Dmac014995.1
Basic Information
- Insect
- Drosophila macrospina
- Gene Symbol
- grau
- Assembly
- GCA_035042075.1
- Location
- JAWNLW010000593.1:3969222-3971312[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 9 0.025 1.6 9.2 1.1 6 23 297 314 297 314 0.98 2 9 5.4e-05 0.0035 17.6 2.9 1 23 320 343 320 343 0.93 3 9 0.00017 0.011 16.1 2.3 1 23 351 373 351 373 0.97 4 9 0.00032 0.021 15.2 0.5 2 23 379 401 378 401 0.96 5 9 0.1 6.6 7.3 0.1 2 23 407 428 406 428 0.95 6 9 2.8 1.8e+02 2.8 3.8 2 23 437 458 436 458 0.90 7 9 0.0001 0.0065 16.8 0.2 2 23 466 488 465 488 0.96 8 9 2e-05 0.0013 19.0 0.4 3 23 496 516 495 516 0.98 9 9 0.00065 0.042 14.2 8.5 1 23 522 545 522 545 0.98
Sequence Information
- Coding Sequence
- ATGATTTGCCGTCTGTGCCTAAACAGTGCCAACGACACCATCCAAATATTTGAGGGCGTTGGCGTGTCCCTAAACGTTGCCACGGTGCTGGCTCAATATTTTTGGTTCCAGCCGAAAAACGATGATCCAATATCCACGGCCATCTGTGTGGCTTGCTGGACACGCGTTAGTGACTTTCACGAGTTCTATTGTAGCGTGGAAAAGGCGCATCGTCTGCTCACCGAACGATTCTCGTTGAAAGGTGGcgagcagcaggagaagatTAATAGCAGCGTAGGAAGTACACAGGCAGGTGCACAGAAGCAAGAGCAGTCTGAGGATTCCAAGGAGTTCCTTGATAACAGCGAGCGTGAtagcgatggcgatggcgttgACGATGCTGACTTGGATCAGGACAATGATAATGCTATCGAAGCTTTATATGCCAGCGAAAGCGAAGCAGCTGCATCATTTAGCAATGAGCAGTTTCTCAACGATGTGCTGGCCCAGCAAGAGGCTGGCGAACCTATTGCAGGGACTGAGCCGGAGCAGGTGATTGTTAAGCAGGAAATCGGAATTGTGGATGTGCAGGAGCGCCGTGAGACACGCGCCACACGTGCTAAAAGCAAAGCGATTCAATTGCTCGCCAGTGAATCACCGCCAGCCGAAAAGTCTACGCCCGCTAAGCGCAGGGGCAGATCAAAGTCTGAGAAAGTCGACGCGAATGTAGAGGATGGAACGAAGAACAAACGTTATGTGGATTATAAGAAATCCATGTGGGAGATTGACAAGAAGATAGCGCAGCATATGCGCCTCACCTGCAGCATTTGCCATGAGGGACAAGAGACGTTTCTATTGCTGTGCAAGCACATGCAGCAGGTGCATCATCGCAAGGGCTACGCGGTCTGCTGCAACAAGAAGTTCTACAAACGCTCCTTTCTCACCGACCACATCGATCGTCATTCCAATCCCGAGAAATTTAAATGCAATCTCTGTGGCAGAACCTTTGCGGACAAGCAGTGTCTGCGCAATCATGAGCTGCTGAAGCATCAGCCCGACGAGGAGAAGACCTTCATGTGTGAGCACTGTCCCAAGCGATATACGAAGCAGTATTTGTTGGATCAGCATAGGATTATACACAAGGAGCGCACAGTGCCCTGCGATCTCTGTGACAGGCGGTTTCCCAACGATTCGATGCTCTGCACGCATGTGAAAATGGTGCATGGCAATTATGGCACAATGTGCGATATTTGCGCACAGGTGATAAGGGGACAGGCTGCCTTTCAGCGCCATCAGTTGGAGCACGCTGGCATCACGGAGCCCAAGGTGCAGTGCGACATATGCGGATCGTGGCACAAGAACAAATATAGCCTGAAGAAGCATGTGAGTCGACACAATGGCTCCTCGGAGGAGAGCACCTGCAACATTTGCGGCAAGGTGTCGCCCAATCGCAGCGCCATGTTAAGCCATCAGCGTTATGTGCACACTGCGGATCGTGTACATGGCTGCAGTGTGTGCAACAAGAAGTTCAAAAAGGCCATCAACCTCAAGGAGCACATGGCCATCCATACGGGCGAAGTGCTATACAAGTGCCCACATTGCCCCAAGACCTTCAACTCCAATGCCAATCAGCATTCGCATCGCAAAAAGTGTCATCCCAAGGAGTTCGAAGAGGCGCGTAAGGCGCGACTACAGAATCGCATGGCGCCCAGTGCGAGTGAAAGCAAGGCCAAGGCAAGCATGATTACGATAACGACATCGGGGGAAACGGATGGCGAATTGGAGACGCATAACATTCTGGTGACGACGACGGAGCAGAGCGATGACgagctggaggaggaggacgaggAGGAATTCAAAGGCGAGGACATTGAGTTTATGCTCACGCTCAGTCCACAGCCAACGGAATAG
- Protein Sequence
- MICRLCLNSANDTIQIFEGVGVSLNVATVLAQYFWFQPKNDDPISTAICVACWTRVSDFHEFYCSVEKAHRLLTERFSLKGGEQQEKINSSVGSTQAGAQKQEQSEDSKEFLDNSERDSDGDGVDDADLDQDNDNAIEALYASESEAAASFSNEQFLNDVLAQQEAGEPIAGTEPEQVIVKQEIGIVDVQERRETRATRAKSKAIQLLASESPPAEKSTPAKRRGRSKSEKVDANVEDGTKNKRYVDYKKSMWEIDKKIAQHMRLTCSICHEGQETFLLLCKHMQQVHHRKGYAVCCNKKFYKRSFLTDHIDRHSNPEKFKCNLCGRTFADKQCLRNHELLKHQPDEEKTFMCEHCPKRYTKQYLLDQHRIIHKERTVPCDLCDRRFPNDSMLCTHVKMVHGNYGTMCDICAQVIRGQAAFQRHQLEHAGITEPKVQCDICGSWHKNKYSLKKHVSRHNGSSEESTCNICGKVSPNRSAMLSHQRYVHTADRVHGCSVCNKKFKKAINLKEHMAIHTGEVLYKCPHCPKTFNSNANQHSHRKKCHPKEFEEARKARLQNRMAPSASESKAKASMITITTSGETDGELETHNILVTTTEQSDDELEEEDEEEFKGEDIEFMLTLSPQPTE
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00602095;
- 90% Identity
- iTF_00510776;
- 80% Identity
- -