Basic Information

Insect: Drosophila macrospina
Gene Symbol: ken1
Assembly: GCA_035042075.1
Location: JAWNLW010000140.1:678153-680390[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 12 0.038 2.5 8.7 4.1 2 23 232 253 231 253 0.96

2 12 6.8e-05 0.0044 17.3 1.1 1 23 259 284 259 284 0.95

3 12 0.00049 0.032 14.6 0.4 3 23 293 316 291 316 0.93

4 12 0.00026 0.017 15.5 4.1 1 23 326 348 326 348 0.97

5 12 0.0002 0.013 15.8 1.8 2 23 356 377 355 377 0.96

6 12 0.0067 0.44 11.0 0.5 1 23 383 405 383 405 0.97

7 12 0.049 3.2 8.3 2.6 1 23 411 434 411 434 0.97

8 12 0.018 1.2 9.7 4.1 1 23 440 462 440 462 0.95

9 12 0.02 1.3 9.6 2.6 2 23 469 490 468 490 0.95

10 12 0.00016 0.01 16.1 0.8 1 23 572 595 572 595 0.96

11 12 0.0075 0.49 10.9 2.9 1 23 601 623 601 623 0.96

12 12 6.6e-05 0.0043 17.4 5.0 3 23 631 651 629 651 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	12	0.038	2.5	8.7	4.1	2	23	232	253	231	253	0.96
2	12	6.8e-05	0.0044	17.3	1.1	1	23	259	284	259	284	0.95
3	12	0.00049	0.032	14.6	0.4	3	23	293	316	291	316	0.93
4	12	0.00026	0.017	15.5	4.1	1	23	326	348	326	348	0.97
5	12	0.0002	0.013	15.8	1.8	2	23	356	377	355	377	0.96
6	12	0.0067	0.44	11.0	0.5	1	23	383	405	383	405	0.97
7	12	0.049	3.2	8.3	2.6	1	23	411	434	411	434	0.97
8	12	0.018	1.2	9.7	4.1	1	23	440	462	440	462	0.95
9	12	0.02	1.3	9.6	2.6	2	23	469	490	468	490	0.95
10	12	0.00016	0.01	16.1	0.8	1	23	572	595	572	595	0.96
11	12	0.0075	0.49	10.9	2.9	1	23	601	623	601	623	0.96
12	12	6.6e-05	0.0043	17.4	5.0	3	23	631	651	629	651	0.97

