Basic Information

Insect: Drosophila lowei
Gene Symbol: gfi1b
Assembly: GCA_008121275.1
Location: CM017777.1:43661485-43663335[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 8 0.0011 0.083 13.2 2.9 1 23 261 284 261 284 0.95

2 8 0.00014 0.01 16.1 0.1 2 23 295 316 294 316 0.97

3 8 1.9e-05 0.0014 18.8 1.1 2 23 326 348 326 348 0.92

4 8 1.9e-05 0.0014 18.8 0.1 1 23 354 376 354 376 0.97

5 8 1.2e-05 0.00087 19.5 0.5 1 23 382 404 382 404 0.97

6 8 0.00047 0.035 14.4 1.3 1 23 409 431 409 431 0.96

7 8 0.00012 0.0089 16.3 2.1 1 23 437 459 437 459 0.97

8 8 0.0022 0.17 12.3 5.0 1 23 465 488 465 488 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	8	0.0011	0.083	13.2	2.9	1	23	261	284	261	284	0.95
2	8	0.00014	0.01	16.1	0.1	2	23	295	316	294	316	0.97
3	8	1.9e-05	0.0014	18.8	1.1	2	23	326	348	326	348	0.92
4	8	1.9e-05	0.0014	18.8	0.1	1	23	354	376	354	376	0.97
5	8	1.2e-05	0.00087	19.5	0.5	1	23	382	404	382	404	0.97
6	8	0.00047	0.035	14.4	1.3	1	23	409	431	409	431	0.96
7	8	0.00012	0.0089	16.3	2.1	1	23	437	459	437	459	0.97
8	8	0.0022	0.17	12.3	5.0	1	23	465	488	465	488	0.98

Sequence Information

Coding Sequence: ATGACCAACCATGGAGCTGGAGGGGCAGTGGCCAATGCAAGTGCATCTGCCTGGCACAAATGGTGTCGCCTGTGCGCTAAGGACCACCCGCAGAACGCGAACGTCTATGCGCGTCATCAGCAGGACCAGCAGTCCTCCTGGACGAGCATGTTGGCTATGGCCATTGGCAAATACTTCTGGGTGGATATCAAAGTGGAGGACGAACTGAGCAACCACTTGTGTGTGGAATGCTTTACGCTAATGGAGTGCCTGATTGAGTTCTCGGAGCGGGTGCGACGCGTCCAGACGCTCTTCAATAGATTGCAGAGCCTATCGCCGGATGGGTATGTGGACTTTGAAGAGCTGCGAACAGATTGCGGTCTACTGACCGACGAGTGGAAGCACGTCATGTCGAGAGCAGTCGCGCCGCCGCGGCGCTTGCCGGAGAAAGTAATTGAACAGGAAGTAGAAGAGCATTTCCGAGTGCAGGAGATAATGGATGAGGAAGAACGAGAAATGTCCGAGGAGCAGGAAGTGGAAGCGCAAGAAGAGTATGTTGAGGCAGAGGAACTTCCAGACTGTATGGAGGATGAAATAGTAGAGGAGTGCATCGACGAGGATTCCGACATGATAGATCAGAGCGAAGGCGAGGAATATAATGTGGATGCGTACAAAGAGCCATCAGAGGAGCCGCCCGATGATGCGGAAATAGTAAAAATAGAGCAGGAAATATGCACAGAATCGGATGTAGAGGATGACCCTAGGCCAGACCACTTGGATGAGAAAGCTACCATACACTCATACAAATGCGATATCTGCTGCAAAACCTACAAAAAGCCGAATGCTTACAAGAGACACATGCTGGACGTGCATAATGTCATGCCCGACGACTTGCCCAATCTCGAGTGCAAGCAATGCGGGGCCATCTTTCCGACCGTGCCTCAGCTGCAGACCCACGAGCGCACCCACTTGCCGGCCAAGGAGAAGGCGGACAATTCCTGCCCCCACTGTTCGAAGCTCTTTACCACGTCAGGAACACTCAAGCGCCACATCGAGGGCATCCATAATGACATCAAGCCCTACATTTGCGATATCTGTGGCAGAAGCTTCAATTTACTCAGCGCTCTCAATGACCACAAGCTGGTCCACACCGACGAGTGTCCCTTTGAATGCCCCGTCTGTCAGCGACGCTTCAAGAACAAGGCCAGACTCAGGGTGCATGCCGACACGCACAGTGCCACTGTCTACGAGTGCAACATCTGCGGCCTGAAGCTCAAGACGCGGCGAACCTTCAACAAGCACAAAGTAGTCCACTCCGACAAGAGGCAGCACAAATGTGAGCAGTGCGGAGCGGAATTCAAGCGAACCAAAACATTGAAGTCCCATCTCATCCTGCACACGGGCATACGGCCGTACAAGTGCAATTTCTGCGACAAGGACTTCTCCAATGGCTCCAATTGTCGTTCGCATAAGCGTAAGGCGCATCCCAAGGAGCTGGAAGAGGAGGAGTCCAAAGGAGTGTCACGTTCCACAATTTTGCCCGTACTCGAAGAGCTGGCAAAGGCCTCGAATCGCATCAAGAGCCCTGCCAAACGCTTTAAAAGGAAGCCGAAAAGTAATGGAAAAGCAAAAGAATCTCCAGCAAAGGACACGGAAGGTGAGAGCGAGATCCTCTACGAACTGGTAGGGGATCTGTAA
Protein Sequence: MTNHGAGGAVANASASAWHKWCRLCAKDHPQNANVYARHQQDQQSSWTSMLAMAIGKYFWVDIKVEDELSNHLCVECFTLMECLIEFSERVRRVQTLFNRLQSLSPDGYVDFEELRTDCGLLTDEWKHVMSRAVAPPRRLPEKVIEQEVEEHFRVQEIMDEEEREMSEEQEVEAQEEYVEAEELPDCMEDEIVEECIDEDSDMIDQSEGEEYNVDAYKEPSEEPPDDAEIVKIEQEICTESDVEDDPRPDHLDEKATIHSYKCDICCKTYKKPNAYKRHMLDVHNVMPDDLPNLECKQCGAIFPTVPQLQTHERTHLPAKEKADNSCPHCSKLFTTSGTLKRHIEGIHNDIKPYICDICGRSFNLLSALNDHKLVHTDECPFECPVCQRRFKNKARLRVHADTHSATVYECNICGLKLKTRRTFNKHKVVHSDKRQHKCEQCGAEFKRTKTLKSHLILHTGIRPYKCNFCDKDFSNGSNCRSHKRKAHPKELEEEESKGVSRSTILPVLEELAKASNRIKSPAKRFKRKPKSNGKAKESPAKDTEGESEILYELVGDL

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00517903;
90% Identity: iTF_00575035; iTF_00580964;
80% Identity: -