Basic Information

Insect: Drosophila littoralis
Gene Symbol: -
Assembly: GCA_018903485.1
Location: JAEIGF010000297.1:733244-735927[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 10 1 65 4.1 0.3 1 12 39 50 39 55 0.82

2 10 0.0024 0.15 12.4 5.4 2 23 209 230 208 230 0.97

3 10 0.00043 0.027 14.7 1.2 1 23 256 277 256 277 0.97

4 10 0.0015 0.096 13.0 0.8 1 23 283 305 283 305 0.95

5 10 5.4e-05 0.0034 17.6 0.5 1 23 330 352 330 352 0.97

6 10 7.9e-08 4.9e-06 26.5 0.9 1 23 358 380 358 380 0.99

7 10 0.0029 0.18 12.1 6.5 1 23 386 408 386 408 0.98

8 10 3e-06 0.00019 21.5 0.8 1 23 414 436 414 436 0.98

9 10 2e-05 0.0012 18.9 0.1 1 23 440 462 440 462 0.99

10 10 0.0058 0.36 11.2 0.0 3 23 486 507 484 507 0.95

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	10	1	65	4.1	0.3	1	12	39	50	39	55	0.82
2	10	0.0024	0.15	12.4	5.4	2	23	209	230	208	230	0.97
3	10	0.00043	0.027	14.7	1.2	1	23	256	277	256	277	0.97
4	10	0.0015	0.096	13.0	0.8	1	23	283	305	283	305	0.95
5	10	5.4e-05	0.0034	17.6	0.5	1	23	330	352	330	352	0.97
6	10	7.9e-08	4.9e-06	26.5	0.9	1	23	358	380	358	380	0.99
7	10	0.0029	0.18	12.1	6.5	1	23	386	408	386	408	0.98
8	10	3e-06	0.00019	21.5	0.8	1	23	414	436	414	436	0.98
9	10	2e-05	0.0012	18.9	0.1	1	23	440	462	440	462	0.99
10	10	0.0058	0.36	11.2	0.0	3	23	486	507	484	507	0.95

Sequence Information

Coding Sequence: ATGTCAGGGCACGTTGGAAATAAACCCGAGACAACAACTTCCCACTCGCACGTGGAGGCAGGAAAACAAAGCAATGTTGACCATTTCATAATTGATACGTGTGCGGATGAGCTCTACTACTGTGAAGATTGTGGCAACGACTTTGACAGCATCGAGTCGTATAACCTGGCGCACAGTGGGCCCGACAGCTGTTCAGGCAGTGTTGAGGCCAGGTCCAAGGTGACGGTGCATGCCGTGGAGATTAAAGACGAAATACAGTTCGATGACGACACAATAGACATTGATTCCATTGTCGTTGAGGATGATTTGATTGAGGAACTGGACGAGGCAAGCGAGCCCCAGCTCTGGGATGTGCTGGAAGACGACGAACCGTTGCCAGCGACCGAAGCAGAAGTAGATGAAGCCGAAGCCGAGGCAGTCTCGAATAAATCGGAACGCTACTTCTGCTTCGATTGCCATAGCATATTCGAGACACGTCAGAGCGCCGAGGACCACAGCTGCCCACAGGCCGACGCAAATGGTGAAGCACGCAGCAAGCACAACACCAAGCTGGCCAAAACGCAAACGCCAATGCGACGCAAAGTCACAGCTGCCACAGCGGGAAGCAGCAATAGCACCAGCACCGTTTGCCACATTTGCCAAACGAAATTCAGTTCTCCCAAATGCCTCAAGTTCCACATGCGCATCCACAACAAACGTGCCTCCAAATCCATACAGGATGCGCTGCCCGTCGGCGCACATCAGCAGTACAGCGAATTGGATCAGTTCTATTGCGAAATATGCAACAAGAGCTTCGAGCAAAACCTGTTGACTGTGCACAAGCAGATGCATCAGAGCCAGAAGCAGTTCCTGTGCGGTACTTGTAATCGAAAGTTCGATAATGTGACCAACTATGAGATGCATCTGAAAATTCATGAACGCCATGCGCTGAACAACAACAGCAACGCCAATAAGAAGCCCGCCAATCTAAACAAGGATAAACCAGGATTCGCCTGTCAATACTGCGAGCGCGTCTTCTCGCGGCCCTATGAAAAGGTGAAGCACGAGCGCGTCCACACCGGCGAGAAGCCCTACAGCTGCGAGGTGTGCGGCAAAACATTTCGCGTTTCCTACTCGCTGACGCTCCACCTGCGCACACACACAAACATACGGCCATATGTGTGCACCACCTGCAATAAGCGCTTCAAGTCGCACCAGGTGTACTCGCATCATTTGCGCATTCACAGCTCGGAGCGTCTGTATGTTTGTGATAGCTGCCCGAAGTCCTTTCGCACCTCTGTACAGCTCTACGCGCATAAGAATACGCACACGAAGCCTTACCAGTGCGCCGTCTGCAATCGTCCGTTCGCCTCGTTGTATGCCGTCAAGGCGCACATGTCGACCCACAGAACTGGCGACGCGAAAAGCATCAGCAGTGCGGCCATCAAAAGCCAGCAGATATCCAACAAATATTGGTGCGTTACTTGCGGTGCGGAGTATGCGCGACCCTTTGCTCTGCGTCTGCACATGAAGGCAGCCCATGGCCATCCAGACGATGCGGACACACGACTGGCCAGAGTAGCCGCCACGGACGAGGATGAGATTATTGTTCCAGACACCGAAACGGCGGTGCTCATAGCGGCGGCCAAGGCAGATTCAGCCTATCTAAATGCAGCCGCCAATGATGTAGACGTTATGGGTGCGGTGCCCAAATATGAGGAGTGCATTGAAGTATCCACAGATGCGTTCGATGTGGAGACCTTCCACAACGAAGAGATCATCACCGACTGGCTAAAGTAA
Protein Sequence: MSGHVGNKPETTTSHSHVEAGKQSNVDHFIIDTCADELYYCEDCGNDFDSIESYNLAHSGPDSCSGSVEARSKVTVHAVEIKDEIQFDDDTIDIDSIVVEDDLIEELDEASEPQLWDVLEDDEPLPATEAEVDEAEAEAVSNKSERYFCFDCHSIFETRQSAEDHSCPQADANGEARSKHNTKLAKTQTPMRRKVTAATAGSSNSTSTVCHICQTKFSSPKCLKFHMRIHNKRASKSIQDALPVGAHQQYSELDQFYCEICNKSFEQNLLTVHKQMHQSQKQFLCGTCNRKFDNVTNYEMHLKIHERHALNNNSNANKKPANLNKDKPGFACQYCERVFSRPYEKVKHERVHTGEKPYSCEVCGKTFRVSYSLTLHLRTHTNIRPYVCTTCNKRFKSHQVYSHHLRIHSSERLYVCDSCPKSFRTSVQLYAHKNTHTKPYQCAVCNRPFASLYAVKAHMSTHRTGDAKSISSAAIKSQQISNKYWCVTCGAEYARPFALRLHMKAAHGHPDDADTRLARVAATDEDEIIVPDTETAVLIAAAKADSAYLNAAANDVDVMGAVPKYEECIEVSTDAFDVETFHNEEIITDWLK

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00561189;
90% Identity: iTF_00526739;
80% Identity: -