Basic Information

Insect: Drosophila lowei
Gene Symbol: -
Assembly: GCA_008121275.1
Location: CM017778.1:12961863-12965553[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 17 0.037 2.8 8.5 0.2 2 23 353 375 352 375 0.96

2 17 2.8 2.1e+02 2.5 0.0 1 23 382 407 382 407 0.93

3 17 0.03 2.3 8.7 2.2 2 23 418 439 418 439 0.93

4 17 0.0033 0.25 11.8 0.2 3 23 491 511 489 511 0.95

5 17 0.00052 0.039 14.3 0.5 1 23 519 542 519 542 0.98

6 17 0.00073 0.055 13.8 0.4 2 23 547 568 546 568 0.97

7 17 6 4.5e+02 1.5 0.1 1 20 576 595 576 597 0.84

8 17 3.3e-05 0.0024 18.1 1.1 1 23 616 640 616 640 0.91

9 17 0.12 9.2 6.8 0.5 3 21 647 665 647 666 0.90

10 17 0.07 5.3 7.6 0.5 1 23 685 710 685 710 0.95

11 17 0.67 50 4.5 1.9 2 23 728 750 727 750 0.94

12 17 0.0039 0.29 11.5 0.1 2 23 756 778 755 778 0.92

13 17 0.009 0.67 10.4 0.1 2 23 782 804 781 804 0.95

14 17 4.8e-05 0.0036 17.5 2.0 1 23 810 832 810 832 0.98

15 17 0.0098 0.73 10.3 1.4 1 23 836 859 836 859 0.93

16 17 3.8e-05 0.0028 17.9 1.8 1 23 865 888 865 888 0.96

17 17 4.6e-06 0.00034 20.8 0.7 5 23 901 920 892 920 0.85

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	17	0.037	2.8	8.5	0.2	2	23	353	375	352	375	0.96
2	17	2.8	2.1e+02	2.5	0.0	1	23	382	407	382	407	0.93
3	17	0.03	2.3	8.7	2.2	2	23	418	439	418	439	0.93
4	17	0.0033	0.25	11.8	0.2	3	23	491	511	489	511	0.95
5	17	0.00052	0.039	14.3	0.5	1	23	519	542	519	542	0.98
6	17	0.00073	0.055	13.8	0.4	2	23	547	568	546	568	0.97
7	17	6	4.5e+02	1.5	0.1	1	20	576	595	576	597	0.84
8	17	3.3e-05	0.0024	18.1	1.1	1	23	616	640	616	640	0.91
9	17	0.12	9.2	6.8	0.5	3	21	647	665	647	666	0.90
10	17	0.07	5.3	7.6	0.5	1	23	685	710	685	710	0.95
11	17	0.67	50	4.5	1.9	2	23	728	750	727	750	0.94
12	17	0.0039	0.29	11.5	0.1	2	23	756	778	755	778	0.92
13	17	0.009	0.67	10.4	0.1	2	23	782	804	781	804	0.95
14	17	4.8e-05	0.0036	17.5	2.0	1	23	810	832	810	832	0.98
15	17	0.0098	0.73	10.3	1.4	1	23	836	859	836	859	0.93
16	17	3.8e-05	0.0028	17.9	1.8	1	23	865	888	865	888	0.96
17	17	4.6e-06	0.00034	20.8	0.7	5	23	901	920	892	920	0.85

