Dmac011044.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Drosophila macrospina
Gene Symbol
RREB1
Assembly
GCA_035042075.1
Location
JAWNLW010000527.1:769545-776548[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 13 0.037 2.4 8.7 0.8 1 21 258 278 258 280 0.93
2 13 0.00034 0.022 15.1 0.2 1 23 290 312 290 312 0.98
3 13 8.3e-05 0.0054 17.1 7.3 1 23 318 340 318 340 0.98
4 13 0.77 50 4.6 2.1 2 20 551 569 551 571 0.93
5 13 0.037 2.4 8.7 0.1 1 23 739 761 739 761 0.97
6 13 1.3e-05 0.00082 19.6 0.7 1 23 771 793 771 793 0.99
7 13 0.00085 0.055 13.9 2.0 1 23 799 822 799 822 0.97
8 13 0.003 0.2 12.1 2.0 1 23 1118 1141 1118 1141 0.95
9 13 8.9e-05 0.0058 17.0 0.3 2 23 1504 1525 1503 1525 0.97
10 13 0.15 9.7 6.8 6.3 1 23 1531 1554 1531 1554 0.97
11 13 4.6 3e+02 2.1 3.6 1 23 1700 1723 1700 1723 0.79
12 13 0.0086 0.56 10.7 0.5 3 23 1784 1804 1782 1804 0.96
13 13 0.0014 0.093 13.2 4.8 1 23 1810 1832 1810 1832 0.99

Sequence Information

Coding Sequence
ATGctggcaacacaacaacaacaacaaccacaacacacaacaacaactgttgctgctgctgtggaaacaacaacagcaacaacaacatcatcagttGCACACAACAGCGATGCCAGCGACATGGAGCGCCAGCGTCGTGATTCAACCACCTCAGAGTCCTCGCTGGAGCATCTCGACTTGGGACGCACACCAAAGaagctcagcagcagcagcggtgcGCCGCagccgacgtcgacgccgcacgaaacgacaacgacgactgTGACGTCGCGTAAGCGTAAACTGCGACAGCAGCaatcccaacaacaacagcacacgctctccgatgaggatgatgagcagcaacagcagcagcagcagcagcagcaacaacaacagcagcagcagctagatCAGTCAACGCAGCGACCGCGTCACAAGCAGCGACGCAGCGTGAACGCAGCCAGCGCCAGCATCGTTGTCGATTATAGCGCCAGCGGTGACGCCAGTTCGCTGCGCAAAAAGTTTCGTTTGAATCGCAGCGTTGGCAGCGGTATTAACGGTGATCTCTCCGAGTCGGGCTTCGTTGATGGCAGCGCGCATAGCGGTTATTtgctaagcagcagcagcgccgtGAGCAGCGCTCCGTCGGCCTCGGCGTCGACAGCGGCCGCAACAGTCGCTGTTGCGTCGCAGCAGGCGTCATCGAGCAGCTCGGGCGGCTCATCGCCGCACGGTTTGTGCCTATCCAGCGCCGAGTCGGGCATTGGCGCCGGCGATGATCACATGAAATATCTGTGCCCCATCTGTGAGGTTGTCTCGGCCACGCCCCATGAGTTCACCAATCACATACGTTGCCACAATTACGCCAACGGCGACACTGAGAATTTCACCTGCCGCATTTGCTCGAAGGTGCTGTCCTCTGCCTCTTCGCTGGACAGGCACGTGCTGGTGCACACAGGCGAGCGGCCCTTCAACTGCCGTTACTGCCATTTGACATTCACAACGAACGGCAACATGCATCGCCACATGCGAACACACAAACAGCATCAggcaacgcagcagcagcagcagtcgcagtcgcactcgcagtcgcaatcgcagtcgcagcactcgtcgcagtcgcagtcgcagcagcgacgtcagcagcaggcggcggcagcagtcGCCACGCAGCTGGCAGCGGGCAGATCGGAGAGCTATGAGAGCGATGCGAGTTGCTCGACGGATGTGTCGAGTGCACAgagtcacagcagcagcagcaatcactccagcagcaacaacaacaacaacaacaacaacaagctcagcaacaacaacaacaacaataataataataacaacaacaacaacactgagaATTGCCTCAAGCAGCGTCGCCACAAGAcgaacatcaacaacaacaacatactgGCCAAAGAGGAGCAACTGGAGCTGCTGGACGAGCCGGAGGAGCTGCCCTCCGATGTGGACAGCATGGAGGAGCATGTCGCTCAGCTGATCACCTCCACGCCcgatgtggcaacgctgctcgCCTCCGGGGGCAGCACACCGAGTGAATCGCCGGCGCCACCGCTGCTGCTCAGTTGTCCGGTGTGCACGGCGGATGAGTTTGAATCGCTGGCAGCATTGTGCCAGCATCTGGATGCCCAGCATGCGGATATACCCGCCAAGTGTCGCGAATGCGAGGTAATCTTTGCCACGCAtcggcagttgcagttgcacagcTGTCGTGGCATGCagatgttgccgctgcttggCGCCAGCTCGAGTCCCATACACAAGCTGGAGCAGCCGGAGCACGAGGAGGAGCacgagcaggaggaggaggagcacgACGatgagcaggaggaggaggagcaagaggaggaggatgatTTGGATATGGACatggagcagcaggaggaacAACAGCCGACGGAGCAAGCCGAACGCGATGACTTCTTTCAGCAGCTCTACCTGAAGGGCAAGGCGCGCCACAACATCAGCGTCCCGCTGCCCTCGCCGATCAAGCACGAGGTAACGGATCGGGGGGACAGTCGCCAGGATCTGGCGGACATCCAGAGCATACTGAACATgaccagctccagctgcacaTCCAGTTTCCTGCGCAACTTTGAGCAATCGGTGAACACACCCTGCTCCAGCCAATACAGTCTCGATGGCCGCGACGGCGATGAGGAGGCCCAGGATGCCTTCACCAGCGAATTCCGACGCATGAAACTCCGCGGCGAATTCCCCTGCAAACTCTGCGTCGCCGTCTTTCCCAATCTGCGCGCGCTCAAGGGTCACAATCGGGTGCATCTTGCAGCCGTCGGTCCAGCCGGCCCCTTCCGCTGCAACATGTGTCCCTATGCCGTCTGCGATAAGGCGGCGCTGGTGCGGCACATGCGCACCCACAACGGCGATCGGCCGTATGAATGCGCCGTCTGCAACTATGCGTTCACCACGAAGGCGAATTGTGAGCGACATCTGAGGAATCGGCATGGGAAGACCAGTCGGGAGGAGGTGAAGCGTGCCATTGTCTATCATCCGGCCGAGGATGCCAGCTGTGAGGAGTCCAAGGCCACGACTGCACGGCTGCACGACACGGATCTCGGCGAGCTCAGCTATCGCTCCGTGTCGCCGGCACTGAGCAGTGCGCCGGAGACGTCGTCCCAGCTGAAGCACATGTTGCTGGCGGAGCCAACAGTTGCTCCTggtgtggcaacaactgttgctggtgcGGGTGCGGTTGCGGGTGCGGGTGCTGGGGCGGCTGCTGTGAAGGTTGCGCCACTGAAGATACAGGTGAAGAGTCTGGATCAGCTGGTGGACAAACAGCTGGCGCCGGCCTTGGATCTCAGCATGGATGTGTTGGATCTCAGCAAGAAGCCGACGGCGGCGCAGGAgctgcaggagcagcagcgggagcagcagcgtgagcagcgggagcgggagcatGAGTTGCTGctcgcccagcagcagcagcagcagcaacaggtgcaacagcagcaacagcagcagcagcagcagcagctctttGGTGCCGGCGATGCTGCCACACAGTACATGCAACAGTTGTTCCGCAATCTCATGTTTCAACAGACCACAGCGGCATTCCCCTTCTTCGGCTTCATGCCACCAACCACAGCAGGCGCAGCAGCCACAGTTGCCGCCGACAAATgcacagcggcagcggcagcaacaacaagcgccacaacgccagcaacaacacttgccacATCCGCCACCATGGGTCTGCCACTGCCCCTGCCTGGCTCACTGGGCGTCGGCGTTCCGGTGCCCGCCGCCGGTCCCGTCAAGATGGTCATCAAGAATGGCGTGCTGATGcccaagcagaagcagcgtCGCTACCGCACCGAGCGACCCTTTGCCTGTGAGCATTGCTCCGCCCGGTTCACGTTGCGCTCCAACATGGAGCGTCATGTGAAGCAACAGCATCCGCAGTTCTATGCGCAGCGTCAGCGCAGTGGACACCATGTGATGCGCGGACGTGCTGCATCCTCCTCAAccgctgcagcggcagcggcagcagcagcagcagcggcggcggcagcagcagcggccatGTCCAATCtcagtcagcagcagcatggaCATCATGCGCATCATGCGCACATCTCCGATCAGGTGAAGTACGCCATACTGGCGCAGCAGCTGAAGGCGCGCAAGGATACGGATCTGCTGCAGCAGGCCTTGGCCCACGGCTCCAGCAGTGTGGCCGGCAATCCGCTGCTGCACTTTGGCTACAAACATGGCCTgaacaatggcaatgggagtgggagtggaaGTGGCAATGGGAGTGGcaatggaagtggaagtggaagtggtcAGGCCGctgttaatgatgatgatgagccgCCGAAGTTGATCATTGATGAGGATGACGAGGACgtcgaggaggaggaggagggttTGGACGATGAGctggatgaggaggaggatgaaCTCATGGAGGAGGAACTGCTGGAGTCCGAGCAGCTAACTGAGCCGCAGccagagcagcagcggcagccagCACGCAGCTCCACGCCCATTGAGCGTGAGCGTGAGGCGGCCAAAAAGGTGGCGGAGACCATCCTGGAGCAGGCCATCAAGGCCGGCAAGGTCGTGGACAGTGCTGACAGCGTGCTGGACACCAAGAAGTTGCCACAGAAATCCCCGAGTCCCAGTGCAACGGCCGCAACCAGCGCCACAACGGCCACGACAATGAAGACGATGATTGCCCAAGCGGAATCGGTGGCAAAGTCACTGAAGGAAGTGGCCAGCTCGCCGTTCAAAGATGAATCTCAGGATCTGGTGCCCGTGGCGAAGCTGGTGGATAATGCGACCAGCAATCAGGTGTCGTTCAACAGCTACTTTCGTCCGAGCGATGTGGCCAATCACATGGAGCAATCGGATGAGGAGGGACTGGTTGCCTCCGGCAGCGCCAGCGAGAGCAACAACTCCGGCACCGAGGATgtgaccagcagcagctgcaatgagCCCAAAAAGAAGTCCGCCTACAGCTTGGCCCCCAATCGCGTCAGCTGCCCCTACTGCCAGCGCATGTTCCCCTGGAGCAGCAGCCTGCGGCGCCACATCCTAACCCACACCGGGCAGAAACCCTTCAAGTGCTCCCATTGCCCGCTGCTGTTCACCACGAAGAGCAATTGTGATCGGCATTTGTTGCGCAAGCATGGGAATGTGGAGAGCGCGATGTCCGTGTATGTGCCCACCGAGGATGTGAGCGAGCCGATACCGGTGCCCAAGTCGGTGGAGGAGATCGAGCTGGAGGAGCAGCGACGCCGCAAGGCCGAGCAGCtggagagagagcgcgagaagGAGCGCGAGCGGGAACGGGAGAGGGAGCGTGAAAGGGAGCGTGAGCGCGAGCGGGAAATGGAGCTGCTTAGGGAACTGGAGCGGGAGGAGGAGAGGGAGCGCGAGCGCAGGCTGGAGCGGGAGCGTGAAcgtgagcagcagcagcagcagcaacagcagctcatcCAACAacttgcggctgctgcacaaatggttgccgctgccgccagcgccagcgccagcgccaatGCGTCGTCCCCCGTCGCAGCAGCAAGTCCCCCCGGCAGCGAGTCGCAGGGCAGCGATCTACCCTACAAGTGTCATCTGTGTGAATATTCGTTCGGCGAGCGTCTGCAGTGCTTGGAGCACATTAAGCAGCAGCATGCCCATGAGTTTGCCCTGCTGCTGGCCAAGGGAGCCATCGAGCAGGAGGAGCAATCATTTCCagcgccaccgccaccaccaccaacagcagcagccacaacaacaaccgcctCCGATGAGGAAGCTGGTTTGACATCGCGTGCCGTCAAGTATCCCGATTACAGCAATCGGAAAGTGATCTGTGCCTTCTGCGTGCGTCGCTTCTGGTCCACCGAGGATCTGCGTCGCCATATGCGCACCCATTCGGGGGAGCGGCTGTTCCAGTGCGACATCTGCTTGCGCAAGTTCACGCTGAAGCACAGCATGCTGCGGCACATGAAGAAGCACAGCGGACGCAGTCACAATGGCGAGTTGGGGGGACAATCCGATTGCTCGGACGATGAGCAGTCGGCGACGCCGCCCACAACACCCACGCCAATGATAATGCCacaagcgaacaacaacaacaacaacaataacaataacaacaacaacaacaacacttgccacaacaacaacaacagcaagcaaagcATGCGCTTGCCCAAGCTGCATGAGCTGCTGGACAAGGCGAACGAATGGCGCGTCAGTCGCCTGGGTGAGCACAAGGAGAACATTGCCGAGTCCGCCACACCGACGTcggccacagcagcagcagcagcagccgctggtgccgctgccgcagcagctgtggcaagtggcgaTCTAATTGGCAATTTGCTGGGCATCAGCGATCAGGGTATACTCAACAAGCTGCTCTCCTCGGCGGATGAGGCAGCTAAGCTGCTGGGCGTGGACAAgtaa
