Basic Information

Insect: Drosophila lowei
Gene Symbol: -
Assembly: GCA_008121275.1
Location: CM017779.1:22766443-22768979[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 7 0.003 0.22 11.9 0.8 1 23 193 215 193 215 0.98

2 7 0.0049 0.36 11.2 4.5 1 23 558 580 558 580 0.96

3 7 6.2e-05 0.0046 17.2 3.1 1 23 586 608 586 608 0.98

4 7 2.8e-05 0.0021 18.3 0.6 1 23 614 637 614 637 0.96

5 7 2.1e-06 0.00016 21.8 2.9 1 23 643 665 643 665 0.97

6 7 5.6e-06 0.00042 20.5 0.7 1 23 671 693 671 693 0.97

7 7 1.1e-05 0.00086 19.5 2.3 1 23 699 721 699 721 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	7	0.003	0.22	11.9	0.8	1	23	193	215	193	215	0.98
2	7	0.0049	0.36	11.2	4.5	1	23	558	580	558	580	0.96
3	7	6.2e-05	0.0046	17.2	3.1	1	23	586	608	586	608	0.98
4	7	2.8e-05	0.0021	18.3	0.6	1	23	614	637	614	637	0.96
5	7	2.1e-06	0.00016	21.8	2.9	1	23	643	665	643	665	0.97
6	7	5.6e-06	0.00042	20.5	0.7	1	23	671	693	671	693	0.97
7	7	1.1e-05	0.00086	19.5	2.3	1	23	699	721	699	721	0.97

