Basic Information

Insect: Drosophila lowei
Gene Symbol: -
Assembly: GCA_008121275.1
Location: CM017779.1:9420350-9423388[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 7 0.032 2.4 8.6 0.5 1 23 149 171 149 171 0.97

2 7 0.02 1.5 9.3 0.1 1 21 177 197 177 198 0.95

3 7 0.01 0.78 10.2 0.6 2 23 547 569 546 569 0.93

4 7 2.4e-05 0.0018 18.5 0.2 1 23 671 693 671 693 0.98

5 7 2.7e-07 2e-05 24.6 1.7 1 23 699 721 699 721 0.99

6 7 1.2e-05 0.00089 19.4 1.8 1 23 727 749 727 749 0.98

7 7 0.00058 0.044 14.1 0.1 1 21 755 775 755 776 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	7	0.032	2.4	8.6	0.5	1	23	149	171	149	171	0.97
2	7	0.02	1.5	9.3	0.1	1	21	177	197	177	198	0.95
3	7	0.01	0.78	10.2	0.6	2	23	547	569	546	569	0.93
4	7	2.4e-05	0.0018	18.5	0.2	1	23	671	693	671	693	0.98
5	7	2.7e-07	2e-05	24.6	1.7	1	23	699	721	699	721	0.99
6	7	1.2e-05	0.00089	19.4	1.8	1	23	727	749	727	749	0.98
7	7	0.00058	0.044	14.1	0.1	1	21	755	775	755	776	0.96

