Dlut001384.1
Basic Information
- Insect
- Drosophila lutescens
- Gene Symbol
- -
- Assembly
- GCA_037075285.1
- Location
- JBAMCF010000051.1:385885-387207[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 10 0.00088 0.071 13.9 2.1 2 21 142 161 141 162 0.95 2 10 0.00073 0.059 14.1 7.3 1 23 167 189 167 189 0.99 3 10 8.2e-07 6.6e-05 23.4 0.2 1 23 195 217 195 217 0.98 4 10 5.1e-05 0.0041 17.8 1.9 1 23 224 246 224 246 0.98 5 10 0.002 0.16 12.8 1.7 1 23 249 271 249 271 0.98 6 10 1.1e-05 0.00085 19.9 0.5 1 23 280 302 280 302 0.98 7 10 0.0021 0.17 12.7 1.1 1 23 308 331 308 331 0.95 8 10 1.3e-05 0.001 19.6 1.0 1 23 336 358 336 358 0.98 9 10 0.00019 0.015 16.0 0.6 1 23 364 386 364 386 0.97 10 10 1.5e-05 0.0012 19.4 0.2 1 23 416 438 416 438 0.98
Sequence Information
- Coding Sequence
- ATGGAGTCTATAAAGGAGGAGTTCCTGGACGAAGACCAGCTCGTGGAAGAAGTATTCGATTCGCCAGAAAACTACAAAGTTGAAGAAATATCCTATAGTTTTGACTGCCAAGTTAAGGAGGAGTTTATTGAAGAGCCCTGTGGTCACCAGTTCCAAGTCAAGAAGGAATCCCCTGAGAAGGACATTATATCATCTGTAGACAGTGGGAGATTCTATAATGCCGCAGACTTCCAAGTCAAGAGAGAGGCAACCGATGAAGGcgaatccgaatcggaatcCCAGCCGTTTTTAGACCAAATAAAGATCGAACCCGTTGAATTCAGCAGCATAACAGACGGTTCCATGGAACAGTCCACTATTCAAGATGATAGTGACCTTGAAGACGATTCGGATGAAGAGGAGGCGGAAGAGAAGGTGCCCGTCAAGTGTTCCCACTGCCAGAAGCTCTTTTCGCACAATGGACGTCTTCAGATACACCTGCGGAACCTTCAGAACCCATACAAATGCGATCGGTGTCCCAAGACCTTTATGTTAAAAGGACATTTTCATCGACATCAGCAGAAGCATGACGACGAGTGGATCTACGAGTGTCCGTACTGCCCGCAAGTTTTGAAATCGAAGGTGAACTTCGAGCGACACATGCAAATTCACACGGACGAACGGCGCCCCTTTAAGTGCGATCATTGCCCAATGGCATACGAAAGTCATCGGTGGCTGGCAAGACACATGCTAAGTCATGACCTGTACCAGTGTTCCCACTGCCCGAAGGCCATGCCATCAAGATTGCACCTGGTTCAACACCTTCTAAGTCACAGGGAAGAGAGGAAAGACACCACCCACAAGTGTGACGTCTGTCCGCTTGCCTTTGGGAAGCGCAGCGATCTCAAGAGCCACATGGCAATGCATTCGACAGAAAGACCCTTCGCTTGCTCCCACTGCCCCATGAAGTACCGCCTGCGGGGCAGCCTGTTGGCACACCAGCTGAACCGGCACACGGAACCACAGTTCAAGTGCTCCCAATGCTCGATGGCCTTCCGACTTCAGGGTTCTCTGACGCAACATATGCGAGACCATACGAAAGATCGACGCTATAAGTGCTCCCTCTGCCCGGAAACCTTTGGACATGCTGCCGGTCTGCGGACGCACTCGAAGGAGCACACAGGAGATCAGTGGTTCGGGTGTGCCGAATGTTCGCAGAACGGTGTGCTAGCGAAACACAAGTCAGCCTGCACAAACGATCGACTCTACAAGTGTTCCTTCTGCCCGCTAACTTTCGCACAGGCTGCCAGTCTAAGGACGCACGCAATAACGCACATGGCTTGA
- Protein Sequence
- MESIKEEFLDEDQLVEEVFDSPENYKVEEISYSFDCQVKEEFIEEPCGHQFQVKKESPEKDIISSVDSGRFYNAADFQVKREATDEGESESESQPFLDQIKIEPVEFSSITDGSMEQSTIQDDSDLEDDSDEEEAEEKVPVKCSHCQKLFSHNGRLQIHLRNLQNPYKCDRCPKTFMLKGHFHRHQQKHDDEWIYECPYCPQVLKSKVNFERHMQIHTDERRPFKCDHCPMAYESHRWLARHMLSHDLYQCSHCPKAMPSRLHLVQHLLSHREERKDTTHKCDVCPLAFGKRSDLKSHMAMHSTERPFACSHCPMKYRLRGSLLAHQLNRHTEPQFKCSQCSMAFRLQGSLTQHMRDHTKDRRYKCSLCPETFGHAAGLRTHSKEHTGDQWFGCAECSQNGVLAKHKSACTNDRLYKCSFCPLTFAQAASLRTHAITHMA
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00581678;
- 90% Identity
- -
- 80% Identity
- -