Basic Information

Insect: Drosophila littoralis
Gene Symbol: pita
Assembly: GCA_018903485.1
Location: JAEIGF010000124.1:5472064-5474281[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 9 0.0055 0.35 11.2 0.2 1 23 283 305 283 305 0.87

2 9 1.9e-06 0.00012 22.2 2.0 1 23 311 333 311 333 0.94

3 9 1e-06 6.4e-05 23.0 2.7 1 23 339 361 339 361 0.99

4 9 0.00051 0.032 14.5 0.4 1 23 367 389 367 389 0.96

5 9 0.0002 0.012 15.8 0.1 1 23 395 417 395 417 0.95

6 9 4.3e-05 0.0027 17.9 0.3 1 23 423 445 423 445 0.94

7 9 0.0038 0.24 11.7 5.7 1 23 451 473 451 473 0.98

8 9 0.016 0.99 9.8 0.0 2 23 509 530 508 530 0.95

9 9 0.0066 0.41 11.0 0.8 1 23 536 559 536 559 0.91

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	9	0.0055	0.35	11.2	0.2	1	23	283	305	283	305	0.87
2	9	1.9e-06	0.00012	22.2	2.0	1	23	311	333	311	333	0.94
3	9	1e-06	6.4e-05	23.0	2.7	1	23	339	361	339	361	0.99
4	9	0.00051	0.032	14.5	0.4	1	23	367	389	367	389	0.96
5	9	0.0002	0.012	15.8	0.1	1	23	395	417	395	417	0.95
6	9	4.3e-05	0.0027	17.9	0.3	1	23	423	445	423	445	0.94
7	9	0.0038	0.24	11.7	5.7	1	23	451	473	451	473	0.98
8	9	0.016	0.99	9.8	0.0	2	23	509	530	508	530	0.95
9	9	0.0066	0.41	11.0	0.8	1	23	536	559	536	559	0.91

