Basic Information

Insect: Drosophila littoralis
Gene Symbol: ush
Assembly: GCA_018903485.1
Location: JAEIGF010000349.1:2897722-2916725[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 9 0.0062 0.39 11.1 0.0 1 20 174 193 174 195 0.90

2 9 0.00027 0.017 15.4 0.8 1 23 254 276 254 276 0.98

3 9 0.048 3 8.3 1.0 2 21 317 336 317 337 0.92

4 9 0.047 2.9 8.3 2.9 2 21 723 742 722 743 0.93

5 9 0.0086 0.54 10.6 0.0 3 21 793 811 791 812 0.91

6 9 0.018 1.1 9.6 0.0 2 23 881 902 880 902 0.98

7 9 0.0036 0.23 11.8 1.3 1 23 908 930 908 930 0.99

8 9 0.0013 0.08 13.2 1.9 1 23 986 1009 986 1009 0.96

9 9 0.29 18 5.8 0.7 2 20 1115 1133 1114 1135 0.91

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	9	0.0062	0.39	11.1	0.0	1	20	174	193	174	195	0.90
2	9	0.00027	0.017	15.4	0.8	1	23	254	276	254	276	0.98
3	9	0.048	3	8.3	1.0	2	21	317	336	317	337	0.92
4	9	0.047	2.9	8.3	2.9	2	21	723	742	722	743	0.93
5	9	0.0086	0.54	10.6	0.0	3	21	793	811	791	812	0.91
6	9	0.018	1.1	9.6	0.0	2	23	881	902	880	902	0.98
7	9	0.0036	0.23	11.8	1.3	1	23	908	930	908	930	0.99
8	9	0.0013	0.08	13.2	1.9	1	23	986	1009	986	1009	0.96
9	9	0.29	18	5.8	0.7	2	20	1115	1133	1114	1135	0.91

