Basic Information

Insect: Drosophila macrospina
Gene Symbol: BCL11A
Assembly: GCA_035042075.1
Location: JAWNLW010000286.1:805979-827088[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 6 0.027 1.7 9.2 2.4 1 23 300 323 300 323 0.95

2 6 2.7e-06 0.00017 21.7 1.0 1 23 800 822 800 822 0.97

3 6 0.012 0.81 10.2 4.7 1 23 828 850 828 850 0.99

4 6 1.2e-06 7.5e-05 22.9 3.2 2 23 1130 1151 1129 1151 0.97

5 6 1.5e-05 0.00099 19.4 3.3 1 23 1157 1179 1157 1179 0.99

6 6 2.8e-05 0.0018 18.5 0.4 1 22 1187 1208 1187 1208 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	6	0.027	1.7	9.2	2.4	1	23	300	323	300	323	0.95
2	6	2.7e-06	0.00017	21.7	1.0	1	23	800	822	800	822	0.97
3	6	0.012	0.81	10.2	4.7	1	23	828	850	828	850	0.99
4	6	1.2e-06	7.5e-05	22.9	3.2	2	23	1130	1151	1129	1151	0.97
5	6	1.5e-05	0.00099	19.4	3.3	1	23	1157	1179	1157	1179	0.99
6	6	2.8e-05	0.0018	18.5	0.4	1	22	1187	1208	1187	1208	0.97

