Basic Information

Insect: Drosophila littoralis
Gene Symbol: -
Assembly: GCA_018903485.1
Location: JAEIGF010000406.1:98774-101298[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 8 8.6 5.4e+02 1.2 0.4 3 23 36 58 34 58 0.87

2 8 0.067 4.2 7.8 0.3 2 23 143 165 143 165 0.94

3 8 4.2e-06 0.00027 21.0 3.0 1 23 183 206 183 206 0.98

4 8 9.2e-06 0.00058 20.0 2.3 2 23 305 326 304 326 0.96

5 8 0.0039 0.24 11.7 5.8 1 23 332 354 332 354 0.98

6 8 1.2e-05 0.00077 19.6 1.1 3 23 362 382 361 382 0.99

7 8 1.7e-06 0.00011 22.3 3.0 1 23 388 410 388 410 0.99

8 8 0.00014 0.0085 16.3 5.3 1 20 416 435 416 437 0.95

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	8	8.6	5.4e+02	1.2	0.4	3	23	36	58	34	58	0.87
2	8	0.067	4.2	7.8	0.3	2	23	143	165	143	165	0.94
3	8	4.2e-06	0.00027	21.0	3.0	1	23	183	206	183	206	0.98
4	8	9.2e-06	0.00058	20.0	2.3	2	23	305	326	304	326	0.96
5	8	0.0039	0.24	11.7	5.8	1	23	332	354	332	354	0.98
6	8	1.2e-05	0.00077	19.6	1.1	3	23	362	382	361	382	0.99
7	8	1.7e-06	0.00011	22.3	3.0	1	23	388	410	388	410	0.99
8	8	0.00014	0.0085	16.3	5.3	1	20	416	435	416	437	0.95

Sequence Information

Coding Sequence: ATGTGCTCCATGTCCGTGCTGTGTCCGCTGTGCGCGGTGCCCAGTTTCAATAGCATCGATGCACTGCAGCAGCGTCTGATCAAGGCGGCGAATGGACCTTTGGCCTGCCCCTTTCCGCACTGCAAGGAGCTGTTCCTCGGCTTGGACAAGCTGACCATACATCTGTTCAGCCACACCAGCCTGATGCAGCAGCCCGTTGCAAGTGCAGCAGCTCCGCCAGCTGCAGAGCCTGCTGCTGCGCTTCCCCTACTGCCCCCAATCAAGCCTTGCCCCGCTGCAGCCAGTTCGCCGCCGCCGCCGCCAACGTCTTCGACTGTTGCCGCTGTGCCCAAGCGACGTGGCAAGAAGTCGCGTGCCAAGCCCTTGGAGCAGCCGCCACCAGTTGTGCCGCCGCCGCCACCGCCTGCGCCCGCGACGCCGCCAGCGAGATGCGACATCTGCGAGTTCAATTTTCGCAACGAAGAGCTGCGCGACATGCACATCCGGTTGGTGCACGAGAACGCGGAGCTGACGGAGCAGCAGCCGCAGCAGCCAAAGCAGGAGCCCTACAAGTGTCATCTCTGCTCCAAGACGTTCCGCATGAAGGGCTCGCTGCGTGTACATCTCAAGGTCCTGCACACGGTGGGAGCAACGCTCGGANNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNCTCAGTGCCACGCCCAAAATCAGCATTTGCGATCGCATCCGGCACAAGGAGGCATCCGCCAGCAGCGGCGCCTCCTCCACTGGATGCACCAACAGCCAACCGTACGCATTGAGCGGGGCCATTTGCATGCTCAAGCAGGAGCTGCCGGGAGCTGCAACGGATGCGGCGCCCGGCTCGGAGTACGGCAGCACGCCCAAGAACTGGGAGTGTGATGTGTGCACCAAAATGTTCACCACCAAGTATTTCCTGAAGAAGCACAAGCGGCTGCACACGGGCGAAATGCCGTACACGTGCCAGTACTGCGCACGCACCTTCACCTTCCAGCAGTCCTATCACAAGCATTTACTCTACCACAGCGAGGTGAAGCCGCACGGCTGCAGCATCTGCGGACGCGCCTTCAAGGAGCTGTCCACCCTGCACAATCACCAGCGCATCCACAGCGGCGAGAAGCCCTTCAAGTGTGAGGTTTGCGGTAAATGTTTCCGACAACGCGTCTCCTTTCTGGTACACACACGCATTCATACTGGAGTCATGCCCTACAAATGCGAGCACTGCCAGAAGACATTTCGCTACAAGGTCTCGTTGCGCACACATAAATGCGCTGCCAATACGGAGGACGAGCCACAGACACCAGAGCAACTGATCAAGGCGCTGCTGGAGTCCTCCAATGTGACATTGGGCCATGTGCAGACAGAGCATGTGGCTATTAATGCGGCCATTCAGATGAATGGCGGGGATCAGGAGGCGTTGCTCTCGCAAAGCATTGATGACATTGTGGTCGAGAGCTGCCAGAAGCTGGGCATTTGCAGCGTGGAGCCGCCACAGCAGCCACAGCCGGTGATCATGAACAGCAGCGTGCACTTTGATGGCAGCAGCTCGCCGCTGCAGCAGCTGCAGAATTTGCGACTCTATTCGCCGCAGCAGGCGGAACAGCCCAACAGCTCGGATGGTGAGCTCTTTCGCCATTTCCTAATGGACGCCACGTAG
Protein Sequence: MCSMSVLCPLCAVPSFNSIDALQQRLIKAANGPLACPFPHCKELFLGLDKLTIHLFSHTSLMQQPVASAAAPPAAEPAAALPLLPPIKPCPAAASSPPPPPTSSTVAAVPKRRGKKSRAKPLEQPPPVVPPPPPPAPATPPARCDICEFNFRNEELRDMHIRLVHENAELTEQQPQQPKQEPYKCHLCSKTFRMKGSLRVHLKVLHTVGATLGXXXXXXXXXXXXXXXXXXXXXXXLSATPKISICDRIRHKEASASSGASSTGCTNSQPYALSGAICMLKQELPGAATDAAPGSEYGSTPKNWECDVCTKMFTTKYFLKKHKRLHTGEMPYTCQYCARTFTFQQSYHKHLLYHSEVKPHGCSICGRAFKELSTLHNHQRIHSGEKPFKCEVCGKCFRQRVSFLVHTRIHTGVMPYKCEHCQKTFRYKVSLRTHKCAANTEDEPQTPEQLIKALLESSNVTLGHVQTEHVAINAAIQMNGGDQEALLSQSIDDIVVESCQKLGICSVEPPQQPQPVIMNSSVHFDGSSSPLQQLQNLRLYSPQQAEQPNSSDGELFRHFLMDAT

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00516486;
90% Identity: iTF_00563392;
80% Identity: -