Basic Information

Insect: Drosophila limbata
Gene Symbol: T
Assembly: GCA_963924055.1
Location: OZ001353.1:13101831-13104205[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 5 0.0014 0.14 13.3 4.1 1 23 556 578 556 578 0.99

2 5 3.4e-06 0.00034 21.5 0.2 2 23 607 628 606 628 0.98

3 5 1.1e-05 0.0011 19.9 0.4 1 23 634 656 634 656 0.99

4 5 7.7e-05 0.0078 17.2 3.0 1 23 662 685 662 685 0.97

5 5 2.3e-06 0.00023 22.0 1.2 1 23 691 713 691 713 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	5	0.0014	0.14	13.3	4.1	1	23	556	578	556	578	0.99
2	5	3.4e-06	0.00034	21.5	0.2	2	23	607	628	606	628	0.98
3	5	1.1e-05	0.0011	19.9	0.4	1	23	634	656	634	656	0.99
4	5	7.7e-05	0.0078	17.2	3.0	1	23	662	685	662	685	0.97
5	5	2.3e-06	0.00023	22.0	1.2	1	23	691	713	691	713	0.98

Sequence Information

Coding Sequence: ATGCAGACACTAAGCGATTCACTAAGGTCCATATTTACTGAATCGCAGGTCCGAAAATTGCAGAATGGTGGCAAAAGAATCAAATGGAATCAAGATGACATGTCGTATGCGAGTTGTCTCCACGCTGCTGGACCCCGGGCATATCgtcatttgtttaaaaaaggCTTTCCACTACCGTGCCAATCCACCCTGGAAAAATGGCTGCACTCAATAGAAGTAAAACCCGGTATCTTGGAACTTGTAATCGACTTAATGGAGAAAGCCGTCAACATTGACGAGAAGgacaaaatatgtattttgagTTTCGACGAAATGAGGATAACCTCAAGCTGCGAAAATGATTCATCTCAGGGAGGAGTACAGCAGCCACGGGACTATGTCCAGGTCACAATGGCTCAAGGATTGCGCAAGTCGTGGAAGCAACcaatatattttgactttgACAAGGCAATGAGTGTCCCCACACTGCACATGCTGATCCAAAAGCTGTATACGATAGGCTACTATGTTGTCGGCATAGTTTCCGATATGTGTCCCACTAACCTGAGATTGTGGACAAATCTTGGAGTTTCGCATGagAAAACGTGGTTTAAGCACCCATCTGACTCCGATATGAAAGTTTTCGTATTTGCAGATGCAGCTCATCTCTTGAAGCTAATTAGAAATCACTTTCTTGATTCTGGACTTGTTGTTGGTGACAAACTCATAACTCAACAAACCGTAAGGCAAGTGATGAGTCACGCTTCTTTATCAGATATTTCCAATATGTGGAAAGTTAATGAAGACCATCTAAACGTTCGATATGCAGGCCGGCAAAAAATCAAGCTGGCAACTCAATTGCTTTCAAATAGCACAGCCAGTGCAATTAGACGTTGCCAAACACTGGGCATTGAAATAGACAACGCATCTGAAACAGCGGATTTTATTCAGTTATCAAATGATTGGtttgacatttttaatgtaaagCTGCCAGCTTCTAAGAGTATTCCCACCAAGCAACCATTTGGCCAAAGTATTGATGCACAGCGTAAGGTGTTAGATGAGATGACTGCACTAATGtcgaaaataataataccaaATGGTAAAAAGTGTTGGCCGTTCCAAAAAGGAATGATTATAAGCAACACTTCGTTATATCTTTTGCACCAATATGCTGCGAAAAGATATAGCGTGGATCATTTAATCACTGGACGATTATCGCTGGATCAATTGGATCAGTTCTTCGATGTAATATGGGAAAAAAATGATCTGCACGATCATCCAACTGCATCAGAAATCAAGTTGCGGTTGCGGAAATATTTATTGGGAAACAGTTGTTTAAGGCTGGATGTGACAGAAGAAGACATAGACATAAAGATAGAACAAAAGGAATTGACGACTACGAACGAGGACAAGGAAAAGGAATGCTACCCAGAAAGTCCTGAGGATTACACGTCTAGTAGTAGTTGCAGGGACCAAGATGAGCTGGCTGATGTGAGTGTTCAGTCTGAATTGCTTGGGACAGAAGCTTGGGAACTGTCGGAAGGAAATTTAGAAATCAAGATCGAGGAGAATGAACTTGTGCCTATTGAAAGTGAGCACAATGTGTCAAGTTCTGAAATACAAAACCACGAATCCAAGCTGTTTTCCAACTTACAGGTTGAAAATGTTGCACAAAAAAATCGATTCCAATGTCCACAATGCTCAAAGATCTCTGAGAAATGCTCGCACTTCGATGCGCACATTCGTACTCACACTTCTGAACAATGCCCTAAAGAATTCGCTCTACAAACGGGTCCGCAATTCCACCTCTCGACTCATCCAGGCGAACAAATCAACAAGTGTCCACACTGCGGACAGTATTTTATAGACAGCGACGAGCTCGTTGAGCACATACGTATTCACACGGGAGAACGAACTTATTCTTGTACAGAGTGCTCCAAGGAGTTTGGCTATGCGTGGCAATTGGAGACACATATTCGAAAGCACACCGGAGAGCAACCATTCAAATGTCCCCACTGTCCACAGACCTGTAAGAACATAAAGGATCTAATCAAGCATATCGAATCTTCTCACTCTAGACAACGTCTGCACAAATGTCCACAGTGTCCAAAGGCTTTCATCAGCGTTTCCAATTTTAAAGAGCACATCAAAAGTCATTGCATAAAAAGTCCATAG
Protein Sequence: MQTLSDSLRSIFTESQVRKLQNGGKRIKWNQDDMSYASCLHAAGPRAYRHLFKKGFPLPCQSTLEKWLHSIEVKPGILELVIDLMEKAVNIDEKDKICILSFDEMRITSSCENDSSQGGVQQPRDYVQVTMAQGLRKSWKQPIYFDFDKAMSVPTLHMLIQKLYTIGYYVVGIVSDMCPTNLRLWTNLGVSHEKTWFKHPSDSDMKVFVFADAAHLLKLIRNHFLDSGLVVGDKLITQQTVRQVMSHASLSDISNMWKVNEDHLNVRYAGRQKIKLATQLLSNSTASAIRRCQTLGIEIDNASETADFIQLSNDWFDIFNVKLPASKSIPTKQPFGQSIDAQRKVLDEMTALMSKIIIPNGKKCWPFQKGMIISNTSLYLLHQYAAKRYSVDHLITGRLSLDQLDQFFDVIWEKNDLHDHPTASEIKLRLRKYLLGNSCLRLDVTEEDIDIKIEQKELTTTNEDKEKECYPESPEDYTSSSSCRDQDELADVSVQSELLGTEAWELSEGNLEIKIEENELVPIESEHNVSSSEIQNHESKLFSNLQVENVAQKNRFQCPQCSKISEKCSHFDAHIRTHTSEQCPKEFALQTGPQFHLSTHPGEQINKCPHCGQYFIDSDELVEHIRIHTGERTYSCTECSKEFGYAWQLETHIRKHTGEQPFKCPHCPQTCKNIKDLIKHIESSHSRQRLHKCPQCPKAFISVSNFKEHIKSHCIKSP

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: -
90% Identity: -
80% Identity: -