLKDD

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00508485;
90% Identity: -
80% Identity: -