Basic Information

Insect: Drosophila lowei
Gene Symbol: -
Assembly: GCA_008121275.1
Location: CM017777.1:10618335-10621505[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 13 9.9 7.4e+02 0.8 2.1 3 16 58 71 57 73 0.84

2 13 0.00076 0.057 13.8 0.6 1 23 214 237 214 237 0.97

3 13 3.1e-06 0.00023 21.3 4.6 1 23 242 265 242 265 0.97

4 13 2.5e-05 0.0019 18.4 3.2 1 23 270 292 270 292 0.98

5 13 3.1 2.3e+02 2.4 2.9 2 23 299 322 298 322 0.90

6 13 0.00056 0.042 14.2 3.9 3 23 333 354 332 354 0.95

7 13 0.0033 0.25 11.8 0.2 1 23 360 383 360 383 0.96

8 13 0.0075 0.56 10.6 0.3 2 23 394 416 393 416 0.95

9 13 0.0043 0.32 11.4 0.2 1 23 445 467 445 467 0.96

10 13 7.5e-06 0.00056 20.1 4.0 1 23 474 496 474 496 0.97

11 13 0.00021 0.015 15.6 0.1 2 23 503 524 503 524 0.97

12 13 0.00043 0.032 14.5 0.8 1 23 531 553 531 553 0.99

13 13 0.00012 0.009 16.3 3.7 1 23 559 582 559 582 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	13	9.9	7.4e+02	0.8	2.1	3	16	58	71	57	73	0.84
2	13	0.00076	0.057	13.8	0.6	1	23	214	237	214	237	0.97
3	13	3.1e-06	0.00023	21.3	4.6	1	23	242	265	242	265	0.97
4	13	2.5e-05	0.0019	18.4	3.2	1	23	270	292	270	292	0.98
5	13	3.1	2.3e+02	2.4	2.9	2	23	299	322	298	322	0.90
6	13	0.00056	0.042	14.2	3.9	3	23	333	354	332	354	0.95
7	13	0.0033	0.25	11.8	0.2	1	23	360	383	360	383	0.96
8	13	0.0075	0.56	10.6	0.3	2	23	394	416	393	416	0.95
9	13	0.0043	0.32	11.4	0.2	1	23	445	467	445	467	0.96
10	13	7.5e-06	0.00056	20.1	4.0	1	23	474	496	474	496	0.97
11	13	0.00021	0.015	15.6	0.1	2	23	503	524	503	524	0.97
12	13	0.00043	0.032	14.5	0.8	1	23	531	553	531	553	0.99
13	13	0.00012	0.009	16.3	3.7	1	23	559	582	559	582	0.98