Protein Sequence
MLATQQQQQPQHTTTTVAAAVETTTATTTSSVAHNSDASDMERQRRDSTTSESSLEHLDLGRTPKKLSSSSGAPQPTSTPHETTTTTVTSRKRKLRQQQSQQQQHTLSDEDDEQQQQQQQQQQQQQQQQLDQSTQRPRHKQRRSVNAASASIVVDYSASGDASSLRKKFRLNRSVGSGINGDLSESGFVDGSAHSGYLLSSSSAVSSAPSASASTAAATVAVASQQASSSSSGGSSPHGLCLSSAESGIGAGDDHMKYLCPICEVVSATPHEFTNHIRCHNYANGDTENFTCRICSKVLSSASSLDRHVLVHTGERPFNCRYCHLTFTTNGNMHRHMRTHKQHQATQQQQQSQSHSQSQSQSQHSSQSQSQQRRQQQAAAAVATQLAAGRSESYESDASCSTDVSSAQSHSSSSNHSSSNNNNNNNNKLSNNNNNNNNNNNNNNTENCLKQRRHKTNINNNNILAKEEQLELLDEPEELPSDVDSMEEHVAQLITSTPDVATLLASGGSTPSESPAPPLLLSCPVCTADEFESLAALCQHLDAQHADIPAKCRECEVIFATHRQLQLHSCRGMQMLPLLGASSSPIHKLEQPEHEEEHEQEEEEHDDEQEEEEQEEEDDLDMDMEQQEEQQPTEQAERDDFFQQLYLKGKARHNISVPLPSPIKHEVTDRGDSRQDLADIQSILNMTSSSCTSSFLRNFEQSVNTPCSSQYSLDGRDGDEEAQDAFTSEFRRMKLRGEFPCKLCVAVFPNLRALKGHNRVHLAAVGPAGPFRCNMCPYAVCDKAALVRHMRTHNGDRPYECAVCNYAFTTKANCERHLRNRHGKTSREEVKRAIVYHPAEDASCEESKATTARLHDTDLGELSYRSVSPALSSAPETSSQLKHMLLAEPTVAPGVATTVAGAGAVAGAGAGAAAVKVAPLKIQVKSLDQLVDKQLAPALDLSMDVLDLSKKPTAAQELQEQQREQQREQREREHELLLAQQQQQQQQVQQQQQQQQQQQLFGAGDAATQYMQQLFRNLMFQQTTAAFPFFGFMPPTTAGAAATVAADKCTAAAAATTSATTPATTLATSATMGLPLPLPGSLGVGVPVPAAGPVKMVIKNGVLMPKQKQRRYRTERPFACEHCSARFTLRSNMERHVKQQHPQFYAQRQRSGHHVMRGRAASSSTAAAAAAAAAAAAAAAAAAMSNLSQQQHGHHAHHAHISDQVKYAILAQQLKARKDTDLLQQALAHGSSSVAGNPLLHFGYKHGLNNGNGSGSGSGNGSGNGSGSGSGQAAVNDDDEPPKLIIDEDDEDVEEEEEGLDDELDEEEDELMEEELLESEQLTEPQPEQQRQPARSSTPIEREREAAKKVAETILEQAIKAGKVVDSADSVLDTKKLPQKSPSPSATAATSATTATTMKTMIAQAESVAKSLKEVASSPFKDESQDLVPVAKLVDNATSNQVSFNSYFRPSDVANHMEQSDEEGLVASGSASESNNSGTEDVTSSSCNEPKKKSAYSLAPNRVSCPYCQRMFPWSSSLRRHILTHTGQKPFKCSHCPLLFTTKSNCDRHLLRKHGNVESAMSVYVPTEDVSEPIPVPKSVEEIELEEQRRRKAEQLEREREKEREREREREREREREREREMELLRELEREEERERERRLEREREREQQQQQQQQLIQQLAAAAQMVAAAASASASANASSPVAAASPPGSESQGSDLPYKCHLCEYSFGERLQCLEHIKQQHAHEFALLLAKGAIEQEEQSFPAPPPPPPTAAATTTTASDEEAGLTSRAVKYPDYSNRKVICAFCVRRFWSTEDLRRHMRTHSGERLFQCDICLRKFTLKHSMLRHMKKHSGRSHNGELGGQSDCSDDEQSATPPTTPTPMIMPQANNNNNNNNNNNNNNNTCHNNNNSKQSMRLPKLHELLDKANEWRVSRLGEHKENIAESATPTSATAAAAAAAGAAAAAAVASGDLIGNLLGISDQGILNKLLSSADEAAKLLGVDK

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
-