Sequence Information

Coding Sequence: ATGAATGAGGAGACTACAGTCTCAATAAATACCGTATGCCGCACTTGTTTGTCCAACTTGCAACATGATGAAGTCTACGACCTGTTTGTGGTTCCCGGCCTGGCCAagaaattgtgtgtgtgcacgtcCCTCTCAGTGGAGCACCAGGATGGTTACCCAAAAAACCTCTGCACCACCTGCTACAGCCGCCTTAACGATTTGCATGACTTTCAGAAGCAATGCGTGGACTCTGTGCAAAGGTTCAAGGAGTTGCTGGTCAACAATCATTTTACAATTCAGACAAATCCGGTGGACAACTTTGATATGCTGAATGTTGCTCCGCAGGATCTTGAGTTGCCTGATCCTCTGCTGAACagcaaaatagaaattgagAATGAGCAGGATGTTTTTAAGATGCTAGAAGATGTCGATAAAGAAACAGCAGAAgtagagaaagaggaagatctggacaatgaaattgaaagcgacaatgataatgatgatatgGACTTCCAAGCGAATAGCAGTGATTCCGATGATGAGATGCCGCTCTCACGCTTACGTAGCAATACCAGAACAACAAAGGCCGGCAGCAAAAAGAGTGATAAAGCGGAGGAATTCTCCGACtcggatgacgatgatgaagataaagatacaatAAAACCGAATCGCAAGCGAATTCCAGCAGCAGAGCGTCATTTGCATCGCATCATTGAATGCCACATTTGTCGTCAGAAGTTCAAGAAAGCAATTCGCTACGAGGAGCATATGAAACACCATAATGATCAGTTGCCATTTCAGTGCTCAGTAGAAATCTGTAAGAAGGGCTTTACCACTGCAGCAGGACTGCGTCATCATATGGACCACGCACACACGGAACTCTGCGAACTTATTCCCTGTACGGTCGAAGGTTGCGACGAATCATTCCCACGAACACGCATGCTCACACATCATCTAAAGAAGGTTCATAGCATTTTGAAGCCTGAAGTCCGTGATCATCCATGTACGGAATGCGATAAAGTATTCCGTTGTCCGACGGCGCTCAAGAAACACATGTATAAACACACTGGCGAGGAGCCACCAATTTCTTGTAACATCTGCAACAAACGCTTTCACATAAACAGCGAACTTCGAGATCATCTCTTGCGCCATGCCGGCGTCAAGAATCATGTGTGTCCCTACTGTGGTGTGGGCAAGACAACGCGCCAGGAGTGGAACAAGCACATATTAACGCACACCAGGGAGAAGCAGTTCCAGTGCCGGCAATGCGATCATGCCTCCCACAACAAGCAGGCTCTGTCCAATCACGTCAAGGTGGTTCACATGAAGATCAAGAACTTTGCCTGCCAATATTGTGGCAAGACCTTTGGCAAATCCCATGCCTGCAAGATCCACGAGAGACTGCACACTGGAGAGAACTGCTGCGAGTGCAAGATCTGTGGCAAGATCTTCCTCTTCGAGAAGAGATTGACCAAGCATTTGCAGTTACATGAGAAGCGTGATATACCATCTGCGAGTTCTGCGAAGCCTCAAACTGAAGAGGACATTCAGAAGAAGCTTACAGAACCGACGGATGTGAAGAACGTACCTATAATTCCTGCCAAGCCAAAGAATTCACACCGAGTTGAGCGTGTGGACATATCTCAATTGGCTGGCACCGCAGTCAATCCCATTCCTTCCGTAGCGGTGCCATCCTGGTCGCCACAGGTCAACTTCACAAAGAAGGAAGGCCAGCATATTTGTCCAGGCTGCGGACGAGGCTTCAACCACATTGGCAACATGAAGCTCCACTACAAAGTTATACACGACAAGATCAAGGACTTTGCCTGTCGCTTCTGCCCCAAGCGTTTCGGCAAAGCGCAATATCTACAACACCATGAATATACACATACGGGGGAGAAGCCATATGGCTGTAAGATATGCGATAAACATTTTAGTCATGGGTCCTCATTAAGGAAGCATATGTTCTCACACAACAGACCTCCAAAAGTGCCAAAGGCTCAGAAGGCACCAACCAAGTCAAAGGAGCAGAGGcctaaaataaaactaaataagcaGCCAGCAAAGAATTATGAACAGTATCAAGATCCAGCGGCTGAACGAGCGGCAGCAACGGCCGAGTTAATGGCCCAACAGCTGGACGAGAGTGAGGCCAAGCGCAGGGCGGAAGCTAAAGCTCGGCAGATTCAAGAGGCAGCGTGTGAGCAGCTCCAGaaattacagcaacagcagatttCCTATGATAGTTTCACTGaataa
Protein Sequence: MNEETTVSINTVCRTCLSNLQHDEVYDLFVVPGLAKKLCVCTSLSVEHQDGYPKNLCTTCYSRLNDLHDFQKQCVDSVQRFKELLVNNHFTIQTNPVDNFDMLNVAPQDLELPDPLLNSKIEIENEQDVFKMLEDVDKETAEVEKEEDLDNEIESDNDNDDMDFQANSSDSDDEMPLSRLRSNTRTTKAGSKKSDKAEEFSDSDDDDEDKDTIKPNRKRIPAAERHLHRIIECHICRQKFKKAIRYEEHMKHHNDQLPFQCSVEICKKGFTTAAGLRHHMDHAHTELCELIPCTVEGCDESFPRTRMLTHHLKKVHSILKPEVRDHPCTECDKVFRCPTALKKHMYKHTGEEPPISCNICNKRFHINSELRDHLLRHAGVKNHVCPYCGVGKTTRQEWNKHILTHTREKQFQCRQCDHASHNKQALSNHVKVVHMKIKNFACQYCGKTFGKSHACKIHERLHTGENCCECKICGKIFLFEKRLTKHLQLHEKRDIPSASSAKPQTEEDIQKKLTEPTDVKNVPIIPAKPKNSHRVERVDISQLAGTAVNPIPSVAVPSWSPQVNFTKKEGQHICPGCGRGFNHIGNMKLHYKVIHDKIKDFACRFCPKRFGKAQYLQHHEYTHTGEKPYGCKICDKHFSHGSSLRKHMFSHNRPPKVPKAQKAPTKSKEQRPKIKLNKQPAKNYEQYQDPAAERAAATAELMAQQLDESEAKRRAEAKARQIQEAACEQLQKLQQQQISYDSFTE

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00507084;
90% Identity: iTF_00510755;
80% Identity: -