Dlow010188.1
Basic Information
- Insect
- Drosophila lowei
- Gene Symbol
- -
- Assembly
- GCA_008121275.1
- Location
- CM017781.1:2497456-2499960[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 12 0.011 0.79 10.2 3.7 3 23 272 292 270 292 0.97 2 12 0.0029 0.22 11.9 0.6 1 23 298 323 298 323 0.92 3 12 0.022 1.6 9.2 1.9 1 23 330 355 330 355 0.95 4 12 5.8e-05 0.0044 17.3 1.3 1 23 367 389 367 389 0.98 5 12 1.6e-06 0.00012 22.2 0.1 1 23 396 418 396 418 0.98 6 12 0.01 0.78 10.2 0.2 1 23 424 446 424 446 0.97 7 12 0.017 1.3 9.5 3.0 1 23 452 475 452 475 0.98 8 12 0.0088 0.66 10.4 4.4 1 23 481 503 481 503 0.96 9 12 0.088 6.5 7.3 5.3 2 23 510 531 509 531 0.96 10 12 9.8e-05 0.0073 16.6 0.2 1 23 639 662 639 662 0.95 11 12 0.084 6.3 7.3 1.3 1 21 668 687 668 690 0.75 12 12 7.2e-07 5.4e-05 23.3 3.9 1 23 696 718 696 718 0.98
Sequence Information
- Coding Sequence
- ATGGATATGGCCAGGACATATTCGATACACACCTTGTGTCGCATTTGCCTGAACCACTTGCAAAACGATGCCGCATACGATTTGTATCTGGTGCCAGGCCTGTCGAAAAAACTGTGTCTGTGTACGTCCCTCTCCGTCGAGCAGAACGATGGCTTTCCCAAGAATCTGTGCAGCAATTGCTACACCAGGCTGAACGACCTGCACGAGTTCCAGAAACTATGCGTCGACTCGGTCCAGAAGTTCCAGGACCTTGTCGCCAGCAACGTTTTCACCTGCCAGACGAACTTCGATGTCTTGGATCCCAGTTCGACGGCCCACGATCTGCCTGGAGAGGATGAGGATCACATCAACTTTGATCCCCTGTTAAACCACAAAATGGAGCTGATTGAGAACGAGGAGGATGTGTTCAAGATGCTGGAGCATGTGGACAAGGAGGCCGAAGAGTGTGAGAACGAGAGCGTCAAGCAGGATAAGGTGAAGGCTTCGCCCAGCAACGTACTGAAAATGTTCGACGACGACTCTTCTATTGAGAGCGGCAATGACAACGACAGAGATCTGGACTTTGAGCCCAACAGCAGCGACGACGACATTCCTTTGGCCCAACGCATGAGGGGATccacccagtcccagtccacCCGTACACCAGCCAAGTcgaagcccaagcccaagaagaagaaggtggAGGACTACGACGACTTCAGCAGCTCCACCTCCGACtcggacgacgacgatgacaaCGATGGCTCGAACAGGGAGAAGCCCAAACGCAAGAGGATTCCAGCCGATGAGCGACACCTTCATCGCATCATCGACTGCCACATTTGTCATCAGAAGTTCAAGAAGGCCATCCGCTACGAGGAGCACATGAAGTACCACAACGATCTGCTCCCCTTCCAGTGCAAAGTGGAGACCTGCCGGAAAGGATTCACCACAGCGAATGGCCTGCGCATCCATGTGGACCATGCCCACACCGAACTGTCCGAGGTGCACCACTGTCCCGCGGAGGGATGCGAGAAGACGTTCCCCCGTATCAGGCTGCTCACGTTCCACATGAAGAAGGTGCACAACATAACCAAGGCAGCCGCACCGCTGCGCGACTTCCCCTGCCCGGAGTGCGATACCGTCTTCCGCTGCCCCACGGCCCTCAAGAAGCACATGTACAAGCACACGGGCGAGGAGTTGCCCTACCCTTGCAACATCTGCGGCAAGCGGTTCGTGATCAACAGCGCCCTCAGGGATCACTTGATGCGACATGCGGGCATCAAGAACCACGTCTGTCCCTACTGTGGCGTGGGCAAGACCACGCGCCAGGAGTGGAACGCCCACATTCTCACCCACACCAAGGAGAAGAAGTTCAAGTGCCGGCAGTGCGACCACGCCTCGCACAACAAGCAGGCCCTGTCGAACCACATCAAGGTGGTGCACGAGAAGCGGAAGGATTTCGCCTGCCAGTACTGTGGCAAGACGTTTGGCAAGTCGCATGCCTGCAAGGTGCATGAGCGGAGCCACACCGGAGAAAAGTGCTGCGAGTGCAAGATCTGCGGCAAGATCTTCCTCTGCGAGAAGAGCCTCACGAAGCATCTGAAGACGCACGAGAAGCGGGATCTGCCACCTTCAGAGccgcaacggcaacaacagctTAACATTCCCATTCCAATACCAGGCCAAATGCAAGGCGATGGCCTGGGGAAtcccaataccaataccaatatcAATCCCAATCCAAACGACGACATGCTCAAGGCTTGCGCTAGCAGTGGCGGGCCCGCTGCACCGTTGGCCAAACAGAAGAACTCCAGACGCGTCCAACGGGTGGACATTTCACAGCTGGCGGGCACCGCCGTCAATCCCATACCTTCTGTATCGGTGCCCTCGTGGTCGCCGCAGGTGAACTTCACCAAGAAGGAGGGCCAGCATATCTGCCCCGGCTGTGGACGAGGCTTCAACAACATTGGCAACATGAAGCTCCACTACAAGATCATCCACGAGAAGGTGAAGGACTTTGCCTGTCGGTTCTGCCCCAAGCGCTTCTCCAAGGCCCAGATCCTGCGGCACCACGAGTGGATCCACACGGGAGAGAAGCCCTTCGAGTGCAAGATCTGCAACAAGCATTTCCGCCAGGAGACGGCCCTCAAGAAGCACATCAAGACGCACGAGAAGCCCGGCCGCCGACATGTGCCGGAGAGGAGTGCTCCGACTGTACCCACCTTCATGAAACTGGATCCTGAGGCCGAGCCGAGGAACTACGATCTGTATCAGGATCCAGCTGCCGAGAGGGCGGCGGCCACCGCTGAGCTGCTCGCCCACCAGATGGAGGAGAACGAGGCCAAGCGAAAGGCGGACATCGAGCGCCAGAAGATCGCTGCGGCTGCCTGCGAGCAGCTAACAAAGctgcagaagcagcaggagatTATGAAGGCCACCACATCCTACGACGGCTACTATCAGCAGAAGGCCGAGGCCGATGGCACCAGTCTGGATTCCCTAAAGATCGATCATGTGTAG
- Protein Sequence
- MDMARTYSIHTLCRICLNHLQNDAAYDLYLVPGLSKKLCLCTSLSVEQNDGFPKNLCSNCYTRLNDLHEFQKLCVDSVQKFQDLVASNVFTCQTNFDVLDPSSTAHDLPGEDEDHINFDPLLNHKMELIENEEDVFKMLEHVDKEAEECENESVKQDKVKASPSNVLKMFDDDSSIESGNDNDRDLDFEPNSSDDDIPLAQRMRGSTQSQSTRTPAKSKPKPKKKKVEDYDDFSSSTSDSDDDDDNDGSNREKPKRKRIPADERHLHRIIDCHICHQKFKKAIRYEEHMKYHNDLLPFQCKVETCRKGFTTANGLRIHVDHAHTELSEVHHCPAEGCEKTFPRIRLLTFHMKKVHNITKAAAPLRDFPCPECDTVFRCPTALKKHMYKHTGEELPYPCNICGKRFVINSALRDHLMRHAGIKNHVCPYCGVGKTTRQEWNAHILTHTKEKKFKCRQCDHASHNKQALSNHIKVVHEKRKDFACQYCGKTFGKSHACKVHERSHTGEKCCECKICGKIFLCEKSLTKHLKTHEKRDLPPSEPQRQQQLNIPIPIPGQMQGDGLGNPNTNTNINPNPNDDMLKACASSGGPAAPLAKQKNSRRVQRVDISQLAGTAVNPIPSVSVPSWSPQVNFTKKEGQHICPGCGRGFNNIGNMKLHYKIIHEKVKDFACRFCPKRFSKAQILRHHEWIHTGEKPFECKICNKHFRQETALKKHIKTHEKPGRRHVPERSAPTVPTFMKLDPEAEPRNYDLYQDPAAERAAATAELLAHQMEENEAKRKADIERQKIAAAACEQLTKLQKQQEIMKATTSYDGYYQQKAEADGTSLDSLKIDHV
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00484614;
- 90% Identity
- iTF_00484614;
- 80% Identity
- iTF_00575043; iTF_00580969;