Basic Information

Insect: Drosophila lutescens
Gene Symbol: RREB1
Assembly: GCA_037075285.1
Location: JBAMCF010000074.1:124361-126430[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 6 1.3e-05 0.001 19.7 3.3 1 23 455 477 455 477 0.99

2 6 0.053 4.3 8.3 1.1 2 23 490 511 489 511 0.95

3 6 3.5e-05 0.0029 18.3 0.9 1 23 517 539 517 539 0.98

4 6 3.4e-05 0.0028 18.3 2.9 1 23 545 568 545 568 0.95

5 6 0.0024 0.2 12.5 6.4 1 23 575 597 575 597 0.98

6 6 1.9e-05 0.0015 19.1 1.0 1 23 602 625 602 625 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	6	1.3e-05	0.001	19.7	3.3	1	23	455	477	455	477	0.99
2	6	0.053	4.3	8.3	1.1	2	23	490	511	489	511	0.95
3	6	3.5e-05	0.0029	18.3	0.9	1	23	517	539	517	539	0.98
4	6	3.4e-05	0.0028	18.3	2.9	1	23	545	568	545	568	0.95
5	6	0.0024	0.2	12.5	6.4	1	23	575	597	575	597	0.98
6	6	1.9e-05	0.0015	19.1	1.0	1	23	602	625	602	625	0.97

Sequence Information

Coding Sequence: ATGGAGGCGTCGCCGTCCTATCCCGATTTGGCGACTCTGTGCCGGCTGTGCCTCAAGGAGCACCAGGATGCGTACGCGATCTTCGAGGGGGACGATGCCCAGCTCTCGATTCCCGTGCGCCTGATGGCCTGCGTCGCCCTGGACGCTAAGGCGACGGATAGTCTGCCGAAGCGGATCTGCCAGGAGTGCCGCTACCAGCTGGAGAAATCCTTCCTATTCCGCCAGCGCTGCCAGTGGGCGGAGAAGAAGCTGCGCAAGCACATCCGCCTTCTGGGCCTGGGCAAGCGGAGTCGCGTCTTCTCCAAGGATCCGGACGACTACGATGAGGACGAGCTGGAGTTCGAGGACTCCATCGGCTTCATCGAGGCGCAGGACAAGGCGCGCCAGCTGGAGGACGAAAAGTGGCGCGAGGAGTtcaaggaggagcaggaggcggAGTTAAACAAGCGGCTGGTCAAATCCCGACTAGAACTCCGAGCCAAGCTGACCACGGAGCTGCGCAAGGGACTCGCCGAGGAGGTACGCAGTCAGGTCCGCGAGGAACTGGCCGAGGAGGTTCGCAGTCAGGTGCGCGAGCAACTGGTCGAGGAGGTGCGCAACCAGGTGAGGGAAGAACTGCGACACGAGGTTAGCGAGGACATGCGAAAAGAGCAGCAGGCCATGCTCTTGGGCGAACTGGAGGTGTATCTCACCGAAAAGAAGGCCGGTCAGTGGGAGCCCTTGGATGGCGCTGAAGAGCCGGATCCAAAGTCGCAGGTCAAGGTGGACTCCTCCTCTTCCAGGCACAAGTTAAAATTACCTCACAAGCGGCGCCTCAGCTCGCCCAGCAAGCCACCGCACGTGCCACTGACCATGAAGGCGGAAAAGGAAGAGGAGTACGTGCTGGGGTGCAACTCAAACATGGATATAGAGGCCCTCGAACTGGAGGATGGAGTGCCCACGGAGGATGGGGAGGACGACTACAGGGACATCAAAATGGTCGGGACCGGGGATGTGGTGCACACCGAGGACGGGGAGATCTACATTATAAATGCGCAGGACCAAAAGCCAGAATCCCCGCCCGAATTCGACGAAGACAACGAAATCACGTCCTACAACATCAAGGAAGACGGCGAGATCCAGTTTAGTGGCGAGAAATCGGAGGAAATCGAGGACGTGGTAGTGTTTAACTTGGGCGACGAGATGTCTGAAGAGCAACAAGTCTTTAATTTTGACGAGAGTGTAATTATTGTGGAAAAGGAGCAGCTGAACAGTGACGAGCAGACGCCAGTGAAACGAAAGAGATCGAGTGAGTTGGTGTTCAAGCAGGCCTCCAGTTGCCCTCAACCGAAAACCGGGCGGGTAACGGACACGGTCAAGTCTTTCCAGTGCCATTTGTGCCCGGTGGCCTTTGCCACGCAGAAGCTGCTGACGCGCCACCACAATACCCACATCAAGGGCCTGAAAAGCGGCAAGGGCGGCACGCTCAAGTGCCCCAGCTGCTCGCTGCAACTGTCCTGCGCCAGCTCCCTCAAGCGCCACATGATCATTCACACGGGCTTAAAACCTTTCAAATGCACCGCGTGCGAATTGTCCTTCTCCCAGCGCGAAGTGCTCAAGCGTCACATGGACACCCATACGGGAGCCAAGCGCCATCAGTGCCCCCAATGCTCGAGTTGTTTCGCCCAAAAGTCCAACTTGCAACAGCACATAGGTCGCGTCCACATGGGTAACTCTCGGACGCACAAGTGCCACCTGTGCCAGCGCAACTTTAATCACGTTTCGGGCCTTAGCCGCCACCTGGTCACCCACGCTGGCGTCATGTTCTCCTGCAAGCAGTGCGGCCGGCAATTCAACGATCGCAGCGCCGTTCAACGTCATGTGACGACCATGCACAAGGTGAAGGACAAATCCGCGGACTACATATCTGAGAACGAGATCGGCGAGCTCGACTTTCAGCCAGTGTCATCATAG
Protein Sequence: MEASPSYPDLATLCRLCLKEHQDAYAIFEGDDAQLSIPVRLMACVALDAKATDSLPKRICQECRYQLEKSFLFRQRCQWAEKKLRKHIRLLGLGKRSRVFSKDPDDYDEDELEFEDSIGFIEAQDKARQLEDEKWREEFKEEQEAELNKRLVKSRLELRAKLTTELRKGLAEEVRSQVREELAEEVRSQVREQLVEEVRNQVREELRHEVSEDMRKEQQAMLLGELEVYLTEKKAGQWEPLDGAEEPDPKSQVKVDSSSSRHKLKLPHKRRLSSPSKPPHVPLTMKAEKEEEYVLGCNSNMDIEALELEDGVPTEDGEDDYRDIKMVGTGDVVHTEDGEIYIINAQDQKPESPPEFDEDNEITSYNIKEDGEIQFSGEKSEEIEDVVVFNLGDEMSEEQQVFNFDESVIIVEKEQLNSDEQTPVKRKRSSELVFKQASSCPQPKTGRVTDTVKSFQCHLCPVAFATQKLLTRHHNTHIKGLKSGKGGTLKCPSCSLQLSCASSLKRHMIIHTGLKPFKCTACELSFSQREVLKRHMDTHTGAKRHQCPQCSSCFAQKSNLQQHIGRVHMGNSRTHKCHLCQRNFNHVSGLSRHLVTHAGVMFSCKQCGRQFNDRSAVQRHVTTMHKVKDKSADYISENEIGELDFQPVSS

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00548312;
90% Identity: iTF_00605828;
80% Identity: -