Sequence Information

Coding Sequence: ATGGAGCGCAAAGAAGTGGACGCACAGCAGTTCATTGATCACACGCTGCTGGCCTCGGAGCTAATGCGGGATCCAAACCACTTTATTATGGATCTGATCGATCACACAGGAGTGTTCCCCAAGGCCGAGGGACCCACCAATCTGACCACCAACACGGGAACTCCCCCCAATGATGGGACTGGGGGCTACGTAGAGAAGGAGCTGAACTTCCACAACACAATCTTCCAGCTGGTGAACAAGCATGTGAACGAGTCCTCATCCGCGGACAGCGGTGTGGGGCCGGTGGTGTCGCAGCAAGTGCAGCAGCCGGCATTCCCAGCCCTGGCCATAGAACCGACCGTACCCATCGATGTCTCGGCGTGTCTGCACGCTGTGGACGATGACGATCTTCTGTATGTCCACAATGCTCTAACGACCAATGCCCGCAAGGTGCTGCCCCACAAGAAGCGCATCTCGAGGAAGCTGAAGGGCAACATCGATGCCGagatggagcagcagcaccagcagcaccagcaccagcagcaccagcagcacaaGCATGTCATTCAGCATGTTCCACCAGGAGCGGCTTCGCTCTATAGCTGTGAGATCTGCGGCTATGCAGTGCACACACAGTTGGACTTTTTTGCCCATCTTAAGCAGCATTATGAGCCACCAATGGCCATGGAACAGCGATTGGAAGTTCCGatccaacaacagcagcagcagcagcagcaagaacagCAGAAGGAGCCATTGGACATGTGCGGTCTCTCCACACAGGATAAGCTTCAACAGGAACAGGCCAAACTGGATCAGGTCTTTCACGATGTTCAGCTGAACTTTGAGAACTTTCACCCCATCAGCCATGTGGATCACGATGTgggagtgggcgtgggcgtgggtgtgggAGTGCCTGTAAATGTAAATGATGTTGGCGTCAATATGGTCATGCATGGCGAAGCCACAGACAAGCTAAATACCGTGGGAGCCACCAGCACCGCGCCCAACGTCAACGTCGTGGTCCCCGTTGTTGATGATGTGGAGTTCAGTGACACGGAGGACATGCTAGAGGGCATACGGAACGTAGTGGATAAGGTGTCCATCGAGGACACTTGCGATGAGCTGGTGGAACTGGAGCTAACCACAGCCACGATACGAGCGCCCTGGTTTAACAACAACTTCAGTGACATCACATTCccggggctgctgctgccgggaGAGCCGCCTCCAGCGACCGCCGAGCAAGCGACGACGCCGCTGCTCAAAGAGAATCCCAACGGAACGGAGCAGATGGATTTGGATTTCCTCAATGCCAGCAAACGAGAGGaatcaaatgaaatcaaaatgGAGAAGGCGCTGGAAAAACCCATTGAAGGGATTGAACAACCCTTACTGGTGGCGCCACCAATGTGCTGTACCTCTCCGGCACCGCCTGCTGCGCCACCGCCCGGCTCGACCATTGAACAGCTGCGTCGATCGCCGCTAGTCCTCAACGAAGCCGGCTTCAAGCTGGAGGCCGTTGAAATGCCCGACCACAGCGCACCACCTTCACCATTCGACAATGGTGACGCAGACggagacggcgacggcgatggcgacggcgAGGATGAAGACAATACCGATAGCTATGCCatggaaagtgcagccacgaGTCCCAGCGAGGACTCGCCGAGCAAATCGAGGAGGAAGCACTTCTGCGACAAATGCAACAGGGATTTCAATTCGTACAATGCCCTCAAATACCATCAATATACACATAACCAGGAGCGCTCGCACAAGTGCAGAAGCTGCGAAAGATCCTTCTACAACCAGAGTGCGCTCACGGCCCACGAGAAAACGCACACTGGGATAAAGCCCTTCGAGTGCGAGAAATGCGACTCCAAGTTCCGACAATGGGGTGATCTCAAGTACCACATCATTTCCAGACACAGCGACATCAAGGCCCACATGTGCGAGTTCTGCGGCAAGAGCTTTTCCCGAAGGTACTCTCTGGTCCTGCATCGACGGATCCACACCAGCGAACGGAACTACGCCTGCCAGTACTGCGACAAAACGTTTCGGGCCAGCTCTTACCTTCTGAGCCACGTCAAGGTGCACACGGGAGAGCGACCTCACGAGTGCACCGTATGCCAGAAGAGGTTTCGCGTCTCGGGGGATCTCAAGCGGCACTCGCGTATCCACGATCCGGCCAGAAAGAGCCAGCCTCCAGCCGCCAAGGTGGAGAAAAAAAAGCTGAAGCAAATCAAAGATGAGCAAGAGAATGAGGAGGAGGTGGTGGCGGTGTCTGccacccaaaaacaaaagtctGACGCCCTGTGCGACGAATCTGAGCAGGAAATTCTCGGCTTATAG
Protein Sequence: MERKEVDAQQFIDHTLLASELMRDPNHFIMDLIDHTGVFPKAEGPTNLTTNTGTPPNDGTGGYVEKELNFHNTIFQLVNKHVNESSSADSGVGPVVSQQVQQPAFPALAIEPTVPIDVSACLHAVDDDDLLYVHNALTTNARKVLPHKKRISRKLKGNIDAEMEQQHQQHQHQQHQQHKHVIQHVPPGAASLYSCEICGYAVHTQLDFFAHLKQHYEPPMAMEQRLEVPIQQQQQQQQQEQQKEPLDMCGLSTQDKLQQEQAKLDQVFHDVQLNFENFHPISHVDHDVGVGVGVGVGVPVNVNDVGVNMVMHGEATDKLNTVGATSTAPNVNVVVPVVDDVEFSDTEDMLEGIRNVVDKVSIEDTCDELVELELTTATIRAPWFNNNFSDITFPGLLLPGEPPPATAEQATTPLLKENPNGTEQMDLDFLNASKREESNEIKMEKALEKPIEGIEQPLLVAPPMCCTSPAPPAAPPPGSTIEQLRRSPLVLNEAGFKLEAVEMPDHSAPPSPFDNGDADGDGDGDGDGEDEDNTDSYAMESAATSPSEDSPSKSRRKHFCDKCNRDFNSYNALKYHQYTHNQERSHKCRSCERSFYNQSALTAHEKTHTGIKPFECEKCDSKFRQWGDLKYHIISRHSDIKAHMCEFCGKSFSRRYSLVLHRRIHTSERNYACQYCDKTFRASSYLLSHVKVHTGERPHECTVCQKRFRVSGDLKRHSRIHDPARKSQPPAAKVEKKKLKQIKDEQENEEEVVAVSATQKQKSDALCDESEQEILGL

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00517930;
90% Identity: iTF_00474008;
80% Identity: -