Dlut007213.1
Basic Information
- Insect
- Drosophila lutescens
- Gene Symbol
- -
- Assembly
- GCA_037075285.1
- Location
- JBAMCF010000352.1:863513-865993[+]
Transcription Factor Domain
- TF Family
- THAP
- Domain
- THAP domain
- PFAM
- PF05485
- TF Group
- Zinc-Coordinating Group
- Description
- The THAP domain is a putative DNA-binding domain (DBD) and probably also binds a zinc ion. It features the conserved C2CH architecture (consensus sequence: Cys - 2-4 residues - Cys - 35-50 residues - Cys - 2 residues - His). Other universal features include the location of the domain at the N-termini of proteins, its size of about 90 residues, a C-terminal AVPTIF box and several other conserved residues. Orthologues of the human THAP domain have been identified in other vertebrates and probably worms and flies, but not in other eukaryotes or any prokaryotes [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 7 3.3e-15 5.6e-12 46.5 0.1 1 86 102 171 102 172 0.83 2 7 1.1e-09 1.9e-06 28.8 0.2 1 62 199 256 199 272 0.78 3 7 2.3e-12 3.9e-09 37.4 0.4 1 87 275 346 275 346 0.80 4 7 2e-16 3.3e-13 50.5 1.0 1 85 369 440 369 442 0.80 5 7 3.1e-06 0.0052 17.8 0.5 1 58 475 524 475 544 0.80 6 7 3.5e-11 5.9e-08 33.6 1.7 1 87 562 631 562 631 0.80 7 7 3.6e-15 6.1e-12 46.4 0.6 1 86 723 795 723 796 0.82
Sequence Information
- Coding Sequence
- ATGGAAAAAATTCAGGTGAAAGATGAACCGCAATCGGCGGACGAGGACTTTcaaatggaggaggaggagatccaaataaaaatggagCCCTTAATGAATGAGGAAGCCCAATCAGACGAGGATACCTCGATGCAGGAGGAGGTCCAAATTAAAATGGAGCCTCTGATTAAAGAGGAGGCCCAATCAGACGAGGACTCTTCGGTGCAGGAGGAGGAATACTCTGATACAGAGTATGCTCCGTTTCAGGGTAAAGTTAAACAAGAACCAGAACTTTCAACTGGCATTCAGCTCGGGGATGCGACCTGTTGTATACCCAATTGTGGGCAGAAGGAGACCAGTGACATCCGTTTGTTCCGCTTTCCCAGCGACGAGGAGTTCCTTGTTCAGTGGCTGGTGAACACCCAAGTGAAGCCTCGCCTGGTTAATCCCCCAGACCTTTATGTGTGCCAGCTCCACTTTGAACCGGAAGTTATAAGCGGAACCCAGCTTGCGACCTGGGCCCTGCCCACTTTACGCCTTGGCCACGAAGATTATTTGATAACGTCTACCGTGCAGAATTCTGAGCCGGTGATGCGGTACATCCGCGCGCACTACTGCTCCGTAATCAGCTGCTTTCGCTCCGAAGACGATGGATTGCGGCTATTCGAATACCCAGACGATCCGGAAACTTTCCTAAAATGGAGGCAAAAGTGCCGTCATGACCCTGTGCAAATTCATAGATTCGGCTTTCGCTTGTGCGCGTCGCACTTTTCCACCGACAGCTTCGATCCGGATACTGGCGACTTGTTTGCGGGATCGCAGCCAACTAGGGAGCTGTTCCCGTGCGTGGTCCGGGGATGTGTGCGTGAGGAAGGTACTCCGGTCAACTACTTCAAAGTGCCCCATAACACCGCCAAAGCGGAGGCTTGGAGCCACAACCTGTACATTCCTTTGACTGCCATCAACCGGACTCTGCCACGCGTTTGCAGCCGACACTTCGAGGACGCCTGTTTTACGGAAAAGAAATCACTTCGCTGGGGTTCGCTGCCCACTCTATTCTTGGGTCATGACAACGAAGTCCTGCCCAATCCGGAAAGAATACGATTTCAAGCTGAAGGCATTCCTTGCTGTGTGCCCGGCTGTGGACGCCACCGGACGGCGAGGGACCGTTCGTTTTCTTCGTTTCCCAAGGACAGGGGTCTGGTCAGAAAGTGGATCCACAACATTCGACTGGAAGTCAGCTTTAAAGAAGTGCCAGGCCTGCTGATATGCCGTGAACACTTTGAGGAGAGCTGCTTTAAAAGTGGTGCGAAGTACCTGCGCTGTGGTGCCATGCCAACCCGAAAGCTCGGTCATCCCCATAGCGACCTGTTCGAGTCCGATTATACTATCTCATCCAAATCCACATCTGGTTCGGTTGTGTTTAGAAAGAGGAGAGTCAGGTGCTGCCATCCAGGCTGTGGGCGGCATGAGACGATTGTTAACGATCTACCGCGGATGGACGAACTGCACAAGGCTTGGCTGAAGCACATGAACATTAAAGAAATCCCTGCTGACCCCAAGAAGGCGCCACAGCTATGTGACATCCACTTTATTATCATGTACGAGCACAGTGTCAAGAACTTTTCCGAACATGCTCCCGACAAAATTCTAGACACCAAATACAAGTTGGTCCGGAATAAATATACTATGCAGGCCTTGAGTTGTTCCGTCAAGGGATGCGATACCTTTATTCCCAGAGATGATTACATCCTGCACAGTATGAGAAAGGTCAAGGAACTTCAGACGATGTGGGTGGAAAACGGTCAGATAGATTTTAGCTCGCGAAGTCGCATTCGGGTGTGTAATAAGCACTTTGAACCgaaatgtttcaaaaatcGTCGTCTGCACGCATGGAGTGTGCCCACATTGAATCTGCCGGGAGAGGCAATCCATCAGAATATTACCGAAGAGCAGTGGAGTATCTACAGTCAGTCGGCGAAACAGAGTGAGGTgaaggaagaagaggaagttCAGTACTCGGATTCAAATTCCATTGACGGAAAAAGCAGCCCCGTCACGTTCGAGGAGGAGCCCAAAGATCAGACCCTGGAAGTGGTTCTCGAAGTGGCCCCGAATCAGAAATCCTACCCAGAACAGACCACCGAGGAGATCCTCTCCAAACCGAACAAGTTCAATGTCAATCGCTGCGCCGTTCCGGGATGCCGGATGACTTTTAGGGATGTCAACAGAAAATTCCGGCTCCACAAACTGCCCGATTCCGATGATACCGTCGCGAAGTGGCTGTATAACACCCAGATAAAGGTGGCCAATGAGCACTGGCCCAGCATTCGCATCTGTGCCCTACATTTTGAGCAGGATTGCTTTCAAGGATCCAGGTTGAGGCCGGGAGCCGTGCCCACGCTTTGTTCGGCAGGTAATTCACTGGAATGGATGCACCAAAGTGAGTGGAGGATGAGGAAAAACACACGTCCGACCCGATTTCCAAGGCCACCAAACTGA
- Protein Sequence
- MEKIQVKDEPQSADEDFQMEEEEIQIKMEPLMNEEAQSDEDTSMQEEVQIKMEPLIKEEAQSDEDSSVQEEEYSDTEYAPFQGKVKQEPELSTGIQLGDATCCIPNCGQKETSDIRLFRFPSDEEFLVQWLVNTQVKPRLVNPPDLYVCQLHFEPEVISGTQLATWALPTLRLGHEDYLITSTVQNSEPVMRYIRAHYCSVISCFRSEDDGLRLFEYPDDPETFLKWRQKCRHDPVQIHRFGFRLCASHFSTDSFDPDTGDLFAGSQPTRELFPCVVRGCVREEGTPVNYFKVPHNTAKAEAWSHNLYIPLTAINRTLPRVCSRHFEDACFTEKKSLRWGSLPTLFLGHDNEVLPNPERIRFQAEGIPCCVPGCGRHRTARDRSFSSFPKDRGLVRKWIHNIRLEVSFKEVPGLLICREHFEESCFKSGAKYLRCGAMPTRKLGHPHSDLFESDYTISSKSTSGSVVFRKRRVRCCHPGCGRHETIVNDLPRMDELHKAWLKHMNIKEIPADPKKAPQLCDIHFIIMYEHSVKNFSEHAPDKILDTKYKLVRNKYTMQALSCSVKGCDTFIPRDDYILHSMRKVKELQTMWVENGQIDFSSRSRIRVCNKHFEPKCFKNRRLHAWSVPTLNLPGEAIHQNITEEQWSIYSQSAKQSEVKEEEEVQYSDSNSIDGKSSPVTFEEEPKDQTLEVVLEVAPNQKSYPEQTTEEILSKPNKFNVNRCAVPGCRMTFRDVNRKFRLHKLPDSDDTVAKWLYNTQIKVANEHWPSIRICALHFEQDCFQGSRLRPGAVPTLCSAGNSLEWMHQSEWRMRKNTRPTRFPRPPN
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00581564; iTF_00578572;
- 90% Identity
- -
- 80% Identity
- -