Dmac011853.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Drosophila macrospina
Gene Symbol
-
Assembly
GCA_035042075.1
Location
JAWNLW010000539.1:5704995-5709606[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 26 0.002 0.13 12.7 2.9 1 23 214 236 214 236 0.96
2 26 0.027 1.8 9.1 1.4 1 23 242 264 242 264 0.98
3 26 0.041 2.6 8.6 1.0 2 23 296 317 295 317 0.96
4 26 0.044 2.9 8.5 1.4 1 23 392 415 392 415 0.93
5 26 0.64 42 4.8 2.3 2 22 427 447 426 447 0.96
6 26 0.32 21 5.8 1.4 1 23 456 478 456 478 0.97
7 26 0.073 4.8 7.8 0.4 3 23 498 518 497 518 0.96
8 26 0.004 0.26 11.7 0.3 1 23 594 617 594 617 0.95
9 26 0.0038 0.25 11.8 0.4 1 22 626 647 626 647 0.95
10 26 0.51 33 5.1 10.6 1 23 656 678 656 679 0.95
11 26 5.6e-05 0.0036 17.6 0.3 2 23 703 724 702 724 0.97
12 26 8.9e-06 0.00058 20.1 4.7 1 23 732 754 732 754 0.99
13 26 0.027 1.7 9.2 1.3 1 23 904 927 904 927 0.95
14 26 0.79 52 4.5 6.8 1 23 934 958 934 958 0.92
15 26 0.088 5.7 7.5 0.5 1 23 964 987 964 987 0.91
16 26 1.1e-05 0.00069 19.9 1.9 1 23 1012 1034 1012 1034 0.97
17 26 0.00014 0.0089 16.4 0.9 1 23 1041 1063 1041 1063 0.98
18 26 0.011 0.75 10.3 0.0 2 21 1090 1109 1089 1110 0.93
19 26 0.012 0.8 10.2 3.9 1 23 1155 1178 1155 1178 0.96
20 26 0.0064 0.42 11.1 0.5 1 23 1215 1238 1215 1238 0.96
21 26 0.00095 0.062 13.7 3.5 1 23 1262 1285 1262 1285 0.97
22 26 1.3e-05 0.00087 19.5 0.1 2 23 1309 1330 1308 1330 0.95
23 26 4.6e-05 0.003 17.9 2.9 1 23 1336 1358 1336 1358 0.99
24 26 5e-06 0.00033 20.9 1.9 1 23 1364 1386 1364 1386 0.97
25 26 2e-07 1.3e-05 25.3 2.4 1 23 1392 1414 1392 1414 0.99
26 26 0.035 2.3 8.8 0.2 1 21 1420 1440 1420 1444 0.91

Sequence Information

Coding Sequence
