Basic Information

Insect: Drosophila lutescens
Gene Symbol: -
Assembly: GCA_037075285.1
Location: JBAMCF010001083.1:2615538-2619077[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 18 0.15 12 6.8 3.8 2 23 326 348 325 348 0.96

2 18 0.86 70 4.5 0.1 1 23 355 380 355 380 0.90

3 18 0.036 2.9 8.8 2.2 2 23 391 412 391 412 0.93

4 18 0.2 16 6.5 0.6 2 23 452 474 452 474 0.94

5 18 0.0046 0.37 11.6 0.3 3 23 482 502 480 502 0.95

6 18 0.14 11 6.9 0.1 1 23 510 533 510 533 0.96

7 18 0.00057 0.046 14.5 0.3 2 23 538 559 537 559 0.97

8 18 0.16 13 6.8 0.1 1 20 567 586 567 588 0.92

9 18 0.0016 0.13 13.1 0.6 1 22 607 628 607 631 0.90

10 18 0.38 30 5.6 1.4 3 21 638 656 638 657 0.90

11 18 0.0099 0.8 10.6 0.5 1 23 676 701 676 701 0.96

12 18 0.25 20 6.2 1.3 2 23 719 741 718 741 0.93

13 18 0.00076 0.061 14.1 0.1 2 23 747 769 746 769 0.92

14 18 0.011 0.86 10.5 0.1 2 23 773 795 772 795 0.95

15 18 5.3e-05 0.0043 17.7 1.5 1 23 801 823 801 823 0.98

16 18 0.0092 0.74 10.7 0.9 1 23 827 850 827 850 0.93

17 18 1.6e-05 0.0013 19.3 2.0 1 23 856 879 856 879 0.97

18 18 2.5e-05 0.002 18.8 0.2 3 23 885 911 883 911 0.84

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	18	0.15	12	6.8	3.8	2	23	326	348	325	348	0.96
2	18	0.86	70	4.5	0.1	1	23	355	380	355	380	0.90
3	18	0.036	2.9	8.8	2.2	2	23	391	412	391	412	0.93
4	18	0.2	16	6.5	0.6	2	23	452	474	452	474	0.94
5	18	0.0046	0.37	11.6	0.3	3	23	482	502	480	502	0.95
6	18	0.14	11	6.9	0.1	1	23	510	533	510	533	0.96
7	18	0.00057	0.046	14.5	0.3	2	23	538	559	537	559	0.97
8	18	0.16	13	6.8	0.1	1	20	567	586	567	588	0.92
9	18	0.0016	0.13	13.1	0.6	1	22	607	628	607	631	0.90
10	18	0.38	30	5.6	1.4	3	21	638	656	638	657	0.90
11	18	0.0099	0.8	10.6	0.5	1	23	676	701	676	701	0.96
12	18	0.25	20	6.2	1.3	2	23	719	741	718	741	0.93
13	18	0.00076	0.061	14.1	0.1	2	23	747	769	746	769	0.92
14	18	0.011	0.86	10.5	0.1	2	23	773	795	772	795	0.95
15	18	5.3e-05	0.0043	17.7	1.5	1	23	801	823	801	823	0.98
16	18	0.0092	0.74	10.7	0.9	1	23	827	850	827	850	0.93
17	18	1.6e-05	0.0013	19.3	2.0	1	23	856	879	856	879	0.97
18	18	2.5e-05	0.002	18.8	0.2	3	23	885	911	883	911	0.84

