Basic Information

Insect: Drosophila limbata
Gene Symbol: -
Assembly: GCA_963924055.1
Location: OZ001354.1:16714094-16718375[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 7 0.17 17 6.7 0.0 2 23 196 218 195 218 0.93

2 7 1.7e-06 0.00017 22.5 2.8 1 23 905 927 905 927 0.98

3 7 0.00079 0.08 14.0 3.6 1 21 960 980 960 981 0.94

4 7 3.7e-06 0.00037 21.4 2.5 2 23 988 1009 988 1009 0.98

5 7 0.046 4.6 8.5 2.5 1 23 1015 1037 1015 1037 0.98

6 7 0.029 3 9.1 0.7 1 23 1043 1066 1043 1066 0.96

7 7 0.0011 0.11 13.6 0.3 1 23 1076 1098 1076 1098 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	7	0.17	17	6.7	0.0	2	23	196	218	195	218	0.93
2	7	1.7e-06	0.00017	22.5	2.8	1	23	905	927	905	927	0.98
3	7	0.00079	0.08	14.0	3.6	1	21	960	980	960	981	0.94
4	7	3.7e-06	0.00037	21.4	2.5	2	23	988	1009	988	1009	0.98
5	7	0.046	4.6	8.5	2.5	1	23	1015	1037	1015	1037	0.98
6	7	0.029	3	9.1	0.7	1	23	1043	1066	1043	1066	0.96
7	7	0.0011	0.11	13.6	0.3	1	23	1076	1098	1076	1098	0.98

