Dlit013985.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Drosophila littoralis
Gene Symbol
-
Assembly
GCA_018903485.1
Location
JAEIGF010000592.1:8523253-8527876[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 25 0.004 0.25 11.7 2.7 1 23 224 246 224 246 0.97
2 25 0.042 2.6 8.5 2.0 1 23 252 274 252 274 0.97
3 25 3.1 1.9e+02 2.6 2.3 3 20 307 324 305 327 0.93
4 25 0.0064 0.4 11.0 1.6 1 23 404 427 404 427 0.92
5 25 0.25 16 6.0 0.7 1 20 467 486 467 488 0.93
6 25 0.72 45 4.6 2.0 1 23 506 528 506 528 0.98
7 25 0.0091 0.57 10.6 2.5 1 23 605 628 605 628 0.94
8 25 0.0032 0.2 12.0 0.5 1 21 635 655 635 656 0.94
9 25 5.1 3.2e+02 1.9 6.5 1 23 665 688 665 688 0.96
10 25 0.00052 0.033 14.5 0.1 2 23 716 737 715 737 0.97
11 25 3e-05 0.0019 18.4 2.5 1 23 745 767 745 767 0.99
12 25 0.052 3.2 8.2 1.7 1 23 915 938 915 938 0.95
13 25 0.0071 0.45 10.9 2.3 1 22 945 966 945 966 0.95
14 25 0.13 8.1 6.9 0.5 1 23 975 998 975 998 0.91
15 25 1e-05 0.00064 19.8 1.9 1 23 1023 1045 1023 1045 0.97
16 25 0.00013 0.0082 16.4 0.9 1 23 1052 1074 1052 1074 0.98
17 25 0.025 1.5 9.2 0.0 2 21 1101 1120 1100 1121 0.94
18 25 0.037 2.3 8.6 4.0 1 23 1166 1189 1166 1189 0.96
19 25 1.2 73 3.9 0.5 1 23 1226 1249 1226 1249 0.93
20 25 0.0037 0.23 11.8 1.4 1 23 1274 1297 1274 1297 0.97
21 25 1.3e-05 0.0008 19.5 0.1 2 23 1321 1342 1320 1342 0.95
22 25 4.4e-05 0.0027 17.9 2.9 1 23 1348 1370 1348 1370 0.99
23 25 2.1e-06 0.00013 22.0 2.0 1 23 1376 1398 1376 1398 0.97
24 25 5.5e-08 3.4e-06 27.0 2.4 1 23 1404 1426 1404 1426 0.99
25 25 0.0035 0.22 11.9 0.9 1 21 1432 1452 1432 1456 0.91

Sequence Information

Coding Sequence
ATGTTGCCGACGGATATTTGTCGCACATGCGCGCTACAGGATGACAGCTTGCTCCCGCTAGCAACGCGCACTAATAAATATGCAAATAAAAGCTTTAGCGACATATTGCACGAATTGACGCAGAATGATCCCTTGCAGGAACATACGGATGATGCCCTGCCGCAGTATTTGTGTGCCGAATGCCTGCACAAGCTTGAAGCTGCCTATGCTTTTGTGTTGCAGGCGCGGCAGGCGCAGGAGCAGCTGTTGCTGCAGCTGCGCAAAGGTTCGCAAAGTCAGTGCTTGGAGGAGATGCCCATAGACATCAGCATGCAGGACATTAAAAACGAAACGGACGTTGACTTAGATTCGGAGCCAAACAGAAAAACCAAAAGCGAGTCGCTACTGGAAGATGCAGGAGAGGTTGAAGAACCAGAGATTGCTGCAGTGTCTGGTCCAGCCTTAAAATGGCAGCCGGAAAGCGATAGCGACAATACTAAGGCGTCTTTTGACCAGCAGGACATGGACTTAAAGCCCAAGCAATTGCGGCGCAGCCTACGGAAAGCCAATCATGGCATAGTCAGCGAAAATGAAGCCTCCTTTGCTAATATGAAGACCTTGACTGTGAAGCGTCGCCGCGGACGTCCCGCGCGTCATCCCAAAAAAAGAAACATCAACGAGGAGGGCCGACATACGTGCCAGGTGTGCGGGAAGACATTTTCGTGGCACCGCGACATGGTACGCCATGCCCGCATACACTTCGAGCAGGCGGCCTTCGTGTGCGACAGCTGCGGCAAGAGTTTTTTGCGCAAGGACAAGTATATGTTTCATCTGCGTTCGCACGAGAAGCGTGCAGCCAAATGGCAGGCATTGCAGCTGAGTAGTGAATGGCGCTTTGCGGAGCGCCTATACAGCTCGGGCCGGCTCAAGCATGTGATCTGCAAGCTGTGCGGCTTGAAGTGCCAGCGCATTCAGGAATTACGCGATCATTTGGCGTGCCATGTCAGCATTGAAACGTTGTCTAAATTGAGCATGGAGAGTGATGTGGTCAAAGAGCAGTTTGCCAACATGCAGCAGCAATTGGACTTGGTTCAGATCAAGCAACAGGTGTGCGCTGACATTGCCAAGGGACGTGAGCTGCTGGACAACTATTACGCTGTGGTCAATGCGTATGGCTATGAGCTTTGCCTCAGCGACTCGGATGAGGAACTACCTGACTTGACGCCACAGTACCGGTGTCTGCCATGCAACACCACCTTTACGCGCAAATATCGCCTCATGCGCCACACTCTGGAGGAGCACACGCATTCGGAAGCGGATGTACCCTGGCAACGTTGTAATGTTTGTCACATTGGCTTTTTGTGCGCCAAAGTGCTGGAGCAGCATCAACGCACGCAGTGCCACAATAAACTAAAGCGTTATAGCTGCCCCAATTGTCCAGGAAAATTTGTTTGGAAGCAGAATTTGAAGCAGCATGCGTGCTCCCAACGCAACGGGGTACAAAAGGAGCAACAGCCGCAGAAGGTCGCCCATCAATTCCAATGTTGTCTCTGTGATGCCCAACTACACAGCATGGGAGGATTACGCTCTCATTTACTCACCCATCGCGATGGACGCAGCGGCATAGATCCGAAGAAGCGGGCTGCCTTCTTTCGCACCTATTATCCCGATGGCTTTGCCTGCAGCTTGTCAGAGCTGAGCGCACGCATTGCCGGCGACTTTGAGGCAGAGGATTACGGACGGTACTTCAATGCCAGCACTAGCAGTGGGCAGGAGCTGGATTTCTTTGACTCGGAGACAGATGAGGAGCAGTTGAGCTCTGTCGCTGAGCTGCATATATGTTCACTGTGTGGCGAGACCACAATACGCCGGACCCAACTGCTTGAGCATCAGCAGCACCAGCATAGTGAGGCCAGGCTGCCGCATGCCTGCGAGGACTGCGACATGAGCTTTGTAGCCGATTCCTTACTGCAACGGCATCGCCGACATATCTGTGCCAAGCGGCATGCCAAGTATCATTGCCAGTTTTGCAGCCAGCGTTTTTACTGGCACTCCAACTATGAGCAGCATTTGAAGCTGCAGCACGAGAAGGAGGATAAAACAGAGGTTACCGAAGAGCAGGAGACCAGATTAAGAAGCAAGCGCCATCCAACAGCAGCCAAGCTGCAGTGTGGCGAGTGCGAAAAGGTCTTCATCTGGCCCAAGGATCTGACACGTCACAAGCGAATACATCAGCCGCAGGCGTTGGCTCAGTACGAATGCGCTTACTGTGAGCGCAAGTTCCATCGCAAGGATGGCCTGAAGTCGCATTTGCGCGTGCACGGTGAACAGCAGCTGGACGGAACGATTGCCAGTGATCAACCATCGTCCGTTCTGCAACTCATGCCAGTAGTGTTGACCCAACTTTGCCGGCCCAATGGTTGCAAGCAGATTCAGTGCATGATTTGCCTTTCGCAGCACACAAAGATCGCCGATCTGCGTGCGCATTTACTCAACCATCAGTTTGCGGTGATGTTTGCGGAGGATCGTGGTAAGTCGGAGAACATTGCAAATATTTCACGGGCTCTATATCCAGAGCTAGCCACGCCGCTGGATCAGCAACAGCTGATCGGGCGCATTCAAAGCGATGTGGCCAAGGGCCTTGAACTGGAAAGATTCATATCCATTACCAACGAGGCGGGCATAGAGCTCAGCTTGGACAGCAGCGAGACTGAAACAGATTCTGACTCTGCCGAGGCAGTTGGAAGCAGAAGCGGGCGTATCTACAGCTGTGAGCTGTGCCAGCTGAAGGTGCAGCGCAAGCATCAGCTCTACGCCCATCAGCTGGAGCAGCATACGTGGCAGCAGGCGACGCATATTTGCACCCATTGCCAGGCCAGATTTGTGAATGAGCAGCTGCTGGAGCATCATTATCGCACGGTCTGCCGAAACGCGCAGCGGCGTTTTCTATGTCGCAAATGCCCATTGCGCTTTCGCTGGCGCGAGAATCTGAAGCTGCACACGGACGTAGCGCACCAAGAGGCAAGTGAAGAGCATTTGAACTTGGGCATTCAATTGAACGGCACACATCTGCTGCCTATTGTTAGCTATGACTGCACCGAATGCAATCGCAGCTTTAAAATGCAAAAGGATCTCACCAGGCACACCCTGATGCATGCCCAAGAGTCGAGCATTTACCGTTGTCGCTGGTGTGCACGGCGTTTCTATCGCCAGGCCAATCTTCTGCAGCATATCGAGCGTCATGGCATTAGCGCCGAGCAGCTGCCTTATGCGGAGGCACTGCTCAATGCCAGCCGACATCCGCATGGCAAGAAGTGCATCCAGTGCAAGGTGTGTAATATAGCCTACCCCACTATTGCCGCACTGCGCGCCCATCTGCAATCTGCGCCAGGAGGCACACATCATGAGCTTGACTCGATGCTCAACTACTCTATAACCAATCAGCTGGGATATGAGCTGCAGCTGGACGACTCGGAAACAGATGAAGAGGCCAAGCCGTCGGGCACACCCACACATTACACCTGCGGTATGTGCCAACTACGCTGTGTGCGCAAGTTTGAGTTGCATCAGCATCAGCAGGCCATGCATCGACTGGAGCGCATAAGCGAGGGTTGCGAATTTTGCATATTTAAGAGCGTCTCTCCTGATCTTATTAACTATCATCGTCGTGCGCTGTGTGACAACACAGAGAAAAAGTTCAAATGCATCAAGTGCGGCTACAAGTTTATGTGGGAGGCGAATCTGCTGCAGCACGTGAAGCTGCAGCACCCCAGTAGCGATCTGCAGCAGCAAGTGATTTCCATGCGCGCAACGGAAACTTCGAGTACTGAGTGCCAGATCTTTCAGTGCGGTCAGTGTCCTAGTAAATACAATCGCAAGGATCGTCTGACAGCACACGTAAAAAAATATCATTCAGCAGAAACTAGCTCCAAGGGTGCCCCAACAAAGACTGCAACAGGCGCCAAGCAGCAGAAAAGTTTTCTCTGTGCCTTTTGCGGCAAGGCGGTTAGTTCCTCATCCAATCTGATCATACACATACGTCGGCATACCGGCGAGAAGCCTTTCAAGTGCGACTACTGCGACATGGCGTTTCCACGGTCGTCCGATCTGCAGTGCCATCGACGCACCCATACGGGCGAGCGGCCGCATGTCTGCACCGTTTGTCAGAAGGGCTTCGCGCGCTCCTACAAGCTGCAGCAGCACATGCGCATCCACAATGGCGAACGCCCCTACAAGTGTACTTATTGTGATAAGAGCTTCACGCAGTCGAATGACCTGACGCTGCACATACGGCGGCACACGGGCGAGCGTCCCTATCATTGCAACACGTGCGGCGAGCGTTTTATTCAGGGCACAGCGCTCAAGAATCATCGACTACAGAATGGACACTACGAGACGGAAGCAGACCAAGTAAAAGATGTCTAA
Protein Sequence
MLPTDICRTCALQDDSLLPLATRTNKYANKSFSDILHELTQNDPLQEHTDDALPQYLCAECLHKLEAAYAFVLQARQAQEQLLLQLRKGSQSQCLEEMPIDISMQDIKNETDVDLDSEPNRKTKSESLLEDAGEVEEPEIAAVSGPALKWQPESDSDNTKASFDQQDMDLKPKQLRRSLRKANHGIVSENEASFANMKTLTVKRRRGRPARHPKKRNINEEGRHTCQVCGKTFSWHRDMVRHARIHFEQAAFVCDSCGKSFLRKDKYMFHLRSHEKRAAKWQALQLSSEWRFAERLYSSGRLKHVICKLCGLKCQRIQELRDHLACHVSIETLSKLSMESDVVKEQFANMQQQLDLVQIKQQVCADIAKGRELLDNYYAVVNAYGYELCLSDSDEELPDLTPQYRCLPCNTTFTRKYRLMRHTLEEHTHSEADVPWQRCNVCHIGFLCAKVLEQHQRTQCHNKLKRYSCPNCPGKFVWKQNLKQHACSQRNGVQKEQQPQKVAHQFQCCLCDAQLHSMGGLRSHLLTHRDGRSGIDPKKRAAFFRTYYPDGFACSLSELSARIAGDFEAEDYGRYFNASTSSGQELDFFDSETDEEQLSSVAELHICSLCGETTIRRTQLLEHQQHQHSEARLPHACEDCDMSFVADSLLQRHRRHICAKRHAKYHCQFCSQRFYWHSNYEQHLKLQHEKEDKTEVTEEQETRLRSKRHPTAAKLQCGECEKVFIWPKDLTRHKRIHQPQALAQYECAYCERKFHRKDGLKSHLRVHGEQQLDGTIASDQPSSVLQLMPVVLTQLCRPNGCKQIQCMICLSQHTKIADLRAHLLNHQFAVMFAEDRGKSENIANISRALYPELATPLDQQQLIGRIQSDVAKGLELERFISITNEAGIELSLDSSETETDSDSAEAVGSRSGRIYSCELCQLKVQRKHQLYAHQLEQHTWQQATHICTHCQARFVNEQLLEHHYRTVCRNAQRRFLCRKCPLRFRWRENLKLHTDVAHQEASEEHLNLGIQLNGTHLLPIVSYDCTECNRSFKMQKDLTRHTLMHAQESSIYRCRWCARRFYRQANLLQHIERHGISAEQLPYAEALLNASRHPHGKKCIQCKVCNIAYPTIAALRAHLQSAPGGTHHELDSMLNYSITNQLGYELQLDDSETDEEAKPSGTPTHYTCGMCQLRCVRKFELHQHQQAMHRLERISEGCEFCIFKSVSPDLINYHRRALCDNTEKKFKCIKCGYKFMWEANLLQHVKLQHPSSDLQQQVISMRATETSSTECQIFQCGQCPSKYNRKDRLTAHVKKYHSAETSSKGAPTKTATGAKQQKSFLCAFCGKAVSSSSNLIIHIRRHTGEKPFKCDYCDMAFPRSSDLQCHRRTHTGERPHVCTVCQKGFARSYKLQQHMRIHNGERPYKCTYCDKSFTQSNDLTLHIRRHTGERPYHCNTCGERFIQGTALKNHRLQNGHYETEADQVKDV

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00563306;
90% Identity
iTF_00551040;
80% Identity
-