Basic Information

Insect: Drosophila macrospina
Gene Symbol: Zbtb41
Assembly: GCA_035042075.1
Location: JAWNLW010000591.1:5309712-5311420[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 11 4.9e-05 0.0032 17.8 2.3 1 23 98 120 98 120 0.97

2 11 1.5e-07 9.9e-06 25.7 1.4 1 23 126 149 126 149 0.97

3 11 9.4e-06 0.00061 20.0 0.6 1 23 155 177 155 177 0.98

4 11 1.6e-05 0.001 19.3 0.4 1 23 183 205 183 206 0.95

5 11 1.6e-06 0.0001 22.5 0.9 1 23 213 235 213 235 0.97

6 11 0.007 0.46 11.0 1.0 1 23 241 264 241 265 0.95

7 11 0.0033 0.22 12.0 0.1 1 23 270 292 270 292 0.97

8 11 2.1e-05 0.0014 18.9 2.7 1 23 298 320 298 320 0.98

9 11 1.9e-05 0.0012 19.1 4.7 1 23 326 348 326 348 0.99

10 11 0.0024 0.16 12.5 1.3 1 23 354 379 354 379 0.95

11 11 0.0018 0.12 12.8 0.1 1 20 385 404 385 406 0.95

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	11	4.9e-05	0.0032	17.8	2.3	1	23	98	120	98	120	0.97
2	11	1.5e-07	9.9e-06	25.7	1.4	1	23	126	149	126	149	0.97
3	11	9.4e-06	0.00061	20.0	0.6	1	23	155	177	155	177	0.98
4	11	1.6e-05	0.001	19.3	0.4	1	23	183	205	183	206	0.95
5	11	1.6e-06	0.0001	22.5	0.9	1	23	213	235	213	235	0.97
6	11	0.007	0.46	11.0	1.0	1	23	241	264	241	265	0.95
7	11	0.0033	0.22	12.0	0.1	1	23	270	292	270	292	0.97
8	11	2.1e-05	0.0014	18.9	2.7	1	23	298	320	298	320	0.98
9	11	1.9e-05	0.0012	19.1	4.7	1	23	326	348	326	348	0.99
10	11	0.0024	0.16	12.5	1.3	1	23	354	379	354	379	0.95
11	11	0.0018	0.12	12.8	0.1	1	20	385	404	385	406	0.95

Sequence Information

Coding Sequence: ATGGTACGCAGTCGTCGCAGTCTCTCCAAGGAGGATGCCGCATCTTTGCTTACGGATAGCGGCATTTCGCTATCATCGCCGCCGGCGGCACGCGAATCTTCACCAACGGGAGCGCCCATCAAGCGACGCAAGAGCAGCCTCAATAGTTTGCAGGATTTGTATGTGGATGGTGAGCATGATGCCGAACAGGATTCCACagatgcagatggagatgcggatgcggatgcagaCTACGTGCAACCGGAGCCAAAGAAATCACCACGCAAAGCTGAAGCAACAAGGCGCAAGCAGCACGTGTGCAATCATTGCTCCAAGGAATTTGGTGGCAAAACAGATCTATTGCGTCACATGCTCATCCATTCAGACGAACGTCCCCATAAGTGCACAGAGTGCGGCAAATCCTATCGCCAGGCGGTTAACCTCAAGAACCACATAACTACAGCCCACGAACATAAGAAACAATTCTCCTGCACGGTTTGTCCCAAATCCTTTGCCCTTAAAGAACGCCTCAGGCTGCACATGCGTCTGCATTCGGGCGAGAAGCCATATCCGTGTGCACTGTGCGACAAGCGATTTGCTAGAGGCGGTCAGctgcagcagcacatGGTGTCGCACCATAAGACGAGCATACAGCAATTCAACTGCACCAAATGCTCGGCTAGCTTCTCGACGAATGCCAATCTTCGCGTGCATATGGAACGCCACGAGCAGGGCATGGAGCATAGATGCTCCATCTGTGAGAGTCAATTTGCCAATGAATTGGCGTTGCGTGCCCACATCAATCAGGAGCACCACAAGCTGAGCCAATTCGATTGTGAAATATGCCACAAGACCATCGAACCGGATGAGGATCTGGCCATCCACATGCAGAAACATGCTGCGGTCAAGACACACGTCTGTGAGGTGTGCAATTCGTATTTTACACAAAAGTCGCAGTACAATGTCCACATGCGAATGCATACGGGAGAGCGACCGTATCAGTGTCGGATCTGTCATCAGACATTCGCCCACTCCAGCGTGTTGAAGCTGCACATACGCAAGCACACGGGAGAAAAGCCCTTTCGCTGCCAGCTCTGTACGGATGAAGTGGCCTTCTCACAGCTGGCACATCTCAAGAATCATATGAAGAAGATACATAAACAGCAGAAGCCGTATATGTGCGATGGCTGCCATGAGTTTTTTAAGATTAAAGTGGAGCTGCAGGCGCATGTCGAGCAATGTGCCAAGTGCCAGACAATGGAGGAGCCCAACGATAGCCAGACAGAGGATACCCAAACGCTGTCCACAATACGCTTTAATATGGCCGTGGTGTTGAAGAAAATCAGCTCGGCCCAGAAGCTAAGACAGCTCGGTTACGAGAAGCGTCTAATTGATAATGTCATCATTGCCTCACTTAAGCTGGCCCAGCGTCCATCGCACGACGATGCAACGCTGACCCCGTTGGCCAGACTACGATTGAATGTTGAGGAGTTTCTAAAGTGGATTGTGCCGGCGCCCACGATGCAAAAGTTCACCGAGGAGCTACTCTCGATCGATACGATACTCGACAAGATTGCGACCATGTATATGAAACAAAAGTAG
Protein Sequence: MVRSRRSLSKEDAASLLTDSGISLSSPPAARESSPTGAPIKRRKSSLNSLQDLYVDGEHDAEQDSTDADGDADADADYVQPEPKKSPRKAEATRRKQHVCNHCSKEFGGKTDLLRHMLIHSDERPHKCTECGKSYRQAVNLKNHITTAHEHKKQFSCTVCPKSFALKERLRLHMRLHSGEKPYPCALCDKRFARGGQLQQHMVSHHKTSIQQFNCTKCSASFSTNANLRVHMERHEQGMEHRCSICESQFANELALRAHINQEHHKLSQFDCEICHKTIEPDEDLAIHMQKHAAVKTHVCEVCNSYFTQKSQYNVHMRMHTGERPYQCRICHQTFAHSSVLKLHIRKHTGEKPFRCQLCTDEVAFSQLAHLKNHMKKIHKQQKPYMCDGCHEFFKIKVELQAHVEQCAKCQTMEEPNDSQTEDTQTLSTIRFNMAVVLKKISSAQKLRQLGYEKRLIDNVIIASLKLAQRPSHDDATLTPLARLRLNVEEFLKWIVPAPTMQKFTEELLSIDTILDKIATMYMKQK

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01324297;
90% Identity: iTF_00520775;
80% Identity: -