Sequence Information

Coding Sequence: ATGCACATGGCGTTGCCACTCTTGCCGCTGGCACAACCAGAGCGCATGCACAGTGTTGCCACACAAATCTGCTGGCCATTCACACTTAAACGTATTTATATTTGTTGTTATTATATTAAACAGGTCCAGAGCAATGATGGAATGCCCAGCTTTATCTGCCTGGACTGTCGTCTGCTCTTCGAGCACTGTTACCGTTTTAAGCAGATGTGTAAAAATGCGGAGACTCTACTCCGCCAATATCCGCTTACTGGCAAATGGCCAGAGCCGCTGGAGAAGCCGCGTGCGCCGCTGGTGGCCAATCAAACGGTTGCAGTTAAGAAGGAACATGCCGAAGCGCAGCCCAAAAAGCTGCTCAATTCCATGGCCAAGTCCAATAATGTGCAAATTGAAAGCGTACAGGTTTTGGAAACGAGTTCGCTCACCAAAAAGCTACTCAATACGGGTGCAGTGAGCTCTGCTGAGCCGCCGATTCCGCCAAGAGGATCGCCGGCAAAACGCCAACCTTCAAAGTCATATCAGATGAAAGTGGAGAACAACCAGGAACTATCCATGGACGATGTGCACAATTTGTTAGCTGATATGGCTGAAGAGCTGGATGATCTGGACAACATAACACCAGCACCTGTAACGACGCCTTCGGCTGGCAAACCAAAAGTACTTAACAAATCGTCGATGCGGCTGCTTAACAAAGGTGCCAGCACCACCGTGGAACCACGCCTGGCCACGCCTCAAATAAAGCACTACGAGGACGGAAATGTGGCGCTTGTTACGGAAATACTTGATCCCGATGCAGTTGATGCGGCTGCGGATCCAATTAAAAATGCTGCGCCCGTGGCGACTAACGTCTTTCCGTGTCCGCATTGCGATCGCTCATTTCCACTGATGCAGCTGCTCGACATACATGTTGTGAACCACACACGTACGCGTAGCTTTCAGTGTCCGGAGTGCGACAAGAGCTTTTTCTCCAAGTACGATCTGCAGAAGCACAACTTTATACACACGGGCGAACGTCCGTACAAGTGCAGCGTCTGCGAGAAGGCCTTCACGCGTCGCGCTCTGCTGCATCGCCACGAGCGAACTCACACGGATGTGCCCAAGTTTATTTGCCTTTACTGCGAGAAGCCGTTTATTTCGCGCAAGGAGATGGAAAAACATGCCGAGCGCCATACCAAAAAGCGGCCTTTCCAGTGCGGCGTATGCCAGAAAGCGTTTGCCTTCAAGCAGGGTCTGGAGCGCCACGAGGTCATACATAGCACCAATCTACCGTTCTCTTGCCAGTATTGCAGCCGGAGCTTTGTGACCGCAGGCAAGTTGGCCCGTCACCTGGTTGCGCACGCCGGCAAACGCGTCTATCCCTGCAAGTACTGCTCCAAGTCGTATCTGCTGTCACATCATTTGTCGCGGCATTTGCGCATGCACAAGCAGGCGCCGGCGGCCTCATTCACGTGCAGCATTTGCAAGGATACGCACCAAACTTATGACAGTCTGGTGGATCACTCGGCTATTCATGCGGGCATCTCGCTAGTCTGTCCACTGTGTCAGGCGAGCATCGCCGACTTGGACAGCCTGGAGTCGCACATGGAGGCGCACAAGAAGAGCGAGCGGCACGCGTGCGAGTTTTGTGATTTTATTTTCCTCAGCTCGAGCCAATTGCAGAAACACATCGAAGACGATCATGTGGTGGACATGGTGCCCTATCAGAATGAAGGCGAATATGAGCAGGGAGTCAGCAAAGAAGAGGATGTCGCGGAGGAGTCCGAATTAATGGAGGAATTGCTAGGCGAGGAGCCAGAGTCGCCATCAAATAAATCCGCATCGCCAACTCAAGCAAAAATACGCAAACTAAATCCGGTTCCCAAATCGGAGGAAAGTGACAAAATCAAGCAAGAGTCGAAACCCAAGATAATTAAAGAGGAGCCAATTTCACCAGATAACTTAAAACGAGCCCGAACCTCAAAATCTCCTGCCGCTGCGTCCGTCTCACCGGAAAGCAAACGCCAGACGCGCAGGCAAGATACCAAAGAAAAAACTCAGAAGCCAAGCGATTCTGGTAAAAGATTGTCAAAGAAGGTTATTGCAGACCAGGGCAAGCCGAGCAGCAAGCCAAGGAACGCTAAGGCCGCCAGTTCTAAGCATCAAAGCACCAAGTAG
Protein Sequence: MHMALPLLPLAQPERMHSVATQICWPFTLKRIYICCYYIKQVQSNDGMPSFICLDCRLLFEHCYRFKQMCKNAETLLRQYPLTGKWPEPLEKPRAPLVANQTVAVKKEHAEAQPKKLLNSMAKSNNVQIESVQVLETSSLTKKLLNTGAVSSAEPPIPPRGSPAKRQPSKSYQMKVENNQELSMDDVHNLLADMAEELDDLDNITPAPVTTPSAGKPKVLNKSSMRLLNKGASTTVEPRLATPQIKHYEDGNVALVTEILDPDAVDAAADPIKNAAPVATNVFPCPHCDRSFPLMQLLDIHVVNHTRTRSFQCPECDKSFFSKYDLQKHNFIHTGERPYKCSVCEKAFTRRALLHRHERTHTDVPKFICLYCEKPFISRKEMEKHAERHTKKRPFQCGVCQKAFAFKQGLERHEVIHSTNLPFSCQYCSRSFVTAGKLARHLVAHAGKRVYPCKYCSKSYLLSHHLSRHLRMHKQAPAASFTCSICKDTHQTYDSLVDHSAIHAGISLVCPLCQASIADLDSLESHMEAHKKSERHACEFCDFIFLSSSQLQKHIEDDHVVDMVPYQNEGEYEQGVSKEEDVAEESELMEELLGEEPESPSNKSASPTQAKIRKLNPVPKSEESDKIKQESKPKIIKEEPISPDNLKRARTSKSPAAASVSPESKRQTRRQDTKEKTQKPSDSGKRLSKKVIADQGKPSSKPRNAKAASSKHQSTK

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00479656;
90% Identity: iTF_00563378;
80% Identity: -