Dmac001342.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Drosophila macrospina
Gene Symbol
-
Assembly
GCA_035042075.1
Location
JAWNLW010000156.1:233230-244483[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 7 0.14 9.1 6.9 0.8 1 23 726 748 726 748 0.95
2 7 1.8e-05 0.0011 19.2 1.1 1 23 754 776 754 776 0.98
3 7 1.5e-06 9.5e-05 22.6 0.1 1 23 782 804 782 804 0.98
4 7 1.6e-06 0.00011 22.4 1.2 1 23 810 832 810 832 0.98
5 7 0.00049 0.032 14.6 1.8 1 23 838 860 838 860 0.97
6 7 5.3e-06 0.00034 20.8 2.4 3 23 868 888 866 888 0.94
7 7 5e-05 0.0033 17.7 0.6 1 23 894 917 894 917 0.98

Sequence Information

Coding Sequence
ATGGCAGTTGAAATAGCAAACTCAGTATTATCGCTACAACCCGCAGTAGAGTTGGAGCCACTGCCGCCGCAATCATTTCATTGGCAACTCGAGGATTACGCATATTTTCACAAGTGCGGTGAAATAACAACATCGCCGGACGTGCAATGTTTTGGTTTCAATTGCGCCTTCTGTCCGGCAATTTGTCTGCAGTTTACGGTGTTCATCGATCACATACGCGGCCATCACATGCAGGATATGCGCCGGCGCTACGAGGTTGCCGAGGACAAAATGGAGCAGACTACGCAGACCGATTTAAATCTAATGCATGGACACTTGGGCAACGTCGGATTAGAAATAggctcaacagcaacaacaattacaacaacaacctcagCAATGGCTACAACAGATGTGCGCCTTGATAAACGCATGAAGAAAACCAATTGGAATGATACAGTGGGGTCGATAGACACACAGAGCGCTGGTACTATGGGACTTTTGGATGTGAGCATGGACTTGGGCATAGACTTGACTGGCATTGTGCACTCAGCtccacagacaacaacaatagcaacaacgcCAACATACAACAATGAAACGCTAACGCAGCTAAGcaacgcagcaacagcaacaacaacaacggcgacgacgacgacaccAGCCGAAATAGACTTCGTTTATGTTATAGAAAATCCATTGCCACCCTCGCCCCCACCCTCGGCTGACATTTCATGCGACGAGCAGAGTCCACGATTGCTGCACTCGATAGAtccatttgaaatgttgcatgggacaagcacacaaacaacGCTGGAGGCGTGCTCCAAAGGTGGCCTTTGTAGCGCTGCCCCGCCTCGCTACGAGACGCGACGCGTGGCAATGCAGCGCAAGCTGCGCGACGCGGAAACGGCCAAGACTGCAGAagagcaaaaacaattacaacagcaacaactacaattacaactTGAATTACAGCAACGTCAACAACTGGAAGAGAATGTGCTGGAACTAACGCCTCCGGCAACGCCGCCAACTCCAGTGCCACCCACCTCGCCCACGAGCAGCGTTGCTAGCAGCGTTGACTTGAAGTTGCGCACACGTCGCGAACTCGAACGTAATCGGGAATTTGTCAGCTGCCTTTTGTTGGAGTATGAACGCAATGAGAAACTATGGAATCCCAAGCATCCAGGGTACAAATACAATGCCAAGCGCAGTGTCTATGGCGAATTGGCGGCTCCACTTCAGACCGTCTGCCAGATGCCGCTAACGGGCGCTGAAATCTTTGCTGTGCTTAAGGAGCTGCGTGGTCGCTATCGTCGAGAGCTGAGCAAACTGAACTCCTTGGGCAACAAGTATAAGCCACGTCTCTGGTACTTTGAGAAGCTGCATTTCTTGCGCGGCGTCATCGAGCACAAGAGAGCCGAAAGGGAGGCAAAGAGCGAATCTACGGAGAGCGAAAAGTCCAGTGAGACGGACAATGAATCGACCACAAAGTCAGCACAGTTCCGTGAGGTTCTCAGCTGTATTATTGATGCGTTTCGGCGCCAGGAGAGCCTGTGGAATCCACAGCACTTTGactacaacaactgttgcaaaAAGGAAGCGTACCGCGAGATCTCGGCGGAGTTGCTCGAGGAGCTCAACTATGAGATGAGTGGCGAGGAGTGCTACAAGGAGATACAAAAGCTGCGCACACGCTATCGTAAGGAACTGCGTATGGTAATCAAACACAAGGGTCTATATCTGCCTAAGCTGTGGTGCTACGATGAGCTGGAGTTTCTGCACAAAATACTCCAGGATCAGATCTTCAACAAGATTAGCAAGAAAAAGGGCGTTGTGGAAACGAATCAGAAGACGAAGTTCATCAATGCCACCTGCATAAGTTTCAACTCGCAGGAGGATCAGCTTCAGTTTGTGGAGATCTATCGCAATTATCCAGCCTTGTGGGATGTGGATCATCCAGATTTTCGCTCCAATGCTTATCGTAATCAGGCCTTGGGCCAAATGCTGGAGGAGCTAAACACCACATTTCAATGCACCTACAATGCCGCACAGCTGGAGAAGACACTGTTTGAGCTACGCAAGGATTTCTCTGCACTGAAACGGAAAATACTCACAAATGCTGCCGGATCAAGCAGCATTCCCCTGCTCCACGCCAAACTGGGACAGTACCTCGAGCAGAATATAGGCCCCTTTCGCTGCGGAGTGTGTGATGAGCTGATCAAGACCTGTGATCAGTACAAGGTACATCGGGCTGGGCACGATGGCACCCAGCCATTCATTTGCACACTTTGTGGCAAGGGATTCCAAATGCCTTGCAACTTAACGGTACACATTCGTCGCCATCGAAGTGACTTTCCCTACGCCTGCGAGCAGTGCGACAAGAGTTTTGCCACATCCACCGAGGTGGCGATACATATGCGCACACACACCGGGGAACGTCCCTACATATGCGATCTCTGTGGCAAATCGTTTAAGACTTGGTCATTCTTTGACATCCATCGACGCACTCACCTCAATCAGTCCACGTTCCATTGCCCCATCTGTGATAAGGGATTCTATGAGAAGAATCGCTTTACCGATCATATGAATGCCCATTTAAACATTCGCAAGCATTTGTGCACCGTCTGTGGCAAGACCTTCACCACATATGGCAACCTGAAGAAGCATACCGAGCTTCATCTGGCCGTGAAGAAGTACAAGTGTGCGGCTTGTGGCAAACGCTTTGCACAGTTTGCCAGTCTGCGGTGGCATAGAAAGCGGGAGCATAACACGGAGCAGagccatcaacagcagcagcagcaagagcagcagcagcatgaggTGGAGATAGGAGAGATAGGAGAAGAGGAACAGGAGATGGTATTCGAGGAGACATAA
Protein Sequence
MAVEIANSVLSLQPAVELEPLPPQSFHWQLEDYAYFHKCGEITTSPDVQCFGFNCAFCPAICLQFTVFIDHIRGHHMQDMRRRYEVAEDKMEQTTQTDLNLMHGHLGNVGLEIGSTATTITTTTSAMATTDVRLDKRMKKTNWNDTVGSIDTQSAGTMGLLDVSMDLGIDLTGIVHSAPQTTTIATTPTYNNETLTQLSNAATATTTTATTTTPAEIDFVYVIENPLPPSPPPSADISCDEQSPRLLHSIDPFEMLHGTSTQTTLEACSKGGLCSAAPPRYETRRVAMQRKLRDAETAKTAEEQKQLQQQQLQLQLELQQRQQLEENVLELTPPATPPTPVPPTSPTSSVASSVDLKLRTRRELERNREFVSCLLLEYERNEKLWNPKHPGYKYNAKRSVYGELAAPLQTVCQMPLTGAEIFAVLKELRGRYRRELSKLNSLGNKYKPRLWYFEKLHFLRGVIEHKRAEREAKSESTESEKSSETDNESTTKSAQFREVLSCIIDAFRRQESLWNPQHFDYNNCCKKEAYREISAELLEELNYEMSGEECYKEIQKLRTRYRKELRMVIKHKGLYLPKLWCYDELEFLHKILQDQIFNKISKKKGVVETNQKTKFINATCISFNSQEDQLQFVEIYRNYPALWDVDHPDFRSNAYRNQALGQMLEELNTTFQCTYNAAQLEKTLFELRKDFSALKRKILTNAAGSSSIPLLHAKLGQYLEQNIGPFRCGVCDELIKTCDQYKVHRAGHDGTQPFICTLCGKGFQMPCNLTVHIRRHRSDFPYACEQCDKSFATSTEVAIHMRTHTGERPYICDLCGKSFKTWSFFDIHRRTHLNQSTFHCPICDKGFYEKNRFTDHMNAHLNIRKHLCTVCGKTFTTYGNLKKHTELHLAVKKYKCAACGKRFAQFASLRWHRKREHNTEQSHQQQQQQEQQQHEVEIGEIGEEEQEMVFEET

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00608653;
90% Identity
-
80% Identity
-