Sequence Information

Coding Sequence: ATGACCGTCGACAGCAGAGAATCCAAAGATTTGGGCGCACACGAGCTTAGCGAGGAGAAACAGCAGCCGCAGCAGCAGCCCGAGGACGAGCAGCTCGAGAACCAAACCAGCAACGCCTCCGAACAGCCCGAGGAGACTGACATGGATCAGGACATGGTCGAGGAGGCCCAGGCAGCGCAGGAGGCCAGCGCCAGTGTGGCCGACAGCTCGACGACGCCACCGCGTAGTCCCACGCCCGAGCTGGTTCCCAAGCTGGAGCGAGCTGATACGCCGGTGACGCCGCCTTCAGCGGCAGCCACGCCCAGCCCACCGGCAACGCCCACGCCGCCCACAATGCTGCCCAAGCTGCGTCTGAATGCTTTGCTCGCATCCGATCCGGCCCTAAAGCCGGACGCCAAGGAGCTGCATCCGCACGAGCCACGCCTGCTGGCGCCACCGCCGCAGCTGGCCAAGACCGAGCAGCAACAGATTCTGCCCGATGCCAGCAGCCTGGTGGAGCCGCTGCTGAAGCCGGCGCGGTTTATGTGCCTGCCCTGCGGCATTGCCTTCAGCTCGCCCTCAACGCTGGAGGCGCACCAGGCCTACTATTGCTCGCATCGCAACAAGGACGCCGACGAGGAGACGCCCGCCGGCGACAAGTCGGCATCCGGTACAGCAGCTGGCTCCAGCGCCGGCAACGGCAGCAATGCCAACAGCAGCTCCAGCGGGGGCAGCTCTGGCTCGGAGCCAGCGGCCAAAATGGCGCGCACGGGCAAGCAATACGCGTGCACGCAGTGCTCCTACAGCGCCGACAAGAAGGTCTCCCTCAATCGGCACATGCGCATGCACCAGACCTCGCCGGCGGCGCCCAGCCTCAATAGCCTCAACAACCTGGTGGCCAACGGCGGGGTTGGTGGCGTTGCCACGGCCGGCGCGCTCGAGGAGAGCTCTAGTCAACAAATCGATCGCTACTGCAGCGACTGTGATATACGCTTCAACAACATCAAGACCTACCGCGCCCACAAGCAACACTACTGCAGCTCCCGGCGCAGCGACGGACAGCTGACGCCCAAGCCGGAAGCTGGCGCCGGCACGGCCGGCGGCGGCTCCGCAGCAACAACAGCTCCAACTGCCGCTGCAGCGGGCAAGCACAGCGGGCCGGCCGCCCACAGTCCGCAGAGCACGCGCAACAAGACGCCCACGCCGGCAATGNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNCCACCAATCCCATCATCATAGTGCCCTGCTCGCTCATACGCGCAGCCAGCCTAATACCGGGACCACTCACCACCTCCACGTCGGGCATTGTCAATCCGGAATCCACGTGCTTTACGCTCGACAATGGCGCCCTCAAGCCGCTGGCCACGGCGCTCAATATAAATGCGCTCACGGGCAATGCCACGCCCACGGCCACGCCCAATCCTATGGGCAGCAACAGCAGCCAGCAGCAGCTGGGCCTGGCCGCACAGGAGCCAGAGCGTCCAAGCGGCATGGAGCCGGAGCCCAAGAGCAGTCCTCCGGAGCCCAAGCGCAAGGAAGCCGCCGGCACACGTGAGACCACGCCGCTGGATCTTTCGCTGCGTCGCTCGCCAATCGCCGCGCTGCTGCAGCGTCAGCGTCTGGTGCGCTCCGCCGCGCTGCTGGACGCCGAGGAGGCGCTCCTGGGCGCTGCCAAGGAGAACCTGGAGACTGGCGGTGGCAGCGTCACGCCGGAGCAGATAGTGTGCGCGCCCTCGCTGCCCAGCAGCCCCTCGATGAGTCCTTCGCCCAAGCGACGAGCCCTCAGTCCGCGCAGCTCGGGCGCCGGCAGCGCTGCCTCCATGTCGCCGCCGGCGCTGGGCGTGGCCGTGCCACATCATCTGCTGGACCAGCTGCCGCCGTTGCGCTCCATGCTGCCGGCGGACTTTGCGCTAACCGAATCGCTGCTGGCCAAAACGAATCCCGAGCTGGCGCTCAAGCTGGCAGCCGCCGCCGCCGCAGCCGTTGCGGGTAGCAGCAGCAGCGCCGAACTGGCCACCAAGCTGGGCTTTCCCGCGAGCGCCGCTGCCAACAGCGTCGCGCCCGGCGGCCAGCAGCCGCAGATCTATGTCAAGCAGGGCGTCTCCAAGTGCAAGGAGTGCAACATTGTCTTCTGCAAGTACGAGAACTATTTGGCCCACAAGCAGCACTATTGCTCCGCGCGCAACCAGGAGCCGGCCGGCGAGGCTGATCCCAAGATCGGCGCGGTGACGCCGCCCGCAGTGGCGGACCGCAGCGGACCTGCTGCCGGACCGGGCGGCGCAGAGACAACGCCCGTCGCCTACCAGCAACTCATATGCGCCGCCTGCGGCATCAAGTACACCTCGCTGGATAATCTGCGCGCCCATCAGAACTATTACTGTCCCAAGGGCGGGGCCGCAGCGGCAAGCGCGGCGGCGCCCGCCGAGGCAACGACTGTGCCCCAGCTGAAGGAGAAGTGCGGTAAGTGCAAGACCCTGCATGAGCCGGCCCAGCCCTGCGCGGTGCCGCCGCCGCCCTTGCCGGCAGCCACGCCCCAGCTGCCGCCCGCCGGAGTCGTTGCCGGCTCGAACAGCGTGAACAAGTGTCCGGTTTGTGGCGTCATCAGCCCGACCGCGGCGCTGGCGCGCAAGCACATGGAGATGCACGGCACAGTGAAGGCGTTCCGCTGCAGCATCTGCCAGTACAAGGGCAACACGCTGCGCGGCATGCGCACCCACATACGCACCCATTTCGACAAGAAGACCAGCGACGTCAACGAGGAGCACTACATGACCTGCATCTTCGAGGAGGATGCAGCCGGACAGGCAGCCGCTGCACAGCCGCCGCCGCCGCCAGCCCTGAGCCTGGATTTGCCCGGACAGGTCGAGCAGCTCGACCAGCATCCGGCACAGCTCTTTAACTGCGATCACTGCAACTATGCCTCCACCTACAAGGGCAATGTGCTGCGCCACATGAAGCTGCTGCATCCACACGTGGCCCTCAGTTCGCCCTCCATTTCGCCCGAGTCGCGCGAACTGGACCCCAATCCGCATGCCCTGCCCGAAGTAGCCCTGGTCAATGGCGAGCGCGAGGCCAGCTTCCACATCAAATCGGAGCCCTTGGAGCAGCCGGTGGCCACGCTGGGTCTGGTGCATGAGAACAACAACTCGCCGATTGGAACGCCCCATACGCACATCAAGGCCGAGCCGCTGGACATGGGCATGGAGCTGTCGACGCCCGCGCTGCCCCCGCCGATGGCCAACTCGCCGCTCGGCCCAAGCGCTGCGGAGGCCATGAAGAAATACTGTTCCACCTGCGACATATCGTTCAACTATGTGAAGACCTTTCTGGCGCACAAACAATTCTACTGCAAGAGCAAGCTGCATCGACCCGAGCCCAACGACAGCCCCAGTCCCACGGTGCTTGTTGCCGGCGGCGGCGGCGTTGGGATTGGTGGTGGTGTTGGGGGCAACAGCACCATGTTGCCGCTGCAGTCGCCCAGCGAGCTGCTCCTGCTGCAGAAGAACAAGGAGAACCTGCAGGAGGCGGCCATTTGA
Protein Sequence: MTVDSRESKDLGAHELSEEKQQPQQQPEDEQLENQTSNASEQPEETDMDQDMVEEAQAAQEASASVADSSTTPPRSPTPELVPKLERADTPVTPPSAAATPSPPATPTPPTMLPKLRLNALLASDPALKPDAKELHPHEPRLLAPPPQLAKTEQQQILPDASSLVEPLLKPARFMCLPCGIAFSSPSTLEAHQAYYCSHRNKDADEETPAGDKSASGTAAGSSAGNGSNANSSSSGGSSGSEPAAKMARTGKQYACTQCSYSADKKVSLNRHMRMHQTSPAAPSLNSLNNLVANGGVGGVATAGALEESSSQQIDRYCSDCDIRFNNIKTYRAHKQHYCSSRRSDGQLTPKPEAGAGTAGGGSAATTAPTAAAAGKHSGPAAHSPQSTRNKTPTPAMXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXTNPIIIVPCSLIRAASLIPGPLTTSTSGIVNPESTCFTLDNGALKPLATALNINALTGNATPTATPNPMGSNSSQQQLGLAAQEPERPSGMEPEPKSSPPEPKRKEAAGTRETTPLDLSLRRSPIAALLQRQRLVRSAALLDAEEALLGAAKENLETGGGSVTPEQIVCAPSLPSSPSMSPSPKRRALSPRSSGAGSAASMSPPALGVAVPHHLLDQLPPLRSMLPADFALTESLLAKTNPELALKLAAAAAAAVAGSSSSAELATKLGFPASAAANSVAPGGQQPQIYVKQGVSKCKECNIVFCKYENYLAHKQHYCSARNQEPAGEADPKIGAVTPPAVADRSGPAAGPGGAETTPVAYQQLICAACGIKYTSLDNLRAHQNYYCPKGGAAAASAAAPAEATTVPQLKEKCGKCKTLHEPAQPCAVPPPPLPAATPQLPPAGVVAGSNSVNKCPVCGVISPTAALARKHMEMHGTVKAFRCSICQYKGNTLRGMRTHIRTHFDKKTSDVNEEHYMTCIFEEDAAGQAAAAQPPPPPALSLDLPGQVEQLDQHPAQLFNCDHCNYASTYKGNVLRHMKLLHPHVALSSPSISPESRELDPNPHALPEVALVNGEREASFHIKSEPLEQPVATLGLVHENNNSPIGTPHTHIKAEPLDMGMELSTPALPPPMANSPLGPSAAEAMKKYCSTCDISFNYVKTFLAHKQFYCKSKLHRPEPNDSPSPTVLVAGGGGVGIGGGVGGNSTMLPLQSPSELLLLQKNKENLQEAAI

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00531237;
90% Identity: iTF_00563438;
80% Identity: -