Sequence Information

Coding Sequence: ATGCACGTGGATTTGACCATAATTAAGGAGGAAATCGACATTGATGACACTACGATCAAGCTGGAGGTGGAAGACAATGTGCCGGACGAGGCAATGGATGTTTCCTGTGCGAGTGGCGCCGTGAAAATTCTTGAGGAGCATGCTAATATGATAACGGTACCACTCAGTGATCACAAATCGGAGGACGAGCTCAAGTTTATAGCCAGCTTGGGTACGCTGGATGCCCAACAGTTATTCGCAGAACCGTCGCAGAATCAAAATGGATGTCCATACGAGTGTCACATTTGCCATTTACAACTACCCACTGAACTGGAGATCAAGGCGCACTTTGTTAACCACCAGATGAATCGTCACTTCTGTCGCCATGGATGCGGTGCCTGGTGCGGCACGCTGGAATTGGTGCTGGAGCACGAATATCGTCAGCATTCCCAGGGCATATACACGTTCTGCTGCAGGATCTGTGATTTAAGGGTTGATGGCGCCGATCGCTTGGCCAGCCATATGAAAAGCCACTGTTATGTGAATCGCTATGTCTGTGCCATATGCCGTCGTCCTTTTGAATCTCTGATGGGCCTTAACCTACACCGAAAGAACACCACCCAAGTCTGCGGACAGGTAGACTATATTCAGAAAATCTCTACAACACCAGAGCTCGTGGCAGCCAAGGCCTCATCACCAGCTGATGCGCTATACGATGTGAAGATCAAAGACGAACCGCTGGACGCAGATGAGATggggccacagccacagaaggAAGCTGGTCTTCATGTGTACATCAAAGACGAGCCCCTGGACGAGGAGATGCCCGACGTGTGTGACAGCATCAATACAGACCCCAAAATGGCAAATCCCACAAAGAAGATGCCAGTGTCTTCGAAAGGATCGATCTGGGCAAGCCTACCCGTTGAGCTGAGGAACAAGCTGCGATTGCCTGCCTTGAAGCCCAAGCAAGAGATACAAACTACCCCTCGGCCACCCTTCAAATTTTCAAAATGGAATGGCCAACCAGCATCAAATGCCACTTCTGGTGGAGTCCAGCGGAGTTTATTCAAAGTTTTGCCTAACGGCCAAAAAGTAAACGTTACGGATATGTTGAAGAAAGTCTCAAATTCTAAGACGACTATGCATGGAAAGCCCCCAATATCCCCTAATATACTGAAAGTATTGCCCAACAACTGCATGGTCATTAAATTGCCGCCAAATACAAAAATTGTAAAGCTGTCGAATCAGCCGAGTGCAGTTGCCACTGCAACGTCCCCACAGAACGTTGTTCAGTTGCCAGACTCGCTTACAATTAGCAAGATTACGCCAGAAGGAGCGACATCCCCCGTTACGACTAGTCCAGTGGATTATAGACCCCTGCTGCCTCCCCGGGATCGCTGTTACTCCCTGAAGAATCGACCAGAATGTCAGGAACTGATTACagaatttcaaaatcaaatacGCTCCATTGAAAAAACGCTTCCAATTCCGGGAACAGTTTTACATTCACGGGATAAAGAAACAAAGGGACTAAACGCTGAACCAGTAGCCCCAGTGGAAGGCGAGCCATCGAATGTGGAAGTATATATCAATCCCGGGGCCCACACGGTGATGGCAGAACTGCGGAAGAAATACCCGAACAACCTTTTCTTCTGGACTTGTCCCATCTGTACGCGCTGCTATGAGGAAGGCTACGCATTTCGCAGGCATCTGATTCAGGAGCATGAACTGAAGCGCGACAACTTGTCAGAGCTAAAAGTAGTTTTGAAGCCCCTAAGAAAAACGATTAATCCAGATCAGCAGGAGGCATCGGAAACTAATCTAGAACCGGAATCAAGTGTGACAGAGCCTGCTGCTTCAGTGTGTGATTCAGTTTCGGAGATATCAAAGCCAGCAACTCTGACAAAAGAAATACCACCTTTGCTTACATCCGCACCGACTCTAGCAATCGAAGCAGGACCATCAGAGTCCGAACCAAAGATATATAAACTCAAGCCCCCACATGTAGATGACACAAAGCTATCGCAGTTCCAGTGCCCCACGTGCCTTAAAATATTCACCACCCAGGGAGGCATGCGAATTCATATGTCCATCCACACGGGGGAAATGCCATACAAGTGCCAATATTGCGACAAGCGCTTTCGGACTCCAGGTCAAGTGCGGGTGCACTTGCGCCGACACACTGGGGAGAAACCCTTCCAATGCAAGATCTGCGGCCTGGATTTTACTCATCGAGAGACTCTCATCTCTCACCTATCGCGCCATATTGGAATGAAACGCTACAAGTGCTACGGCTGTGACAAGTACTTTGTTGTAGTTAGCGGCCTTCGGGCCCATCGTCGCCTGCGGCCGGATACGTGTGGCAAGGTTAAATTCACGGCCCGAGCCCATGGGCCTCGGGTGCGTGTCATAAAAGGGCAAGTCGTCTTTGAGCACCATCCCAGCTATAACGGCTACTTGCGCAGTGAAGATCCGCTCGATATATTGAAAGAGCGCGGCCAAATCGACTCAATCCCTTCGAACCAAGTCGAGAACAAGCCTGAGgccgaagccgaagctgaGGGTCTAGATTag
Protein Sequence: MHVDLTIIKEEIDIDDTTIKLEVEDNVPDEAMDVSCASGAVKILEEHANMITVPLSDHKSEDELKFIASLGTLDAQQLFAEPSQNQNGCPYECHICHLQLPTELEIKAHFVNHQMNRHFCRHGCGAWCGTLELVLEHEYRQHSQGIYTFCCRICDLRVDGADRLASHMKSHCYVNRYVCAICRRPFESLMGLNLHRKNTTQVCGQVDYIQKISTTPELVAAKASSPADALYDVKIKDEPLDADEMGPQPQKEAGLHVYIKDEPLDEEMPDVCDSINTDPKMANPTKKMPVSSKGSIWASLPVELRNKLRLPALKPKQEIQTTPRPPFKFSKWNGQPASNATSGGVQRSLFKVLPNGQKVNVTDMLKKVSNSKTTMHGKPPISPNILKVLPNNCMVIKLPPNTKIVKLSNQPSAVATATSPQNVVQLPDSLTISKITPEGATSPVTTSPVDYRPLLPPRDRCYSLKNRPECQELITEFQNQIRSIEKTLPIPGTVLHSRDKETKGLNAEPVAPVEGEPSNVEVYINPGAHTVMAELRKKYPNNLFFWTCPICTRCYEEGYAFRRHLIQEHELKRDNLSELKVVLKPLRKTINPDQQEASETNLEPESSVTEPAASVCDSVSEISKPATLTKEIPPLLTSAPTLAIEAGPSESEPKIYKLKPPHVDDTKLSQFQCPTCLKIFTTQGGMRIHMSIHTGEMPYKCQYCDKRFRTPGQVRVHLRRHTGEKPFQCKICGLDFTHRETLISHLSRHIGMKRYKCYGCDKYFVVVSGLRAHRRLRPDTCGKVKFTARAHGPRVRVIKGQVVFEHHPSYNGYLRSEDPLDILKERGQIDSIPSNQVENKPEAEAEAEGLD

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00481075;
90% Identity: -
80% Identity: -