Basic Information

Insect: Drosophila lutescens
Gene Symbol: GFI1
Assembly: GCA_037075285.1
Location: JBAMCF010000276.1:220421-237661[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 6 0.0002 0.016 15.9 3.6 1 23 497 520 497 521 0.96

2 6 0.0003 0.024 15.3 0.5 1 23 526 548 526 548 0.97

3 6 3.5e-07 2.8e-05 24.6 1.9 1 23 554 576 554 576 0.98

4 6 1.2e-05 0.00096 19.7 4.2 1 23 582 604 582 604 0.97

5 6 2.1e-07 1.7e-05 25.3 2.5 1 23 610 632 610 632 0.98

6 6 5.6e-05 0.0045 17.6 4.1 1 23 638 661 638 661 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	6	0.0002	0.016	15.9	3.6	1	23	497	520	497	521	0.96
2	6	0.0003	0.024	15.3	0.5	1	23	526	548	526	548	0.97
3	6	3.5e-07	2.8e-05	24.6	1.9	1	23	554	576	554	576	0.98
4	6	1.2e-05	0.00096	19.7	4.2	1	23	582	604	582	604	0.97
5	6	2.1e-07	1.7e-05	25.3	2.5	1	23	610	632	610	632	0.98
6	6	5.6e-05	0.0045	17.6	4.1	1	23	638	661	638	661	0.97

