Dmac014767.1
Basic Information
- Insect
- Drosophila macrospina
- Gene Symbol
- -
- Assembly
- GCA_035042075.1
- Location
- JAWNLW010000593.1:2357614-2361278[-]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 17 3 2e+02 2.7 9.0 2 23 352 374 351 374 0.95 2 17 0.73 48 4.6 0.4 1 23 381 406 381 406 0.91 3 17 0.13 8.3 7.0 4.2 3 23 418 438 417 438 0.93 4 17 3.6 2.4e+02 2.4 2.3 2 17 449 464 448 475 0.77 5 17 0.059 3.9 8.1 0.7 1 23 506 528 506 528 0.94 6 17 0.00021 0.014 15.8 0.3 1 23 536 559 536 559 0.98 7 17 0.091 5.9 7.5 2.0 2 23 564 585 563 585 0.96 8 17 0.00039 0.025 14.9 0.4 1 22 633 654 633 657 0.90 9 17 0.31 20 5.8 1.8 3 21 664 682 664 683 0.91 10 17 0.0066 0.43 11.1 0.9 1 23 702 727 702 727 0.96 11 17 0.022 1.4 9.4 0.7 2 23 744 766 743 766 0.93 12 17 0.0094 0.61 10.6 0.2 2 22 772 792 771 794 0.88 13 17 0.047 3.1 8.4 0.3 2 23 798 820 797 820 0.96 14 17 0.00021 0.014 15.8 2.7 1 23 826 848 826 848 0.98 15 17 0.0033 0.21 12.0 0.6 1 23 852 875 852 875 0.94 16 17 5.2e-05 0.0034 17.7 1.0 1 23 881 904 881 904 0.97 17 17 0.011 0.74 10.3 0.9 5 23 917 936 908 936 0.86
Sequence Information
- Coding Sequence
- ATGTCGGAAAATTCAAAGCCAAAAACCGAAACTGAGCCTAGCTGCCTGCATTGCAGAGTGTACAATTCAAAGCAGCCGTTTCAGGAGATATTTGATGAAGTGGGAATTGAAATCGAACTGCCCAATCTGTTGGCCAaatatttccaattaaatgTGAAACCCGATccaaagaagcagcagcttctCTGCCAAGAATGCGTCAAAACATTAATACGCTTTTTCGACATCGATGAACTGCAGCGCGAACAGAATGCGGCCAATGCTATCAAGAATAAGTCGAAAAAGCAGGCGAAGGTTGACGCTGCACCAGCTGCACCACCTGCACCCGTGGCTTGCAAAAAGGAAGCGCAGTCCCCTAAAAAACAGACGCCGCCAGTGAATAAAGCTAAAAGTGAATCCAGAAAGTTGACGTCATCTGTAAAGGTGCCAGCAAAGTCCGCTGCGGTGCCGCCTGCCAAGGTATCACCTCCAGCGAAGTCAATTTCCATACGCATTACCAAAGGAAAATCAGTGACCGTAACATCGAAACGTGCCCAGGTCAAGACTAGCCCCAAACCAAGTGACAATTCAAAAGGTAAACGGGGCAGCACGAAGGAAGCTGGATCAGGCGAGCAGGAGCAGATTAGCGAGCTGTTACGTGATATACTAGATGATGAGAAGGCGCCAACCGATCAGAAATTCGCcgaggcagcggcaacagtgcGTCAACTGGAAACTCAAGTCGCTGCAGAGGAGAAACAATTGAAGCAGTCTGCTGCcgaggtggaggaggagacGGATAAGCAGCGGGAAAACGCTGATGAACTGGAGTTTCTGCTCGAGGATGACGATGTATCCTCTGGTTCGGATGAGCGTCACTTTAAGGTGGAGAAACAGACGTCACATTATAACTCACAGTCGCAAAATGAAAGCCAAAGTGAGGATGATTCTCTCAAAGTGGAACCCTTCAACTTTGTATTGATCAAGGAATCTGACGACATTGCAGATCTGCACGAATATTTGGGAACTGTGGTGAGGACTTGCTTCGATACGTTGACCTTTGAATGGGCCACCGTCTGCTGTCACTGCTCGCTGAAGTGCAGTAAATTTGAGAACTTGTTGGCGCACATGATAAAGTGCCATCAGTTGCCCGAGGAGAGTTACAAGTGTCCCATTGAGGACTGCAATACGGAGTTGCATAGCCGTAAATTCCTGGCCATGCACTTGGTTCTGTTGCACGCACCTGTGGCAGACATACCCATCTATGGCTGCTGTCCCGAGTGCAACATGACCTTCTCCAATATACTGCAGTACAATAAACACTCCTGCGCCCATGTCATCAAGAAGCGTCGTGGCATACGCTTATATTGCGAAATGTGCGGCTTGGAGTTCCCCTCATGGAAACGCTTCAATTTCCACAATCAATTCCATTTGGAGAAGCATCGACCACGCGCTTGCTTTGTGTGCGACTATGCGGATAATAACATTGATGAACTCTTccagcatttgcattattcACACGAACCCGAAGGCACACACTTCTGCGACAtCTGTGATCTGAATTTCCGTGACGCTACAATTCTTGCGGATCACAATAAAACCCATACGAATGTCACCAGCACCACATACACTTGCAACGTGTGTGACGCCAACTTTGACACACGCGGACGTCTCAATAGTCATGTGCGCATCACACACAGCTCTGCGATTAGCTGCGAGCTGTGCTGCCGGGAGTTTGCCACAGAGACCACCTACAACATACACATGAAGAAGCATCTGATCATTGAGCGTGAGGTGAATGTGTGCAGCAATTGTGGGCAACTCAGCGAGAATCATGGAAAGATGCTGAATCACGTTATGAATGAGGATTCGATTTGCTATGGCGTTGAAATCTATTTGGAAATACTTCGGGAtgcctatgtgtgtgaatattgTTCGGCGTACTTTAAGCAGAAGACGGATTTGCGTGCGCATCGGGATTCGGGTGTGCATAAGGATGGCTTATTTTGGTGTCATCCGTGTGGCAAGGAGTTTACCGAAATGAAACTATATCGTCATCATTTGCGCAActatcaacagcaactggcaGATGTTGAGCATCGCAAACTCGAGCTTTGCCTTTACTTTATGTGTGACTATGGGGATTGCTTTGAGTCGTACATCAATTGGAATTCATTGTATACACACAAGCGACGCACTCACGATATGGTCGACAAGCTGGAAGCGGCGAAGCCAAAGGTGAACGAATGGATCTGTCAGTTCTGTCAGAAAGTTTGTCCATCGAAGATGTCGCTATCGGTGCATGTGGCACGCAGTCACAACAACAATAATGTTACGTGTTCAGTGTGCAAGGCGTCGTACAAGGATGAGGAAGCACTGAAGAAGCACAACGCCTATTGGCATGAGCCGATGGAGTGTGAATTGTGCCTGAAGATCATCAAGAATCGTCGCAACTTCGACACACACATGAATGTGGTGCACTCGAATAATAAGCGTTATAGCTGCAGTGTCTGTGAGAAGGGCTTCTATCACAAGAGCGAAATGGAGTCACATAAGCGGTTGCATTCACAATCGTACAGCTGCGAACAGTGCAGCTTCGTTACAAAGAACAAGAAATCCCTGTCGGTGCATATACTTGGACAGCATTACAAACGCTACGCTTTTGAGTGTACTTCGTGCAACAAGCGCTTTGGACGTCGTCAGGGCCTTACCAATCATATCCAACGTGCCCATGGCTCGAAGCATATGTGTCGCGATTTCTTTGAGGGTGGCTGCAACAAATACTTTGCCACAACTGCACAGCTGAATATGCATGTGCGTAAGGTTCACAATGGCAGCATTTTGCTAGCCGATGCTGAAGAGGATGAGCGTCAGGAACGGGATGACGAACCGaaggaacaacagcaaataatacCCAAAATTGAGCTGCCATCAGAACCATCGCCAGCAAAGAAGCGTGGCATACGCTTCGATGATGATACACAGATCGAGTTCATTACCCCCGATCCCGAGGAGGAGAACACCGCGTATGCGGAAGACTCTGTGAAACAGCaagaaatcaaatgcaaaaccccgccaacaaagagaaagaagaaacaaTGTTAA
- Protein Sequence
- MSENSKPKTETEPSCLHCRVYNSKQPFQEIFDEVGIEIELPNLLAKYFQLNVKPDPKKQQLLCQECVKTLIRFFDIDELQREQNAANAIKNKSKKQAKVDAAPAAPPAPVACKKEAQSPKKQTPPVNKAKSESRKLTSSVKVPAKSAAVPPAKVSPPAKSISIRITKGKSVTVTSKRAQVKTSPKPSDNSKGKRGSTKEAGSGEQEQISELLRDILDDEKAPTDQKFAEAAATVRQLETQVAAEEKQLKQSAAEVEEETDKQRENADELEFLLEDDDVSSGSDERHFKVEKQTSHYNSQSQNESQSEDDSLKVEPFNFVLIKESDDIADLHEYLGTVVRTCFDTLTFEWATVCCHCSLKCSKFENLLAHMIKCHQLPEESYKCPIEDCNTELHSRKFLAMHLVLLHAPVADIPIYGCCPECNMTFSNILQYNKHSCAHVIKKRRGIRLYCEMCGLEFPSWKRFNFHNQFHLEKHRPRACFVCDYADNNIDELFQHLHYSHEPEGTHFCDICDLNFRDATILADHNKTHTNVTSTTYTCNVCDANFDTRGRLNSHVRITHSSAISCELCCREFATETTYNIHMKKHLIIEREVNVCSNCGQLSENHGKMLNHVMNEDSICYGVEIYLEILRDAYVCEYCSAYFKQKTDLRAHRDSGVHKDGLFWCHPCGKEFTEMKLYRHHLRNYQQQLADVEHRKLELCLYFMCDYGDCFESYINWNSLYTHKRRTHDMVDKLEAAKPKVNEWICQFCQKVCPSKMSLSVHVARSHNNNNVTCSVCKASYKDEEALKKHNAYWHEPMECELCLKIIKNRRNFDTHMNVVHSNNKRYSCSVCEKGFYHKSEMESHKRLHSQSYSCEQCSFVTKNKKSLSVHILGQHYKRYAFECTSCNKRFGRRQGLTNHIQRAHGSKHMCRDFFEGGCNKYFATTAQLNMHVRKVHNGSILLADAEEDERQERDDEPKEQQQIIPKIELPSEPSPAKKRGIRFDDDTQIEFITPDPEEENTAYAEDSVKQQEIKCKTPPTKRKKKQC
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00510763;
- 90% Identity
- -
- 80% Identity
- -