Sequence Information

Coding Sequence: ATGTcggaaaacccaaaaacaagACGCAGCGGTCCTAGCTGCCTGCATTGTAGCGCATTCGGTGGCAAATTGAAGTACCAGGAGATATTTGATGAGTTTGGTCTGGAACTGGGACTCCAAGAGCTGCTGGCGAAGCACTTCAACATAGATGTGACGCCCAACgcaaagcagcaacagctcctTTGCGATGAGTGTGTGAATGTTCTGATCCGATTATTTGACATTGACGAGCTACAGAAAGAACAGGATGCTGCagttgccaaaaaaaagtgCGCTGACCaggctgctcctgctccaaaGAGTTCACCCAAGACGCCTCCAAATGCTGCAAAGAATGCATCCAAGACGGCTCCAAACGCTGCAACGAGTGCATCCGACACGGCTCCAAATACTGCAAGGCCTGTCAAGCCTATGGCAAAAAAGGGCACACTGTCGGAGCCACAAACCAAAGTGGAAAAGCCTGCGCCAGTGGTCCAGCCGGACCCGAAACCCAGCCGACgtataattaaaaatgtatccGTGCCACTGCCATCTGCTGCCTCCGTATCAACCGCAGTTGATAATGTCAAGGCACCATCTAAAACTAAGCATGCTCCGAAGGAGGCAGACCAGGAGCAGATTAGTGCCCTCATTCTCAATATTCTAAACGAGGACGAGCCGGGCGTGGAAGATGAGGCAGAAACAGTTCTTCCCGACTCTCCCCAAAGACCAGCAGCAAACACAAGTCGAACAACAATTGCTGTGCTAAAAAATGAAGCGGCGGCTGAGGCTGAAGCTGAGGTGACCGAAGAAGAAGATCTAGATGGAATGAATATCATATACGAGCATGAAGATATTTTAATTGAAGAGGAGGTAAATACAAAGCCAGACATCCGTCCATCCAGACTAAAAAGGCAGAAAACGGAGAGCCAGAGCGAGGCAGACAACGAGGAGAGCAATATTGTCCTCTTTAACTTTGTCGAGATCAAAGAAAAGGATGACATTGACGACTTATACGAATACTTGGCCACGGTGGTGAGGACCAGCTTTGAGAATCTAAAGTTCAAGTGGAGCACTGTCTGCCAACTTTGCACATTAAGGTCCGCTAGCTACGAGAACCTGCTGGAGCACATGCTGAAGGTGCACAAGTCCCGGTCGGATGTTTTTCGGTGCCCAATCGAGGGCTGCAGCTTGGAGCTAAAAGGAAGCAATCTCCTGGCCATGCATTTGGTGGTCCTGCATGCGCCTGTGGCTGATATTGCCATTTACGGCAGCTGTCCGGAATGCAAGATGACATTCTCAAATATTTTACAGTACAATAAACATTCGTGTGCGCATATCATCAAGAAAAAAGAGGCGTTCGCTTGTTTTGCGAAATGTGCGCTCTGGAGTTTCCCTCCTGGAAGCGATTCAATTTTCACAATCAATTCCACTTGGAGAAGCACCGACCGCCATTTGCATTATTCCCACGAGCTAGAGGGCACACTCTTCTGTGATCTTTGCGATCGCACGTTCCGGGATCCCGCTGTCTTCATAGAGCACACCACGTCGCATGCGACTGTGGGCGACGCCACCTACACCTGCGGCGAATGCCTGGCTACCTTCGAGACTCGTGGCAAACTAAATAGCCACACGAGATCAATGCATGGCAACGTCATCAGCTGTGAGCTCTGCTCCCGCGAGTTTGCCTCTGAGACCACATACAACGTCCACATGAAGTCACATTTGATTATCGAAAGGGAAGTTCATGTCTGCGGCAATTGTGGCCAACTGAGCGAGAATCAGGAGAAAATGGACGTCCACTTGGCGACCGAGGGCTCTGCCTGCTTTGGTGCGGAGAGTTACGTGGAAATGCGACGCGATGCCTTTGTCTGTGAATACTGCACTACGTACTTTAAGCAGAAGTCGGACTTACAGTCCCATCGCGAGACGGGTGTGCACAACAACGGGGTTTTTTGGTGTGAGCCTTGCGGAAAGGATTTTACCGACATGAAATTGTATCGTCACCATTGGCGCAACTATCAACAACTGCGAGTAGATGTTGCACATCGGAAGCTGGACATTTGTACCTACTTCATGTGCGACCAGAAGGACTGCTTGGCGGCATATGCGAACTGGAACTCACTGTACACGCACAAGCGACGCACGCACGATGAGTCCAAAGAGCAGAAGGAGAAATCGGCCAAGCCGCTTCAGGAATGGCAATGCCAATTCTGTCTTAAGCTATGCCGCTCGAAAATGTCCTTATCCGTCCATGTCGCCCGGAGCCACAATAATGACAATGTGGTCTGTTCACTGTGCAACGCCTCGTACAAGAGCAAGGATGCCCTGGACAAACACTATGCTTACTGGCACGAGCCCATCGAGTGCCCGGAGTGCTTCAAGATAGTCAAGAACAGGCGCAACTACGACACCCACGTGAATGTGGTGCACTCAAACAAAAAGCGCTACACCTGCAGTGTGTGCGAGAAAGGCTTCTACCACAAGAGCGAGATGGAGGCTCACAAAAGGCTCCATTCGCAGTCGTACAGTTGTGAGCAGTGCAGCTTCACCACCAGGAACAAGAAGTCACTGTCTGTTCATACCCTGGGCCAGCACTTTAAGCGATTCGCCTTCGCCTGCAAGATGTGCGACAAGCACTTTGGTCGACGCCAGGGACTGACCAACCACATACAACGTGTGCACGCCTCCAAGCATGTGTGCCGTAACTACATTGACGACGGCTGCGGGCGTTCGTTTACCACCAGTTCCCAGCTGAACGTGCATTTGCGCAAGGTGCACAACTCCACTTTAGTAGCCGACGATGTGCTCGAGGAGGAGGCGTATGCCATCGCCAGACCGCCAGCAGCGAAGAAACGTTGCTTTGGAATTTTGAAAGATAAAAAAGTTGAGTTCTTAGACGATTCTGCTGTTGATATGGACACGATGAAAGACGCTGATTATAACGTTatagaggaggaggaggaggaagaggaagaggaggagatgGAGCAGGAGGATGAAGAATGTGAGCTAGAATTTGCCGAGGATGAGGCAGAGGGGGAACCGAAACCGAACCCCGGCTCAGACAGAAAACATGGAAGAAAACACCGTTCGGATGATTAG
Protein Sequence: MSENPKTRRSGPSCLHCSAFGGKLKYQEIFDEFGLELGLQELLAKHFNIDVTPNAKQQQLLCDECVNVLIRLFDIDELQKEQDAAVAKKKCADQAAPAPKSSPKTPPNAAKNASKTAPNAATSASDTAPNTARPVKPMAKKGTLSEPQTKVEKPAPVVQPDPKPSRRIIKNVSVPLPSAASVSTAVDNVKAPSKTKHAPKEADQEQISALILNILNEDEPGVEDEAETVLPDSPQRPAANTSRTTIAVLKNEAAAEAEAEVTEEEDLDGMNIIYEHEDILIEEEVNTKPDIRPSRLKRQKTESQSEADNEESNIVLFNFVEIKEKDDIDDLYEYLATVVRTSFENLKFKWSTVCQLCTLRSASYENLLEHMLKVHKSRSDVFRCPIEGCSLELKGSNLLAMHLVVLHAPVADIAIYGSCPECKMTFSNILQYNKHSCAHIIKKKEAFACFAKCALWSFPPGSDSIFTINSTWRSTDRHLHYSHELEGTLFCDLCDRTFRDPAVFIEHTTSHATVGDATYTCGECLATFETRGKLNSHTRSMHGNVISCELCSREFASETTYNVHMKSHLIIEREVHVCGNCGQLSENQEKMDVHLATEGSACFGAESYVEMRRDAFVCEYCTTYFKQKSDLQSHRETGVHNNGVFWCEPCGKDFTDMKLYRHHWRNYQQLRVDVAHRKLDICTYFMCDQKDCLAAYANWNSLYTHKRRTHDESKEQKEKSAKPLQEWQCQFCLKLCRSKMSLSVHVARSHNNDNVVCSLCNASYKSKDALDKHYAYWHEPIECPECFKIVKNRRNYDTHVNVVHSNKKRYTCSVCEKGFYHKSEMEAHKRLHSQSYSCEQCSFTTRNKKSLSVHTLGQHFKRFAFACKMCDKHFGRRQGLTNHIQRVHASKHVCRNYIDDGCGRSFTTSSQLNVHLRKVHNSTLVADDVLEEEAYAIARPPAAKKRCFGILKDKKVEFLDDSAVDMDTMKDADYNVIEEEEEEEEEEEMEQEDEECELEFAEDEAEGEPKPNPGSDRKHGRKHRSDD

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00580943;
90% Identity: -
80% Identity: -