Sequence Information

Coding Sequence: ATGTCGGAAAACGCGAAAAACAATAGCTGCCTGCATTGCAGCGTATTCAATACGAAATACCAGTACCAAGAAATATTCGACGAGTTCGGCATCGAACTGGGATTGCAATCCCTGCTGGCCAAGCACTTCCAGTTCGATGTATCCCCCGACCCACGGAAACCGCAGCTCCTCTGCGAAGTCTGCGTCAACAATCTCATTCGACTGTTCGACATCGATGAACTGGAGAGGGAAAGGGATGCGGCCAACAAGGAGGGTCAGGTCCAGGTCCAGCAGGAGGAACCAATTGTCATCCCCGAGGTCCAGGCAACACCGCCAGCTGCCAAACCTGTCAGGAAGGCAACAGCGTCAAAGCATCTGGCCAAGGTCCTGCGTCCTGCGCCCATTACTACCACCCGGGAACCAAGTGCCCGCATAAGGAATGCAATGGTTGCAGCTCAACAGATAACACCTAAACCATCTAGATCTCCTGCGCCAGCCAAGAGCCCTTCTCCGGAGGTGCCTCACACTAAAAGTGGGGCCAGGTTGGCTCCAAATAAGGGAGATCAGGAGCAGATCAATGCCCTGATGCAAAACATCCTGCAGGATGACGAGGCTATTGTTGACGGCGAAACCATTGTTGAAGAAGTGTCCTGTGAAGATCCCGTGAACCCCGGGGAAACGGAAACTGCTGGACAAATGGTTCTTCTAAACATCGAGCCCGTTGCAGAACCCAATTTGGATGAGGATGAATACATATACGAACACGAGGATATTTTGGATCCGAATTTGGAGGATGTGAATGTCAAACCATCCAGATTGATAGTGAAAGCAGAGGAAAGTCAAAGTGATGGAGAAATCGACGAAGTCGAGCACAGCCATATAGTACTCTTCAACTTTGTTGATATCAAAGAAAAGGATAACATTGATGATATTCCGGAATACTTGTCCACCGTGGTAAAGACCAGCTTCGAGAAGCTTACCTTTGAGTGGTGTACCGTATGCAAGCACTGCTCGCTTAAGTGTCCCACATTTGAAAGTCTTTTGAGTCACATTTTAAAGACCCATAAAACCCGAAAAGATGTCTATGAGTGTCCCATTGAAGGATGCACCAAGATGCTGAAAGGACGGCAATTCCTAGCCATGCACCTGGTTCTTTTGCACGCACCCGTGGCTGAAATTCCAATTTATGGAAGCTGTCCGGAATGTAAAATGACTTTTTCCAACATTTTGCAATATAACAAACATTCTTGTGCTCATATAATCAAAAAGAAACGAGGTATTCGCTTATTTTGTGAAATGTGCTCTCTGGAGTTTCCATCCTGGAAGCGCTTCAATTTCCACAACCAATTTCATCTGGAGAAGCATAGACCTCGCACTTGCTTCGTTTGCGATTTTGCCAGCACCAACATCGATGAACTTTTCCAGCATTTGCATTACGCCCATGAGCCAGCGGGCACCCTATTTTGCGACCTTTGCGACCGCACTTTTCGGGACCCCGCAGTTTTCATGGAGCACAACAAGTCGCATGCTAATGTGAGCAGCACAACATACTCTTGCGGGGAATGCATGGCGAACTTTGAGTCGCGTGGTCGATTAAATGGACATATGAGGGCTATGCATGGCAGCGTTATAAGCTGCGAGCTCTGTTCTCGCGAATTCGCCACCGAAGCCACCTACAACATTCATATGAAGAAGCATCTGATCACCGAACGGGATGTTCATGTGTGCAGTTATTGTGGCCTGCTAAGTAACAGCAGCGAAACCCTACTTGCCCATGTGGATACCGTGAATTCGCCTTGCTTTGGTACCAAGATAAACACAGAACTCCTTCAGAATGCTTACGTCTGCGAGTACTGCACCTcgtactttaaaaaaaaggtaaatttgCAGGCCCATCGGGACTCAGGTGTTCATAAGGATGGACTGTATTGGTGCCAGCCGTGCGGCAAAGACTTTCCCCACATGAAACTGTACCGCCATCACCTGCGCAACTACCAACAGCTTCGCACGGACTCGACTCATCGCAAGCTTGAGCTTTGTGTGTATTACATGTGCGATCAGGAGAACTGCTCAGAGGCCTATGTAAACTGGAACTCCTTGTACACGCACAAGCGACGCACTCACGAATCCTCGAATAAGCAGGCGGAGAAGACCGCCAAGACTACCCCAGAATGGATTTGTCAGTTTTGCCTTAAGGAATGCCGCTCAAAGATGTCCTTGTCTGTGCATGTGGCAAGGAGCCACAATAATGacaaCGTGGTTTGTCCTTTGTGCAATGCTTCATACAAAAGCCAGGATGCTCTGGCCAAACATCATGCCTATTGGCACGAACCCATTGAGTGTCCAGAATGCTTTAAAATCGTCAAAAATCGAAGGAATTATGACACTCATGTAAATGTGGTGCATTCGAATAAAAAGCGCTATTCTTGCGGTGTCTGCCAGAAGGGTTTTTATCACAAAAGCGAAATGGAGGCACATCAGAAGCTTCATGGACAGTCTTACAGCTGCGAGCAGTGCAGTTTCACGACCAGGAACAAGAAATCGCTTTCTGTTCACGTTCTTGGTCAGCACTACAAGCGTTTTGCTTTTGAGTGCAAGGTGTGCAAGAAGAGGTTCGGACGTCGGCAGGGCCTGAATACCCACATGCAGCGATCTCACGGTTCCAAGTACATGTGCCGTGATTACTTCGAGGGCGGCTGTGGACGCACCTTTGTAAACAGTTCCCAGTTGAATGTTCATGTGCGTAGGATGCACAAGGGAATTATTTTGCTTCAAGAAGATGTGGTCGAAGAGGATGAATATGTCGGTGACGATAATCCAACGACATCCAAAAAGCGCTGCCTTCGTATCAACGAAGACAATATTGAGTTTATAGAAGAAGCCGGAGATGATCCAGATGGTGTAGATTTGGAAGAGGGagtcgaggaggaggacgagtaTATCGACGAGATACCAGAGGAAGACACTAAGAATTGA
Protein Sequence: MSENAKNNSCLHCSVFNTKYQYQEIFDEFGIELGLQSLLAKHFQFDVSPDPRKPQLLCEVCVNNLIRLFDIDELERERDAANKEGQVQVQQEEPIVIPEVQATPPAAKPVRKATASKHLAKVLRPAPITTTREPSARIRNAMVAAQQITPKPSRSPAPAKSPSPEVPHTKSGARLAPNKGDQEQINALMQNILQDDEAIVDGETIVEEVSCEDPVNPGETETAGQMVLLNIEPVAEPNLDEDEYIYEHEDILDPNLEDVNVKPSRLIVKAEESQSDGEIDEVEHSHIVLFNFVDIKEKDNIDDIPEYLSTVVKTSFEKLTFEWCTVCKHCSLKCPTFESLLSHILKTHKTRKDVYECPIEGCTKMLKGRQFLAMHLVLLHAPVAEIPIYGSCPECKMTFSNILQYNKHSCAHIIKKKRGIRLFCEMCSLEFPSWKRFNFHNQFHLEKHRPRTCFVCDFASTNIDELFQHLHYAHEPAGTLFCDLCDRTFRDPAVFMEHNKSHANVSSTTYSCGECMANFESRGRLNGHMRAMHGSVISCELCSREFATEATYNIHMKKHLITERDVHVCSYCGLLSNSSETLLAHVDTVNSPCFGTKINTELLQNAYVCEYCTSYFKKKVNLQAHRDSGVHKDGLYWCQPCGKDFPHMKLYRHHLRNYQQLRTDSTHRKLELCVYYMCDQENCSEAYVNWNSLYTHKRRTHESSNKQAEKTAKTTPEWICQFCLKECRSKMSLSVHVARSHNNDNVVCPLCNASYKSQDALAKHHAYWHEPIECPECFKIVKNRRNYDTHVNVVHSNKKRYSCGVCQKGFYHKSEMEAHQKLHGQSYSCEQCSFTTRNKKSLSVHVLGQHYKRFAFECKVCKKRFGRRQGLNTHMQRSHGSKYMCRDYFEGGCGRTFVNSSQLNVHVRRMHKGIILLQEDVVEEDEYVGDDNPTTSKKRCLRINEDNIEFIEEAGDDPDGVDLEEGVEEEDEYIDEIPEEDTKN

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00605739;
90% Identity: iTF_00581702;
80% Identity: -