Dlow001645.1
Basic Information
- Insect
- Drosophila lowei
- Gene Symbol
- Paris
- Assembly
- GCA_008121275.1
- Location
- CM017779.1:18336851-18338182[-]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 12 0.0014 0.1 13.0 1.6 5 23 108 126 106 126 0.95 2 12 1.5e-07 1.2e-05 25.4 3.4 1 23 132 154 132 154 0.99 3 12 2.2e-06 0.00016 21.8 3.6 1 23 159 181 159 181 0.99 4 12 4e-07 3e-05 24.1 4.9 1 23 187 209 187 209 0.99 5 12 1.2e-06 8.7e-05 22.6 2.5 1 23 215 237 215 237 0.98 6 12 0.00019 0.014 15.7 7.3 1 23 242 264 242 264 0.97 7 12 4.1e-05 0.0031 17.8 1.2 1 23 270 294 270 294 0.97 8 12 8.9e-06 0.00066 19.8 5.5 1 23 300 322 300 322 0.98 9 12 1.5e-06 0.00011 22.3 1.8 1 23 328 350 328 350 0.99 10 12 0.00058 0.043 14.1 10.0 1 23 356 378 356 378 0.98 11 12 3.5e-07 2.6e-05 24.3 1.8 3 23 385 405 384 405 0.99 12 12 4.9 3.6e+02 1.8 0.8 13 23 413 423 411 423 0.86
Sequence Information
- Coding Sequence
- ATGGAGGAAATATGCAGAGTTTGCATGGGAACGTCCGGAACATTCAGGAACATTTTTGATGAGACACAGAAATGGGACACCACTGGCATTGCTGACATGATATCAGAGTGCACCGGGTACGTGGTTGGGCGAGGTGATTCCCTACCCGAAAACATATGCCCGCCTTGCCTTGAGGACGCAGTGAGTGCCTTCGATCTTAAGAGAACCTGCCAGCGGAGCCATATTCTCTATTTCGAACTGATGGAGGAGGACAAAGAAAAAGCGCTCTGTGAAAATATAGAAGCCAAAGACTGGGAACCGTCAGATAGTGAGAGTAAGCAAGAGTGCACAAAATCCTTTAAAAAAACATCCCACCTCATTGCACACAGCCGTGGGCACTCTGGGGAGCGACCGTTCAAGTGTCCAAACTGCTCGAAGTCTTTCTCTCAATCCGAACTTCTCCGGAATCACATCTGTACTCACACAGATGAGCGATACCAATGCGCTCACTGTTCGAAGTCATTTAAACAGAAATCGCAGCTCGTCGGACACAGCCGTACTCACACGGGAGAGCGACCGTTCAAGTGTTCGCAGTGCTCAAAGTCTTTCACTCACGCCACAACACTCCGGAATCACATCCGTACGCACTCTACCGAGCGGCCGTTCCAGTGCAGCCACTGCTCCAAGAGCTTTGGCACACCCGGCAATCTCCGGGATCACAAGCGGTTGCACGAGGATGATTCATTCCACTGCTCTCACTGCTCAATGTCCTTTAAGCGAAAAGCCTCTCTAGAAAGACACACCTACAAGCACACGGGGGAACGGCCCCACACATGCCCCGAACCCAAGTGCCCAAAGTCATTTCTGGAGAAGTACGACCTCAAGAAACACATGATCACGCACCTGCCGGAGCGACCGCATAAGTGTTCGCAATGCGACAAGACCTTTTGCCAAGCCCAAACTCTCCGGGTACACCTCCGTTTGCATACCGGCGAACGACCCTACCAATGCTCCCAGTGCTCGATGTCCTTTCCACAAAAGTTCAATCTTGAAAGGCACACCCTCACGCACACGGGGCAACGACCCTACCATTGCCCACACTGTCACAAGACATTCAAACAGCAGTCCCATCGCGACATTCACGTACAGACTCACGATGGGAAGCGACATGGGTGCACACTCTGCCGAAAGACCTTTTCACGAGCCAGCACTCTCCGGAATCACATCCGTACTCACACGGGAGAACGACCTAACCAAAAACTCCAACTCAAACTTCATGTACGTACGCACACAGAGGAGAACAAGGACCCATCCAGTGTGTCCACTGCGATTCCGGAGGACAAGGAAATTTAG
- Protein Sequence
- MEEICRVCMGTSGTFRNIFDETQKWDTTGIADMISECTGYVVGRGDSLPENICPPCLEDAVSAFDLKRTCQRSHILYFELMEEDKEKALCENIEAKDWEPSDSESKQECTKSFKKTSHLIAHSRGHSGERPFKCPNCSKSFSQSELLRNHICTHTDERYQCAHCSKSFKQKSQLVGHSRTHTGERPFKCSQCSKSFTHATTLRNHIRTHSTERPFQCSHCSKSFGTPGNLRDHKRLHEDDSFHCSHCSMSFKRKASLERHTYKHTGERPHTCPEPKCPKSFLEKYDLKKHMITHLPERPHKCSQCDKTFCQAQTLRVHLRLHTGERPYQCSQCSMSFPQKFNLERHTLTHTGQRPYHCPHCHKTFKQQSHRDIHVQTHDGKRHGCTLCRKTFSRASTLRNHIRTHTGERPNQKLQLKLHVRTHTEENKDPSSVSTAIPEDKEI
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- -
- 90% Identity
- -
- 80% Identity
- -