Sequence Information

Coding Sequence: ATGGACGTGGCCAAAATGCAAGCCACTTCCGGTCAGCATCTACTGCATCCGGCCGCACCGCCcgcccaccagcaccacctgCCCCTCGACTACAGTCTGGGCAACTTTAAGCCAGCCATTGCGGCGGACTTTCCCGGCTCCTTCCTCACCAGCCAGCAATCGTCGTCGGCCTCAAATTCGGCATCGAAttccgccgcctcctccgcctcgcTGCAGGTGCGGGATCTCAGCGCCCTGACGGCCATGGCCACGATACCCTCGCCCACGCAGCTGCTCCACCAGCGCATCCAGTTGTCCGCGGACGCGGCGCTGGGCcaccaccaacagcagcaggcccACAACTCCAATCCTCCGCAGCCGCAGATGCCGCCGGCCTCCACATCGCCGCACGAATATGCGCCCATGTCCGCCTTCAAAGCTGTGCTCCCCAAGAAGCGAAACTCCGACGATGCCTCGCTAGCATTTAGCATAAGCAGACTGGTTAAGACTGAACAACTGACGGCCATGGCGGCGGCGGCCGTTGGCCTGAAGCCGCCGACTTCCCTGGAGGACAACAACAACTCAATCTCGATGCTGAGCAAAAACCAACAGATGCACCAgcagcaccaacaacaacagcaaccgcATCTTCCCCAGCGCTCCAAGCCGGCCTTCATCAGCGCCAGCGAGAAGCTGCGCCGACAGTCGCGATCCCGCTCCAGGTCGAGATCCAGGAGTCCCTGCTCCTCGCAAATCGACATGGATGATGCGGAATCGCACCACTCCCTGCACTCCCGCTCGCGATCCCGTTCCCGCTCCCATTCCCGCTCCCGCTCGCACTCGAGCAGTTCGTCCGTGGAGCTGGAGGTGGACTCGCCACCCGGCAGTCCGAGGATCAGCTCGCCCAGCGGCACCTCTGCATCCGCCTCCGAACTGCTGATCACCGCCAATGGCGGCGGTCGCAGCATAGGATCCAAGAAGTCGGACCTCTTCTCCGTCTCCGCTCTACTTCGACGGGACGAACCGCCGGCGAGACGGACGCCCCGCAGCCCACCACTCGGACATCTGGCCGCCAGTGGACTGGCCATGCCCTTCAATCCGCTGGAGGCGATGCGGCAGGGCTATCCGCCCAACTACGATGCGGCCATGTTCCAGCGACCGCTCTTCTCGCCCGCCCTGCCCTTCTTCGCCGCCGTCGCCTTTCACCAaggtcagcagcagcagcaacagcaacaacagcaatccGGTCTGGGAGCAGGCTACCATCCGGATTCGCAGGAAAATCTCTTCCGTCTGCGGAGTCTGATGGTGCCGCTCCAATCCGCCGGACAGAACAACTCctcggcggcagcggcggcggctgcagcTGCGGCAGCGGCCGTCGGCGTGGGCGTCGGTGTGGGCGTGCCACCCAACGGCGGTCATCTCGGCCTGCCCCACTCGCCCCACCTGCACCACTTCCACCACATGGCCGCCAAGTGGCCGGGCCTGCACCAATTCAGCGACCTGTACTCGTGCATGAAGTGCGAGAAGATGTTCTCCACGCCCCACGGCCTCGAGGTCCACTCCCGCCGGACGCACCACGGCAAGAAGCCCTACGCCTGCGAGCTCTGCAACAAGACCTTCGGCCACGAGGTCAGCCTCAGCCAGCACAGGGCGGTGCACAACGTGGAGAAGGTGTTCGAGTGCAAGCAGTGCGGAAAGCGCTTCAAGCGCTCCAGCACCCTGTCCACCCACCTGCTCATCCACAGCGACACGCGGCCTTATCCCTGCAACTACTGCGGAAAGCGGTTCCACCAGAAGAGCGACATGAAGAAGCACACCTACATCCACACAGGTGAGAAACCGCACAAGTGCCAGGTGTGCGGCAAGGCCTTCAGCCAGAGCTCCAACCTGATAACGCACTCCCGCAAGCACACCGGTTACAAGCCCTTCTCCTGCAAGCTGTGCCACAAGGCCTTCCAGCGGAAGGTGGATCTGCGGCGGCACAAGGAGACACAGCACACGGACCTGCGCGTCCACCTGGGCAAGGTGGACTTCatgtcggcggcggcggcagcggcggcctCAGCCGAACTGGCGGGCTCGGTTCCGGCCGGAGTCCAGGCGGGGAATCAGGGAGCCAGTGCGGTCAACTCGGCCGCAAACGGGGCTCCTCCGATGGGCGCACTCAACTGCCAGAAGGTTTCGCTCCTGGTATAA
Protein Sequence: MDVAKMQATSGQHLLHPAAPPAHQHHLPLDYSLGNFKPAIAADFPGSFLTSQQSSSASNSASNSAASSASLQVRDLSALTAMATIPSPTQLLHQRIQLSADAALGHHQQQQAHNSNPPQPQMPPASTSPHEYAPMSAFKAVLPKKRNSDDASLAFSISRLVKTEQLTAMAAAAVGLKPPTSLEDNNNSISMLSKNQQMHQQHQQQQQPHLPQRSKPAFISASEKLRRQSRSRSRSRSRSPCSSQIDMDDAESHHSLHSRSRSRSRSHSRSRSHSSSSSVELEVDSPPGSPRISSPSGTSASASELLITANGGGRSIGSKKSDLFSVSALLRRDEPPARRTPRSPPLGHLAASGLAMPFNPLEAMRQGYPPNYDAAMFQRPLFSPALPFFAAVAFHQGQQQQQQQQQQSGLGAGYHPDSQENLFRLRSLMVPLQSAGQNNSSAAAAAAAAAAAAVGVGVGVGVPPNGGHLGLPHSPHLHHFHHMAAKWPGLHQFSDLYSCMKCEKMFSTPHGLEVHSRRTHHGKKPYACELCNKTFGHEVSLSQHRAVHNVEKVFECKQCGKRFKRSSTLSTHLLIHSDTRPYPCNYCGKRFHQKSDMKKHTYIHTGEKPHKCQVCGKAFSQSSNLITHSRKHTGYKPFSCKLCHKAFQRKVDLRRHKETQHTDLRVHLGKVDFMSAAAAAAASAELAGSVPAGVQAGNQGASAVNSAANGAPPMGALNCQKVSLLV

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00591916;
90% Identity: iTF_00619335; iTF_00548266; iTF_00504877; iTF_00539873; iTF_00596866; iTF_00592607; iTF_00591916; iTF_00486768; iTF_00565591; iTF_00605047; iTF_00602812; iTF_00605784; iTF_00505595; iTF_00578749; iTF_00581759;
80% Identity: -