Dlon012634.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Drosophila longiperda
Gene Symbol
-
Assembly
GCA_035042125.1
Location
JAWNLV010000135.1:52646-56073[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 12 0.01 0.69 10.5 0.4 2 23 143 165 142 165 0.90
2 12 7.2e-06 0.00048 20.4 0.4 2 23 179 201 179 201 0.94
3 12 0.36 24 5.6 8.8 2 23 465 486 465 486 0.97
4 12 1.2e-06 8.1e-05 22.8 2.8 1 23 492 515 492 515 0.96
5 12 0.00055 0.037 14.5 0.7 1 23 520 543 520 543 0.96
6 12 6.2e-05 0.0042 17.4 5.5 1 23 561 583 561 583 0.96
7 12 0.00013 0.0084 16.5 1.6 1 23 588 610 588 610 0.98
8 12 3.3e-05 0.0022 18.3 1.7 1 23 616 638 616 638 0.95
9 12 2.3e-05 0.0016 18.8 0.7 1 23 644 666 644 666 0.98
10 12 3.4e-07 2.3e-05 24.6 2.7 3 23 674 694 673 694 0.99
11 12 2.3e-08 1.5e-06 28.3 1.0 1 23 700 722 700 722 0.99
12 12 1.5 1e+02 3.6 5.2 1 19 727 745 727 750 0.88

