Basic Information

Insect: Drosophila lutescens
Gene Symbol: gfi1b
Assembly: GCA_037075285.1
Location: JBAMCF010000316.1:1469356-1471390[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 8 5.3e-06 0.00043 20.9 0.6 1 23 297 320 297 320 0.95

2 8 3.7e-05 0.003 18.2 1.3 3 23 332 352 331 352 0.99

3 8 2.2e-06 0.00018 22.0 1.2 2 23 362 384 362 384 0.92

4 8 1.7e-05 0.0014 19.3 0.2 1 23 390 412 390 412 0.97

5 8 3.7e-05 0.003 18.2 1.2 1 23 418 440 418 440 0.97

6 8 0.0008 0.064 14.0 1.0 1 23 445 467 445 467 0.98

7 8 8.7e-06 0.0007 20.2 0.7 1 23 473 495 473 495 0.97

8 8 0.0045 0.36 11.7 4.1 1 23 501 524 501 524 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	8	5.3e-06	0.00043	20.9	0.6	1	23	297	320	297	320	0.95
2	8	3.7e-05	0.003	18.2	1.3	3	23	332	352	331	352	0.99
3	8	2.2e-06	0.00018	22.0	1.2	2	23	362	384	362	384	0.92
4	8	1.7e-05	0.0014	19.3	0.2	1	23	390	412	390	412	0.97
5	8	3.7e-05	0.003	18.2	1.2	1	23	418	440	418	440	0.97
6	8	0.0008	0.064	14.0	1.0	1	23	445	467	445	467	0.98
7	8	8.7e-06	0.0007	20.2	0.7	1	23	473	495	473	495	0.97
8	8	0.0045	0.36	11.7	4.1	1	23	501	524	501	524	0.96

Sequence Information

Coding Sequence: aTGTCGAGGATTCTCGCATCAACAGAAGCCGCCAAAGGAGATCCAACAAATTGGCATCAATGGTATCAATCAAACTCCTGGACCAGCATGCTGGCGATGACCGTTGGCAAATACTTCTGGGTGGATATCAAAAAGGAAGATGAGCTAAGTAATTATCTGTGCTCGGAGTGCTTTACTTTAATGGATTGCCTCATTGAATTCTCGGAAAGAGTTCGCAAAGTACAGACCCTATTCAACAGATTGCAGAACTTAAACCCGGATATGAATATGATCTTAAACTATGAGGAATTACGAGCGGACTGCGGCTTGGCCAGCGATGAATGGAAGCATATGATGTGCCGAGCAGTGGTACATCCTCTGCCAAAAGAAGAGGAATTCATTGATGAGGTCGAACCAATAGCCATAGAGGAACTAAGAACCGACGATATAGAAGAGCAAGTCTTAATCATACCCACTTTAGTGGAAGAACAGCAACCACTGCAAAAAGAAGAATTTGTCGAAGAACTAGATATCCCTGGAGAAGATCTGCAAGTCGATGGAATGGAAACGGAAATCCTCGAGGACGAAGGTGAACACCTGGCGGAGGAAGAGGTTGAAActgtggaggaggaggtggaacACCAGGACACCTCCGAGTGCCTAGTTGAAGTGGAAGACATCCCGGAGGAGGACTACATCGAAGAGTCGCAAATAATCGAAGAAAGCCAAGTTCAAGATTTCCGCATTGAAACGTTTGAAATAATATCCCAAGGCCCCCCTCAAAAAGAACCCTCAAAAACTGAAGCTACTGAGGAAACAATAGAGTCCGAAGACGACACCCAGGAAGATCTCTCATCTGAGCATCTCATAGAAGAAGACGAAGATGAAATTCCAGATGAGCCAGCCATTTACAAATGCAGCATTTGCAACAAGCCGTACAAGAAACCCAAGGCCTATCAGCGACACATGGAGGAAGTTCACAACACTGTGGCCAAAGATCTGCCAAAATTGTTATGCAACCAGTGCGGTCTGTGCTTTCCCACGGTCGCCCAGCTAACCTCCCACTACCGAACCCATTTACCCGCCAAGGTGAAGTCCGATAACTCCTGTCCGCACTGCGAGAAACGTTTCACCACCTCGGGAACACTCAAGCGACACATAGAAGGGGTTCACCAGCAGATCAAACCCTATGTCTGCGACATTTGCGGCAAGAGCTTCAACTACATCACCGGACTGAAGGATCACAAGCTGGTTCACACCGAAGAATGCCCCTTCGAGTGTCCCGTGTGCAAGCGACGCTTCAAAAACAAGGCTAGATTAAAGATCCATTCCGATACTCACAGTGCTCAAATTTACGAGTGTGCCATATGCGGCTTGAAGCTCAAAACCCGTCGAACATTTAACAAGCACAAATTGGTCCACTCAGATGAACGCCAGTATAAATGCGATGTCTGCGGCTCGGCGTTCAAGCGGAGTAAGACACTAAAGTCGCATCTTATCCTGCACACTGGCATCCGGCCTTATAAGTGCAACTTTTGCGGCAGGGACTTCTCAAATGGCTCCAATTGTCGATCGCACAAGCGGCAGGCGCATGCCAAGGAGCTGGCCGAGGAGGAAGCACGCGGTGTGTCGCGTTCCACTCTACTTCCTTTGCTGGATGAACTTACCAAGGCgtcaaagcTCATAAAAACACCGGCAAAGCCCAGCAAAACGAAGGGAAGCAGGCCAAAAGTTGATCCTAATCCTGAATCTCCCACAAAGGACACTGATGGTGCCATCCTCTACGAACTTGTCGAGGAGGTTGAATACTCCTAA
Protein Sequence: MSRILASTEAAKGDPTNWHQWYQSNSWTSMLAMTVGKYFWVDIKKEDELSNYLCSECFTLMDCLIEFSERVRKVQTLFNRLQNLNPDMNMILNYEELRADCGLASDEWKHMMCRAVVHPLPKEEEFIDEVEPIAIEELRTDDIEEQVLIIPTLVEEQQPLQKEEFVEELDIPGEDLQVDGMETEILEDEGEHLAEEEVETVEEEVEHQDTSECLVEVEDIPEEDYIEESQIIEESQVQDFRIETFEIISQGPPQKEPSKTEATEETIESEDDTQEDLSSEHLIEEDEDEIPDEPAIYKCSICNKPYKKPKAYQRHMEEVHNTVAKDLPKLLCNQCGLCFPTVAQLTSHYRTHLPAKVKSDNSCPHCEKRFTTSGTLKRHIEGVHQQIKPYVCDICGKSFNYITGLKDHKLVHTEECPFECPVCKRRFKNKARLKIHSDTHSAQIYECAICGLKLKTRRTFNKHKLVHSDERQYKCDVCGSAFKRSKTLKSHLILHTGIRPYKCNFCGRDFSNGSNCRSHKRQAHAKELAEEEARGVSRSTLLPLLDELTKASKLIKTPAKPSKTKGSRPKVDPNPESPTKDTDGAILYELVEEVEYS

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00605749;
90% Identity: iTF_00605749;
80% Identity: -