Sequence Information

Coding Sequence: ATGGAAACTTGTCGTACCTGTGCGATTTCCATGTTTGTTTGCCATGGCAGCAACAATTTTCTGGACCTATTCCATCCCACGTGCTGGCAGAGTGAAATGGCCCAGATACGACTGGAGTTTGTCCACTGGAATCTGAAGATTTCTCCCAACGATGGATTGCCACAGAAAATATGCAGCGACTGTTTTACCAAGTTCTGCTCCATTTACACATTTCGACTGGGCTGCCAGGAAGCGCAGTTGAAGTTGTCGAACATTTATGACAAAATCGATGCCAGCAGCTTGGAGGATGAATGCCAGGAAGAGGAAGGGGAAGATGAAGAATCGGAAGCTGTGCCAGAAACAACAATTAtaggaacaacaacaacatcaacaacaacgacgGTTTCAACCGAAACACAACCaaacactgccactgccccccCAATAGAGTTTTTTGTGGAAACCATAGGCCACACCGAAGCGAATAGCGATAACGAATCACAGCCACTTTAcaaggatgatgatgatgatgacattGATGCCACTCAGGAACTGACCATTAGCTATGCCTGTAAGTTCTGCTTTAGGCCGCAGGAGAGCtaccagctgcagcagctgctcctggAACACATAAATGCCAGCCACGATCCAGATCAGCCGTACAACTGTCCGGAGTGTGAGGAGTGCTTCCAGGATGCTGCCTCCCGGACTGTGCACCTCAAGAGCAGTCATgtggaaaaacagtttaagTGCGAGGTGTGCGGAAAGCAGTATAGCGATCGCCACAACCTGCGCCATCACATCGAGAAGTATCACTCGGAGACGGACTTTGAGTGCACCATGTGCGAGAAGCGCTTCTTTACGCGCAAGAGCCTCAACTATCACATGAAGTGGCACAATCCGGAGCGTCAGCTCAAATGCCGGCAGAGCGGCTGCGAGCGTCTGTTCATCAATCAGCGGCATCTCGAATGCCACGAAGCCACCCATACGGGCGCCAGTGCCAGGAAGAGCGAGCACTGTGGCTTCTGTGGTAAAACTTTCATACACCTAAAGACACTACGATGGCATATCTATAGACAGCATGGCGGGGAAAAGCCCTACAAATGCGCCAACTGCACGGAGGTGTTCGCCTCGTATGCAGAGAAAAGGATTCATATGCTGGAGCGGCACAGGGAGAACCTAACGCCCATTGAACGCAGCGAATGCATGTTGTGCCGCCAGCCCTTTGGCACCGAGCAGGATCTCATACATCACATGTCCGTGGATCATTTGCAGCGTGCGGCCAGCGCGCCAGTGATTGCCAACAATAAGCGTGTCCTGCAGCAGAAGCGAGAGCGTCAGTATTCGGGACTCTTTCAATGTGACAGCTGCGCCCAGAGATTCAATATGAAGTCGGCCCTGGATCGCCATGCCGCTGTCCATTCGGAGAAGGACAGGCCGCATGCCTGCCCGCACTGCTCCAAGCGTTTCAAACGGGCCCAGGACATGAAGTGGCACATCAAGACGCACGAGAAGGAGAAGCCCAATGTTTGTGACGTGTGTGGCAAGGCCTTTGCCTTGAAATATGTCCTCACACAGCATCGGCTCAGCCATGAAGTTTTGGAGAAGAACTTTAAATGCAACGTTTGCGGTCGGGCCTATCTATTTGAAAAGAGCCTGCGGCTGCATCAACGAGTCCACACGGGCAACACCTACTACAAATGCGATCTGTGCCAGGAACGCTTCGTGACGCACATTAAATTGAAAACTCATATGCAGAAAACGCATGCACATGCATCTGAGACGCCTTCACCGGACTCCCTGGATGATTTGATAAAGATTGTGATTTCCTAA
Protein Sequence: METCRTCAISMFVCHGSNNFLDLFHPTCWQSEMAQIRLEFVHWNLKISPNDGLPQKICSDCFTKFCSIYTFRLGCQEAQLKLSNIYDKIDASSLEDECQEEEGEDEESEAVPETTIIGTTTTSTTTTVSTETQPNTATAPPIEFFVETIGHTEANSDNESQPLYKDDDDDDIDATQELTISYACKFCFRPQESYQLQQLLLEHINASHDPDQPYNCPECEECFQDAASRTVHLKSSHVEKQFKCEVCGKQYSDRHNLRHHIEKYHSETDFECTMCEKRFFTRKSLNYHMKWHNPERQLKCRQSGCERLFINQRHLECHEATHTGASARKSEHCGFCGKTFIHLKTLRWHIYRQHGGEKPYKCANCTEVFASYAEKRIHMLERHRENLTPIERSECMLCRQPFGTEQDLIHHMSVDHLQRAASAPVIANNKRVLQQKRERQYSGLFQCDSCAQRFNMKSALDRHAAVHSEKDRPHACPHCSKRFKRAQDMKWHIKTHEKEKPNVCDVCGKAFALKYVLTQHRLSHEVLEKNFKCNVCGRAYLFEKSLRLHQRVHTGNTYYKCDLCQERFVTHIKLKTHMQKTHAHASETPSPDSLDDLIKIVIS

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00473982;
90% Identity: iTF_00575023;
80% Identity: -