Sequence Information

Coding Sequence: ATGCATTACAACATGAACGACGCGGATGTGGCGTTCTCGAGCTTCTACAGCACCGTGGGCAACCAGctgcAGCTTCACAATGCCGATCTCTCGCTGTCCACGCCGATACACTCCCTGGATCACGACAATTTCACCGGTTTATTTGACGACGACCAAGCTCTGTTAAATATTCcaataacaacgacagcagcgaCATCATCTTCGCACAAAGGGAACGCGGGAGGAGTTGCCGAGACTACGTGCATACCCTTTGTGCAGATCCACACGACAGACCTGCAGCAACAGTCGGAGCCGGGCCGAAGTTATCGCAATGGATTCCGACGGAAGACAGCCGAAATCAAATCGGAGGCGGAGCTCATCAAATCCGAGCTGGCCGAGGCGGCGGCCAAGGAACGCAtcaatgccacgcccacgcctCCCACATCCAAGGCGATATCGATAGGCGGCGATGTCTGtgcagacacagacacagtgCTGGCGACACCTCTCAACAAGTGTCCCAACTGTCCGTTCCTCAGCCTGTGCCAGGTGCGGACACAAACCCACATCAGCGGCTGTTTTGGCCTCGATGCGCAGAGACGCATCCAGTGTCCAGGCTGTGCGAATGTATTCTACAACTTGGACGTGCTCAATCTGCATCTCAGTGAGGATCATGAGCTGGAGCCTCAGGAGATATCCACGCTGCTTCAGTCGCTGAAGTTAACTGGCCAGCCCAATGAGACGACCGCCAAGAAGACGCAACTGGCGCCCACGAAGAGTCGCATCTTCATCAAGAATGTCGACTGTCTGCGGGAGCCGTTACGGGAACAGGATGtcaaccagttgtccgattttctGCCACTCTTGTCATCGCCGCCAGATGGCAGCGCTGGGAATATACTCGACCTGCTGGATGACGTTGCTGATGTGGAGGCAGTgaatcagcaacagcaactgcatcaaccacaacagcatcagcaactacaacaagatACAACGATAAATGTCCAAAAGCCACCAGGTCAAAAGATATCCATCAAGAGCGTCGATGTGCTGAGGGAGCCAGCATTGTTGCCCTTTGACTTTCAGCTGCCCAGCGCTGTggatcaacagcagcagcagcaacagttgtcGCAGCTGCCACAGTTGCCCACGCTGATGATGCCCAACAATATGCTGGACGTGGAGCCGGAGAAGCCACGTCAGCCCAAGATCTACATACGCAATGTGGACATTTTAAAGGAGCCCATGCTGTTGCCTGGCATGGGATTCAATGGAATCGCCGCTTCCAGTGTCGCCAGTCCCGTGGAGATATTTCCCGCCGAAACGCTGCTAACGCCAACGGGTCCAGTTGGTCCGTTGCCTGGATTCGAGCCCGCTCTGGCGCCGCTGGCCAACATGTGCGCCGAGGCATTCAACTTTGAGTCCGTGCTCAGCGGTGCAGGCACCGCCAGcagcgtcagcagcagcaacaactttagCGCCCTCGACCTCGACTTTGGTGTGGACTTTGAGCACAGTGTGCCGCTGGTAACGGAGCCAACGCCACCGCCAGGACCAgcgccaccgccaccaccaccaccgccgcTGCCTGCACCGCCAATGGCCAGCGGCGAGCAACTGACTGATTTGAGCATAATACAACAGGATGAGCTCAACAGCTACTTGCCAGTGAATGCTCATCCAACactaacagcaacaacaacaacaacagcggcagcgTCGACAACATCCAAGCAAAAGATCTTTATCAAGAACGTGGATATATTGAAGGCACCACAACGTGGCACGTTGCATCTGCGCACTGTGGACGAGCTCAATCTGATGAATCGCAACGAGGTGGAGCACCTTATTGTGCCCAACCGAGAGCCGTTGCCCCTGGAGCTGCCGCTGAGTGCGCCGGCAACAACACTGGAGTCCTCCCTGGTCGACTTCCATCAGCAGCCACAGGGATCGGCGCCTTCCTTGAGCTACGATGACAGCTACGATTTGGCCGAGGATCTGGAGTGTTGGCCCTGGATGGAGGAGGCGGCGACAGTTGGAGTTGCACCGGAGCAGGAAACGGGAAACAGCTCGCAGCTGGAGTTGCCGCACAATGCCGAGGATATACTCATCAAGGATTTCCCCCAGTTGTACGCGTCGCAGACGCCAGACGTGGCCACCGTGCCACCTCCACCTCTGGTGCCCGTCACAGCCTCTCCAGCGACGACTGCGAGTGCCACAGCCACTGACAATCTGAGTGGTCCGCCAGTGCCGCCACTGGTGCCGTTGGCAGCCGAAGCTCCGGCCGAGAAACCCGCTCGCATCTATGTGGCCAACAACCTGTTGCCCGCCGCCGTTGAGCCACCGCTGCCGGGTGGCACCTCCGTGCGTGGTCGTCCCTACGGTGCCAAGCAGGCGGGTCAGGCCAAGCGACGTCCGGCACAGGGAGCTGCCCAGACGCTGGAGGGTGGCAAGTGCACTGTGGAGGGTTGTATGTTCCGGTTCAAGTCGCCGACGACTCTGGAGTACCATGGACGTTGTCACAACGGAGCTCTGGGCTCGGCACAGCCGATGATCTGTCCGGAGTGCAGATCGACGCAGTTCAGCAACTGGAATTGCCTGCACACGCATCTCTGGCGCACACATGAGATCGATATGGAGCTGTACTGCTGTCAATTGTGCAGTTTTAAGACGCCCATCTACTCGCGGCTGGTCAACACCCACGCCAAGATCCATTCCGAGGAGCGCAATTACAAGTGCGAGCAGTGCGGCAAGGGATTCAAGAACACCAAACAGCTAAAGAACCATCGGCGACTCCATCGCACTCAGGGGCTGGGCATGGCCAAGTCCAGTGGAGCGGAGGAGCAGGCAACAACTCCGACTCCCACTCACACTCCGCACACAACTCCGACGTTGCATCGTTGCGAGGATTGTGGTGCCGCCTTCAAGCATCGGAAAACGTTGCGCGAACATCTCTGCAAGCAGCGCAACGAGCAGCCCCAGTGCACCAGTTGCCAGCGCGTCTTCAGCTCGAAGAGCAGTCTCAAGCTGCACATGCGCAGTCACCAGACCAACAAGCGCTTCAAGTGCGAGAAGTGCGAGTTTGAGGCAAACGATCACAATTCCTTTCGACGTCATCTTGCCACACATCGGGATCCCAAACGCTATGCGTGTCCACACTGCGACTTCAAAGCCATACAGAGCACTGCGTATCGGATACATCTAGAGAAGCGGCATCCGGAGCAGGAGCTGTCCACtattatatacaaatgtaACGTGTGCAATTTTTCCAGCATCAATCGTGGCCTGCTGCTGGTCCATCAGGCCAAACATGAACCAGCTCCAGTTGAATCTTCAAAGATCAAGGTGAAGAGCAGCCTGCTGCTCGCACATTCCAAGGAACAGGATAAAGTGGCTTTTCTGCCGCCAGACAGCGCTCTGAATGCCTAG
Protein Sequence: MHYNMNDADVAFSSFYSTVGNQLQLHNADLSLSTPIHSLDHDNFTGLFDDDQALLNIPITTTAATSSSHKGNAGGVAETTCIPFVQIHTTDLQQQSEPGRSYRNGFRRKTAEIKSEAELIKSELAEAAAKERINATPTPPTSKAISIGGDVCADTDTVLATPLNKCPNCPFLSLCQVRTQTHISGCFGLDAQRRIQCPGCANVFYNLDVLNLHLSEDHELEPQEISTLLQSLKLTGQPNETTAKKTQLAPTKSRIFIKNVDCLREPLREQDVNQLSDFLPLLSSPPDGSAGNILDLLDDVADVEAVNQQQQLHQPQQHQQLQQDTTINVQKPPGQKISIKSVDVLREPALLPFDFQLPSAVDQQQQQQQLSQLPQLPTLMMPNNMLDVEPEKPRQPKIYIRNVDILKEPMLLPGMGFNGIAASSVASPVEIFPAETLLTPTGPVGPLPGFEPALAPLANMCAEAFNFESVLSGAGTASSVSSSNNFSALDLDFGVDFEHSVPLVTEPTPPPGPAPPPPPPPPLPAPPMASGEQLTDLSIIQQDELNSYLPVNAHPTLTATTTTTAAASTTSKQKIFIKNVDILKAPQRGTLHLRTVDELNLMNRNEVEHLIVPNREPLPLELPLSAPATTLESSLVDFHQQPQGSAPSLSYDDSYDLAEDLECWPWMEEAATVGVAPEQETGNSSQLELPHNAEDILIKDFPQLYASQTPDVATVPPPPLVPVTASPATTASATATDNLSGPPVPPLVPLAAEAPAEKPARIYVANNLLPAAVEPPLPGGTSVRGRPYGAKQAGQAKRRPAQGAAQTLEGGKCTVEGCMFRFKSPTTLEYHGRCHNGALGSAQPMICPECRSTQFSNWNCLHTHLWRTHEIDMELYCCQLCSFKTPIYSRLVNTHAKIHSEERNYKCEQCGKGFKNTKQLKNHRRLHRTQGLGMAKSSGAEEQATTPTPTHTPHTTPTLHRCEDCGAAFKHRKTLREHLCKQRNEQPQCTSCQRVFSSKSSLKLHMRSHQTNKRFKCEKCEFEANDHNSFRRHLATHRDPKRYACPHCDFKAIQSTAYRIHLEKRHPEQELSTIIYKCNVCNFSSINRGLLLVHQAKHEPAPVESSKIKVKSSLLLAHSKEQDKVAFLPPDSALNA

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00523289;
90% Identity: iTF_00602172;
80% Identity: -