Basic Information

Insect: Drosophila limbata
Gene Symbol: ken1
Assembly: GCA_963924055.1
Location: OZ001354.1:4231229-4233682[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 12 0.073 7.4 7.9 5.9 3 23 269 289 267 289 0.96

2 12 0.00098 0.099 13.7 0.5 1 23 295 320 295 320 0.94

3 12 0.0021 0.21 12.7 1.2 1 23 327 352 327 352 0.93

4 12 0.0018 0.18 12.9 4.1 1 23 362 384 362 384 0.96

5 12 0.002 0.21 12.7 2.2 1 23 391 413 391 413 0.97

6 12 0.0079 0.8 10.9 0.5 1 23 419 441 419 441 0.97

7 12 0.058 5.8 8.2 2.6 1 23 447 470 447 470 0.97

8 12 0.021 2.1 9.6 4.1 1 23 476 498 476 498 0.95

9 12 0.023 2.4 9.4 2.6 2 23 505 526 504 526 0.95

10 12 0.0002 0.02 15.9 0.8 1 23 620 643 620 643 0.95

11 12 0.00041 0.041 15.0 0.8 1 23 649 671 649 671 0.95

12 12 1.1e-05 0.0011 19.9 2.3 1 23 677 699 677 699 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	12	0.073	7.4	7.9	5.9	3	23	269	289	267	289	0.96
2	12	0.00098	0.099	13.7	0.5	1	23	295	320	295	320	0.94
3	12	0.0021	0.21	12.7	1.2	1	23	327	352	327	352	0.93
4	12	0.0018	0.18	12.9	4.1	1	23	362	384	362	384	0.96
5	12	0.002	0.21	12.7	2.2	1	23	391	413	391	413	0.97
6	12	0.0079	0.8	10.9	0.5	1	23	419	441	419	441	0.97
7	12	0.058	5.8	8.2	2.6	1	23	447	470	447	470	0.97
8	12	0.021	2.1	9.6	4.1	1	23	476	498	476	498	0.95
9	12	0.023	2.4	9.4	2.6	2	23	505	526	504	526	0.95
10	12	0.0002	0.02	15.9	0.8	1	23	620	643	620	643	0.95
11	12	0.00041	0.041	15.0	0.8	1	23	649	671	649	671	0.95
12	12	1.1e-05	0.0011	19.9	2.3	1	23	677	699	677	699	0.98

