Basic Information

Insect: Drosophila lutescens
Gene Symbol: -
Assembly: GCA_037075285.1
Location: JBAMCF010000514.1:520605-522067[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 5 2.3e-05 0.0018 18.9 0.1 2 23 227 248 226 248 0.97

2 5 6.8e-09 5.5e-07 30.0 0.0 1 23 254 276 254 276 0.98

3 5 1.4e-06 0.00012 22.6 2.3 1 23 282 304 282 304 0.99

4 5 6.3e-07 5.1e-05 23.8 1.1 1 23 310 332 310 332 0.99

5 5 0.00034 0.027 15.2 1.9 3 22 340 359 338 362 0.84

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	5	2.3e-05	0.0018	18.9	0.1	2	23	227	248	226	248	0.97
2	5	6.8e-09	5.5e-07	30.0	0.0	1	23	254	276	254	276	0.98
3	5	1.4e-06	0.00012	22.6	2.3	1	23	282	304	282	304	0.99
4	5	6.3e-07	5.1e-05	23.8	1.1	1	23	310	332	310	332	0.99
5	5	0.00034	0.027	15.2	1.9	3	22	340	359	338	362	0.84

Sequence Information

Coding Sequence: ATGCCCGAGTACGTGCTGTGCAGGATCTGCTTGACAGAGGACATCAACTCGGAGGCGATGGCGCCCCTGTTCGATGACGAGGACGCCCAGTGCCGGGAGCTGGTGCGCAAGATTGAGGAAGTGGGCAGCATCAAGCTGGTGCCGCTGCAGAACATTCCGAGCATGCTGTGCTACAGCTGCGTGGAGCGGCTGACCAGTGCCCACAAGTTCCGGGAGCTTTGCCAGGAGAGCGAGCGGACGTTTGCCACGAATGTGGTCAAGGCCGAGATGAAGTCGGAGCCAACAGACGAAGTGGCACACATTGTGGCGGATCACATAGAGTACATCTACGAGTCGGCCAACGACTTCATAGACGGCGTGGAGGAGGACATCGAGATGGAGAACATGTTGGAGGAACGCCTAGAGGACGGCGTTGCGGATACAACCGAGTCCTTCGAGATTAACACCGTGGTGGACGAACTGGACGACAACGAGCTGCTGGTGCCGAATAGCGCTGATAGCGACTACGAGCCCAGCGAGCGCTGCCGCAAGCCCAAGGTGCGGAAGACGCGGATGGGTAAACGTGGACGTGGTCGACCCCGCGGCTCTGGCTCTGGACATCCACGCAGCCCTAGCCGGGAGCGACCGACTGTGCACTCCAGTTGCAAGTCCTCGCCCGAGCAGTCCTCCACAAACATTATGTGCGAGATTTGTGGCAATATCTACTCTAAGCGAGCGGCGCTCAACATTCATATGCGTCGTCACATGGCCGACAAGCCATTTGAATGCGAAATCTGTGGCAAAACCTTTGCGGGTCCATCCGAGCTAAATCGTCATATCCGAGTGCATACAGGCGAGAAACCCTTCACGTGTAAATACTGCAATCGCTCGTTTGCGGACCGCAGCTCTAACATTCGGCATGAAAGAACTCACACGAACGAGCGACCCTTTACATGTTCCACCTGCGGCAAGGCCTTCTCCTACTCCAATGTGCTAAAAAACCACATGCTCACCCACACGGGCGAGAAACCCTTCCTTTGCCGGCCGTGCAATAAAACCTTCTCCCGCAAGCACCAACTGGAGCAGCATATCGGCACTATGACCCATCAGCAGACTGTTAGGAACCACCAGACTAACGACCACCAGCGGCACTCAGAGATCTACTAG
Protein Sequence: MPEYVLCRICLTEDINSEAMAPLFDDEDAQCRELVRKIEEVGSIKLVPLQNIPSMLCYSCVERLTSAHKFRELCQESERTFATNVVKAEMKSEPTDEVAHIVADHIEYIYESANDFIDGVEEDIEMENMLEERLEDGVADTTESFEINTVVDELDDNELLVPNSADSDYEPSERCRKPKVRKTRMGKRGRGRPRGSGSGHPRSPSRERPTVHSSCKSSPEQSSTNIMCEICGNIYSKRAALNIHMRRHMADKPFECEICGKTFAGPSELNRHIRVHTGEKPFTCKYCNRSFADRSSNIRHERTHTNERPFTCSTCGKAFSYSNVLKNHMLTHTGEKPFLCRPCNKTFSRKHQLEQHIGTMTHQQTVRNHQTNDHQRHSEIY

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00486758;
90% Identity: iTF_00515736;
80% Identity: -