Basic Information

Insect: Drosophila lowei
Gene Symbol: -
Assembly: GCA_008121275.1
Location: CM017777.1:42777460-42778793[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 5 0.004 0.3 11.5 6.3 2 23 216 237 215 237 0.96

2 5 3.3e-05 0.0025 18.1 1.1 1 23 243 265 243 265 0.96

3 5 0.00013 0.0095 16.2 0.7 1 23 271 294 271 294 0.96

4 5 8.4e-08 6.3e-06 26.2 0.4 1 23 300 322 300 322 0.99

5 5 0.00048 0.036 14.4 1.6 1 21 328 348 328 349 0.94

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	5	0.004	0.3	11.5	6.3	2	23	216	237	215	237	0.96
2	5	3.3e-05	0.0025	18.1	1.1	1	23	243	265	243	265	0.96
3	5	0.00013	0.0095	16.2	0.7	1	23	271	294	271	294	0.96
4	5	8.4e-08	6.3e-06	26.2	0.4	1	23	300	322	300	322	0.99
5	5	0.00048	0.036	14.4	1.6	1	21	328	348	328	349	0.94

Sequence Information

Coding Sequence: AtggaaaaatcaaaaatatctCGAGATTGCCGCGCTTGCGGCAAGTTTATTTACAACGCGACATCCAAGAACCTCTTCCAAGAGCCGGACAACATAATGCTGAATCAAATTGAAGCCCTAACGGGCCTTTTTCTACTCGAGCAACCGAATTTCCCAGCCCGCATTTGCGGGCCCTGCGAGGTGTCTCTGAGGGAAGCCGTGCGCTTCCGAGAGCGTGTCATCCAGACGCAGAAGTTGCTTCAGAGCGGTTCCACCGAGCCAGAGGCTGTTGAGGAGATCTACTTGGACGCAACTGGACACAAGTCTAAGGAGGAAGCAGAAGAGGTGTCCGACTCTGATAGCGAGGAGAAAGACGACAGTCAATGTGTGGCGTCGGTAGAACTGGAACCCCTCGAAGAGGATGAGGATTCTGTTGGGGTGGCACCGGAAGATGTGACGCTTGATTCGACTCCTCCAGCTAAGCCCGGTACCGAAACGAACTCAAAACTCGCCAGATGCCAACCGCCCCCACGTGCCCCCACCGTATACGCATCGATGACGTTTGCGGACAACAGCAAAAGCCGGAACCTGCCACGCACCCAATGGGACAAGCTCAccgaggaggagacagtggcCCTGAAGCGGGAGCGCCGCAAACGAGACTGCATCTGCGAGCAGTGCGGCCGGCACTTCTCCTGCCCCAGCAATTTCAAAGTCCACCTGCTGCGGCACTCGGGAGTGAAGAACTTTGCCTGCGAGCAGTGTCCACAGACGTTCTATACGGCCCATCTTTTGCGGCGCCACGAGATGCTGCACCGGGGCGAGCGTCCGTTTCCCTGCCAGTACTGCAATATGTCATTCAACAACTCCAGCGGACGCATCCAGCACGAACGCATTCGCCACACCAACATCAAGCCCTACAAGTGCACGGAGTGCGACAAATCCTTTGCCGTGAGTGGGAAACTCAAGGCGCACATGCTTAGCCACACGGGCGTACGGTCCTTCCACTGCGAGCTGTGCAAAGTGTCGTTCATACGTCGCCCCCATCTACAGGCCCACTTCCGGTCGAAAAAGCCATGCCCAGAACTCGCATGCCCAGGAGTCCGCGGCCAAAGCATTGAAGTCGATGTTGAGACCCTTCTTCAGTAG
Protein Sequence: MEKSKISRDCRACGKFIYNATSKNLFQEPDNIMLNQIEALTGLFLLEQPNFPARICGPCEVSLREAVRFRERVIQTQKLLQSGSTEPEAVEEIYLDATGHKSKEEAEEVSDSDSEEKDDSQCVASVELEPLEEDEDSVGVAPEDVTLDSTPPAKPGTETNSKLARCQPPPRAPTVYASMTFADNSKSRNLPRTQWDKLTEEETVALKRERRKRDCICEQCGRHFSCPSNFKVHLLRHSGVKNFACEQCPQTFYTAHLLRRHEMLHRGERPFPCQYCNMSFNNSSGRIQHERIRHTNIKPYKCTECDKSFAVSGKLKAHMLSHTGVRSFHCELCKVSFIRRPHLQAHFRSKKPCPELACPGVRGQSIEVDVETLLQ

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00603611;
90% Identity: iTF_00484661;
80% Identity: -