Basic Information

Insect: Drosophila macrospina
Gene Symbol: -
Assembly: GCA_035042075.1
Location: JAWNLW010000340.1:2792458-2794228[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 9 7.8 5.1e+02 1.4 1.8 2 17 11 26 10 27 0.90

2 9 4.6e-05 0.003 17.9 7.8 1 23 299 321 299 321 0.98

3 9 1.6e-05 0.001 19.3 2.9 1 23 327 349 327 349 0.99

4 9 4.1e-05 0.0027 18.0 1.6 1 23 355 377 355 377 0.98

5 9 3.6e-05 0.0024 18.2 2.7 1 23 383 405 383 405 0.99

6 9 1.3e-05 0.00087 19.5 0.5 1 23 411 433 411 433 0.97

7 9 1.5e-05 0.001 19.3 0.2 1 23 439 461 439 461 0.98

8 9 7.8e-07 5.1e-05 23.4 3.2 1 23 467 489 467 489 0.98

9 9 0.0001 0.0068 16.7 1.8 1 23 495 517 495 517 0.99

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	9	7.8	5.1e+02	1.4	1.8	2	17	11	26	10	27	0.90
2	9	4.6e-05	0.003	17.9	7.8	1	23	299	321	299	321	0.98
3	9	1.6e-05	0.001	19.3	2.9	1	23	327	349	327	349	0.99
4	9	4.1e-05	0.0027	18.0	1.6	1	23	355	377	355	377	0.98
5	9	3.6e-05	0.0024	18.2	2.7	1	23	383	405	383	405	0.99
6	9	1.3e-05	0.00087	19.5	0.5	1	23	411	433	411	433	0.97
7	9	1.5e-05	0.001	19.3	0.2	1	23	439	461	439	461	0.98
8	9	7.8e-07	5.1e-05	23.4	3.2	1	23	467	489	467	489	0.98
9	9	0.0001	0.0068	16.7	1.8	1	23	495	517	495	517	0.99

Sequence Information

Coding Sequence: ATGAGCACCAGCAAGTCAGGCGTGGTGCTCAATTGCCGCACATGCACCCGTGCatgtaaacaatataaatcACTACAAGATGAGATCGAGATTGGACCCGAGGGAACCACCACGCTAGCCAGCATGCTAAACTATTGCTCCAATCTCTCATTTGAGCCACAGGACGGTGCATCAATGCCCCAACACATTTGTCTGCATTGCCTGCAGTTGCTGGAGCAGGCATTCTATTTCAAACGCATGGTCATCGATTCAGATGAGCTGCTACGTTTGGGACTCGAAGAAGTTGACaacaatgctaatgccaattcCAACGCTAATGCCAACTCGAACGTTTCGAGCCAGGAATATGTAATGATTGAGCTTCTCGGCGATGAGGCAGAATCAGATGGGACGGCTAAAACGAACTCCGGTCCCCATGATGTTGCTGCACTCGTAGAGACGTATAGTGAACAAGAGCCGGACCAAAAGGAGTTTGTCATTGAAGAGGTGGCTGAGACGGAGGCTAAGGATGATGCCgaaacagaggcagaggaCACAATTGAGACACTTAATGATTTTCAACCGGCTGACATTGAATATGTTACTATAAAAACTGAATATGATTCGCAAGTGGAGGACGAGGATGATATCGAGATTATGGACTCGCCCGGCCTTGAAACGGTAAgtgagcaaatgcaaatacaaatgcttgATGACCAAATGGTTATCATGTCTGGCGAAGAGCCCATCGATGAAGTAATCGGCGAAGTTGAAACCGATGATATATTGGACATTGAGCGCGAAGAGCATTTGCTGACTGGTGATAGCGAGGACGGTGAGGACTTTCTAGATGATTCAATGGATGAAACTGCTTCGAATCAAGTTGTCGCTGGACCTGGCGGCGAAGTGTTGCCGCATGTTTGTCATGTCTGTAATAAGGCATTCCGTCAGCAGTGCCGTCTCAATCAGCATATGCGTTCCCATGTGGACGAGAAGCTCTACACCTGCGAAGTGTGCGGCAAAAAGTTGAAGCACTTGCGCAACTATAAGGAACACATGCTCACCCATACAAATGTTAAACCACATCAGTGTTTGGTCTGTGCACGCTTTTACCGGACCACATCCAGTCTGGCCGCTCACATGCGCACCCATGCCGAGGACAAGCCATATAAGTGTGATCAGTGTGGACGCACCTATGCAGCCTTTGATCATCTGCGTCGACACAAGCTAACGCACACGGGTGAGCGCCCATATGCATGTGATCAGTGTGATAAGGCATATTATGACTCGTCATCGCTGCGACAGCATAAGATCAGCCATACGGGGGAGAAGGCATTCACCTGTGAAATCTGTGGTGTGGGTCTCTCCCAGAAATCGGGCTACAAGAAGCACATGCTGGTCCATTCTGGTGCAAAGCCGCACAAATGTCACATCTGCGGACGCGCCTTTACCTTCACCAGCAACCTGAATGCCCATGTGCGTCTGCACTCTGGCGAAAAGCCATTTAAGTGCGACAAATGCATGAAGGCGTTCCCAACCAAAAAGCGCCTTAATAGCCATCTGCGTGTCCACAATAAGGAGGCGCCAGTGACCACTACAAGCAATACGTTGACCACAAGTACCGCCAGCATACAATCGGAACGCTTGGCGGCGGGCCGTCGCAATGCCATGAATATGCCTGATGTAACCGATCAGCAGGTGTCCACATCCAAGGTTGTTGTAGTCCTCTAA
Protein Sequence: MSTSKSGVVLNCRTCTRACKQYKSLQDEIEIGPEGTTTLASMLNYCSNLSFEPQDGASMPQHICLHCLQLLEQAFYFKRMVIDSDELLRLGLEEVDNNANANSNANANSNVSSQEYVMIELLGDEAESDGTAKTNSGPHDVAALVETYSEQEPDQKEFVIEEVAETEAKDDAETEAEDTIETLNDFQPADIEYVTIKTEYDSQVEDEDDIEIMDSPGLETVSEQMQIQMLDDQMVIMSGEEPIDEVIGEVETDDILDIEREEHLLTGDSEDGEDFLDDSMDETASNQVVAGPGGEVLPHVCHVCNKAFRQQCRLNQHMRSHVDEKLYTCEVCGKKLKHLRNYKEHMLTHTNVKPHQCLVCARFYRTTSSLAAHMRTHAEDKPYKCDQCGRTYAAFDHLRRHKLTHTGERPYACDQCDKAYYDSSSLRQHKISHTGEKAFTCEICGVGLSQKSGYKKHMLVHSGAKPHKCHICGRAFTFTSNLNAHVRLHSGEKPFKCDKCMKAFPTKKRLNSHLRVHNKEAPVTTTSNTLTTSTASIQSERLAAGRRNAMNMPDVTDQQVSTSKVVVVL

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00534746;
90% Identity: iTF_00510711;
80% Identity: -