Dlow014191.1
Basic Information
- Insect
- Drosophila lowei
- Gene Symbol
- -
- Assembly
- GCA_008121275.1
- Location
- CM017781.1:56443147-56445287[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 8 1.9 1.4e+02 3.1 0.4 3 23 285 306 283 306 0.87 2 8 0.00063 0.047 14.0 1.5 1 23 369 391 369 391 0.97 3 8 6.9e-06 0.00051 20.2 1.0 2 23 399 421 399 421 0.96 4 8 0.00013 0.0094 16.2 0.7 3 23 430 451 428 451 0.93 5 8 0.01 0.78 10.2 0.3 2 23 460 481 459 481 0.97 6 8 0.023 1.7 9.1 1.6 1 23 490 512 490 513 0.96 7 8 2.3e-05 0.0017 18.6 0.6 1 23 518 540 518 540 0.98 8 8 0.017 1.2 9.6 8.2 1 23 546 569 546 569 0.97
Sequence Information
- Coding Sequence
- aTGATGATATGTCGACTCTGCCTGGAGGATACAGAGCACAGTGTGCCCATCTTCGATCAGGATGGAGGAGCCGTGCATCACACGATGCAGCAGCTGGCGGAACTGATAGAGAAGCATCTTCAGTTGGTGCTTGCGGCCAATGATGCGGTGTCCACTTGCCTGTGCGCCACATGCTGGCAGCAGCTGTCCAGCTTCGAGCAGTTTTGCATCATGGTGGCGGACAAACAACGCGCATTGCAGCTTAAGATCGAGGTCTCAGATCCAGAGCCGGAACCGGGTCTTATCGTGTGGAATACTGAGTCGCCTATTGAGTCGAAGATCGATTTCGATGGCGGTGATATTAAGGACCACATTTTGTGTGAGCCCGTCATCGACGCTATGGCCGCCAGAGACGATAAGGATGATGATAGTGTTGATGGCGACCGATTTGAGACGGACTTCGAGCCCAACGCCATCGAGCCAGATCCTGTAAAACCTAAAAATCCAGGTAGGGGCAGGCCCCGTAAAACTCTCCAAAAGGATTCCCAGCTCATCAAAAAGAAATACGAGAAGCACAAACAGACAAGGGCGGGCTTCACTGGACTTACACTCCGCGAATCCCGAGCACGTGCCCGCGATCTTAGACGTAAACCAGAGGCTGATTCATCAGGCAACGACTCGACACCTCCGGACCCGGAGTACACACCCAGCGTGCCGACCCGTGCCAGCGGAAATCGTGGCCGTCCCAAGACTATAACTAAGTGCCAGAGAAAGCATCCAACTGTTGAGGTCGCAGCTGAAACTGAACCTTCTGTGAAGCGTAACAGCATCAAGGAGATGGACGACTTTATAGCGGCCAATGTGAAGCTCGATTGTTGCCTGTGCGCGGCTCCCCTTGAGGACTTTAACGATCTGAAGCGACACTTTCGAGTGGAGCACAATATCCTGGGGTACGTGAAGTGCTGCAACAATCGGTATAAGAAGCGCACTCTGTACGTGGACCACCTACACTGCCACAAGGACCCGCAGTACTTTAGCTGTCAGCCCTGCCGCAAGAACTTCCTGAATCGCAACAGCCAGGTCATGCACATGCTTCGCTTCCACTCCGAACAGCAGGAGCTGGTGCATCAGTGCTCCATCTGCGAAGCACGGTTTGCCAAGAAATTCCTGCTGACTATGCATCTGAAGGGTCACAAGGGCACCGAGCGTCCCGAGGTCTGCGACACCTGTGGCAAGACATTCCGCACCAAATTTGAGCTGAGCGCCCACGAGAAGCGAATGCACGCGGCGGACTTCACCCCGATCATCTGTGACATCTGTGGTACGCATTTCCGTTCAAAGGCCAACTTTCTCATCCACAAGAAGGCACTCCATCCAGATGGGCCCGTGGCGGAGGTGCAGTGTACCCTGTGCGGCCGCTGGCTACGGGACGAGCGGAGTCTCCGCAAGCATCTGGCACGACACGATGATCGCGACAATCAGAATAAGTATCGCTGTTCCCTCTGCAACGCGGAGAAGTCTTCTCGTGCCGCACTCAGCAGCCACATGAGGTACCATCACTCCGCCAAACGGCACAAGTGCAGCCTCTGCGACAAGGAGTTCAAACTGCCACGCGCCCTCGTTGAGCACATGGCCACGCACACCGGAATCGATCTGTACTCGTGTCAGTTCTGCACTCGCACATTCAAGTCTCACGCCAACATGCACAACCACAAGAAGAAGATGCATCCAAATGAGTGGGTGCGCAAGTATTCCCAGCCCACAACCATTTCCGCTTTGGGTTCCTCCTCAGGCCATCTCTCCAGTacagaggcggaggcgggggcagagacagaggcagttGTTGGGGCGAATCTTCCGGCGCCGGCCACCAACTTAATGGATGACCCATCCGTTGGAGAGACCTTTGAGCTGCTCAGCAACAGCTCCGCATGCCCCACGCTCGACTGA
- Protein Sequence
- MMICRLCLEDTEHSVPIFDQDGGAVHHTMQQLAELIEKHLQLVLAANDAVSTCLCATCWQQLSSFEQFCIMVADKQRALQLKIEVSDPEPEPGLIVWNTESPIESKIDFDGGDIKDHILCEPVIDAMAARDDKDDDSVDGDRFETDFEPNAIEPDPVKPKNPGRGRPRKTLQKDSQLIKKKYEKHKQTRAGFTGLTLRESRARARDLRRKPEADSSGNDSTPPDPEYTPSVPTRASGNRGRPKTITKCQRKHPTVEVAAETEPSVKRNSIKEMDDFIAANVKLDCCLCAAPLEDFNDLKRHFRVEHNILGYVKCCNNRYKKRTLYVDHLHCHKDPQYFSCQPCRKNFLNRNSQVMHMLRFHSEQQELVHQCSICEARFAKKFLLTMHLKGHKGTERPEVCDTCGKTFRTKFELSAHEKRMHAADFTPIICDICGTHFRSKANFLIHKKALHPDGPVAEVQCTLCGRWLRDERSLRKHLARHDDRDNQNKYRCSLCNAEKSSRAALSSHMRYHHSAKRHKCSLCDKEFKLPRALVEHMATHTGIDLYSCQFCTRTFKSHANMHNHKKKMHPNEWVRKYSQPTTISALGSSSGHLSSTEAEAGAETEAVVGANLPAPATNLMDDPSVGETFELLSNSSACPTLD
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00603665;
- 90% Identity
- iTF_00518023;
- 80% Identity
- -