ATGTTGCCGACCCATATATGCCGCACCTGTGCGGTATATGATGTGCATTTATTGGCGCTCTCCACACACATCGAGAAATAtccaaacaaaagtttatgCGACATGTTGCATGAGTTAACACAAAACGATCCCTTAATGGAACACTCCGATGATAATCTGCCTCAGTATCTGTGTGGCGACTGTTTGCGTAAGCTGAAAGATGCCTACGCATTTGTATTGCAAGCACGCCAGGTACAAGAGCAACTGTTGCACAAAATACGCAATGGATTACAGTGTCTGGATGAGACACCTATAGACATAGCCACGCAGCACATaaagacagaaacagaaatttCCTTGGAGCAAGCCAACAGTGAAGCACCATTGGACGTCAACGATCATGAGGTTTCAACTatatctgttgctgctttaaaAATGCAACCGGAGAGTGAGACCGACAGTAGCCATTCAGAAGTGGCTGAtgATAATGACCTAGACGCTAAGTCCATGCAGCTGAGGCGCAGCACACGCAAAGCGAATCTTGCCTCAGACAGCGAAAATGAAGCGACTTCggaaaatgtacatatattgcCGCCAAAGCGACGTCGCGGTCGGCCTGCACGTAATTCGCAAAAGGAAACTATCAACAAAGATGGACGCCATGCCTGCAAGGTGTGTGGTAAGACGTTCTCATGGCATCGGGACATGCAACGCCATGCCCGCGTACACTTTGAGCAAGCTGGTTACGTGTGTGAGAGCTGTGGCAAGGGGTTCCTTCGCAAAGACAAATACATGTTCCATATGCGATCGCACGAGAAGCGTCAAGCTAAACGTTCGGCTCTGCAAGTGGGCAGCGAATGGCGCTTTGCGGAGCGCCTCTACAGTTCGGGACGTCTCAAGCGAGTGGAGTGTATGTTGTGCGGGTTAAAGTGCCAGCGGATTCAGGATCTTCGTAAGCATCTGGCTACTCACGTTAACATTGAAACCTTGTCGAGTCTCAGTACCAATAGCCATGTTATCAAGGAACAGTTTCACGACAAGCAATTGgacttaatacaaattaagcaaCAGGTGTGTGAGGACATAGCCAAAGGAAGCGAATATCTAGATAAATACTGTCTTGTGGTCAATGCATACGGCTATGAACTCTGTCTGAGCGACTCGGACGAAGAGTTGGCTGAAATGCCGCCTCCATACCAATGCTTGCCTTGCAACACGTTCTTCTCACGTAAATATCGTCTGATGCAGCACACGCTGGAGGAGCATACCCAACCGACAACTGGTACAACTCCATGGCAACGTTGCAACCATTGCCAAATTGGGTTTGTGTGCTTAAAACTGCTGGAGCAGCATCAGCGCACACAATGCAACAATCAGCTGAAACGTTATAGTTGCCCAAAATGTCCAGGCAAATTTATGTGGTTGCGCAATTTGAAGCAACATGCGTGCTCCCATCGCACGAAATTTTCAGAGGAGGAGGATCGGGAGAAATGGCAAAGTCGTCAGATTCTGTGCTGTCTTTGCGATAAGCAACTGCCCAGTATGTCGGAACTACGTGCTCATCTAGTCATACATAGCGATGGGCGAAACGGGGTTGATTTGGATCGAGATGCTACCTTCTTTCGTTGTTACTACCCTGATGGTTTGACCTACACGCAAACTGAGCTCAGCACACGAATTGCAAGTGACTTTGAGGAACAGGATTATGGTCGCTACTTCAATGCATGCACTGGCAGCGGCCAAGAGCTGGATTTCTTTGACTCTGATCCGGATTTATACGATGAGTCAGCCTCAGCTGTGCATTCGTGTGCTTTGTGTGGCATGAGTACAATACGCCTTGCCCAACTCCTGAAGCATCAACAAGAAGACCACAGCGAGATGAATATAACATTGCCTCATAGCTGCGATACGTGTGAGTTGGGATTCGTTTCTGAATCGCTGCTTCAGCAGCATCGCCGACGTATCTGCGCCAAGCGTCATGCAAATTACCATTGTCATCACTGCAATCTCCACTTTATCTGGCAGTCCAACTATGAGCGGCACTTAGAATCACATCACGAAGGGGAAGCGGAGGAGCATGCGCCCATTACCAGGCTAAGAAGCCAACGCCAACAACGCGCCAAACTACAGTGCAACGAGTGTGATAAGgtGTTCATCTGGCCAAAGGATCTGACGCGTCACAAGCGCATTCACCAGCCGCAGGCATCGGCACAATTCAAATGCAGCTACTGTGAGCGCAAGTTCCATCGCAAGGATGGCCTCAAGTCGCATATGCGTGTGCACGGCGAGCAGCAGTTGGATGTGACGTTAATGCCTAACAGTGAACCAGATGCATCGATCTTACAGCGGATGCCAATGGTGTTGACGCCAATGTGTCAACCAAATGGATGCAAGCAGATTCAGTGCATGATCTGTCTGTCTCAGCACACGAAGATCTCTGATCTGCGCACGCATTTGGAGAATCATCAGTTTGTTGTGGAGTTTGCGGAGGAGCGTGCCAAGCCGGAGAGCATTGCGAGTATTGGCCGAGCTCTATATCCGGAACAGGTGACTCCGCTGGATAAGCTACAGTTAATTGAACGCATTCAAAGCGATGTGGGCAGAGGGAATGATTTAGAAAGATTCATTTCGATAACCAATGAGGCAGGCATTGAGCTTAGTCTTGACAGCAGCGAAACTGAAACGGATTCGGACTCAGCCGATGTTGGAATGAGCAGCAGTGGACGACAATACAATTGTGATCTGTGTCAGCTGAAGTTGCCGCGTAAACACCAACTCTATGCCCATCAGCTGGAACAGCATACATGGCAGCAAGCAACCCACATTTGTAGCCACTGTCAGGCCAGATTCATCAGTGAGCAGTTGCTGGATCATCACTATCGTACGCTATGTCACAATGCCCATAAGCGATTTCTCTGTCGGAAGTGTCCATTGCGCTTTCGCTGGCGGGACAACCTGAAGCTGCACACGGATGTAGCGCATGGGGAAGTAACTGGAGAACAGACCAGTCTCAGCATCCAATTGAATGGACAAAGTCTCCTTCCTGTTATCAGCTACGATTGTACCGAGTGTAATCGTagctttaaaatgcaaaaggatCTCACACGGCACACGCTGATGCATGCCCAGGAGTCGAGCATTTATCGGTGTCGCTGGTGTGCCCGACGTTTCTATCGCCAGGCAAATCTTCTGCAGCACATAGAACGTCATGGCATCAATGCCGCACAGCTGCCTTATGCCGAATCCCTGCTTAATGCCAGTCGTCATCCTCATGGCCAGAAGTGCATCGAATGCAAGGTGTGTGATATACGTTTCCCCACAATTGCTGCATTGCGTTCCCATTTGTCGTCCACGGCGAGCGGGACTCATCATAAGATTGAATCGATGCTCAACTATTCGATTACCAATCAGCTGGGCTATGAGCTGCACTTGGACGACTCGGAAACGGATGAGGAGGCCAAGCCACCTGGCATACCTTCACACTATACCTGCGGGATGTGTCAGCTCCGTTGTGTGCGCAAATATGAgctgcatcagcatcagcaggcGATGCATAGGCTAGAAAGGATTACCGATGGCTGTAATCAGTGCATTTATAAGAGTGTTTGCCCGGATCTAATCGCATATCATCAGCGTGTGCAGTGTGGAAATACGGAGAAGCAGTTTAAATGTGTCAACTGTGGTTATAAGTTTATGTGGGAGTCCAATCTGCAGCTGCACATTCAATTGCAGCATCCCAGCAATGATCAGGAGGAGACGCCGCCTGCGCCGGCTCCAGAGACACCCGCTTCAGAGTGCCAGATCTTTCAGTGTGGTCAGTGCCCGCGTAAATATAATCGAAAGGATCGATTGACGGCTCATGTAAAGAAGTGTCATGCACCAGGTGTAGCGAGTCCAGTGAAAACAACGACGCCTTCAACTGTCGCCAAACAACAGAAGAGTTTCCTCTGCGCATTTTGCGGCAAGGCAGTGAGCTCATCCTCCAATCTCATTATACACATCCGTCGACATACTGGCGAGAAGCCCTTCAAGTGCGACTATTGCGACATGGCTTTTCCTCGCTCTTCCGATCTGCAGTGCCATCGACGAACTCACACTGGCGAACGGCCGCATGTGTGCACCGTGTGTCAAAGAGGATTCGCCCGCTCCtacaagttgcagcaacacATGCGAATACACAATGGCGAACGACCCTACAAGTGTACCTATTGCGAGAAAAGCTTCACCCAGTCCAATGACCTTACGCTCCACATCCGACGGCACACGGGCGAACGTCCCTATCAATGTGAAACCTGTGGGGATCGCTTCATTCAGGGCACAGCACTCAAGAATCATCGACTACAGAATGGGCATTACGAGACAGTGGAAGGTCtagctaaaaataattaa
Protein Sequence
MLPTHICRTCAVYDVHLLALSTHIEKYPNKSLCDMLHELTQNDPLMEHSDDNLPQYLCGDCLRKLKDAYAFVLQARQVQEQLLHKIRNGLQCLDETPIDIATQHIKTETEISLEQANSEAPLDVNDHEVSTISVAALKMQPESETDSSHSEVADDNDLDAKSMQLRRSTRKANLASDSENEATSENVHILPPKRRRGRPARNSQKETINKDGRHACKVCGKTFSWHRDMQRHARVHFEQAGYVCESCGKGFLRKDKYMFHMRSHEKRQAKRSALQVGSEWRFAERLYSSGRLKRVECMLCGLKCQRIQDLRKHLATHVNIETLSSLSTNSHVIKEQFHDKQLDLIQIKQQVCEDIAKGSEYLDKYCLVVNAYGYELCLSDSDEELAEMPPPYQCLPCNTFFSRKYRLMQHTLEEHTQPTTGTTPWQRCNHCQIGFVCLKLLEQHQRTQCNNQLKRYSCPKCPGKFMWLRNLKQHACSHRTKFSEEEDREKWQSRQILCCLCDKQLPSMSELRAHLVIHSDGRNGVDLDRDATFFRCYYPDGLTYTQTELSTRIASDFEEQDYGRYFNACTGSGQELDFFDSDPDLYDESASAVHSCALCGMSTIRLAQLLKHQQEDHSEMNITLPHSCDTCELGFVSESLLQQHRRRICAKRHANYHCHHCNLHFIWQSNYERHLESHHEGEAEEHAPITRLRSQRQQRAKLQCNECDKVFIWPKDLTRHKRIHQPQASAQFKCSYCERKFHRKDGLKSHMRVHGEQQLDVTLMPNSEPDASILQRMPMVLTPMCQPNGCKQIQCMICLSQHTKISDLRTHLENHQFVVEFAEERAKPESIASIGRALYPEQVTPLDKLQLIERIQSDVGRGNDLERFISITNEAGIELSLDSSETETDSDSADVGMSSSGRQYNCDLCQLKLPRKHQLYAHQLEQHTWQQATHICSHCQARFISEQLLDHHYRTLCHNAHKRFLCRKCPLRFRWRDNLKLHTDVAHGEVTGEQTSLSIQLNGQSLLPVISYDCTECNRSFKMQKDLTRHTLMHAQESSIYRCRWCARRFYRQANLLQHIERHGINAAQLPYAESLLNASRHPHGQKCIECKVCDIRFPTIAALRSHLSSTASGTHHKIESMLNYSITNQLGYELHLDDSETDEEAKPPGIPSHYTCGMCQLRCVRKYELHQHQQAMHRLERITDGCNQCIYKSVCPDLIAYHQRVQCGNTEKQFKCVNCGYKFMWESNLQLHIQLQHPSNDQEETPPAPAPETPASECQIFQCGQCPRKYNRKDRLTAHVKKCHAPGVASPVKTTTPSTVAKQQKSFLCAFCGKAVSSSSNLIIHIRRHTGEKPFKCDYCDMAFPRSSDLQCHRRTHTGERPHVCTVCQRGFARSYKLQQHMRIHNGERPYKCTYCEKSFTQSNDLTLHIRRHTGERPYQCETCGDRFIQGTALKNHRLQNGHYETVEGLAKNN

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00558059;
90% Identity
-
80% Identity
-