Sequence Information

Coding Sequence
ATGCCTGACATTTATGGTCAGTTCGATGCGGAGCGCGTCTGCCGTGTTTGTCTGCGCGAAGTGGGCGATTTTTACTTTATCTACGACGAAGCGCCCGTGGAGCAGGGTGCAAACATCGCTCAGATACTCAATGAATGCACACGGTATACGTGTGAGCGTTACGACAAGATGCCGCATAACATGTGTGACACCTGCATCAAGGCCGCCTGCCAGGCGTATCGCTTCAAGCGGGACGCTGAAAAGGCATATCGCTCGCTTGTTGACATATTGGGCCGCACACCCGTTAGCAACCCGAACAGTACAGATATGTGCACTCAGACTGAACAGCTGCCCATGCTGCCGTGCGGCATCTGCAACGATATGTTCTTAAGCATTATTGAAGTGCGTCTGCATAGGAATCGCCAGCACAAGAACATAGCGGAGCTCAAGTGCAAACTGTGCGACGAGAAATTCGAGGAATTGCGCCAGCTGCTTAACCATCTCGTAGAGCGACATGATCCCAAGTCGGCCACATCGTTTTTGCGTCGCCGTCGCGAATGTCGCGACTGCCAACGCGTCTTCTCGCGACGCGATCTTTTGCTCCGTCATATGCAGGCTGTCCACAATGTGGTAGGCCGGGGTCGTCACTGGACGCTGGCCGCGGAGCAGGAGGTGCAATCTGAAACGTGGCCGCCTGTCGACGAAGCAACCATGCACAGCGCCGACTTATTTAATGAATCAGCTGCGTGCTCCGATGACGAGAATGACAAAACTAATAATGAAATGGGCTATCAACGTCATACGAATCCCATATCAAGCAACGACGACACTGAAGATGAAGAGATCCATGCGGAGGCTAAGGAATCTCTGTGGCTGCACATTAAGCCAGAACCGGAAGCTGACCTCGATCCGTATCCGGAGTCATTTGTATCACCTGTAAATCGCGTGATGCGccgcaaaaaaacaaatatagaaCGTGCCACCCACATTAACGAGAATGAAGGATTGAACATCAAGAAAGTTGCGAGCAGTGATTTGGAAGCAGAGGTAAAAGAAGAGCCACTGGTCACGGGCAGCGAGCAAGTGTTACCGATTAAGCTGGAACGCCAATGCACTGATAGTGTCAATGAGGATGGTGAGTATGAGATGGACGCTGGATCAGCCAACATTTATCAAAGCGCCGATGAGGAGGACGGCGAGGAAGAGTTTGTCAATGACGAAAGCGACATTGATGAATACGACGACGAAGATGACGACTATCCGGGTGCCGAGCAAAAGCAGCGATCGGAGGACAAGTCCAAACAAACCCAAGCGAAAACTGTGCGCGACTATCTGCAGAAGCCGACTGCTGGCAAGCAGTGCCGTCGTCGCCGAAAAAAGCAGAGTGATTCTGCGGCACCCAACCCGGAGAATCGATGCGATGTCTGCATGCGCACATTTTCCCGCCACTGTCACTTGTTGCGCCACAAATTGTCGCATTTGGAAAAGAAACCGCACAGCTGTCCGCATTGTCCCAAGGCGTTTGCGCGCAGCGATCATTTGAAAGCGCACGTGCAAAGTCTGCATGGCAACAAGGAGCACAAGTGCGTGCTGTGCGAGGCAGCATTTTCCCGCCTTGATGCCCTCGAGCGGCACAAGATGAGCAAACACAATGGCGAGGGCCTGGACGCCAGCAGCGAGCTTAAACTGCAGATGAGCGAGCATACCTGCGAATACTGCTCTAAGCGATTCTCAAGCAAGACCTACCTGCGCAAGCACACGCTACTCCACACGGAATTCCTTTATGCGTGTAAGAGCTGCGACGAGACATTCAAGGAGCGCCAGCAGCTGCGCAGTCACGAGAAGACTCACACCGGTCAGCGCAATTTTCTCTGCTGCATTTGCGGCGATAGTTTTGCGCGCAACGATTATCTGCGCGTCCACATGCGTCGACATAATGGCGAAAAGCCTTACAAGTGCCGTTATTGCGTCAAGGCCTTTCCACGCGCCACGGATCTTAAAGTTCATGAGCGCTATCACACCGGCACAAAGCCCAATCTGTGCAATACTTGCGGCAAGAGTTTCCACCGCGCATACAATCTGACCATACACATGCGCACTCATACTGGCGAACGCCCCTACAAGTGTGACCAGTGCCCAAAGAGCTTCAGCCAGAGCAACGACTTGAAGGCGCACATACGACGTCATACTGGTGAGCGCTACAAGTGCCCGCATTGCGATGCCTACTTTCTGCAGCTTTACCATATGCGCAATCATTGCCTCAGTGCCCATAACAAGCACATTGAGACTAAAACTGGTCGGCTACAGCGCACTGGTCTGTTGGACGAGTCCAGTCACACGCATCTTACCACTGTGGTCATGCCCGCAACACGTTCGCATTCATCAACGGGAGATCCGGCAGCGACAGTTGGCACACAATTGCCTGCATCGTCGACAGCGCCGGCGACGATTGCAACGACAATTATGCATTCCCCGGTGACATACAACATAGCATCGCCAGCATCAGTGTCGGTGCCAGCGCCGGAAGCCGCCGGATTTATAGGTGTAGCGAATAATGCAAGGGTGACGGCAACGGCCACGCCACCATTTGCGGCATATAATATACCTCCCGTGGTTATGGCGCATTTAATGTACAATCATGGCAGCAACAGTCAGCAGAGCAATGTCAGCGGCAGCGAAACCGGGAAATAA
Protein Sequence
MPDIYGQFDAERVCRVCLREVGDFYFIYDEAPVEQGANIAQILNECTRYTCERYDKMPHNMCDTCIKAACQAYRFKRDAEKAYRSLVDILGRTPVSNPNSTDMCTQTEQLPMLPCGICNDMFLSIIEVRLHRNRQHKNIAELKCKLCDEKFEELRQLLNHLVERHDPKSATSFLRRRRECRDCQRVFSRRDLLLRHMQAVHNVVGRGRHWTLAAEQEVQSETWPPVDEATMHSADLFNESAACSDDENDKTNNEMGYQRHTNPISSNDDTEDEEIHAEAKESLWLHIKPEPEADLDPYPESFVSPVNRVMRRKKTNIERATHINENEGLNIKKVASSDLEAEVKEEPLVTGSEQVLPIKLERQCTDSVNEDGEYEMDAGSANIYQSADEEDGEEEFVNDESDIDEYDDEDDDYPGAEQKQRSEDKSKQTQAKTVRDYLQKPTAGKQCRRRRKKQSDSAAPNPENRCDVCMRTFSRHCHLLRHKLSHLEKKPHSCPHCPKAFARSDHLKAHVQSLHGNKEHKCVLCEAAFSRLDALERHKMSKHNGEGLDASSELKLQMSEHTCEYCSKRFSSKTYLRKHTLLHTEFLYACKSCDETFKERQQLRSHEKTHTGQRNFLCCICGDSFARNDYLRVHMRRHNGEKPYKCRYCVKAFPRATDLKVHERYHTGTKPNLCNTCGKSFHRAYNLTIHMRTHTGERPYKCDQCPKSFSQSNDLKAHIRRHTGERYKCPHCDAYFLQLYHMRNHCLSAHNKHIETKTGRLQRTGLLDESSHTHLTTVVMPATRSHSSTGDPAATVGTQLPASSTAPATIATTIMHSPVTYNIASPASVSVPAPEAAGFIGVANNARVTATATPPFAAYNIPPVVMAHLMYNHGSNSQQSNVSGSETGK

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00620004;
90% Identity
iTF_00511432;
80% Identity
-