Sequence Information

Coding Sequence: atgtacaacaaaatGCTGTCGATCAGTGAGGATCATGGATTCCGTTCGCTGAGCCACTCCGACTCCACAGAGAACGATGCTGTCGCCGCACAGGACATCCTGACGTGCGGCGCCTGCCAGAAGACCTTCGCGCTGTCGGACATTGTCCGGTTCATACAGCACAAGGTGCTGCAGTGCAACAAGGAGAACTATGGACAATGCACCACACAGGCGCCGAGCATGGATCGGGATGCCGACGAGGGTCGTCCATTGAGTTTGGTGAATCGTCGTCCCTCGATATCGGCGCCAATCACAGCGGGTCGCAAATCGGCGCCAGTTGCCGGCAGTGGGTCAGCGAGTGgggccaatgccaatgcggTGGCAAGTGCCGCCGCCGCAGCGGccgcaacggcagcggcagcggcagcggcagctgcggTCGCCAACAGTGCGGCAAGTGGctcacgcatacacacaccgCCGCCAAGTCCAGCGGATTTGTTGGCCGATGGCGCCAGCAGCACACCCAAAAGATTGGTCGATGAGAATGACAATACGACGCCGAAGGCGGACAACGATGGCCTCACCTCCGGTGCAGCCTTGGCGGCAGCCAACAGTCCGCGTGCCCCATCGCAGTCGGCGCTGCCGCACATACACGACTGCGAGCTGGACGACGATGACAAGCCAAAGGTCAAGCAGGAGCCCACGTatgccgacgacgacgaagaggaacaacaactgccacagcaacaacaagtcgaGCTGGACAGcgagctgcagcaacaacagcaacaacaacaacaacaacaacagcaacaacaacagcccgCCGACGATTGCCAACAGCCGCTGGCCAAAAGGCCCAAAATGGAGCTGGTCGATGCGGAGGCCAACACGGTGCACACAGaGCCCAGCAATTATACGTGTTCGACGTGCAAGACCCGTTACACATCCGCGTGGCGCCTCATCCAGCACGTGCAGCACTCGCATGGCGTCAAGATCTACGTGGAGACGAGCGGCGGCGCCACCTTGACGGTTGCCACGCCCGCCGCCCTCAATGCtgccgccacagcagcagcgaatgCCAACCTCGGCcttggcgtcggcgtcggcctCAACGTGAACGtcagcggtggcagcagcattagCCCCAATCGCAGCCTcagcccaacagcagcagcagctgcagcggcggcagcggcagctgtcGGTGTCCCGCTGCCGTTGCACGCTCTCATGGCGCAGGCGGTTGCCTCGCAGTCGGCGGCGCAGTCGCCGGCAGgcaagcgcagcagcagcagcagcaacagccacagcaacagcaacagcaacaacagcatcagcagcagcagcaacaacaactcagtTGGAGCGGCAGCAGTGGCCAAcacgagcagcaacagcaacaacagcagcagcagcagcagcaacgtcagCAGCGGCAACTCGCCCACACAGCAattgctgcagcaacagcagcgtgtgcagcagcagcagcaacaacagcagcaacagcagcagcagcagcagcagcagcagaacatGGCCTCGGCAATGGCAGCAGGAATGCGTCATCATCCACTGCTGGCGCCTCCAGAGGCAATGCACGCGAATCCGTTTCAGTTGCTGCGGATGCCGTTGCCGCCGGCGTTGGCCCAGAGCAATGTAGTTCCTAGCGTGTCGCCGCTCTTCGGAAGGCCCACGCCCGCTGATCACTATCGCATGGAGCAGCTGGTGAGCGAGCAGTTTCGTCATCATGGCTTCAACTtggccgccgccgccgctgccgctcaGGCGCAGTTCAATgccagcaaccagcagcagcagcagcagcagcaacagcagcagcaacagcagcagcagccaggtCAAGGTGTTGTCGTCAATGTTCCTAATCCCGTCGAGCAGCGTCCGCCgtcgagcaacagcagccaacgtGGCTCTGTGCCGCCCGCCTCCTTGCCGCCGCCATCGCTCAgctcccagcagcagcagcagcaacagcagcagcagcagcaacaacagcagcagcaacagcagcagctacaacagcagcaacagcaaccgatTGCCGCTGCTGTGAGTCCTGCGTCGGTCAGTTTGGAACCGCAGCAGATGGATTTTTACTCGCAGCGATTGCGTCAGCTTGCGGGCACAACAAGCCCTGGAGCTGGCAACATTGTTAACTCGAGCTCGCCGAGTCCACGACAGAAGCAATCGCCGCGTTTCGCGAGCCCCTCGCCCAGCGCCGTGACCCCCACGCCGCGTCCCCATTCCTTGACGCCGCCGGAGAAGAGCGCCGCCTCCGAGAACGGTGCCGGCAACCTAACCCACTCGACCACGCCCCGCTCGGCCAGCACACCGCCCACCAAGGCGACCCTCAATGCCACGGATGCGGAGCTGCTCGAGGCGAACTGCTTTGCGTGCGGCTATTGCGACAAGAAGTTCAGGTTTGAGAACAATCTGATCATTCACCAGAGGACGCACACGGGAGAGAAGCCGTACAAGTGCACCGCCTGTGACTTCGAGTGCTCGCACATCCAGAAGCTGATGAAGCACATGCGCGTCCATCGCAGTCCGGCCGAGGGACAggacggcagcagcagcaacggggGTGATAACAATCAGGATGGCCACGATGGCGGCAGCAATGCCGACTCATTGGAAACGAACGAGGCGGACAACGATGATGATCCCAATCCGGATGAGTCCGACGAGGAGCTCAATGATGAGGATGccgatgcggatgcggatgcggatgccgAGGGcgaggacgacgacgaggatgaGCTGGAGGACTGCGAGGATGTTGACTATGAGGCCGAAGATCTCAGTGTCAACAATCGCATCGATGGCAAGAGCCAAAGCCCCAAGACGACCAGCTCGGGTGCCACCTCGCTGGTGGGTGAGCTGATGGACAAGTTCGGGCTGTCCAACATTGCCCAGTACTCCGAGGCCTACAAGCAGGCGCTGCAGGAGTCCGGACGCAAGGAGGCAGCCGccgtggcagcggcagcggctgctgctgccgccgtcgacaacaacaatcgtgGCTCCGTGTCGgccggtggtgctggtggtgcccAACCGCAGCCACTGTCGGACAAGCTGAACGGGCTGCCGGTGGCAGCGCTGCGATTGCGGGATGAGTTCGCCAAGAACTGCAACATGTtccagccgcagccgcaggaTGCGCCCGCCCAGGTGCCGCTCTTCAATCCCTTCCCCAATCCCTTCGAGCTGTCCAAGCGCATGAAAATCGACAGTGGCGACTGGTGGGGCATGTCCGCCCTGCACCGCAACGAGGCGCTGTTCGAGAACCTCAAGCTGAAGCCGCTCGGCCTGGGAGGCGCCAACTCGCTGCTGCAGGGACCTCTGCTGAAGAAGGAGAGCCGGCAGCGCAACGACACCTGCGAGTTCTGCGGCAAGGTCTTCAAGAACTGCTCCAACCTGACCGTGCACCGTCGCAGCCACACCGGCGAGAAGCCGTACAAGTGCGAGCTGTGCTCCTACGCCTGCGCCCAGAGCTCCAAGCTCACCCGCCACATGAAGACGCACGGACGCACCGGCAAGGATGTCTATCGCTGCCGCTTCTGTGACATGCCCTTCAGTGTCCCCTCCACGCTCGAGAAGCACATGCGCAAGTGCGTCGTCAACCAGGGCAAGGCTGCCGCCGCGGCCGCCAATGCAGCCAACGCCGTTGCTGCCGCCcaagctgccgctgccgcccaGCAGTTGCAAGCCGCCGCCCaggcccaacagcagcagcagcagcagcaacagcagcagcagcaacagttgccctCGCAGTCGCAGCTATCGCCCGCCTGCCCCATGGGCGtcggcgtgggcgtggccgtcGGCTACCCGCCCCAATTCGGACACAACCTATCGCTGCCGGGCAGCGTGAGCGGGGACAACGATTCAAATGCTTCTTCCAGCCTGCCAGCGCACTCCATCTCGCTGAAGGAGGAGGCATGA
Protein Sequence: MYNKMLSISEDHGFRSLSHSDSTENDAVAAQDILTCGACQKTFALSDIVRFIQHKVLQCNKENYGQCTTQAPSMDRDADEGRPLSLVNRRPSISAPITAGRKSAPVAGSGSASGANANAVASAAAAAAATAAAAAAAAAVANSAASGSRIHTPPPSPADLLADGASSTPKRLVDENDNTTPKADNDGLTSGAALAAANSPRAPSQSALPHIHDCELDDDDKPKVKQEPTYADDDEEEQQLPQQQQVELDSELQQQQQQQQQQQQQQQQPADDCQQPLAKRPKMELVDAEANTVHTEPSNYTCSTCKTRYTSAWRLIQHVQHSHGVKIYVETSGGATLTVATPAALNAAATAAANANLGLGVGVGLNVNVSGGSSISPNRSLSPTAAAAAAAAAAAVGVPLPLHALMAQAVASQSAAQSPAGKRSSSSSNSHSNSNSNNSISSSSNNNSVGAAAVANTSSNSNNSSSSSSNVSSGNSPTQQLLQQQQRVQQQQQQQQQQQQQQQQQQNMASAMAAGMRHHPLLAPPEAMHANPFQLLRMPLPPALAQSNVVPSVSPLFGRPTPADHYRMEQLVSEQFRHHGFNLAAAAAAAQAQFNASNQQQQQQQQQQQQQQQQPGQGVVVNVPNPVEQRPPSSNSSQRGSVPPASLPPPSLSSQQQQQQQQQQQQQQQQQQQQLQQQQQQPIAAAVSPASVSLEPQQMDFYSQRLRQLAGTTSPGAGNIVNSSSPSPRQKQSPRFASPSPSAVTPTPRPHSLTPPEKSAASENGAGNLTHSTTPRSASTPPTKATLNATDAELLEANCFACGYCDKKFRFENNLIIHQRTHTGEKPYKCTACDFECSHIQKLMKHMRVHRSPAEGQDGSSSNGGDNNQDGHDGGSNADSLETNEADNDDDPNPDESDEELNDEDADADADADAEGEDDDEDELEDCEDVDYEAEDLSVNNRIDGKSQSPKTTSSGATSLVGELMDKFGLSNIAQYSEAYKQALQESGRKEAAAVAAAAAAAAAVDNNNRGSVSAGGAGGAQPQPLSDKLNGLPVAALRLRDEFAKNCNMFQPQPQDAPAQVPLFNPFPNPFELSKRMKIDSGDWWGMSALHRNEALFENLKLKPLGLGGANSLLQGPLLKKESRQRNDTCEFCGKVFKNCSNLTVHRRSHTGEKPYKCELCSYACAQSSKLTRHMKTHGRTGKDVYRCRFCDMPFSVPSTLEKHMRKCVVNQGKAAAAAANAANAVAAAQAAAAAQQLQAAAQAQQQQQQQQQQQQQQLPSQSQLSPACPMGVGVGVAVGYPPQFGHNLSLPGSVSGDNDSNASSSLPAHSISLKEEA

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00519433;
90% Identity: -
80% Identity: -