Sequence Information

Coding Sequence: ATGAATGAGGGGAGTGAATACTCCATACACTCGATATGCCGCATTTGCTTGAACCACCTGCGCAACGATGCGGTGTACGATCTGTTTCTGGTCCCGGGCCTGGCCAAAAAATTATGTGTGTGCACTTCACTCTCTGTGGAACAGCACGACGGATTCCCCAAGAATCTGTGCACCCAGTGCTATACGAAGCTGGAGGACTTGCATGGCTTTCAGAAGATGTGCGTGGATTCGGTGCAAAAGTTTCAGGATATGGTGGCCAATAATTATTTTACGCCCGTCATTTCGGATATCAATCAAATTGACAATGTTGATGTGCTGAATATTGCGCCACCTGAGGGCGAAATGGAAGAAGATCGCATTAACTTTGATCCATTGCTGAATACGAAAATCGAGGTAATCGAGAATGAAGATGATGTCTTTAAAATGCTTGAAGATGTCGACAAGGATGTCGAGGATGTGGACAAGGAGGAGGAATCATCGTCGGAGAGCGAAGAGgaaaatgataatgatgatggcgacggagatggagatggtGATTTTGAGGTGAACAGCAGTGAGTCTGATGATGCCATGCCATTGTCACGTTTGCGCGGCTCAACCAGAGCAAGAGCATCCAAAGCCAAGGCCAGAAAGAAGACCAAGCGCAATAATGATAACGATGATGACAATTCCTCCAGCTCTGAATcgaatgatgatgatgatgacgatgacaatgatgatgatgacgatgatgctAGACCCAGATCGAAGCCAAAACGCAAACGTATTCCGGCTGGTGAACGGGATCGTCATAAACTCATCGATTGCCACATTTGCCATCAGAAGTTCAAGAAGGCCATACGCTACGAGGAGCATATGAAGCATCACAATGATCTGTTGCCATTCCAGTGCACGGTGGAGAGCTGCAAGAAGGGTTTCACCACCGCCGGCGGTCTGCGTCTGCACATGGATCATGCCCACATCGAATTCTCCGAGGTGCATGCCTGCACCTTTGAGGGATGCGACAAGACATTCCCCCGCTCCGTCTTGCTCACGTTCCACATGAAGAAGGTGCACAAGGTGGCCAAACCGGATGTTAAAAAGCACGCCTGCACCGAATGTGAGAAGGTATTCCGCTGTCCAACCGCACTCAAGAAGCACATGTATAAACACACGGGTGAGGAGCTGCCATTTGCCTGTGAGATCTGCGGCAAGCGATTCCACATCCACAGCGTGCTCCGGGATCATCTGCTGCGTCATGCCGGCGTCAAGAATCACGTGTGTCCGTACTGTGGTGTGGGCAAGACCACCAGGCAGGAGTGGAACAAACACATCTTGACGCACACCCGGGAGAAGCAGTTCCAGTGCCGACAATGCGATCATGCCTCCCACAACAAGCAGGCGCTGTCCAATCACGTCAAGGTCGTCCACATGAAGATCAAGAACTTTGCCTGCCAATACTGTGGCAAGACATTTGGCAAGTCCCATGCCTGCAAGATCCACGAGAGACTGCACACGGGCGAGAACTGCTGCGAGTGCAAGATCTGTGGCAAGATCTTCCTCTTCGAGAAGAGATTGACCAAGCACTTGCAGTTGCATGAGAAGCGTGATATACCGCCAGCTGCGACCGCTGTGAAGCCCCAAGATGACGGACAACAGAGCACTCCGAGTGGGAGTCAGCAGGATCCTCAGAGTCATATGACAACAGAGCCGGTGGACGTGAAGCCACTGCCAGTTGTTCCCCCCAAGCCGAAGAATTCCCATCGAGTGGAGCGTGTGGACATTTCCCAATTGGCTGGCACCTCGGTTAATCCAATATCATCTGTATCCGTGCCCTCCTGGTCGCCACAGGTCAACTTCACCAAGAAGGAAGGCCAGCACATTTGTCCAGGCTGTGGACGTGGCTTCAACCACATTGGCAACATGAAGCTCCACTACAAGATTATACACGAGAAGGTCAAGGATTTCGCGTGTCGCTATTGTCCCAAGCGGTTTGCCAAGGCGCAATATCTGCGCAATCATGAGTATATACACACTGGTGAGAAGCCCTTCGAGTGCAAGATCTGTGGCAAACATTTCCGTCAGGAGCAGGTGCTAAAGACGCATCTCAAGGTGCACGACAAGCCGCCAAAGCAGCCCAAGGAGAAGAAGCCCCCGAAGCCGTCAGTTAGCAAAGCCCGTGGATTAAAAGTTGAGctcaacaaaaaacaaccaaaGATTCATGACGAATATCAGGATCCGGCTGCGGAACGtgcggcagcaacagccgcACTCCTGGCTCAACAGATCGAGGAGAATGAGGCGAAGCGGAAGCAGGAGGAGGCAAATCGCAAGATTCAGGAGGCCGCCTGCGAGCAGCTCAATAGACTtcaaaagcaaatacaaaGCGAAAAGGGATCCTACGATAGCTACTATGGACAGAAAGCGGAAGCCGATGGCATCAATCCCGATGTTCTCAAATTAGATCAcgtttaa
Protein Sequence: MNEGSEYSIHSICRICLNHLRNDAVYDLFLVPGLAKKLCVCTSLSVEQHDGFPKNLCTQCYTKLEDLHGFQKMCVDSVQKFQDMVANNYFTPVISDINQIDNVDVLNIAPPEGEMEEDRINFDPLLNTKIEVIENEDDVFKMLEDVDKDVEDVDKEEESSSESEEENDNDDGDGDGDGDFEVNSSESDDAMPLSRLRGSTRARASKAKARKKTKRNNDNDDDNSSSSESNDDDDDDDNDDDDDDARPRSKPKRKRIPAGERDRHKLIDCHICHQKFKKAIRYEEHMKHHNDLLPFQCTVESCKKGFTTAGGLRLHMDHAHIEFSEVHACTFEGCDKTFPRSVLLTFHMKKVHKVAKPDVKKHACTECEKVFRCPTALKKHMYKHTGEELPFACEICGKRFHIHSVLRDHLLRHAGVKNHVCPYCGVGKTTRQEWNKHILTHTREKQFQCRQCDHASHNKQALSNHVKVVHMKIKNFACQYCGKTFGKSHACKIHERLHTGENCCECKICGKIFLFEKRLTKHLQLHEKRDIPPAATAVKPQDDGQQSTPSGSQQDPQSHMTTEPVDVKPLPVVPPKPKNSHRVERVDISQLAGTSVNPISSVSVPSWSPQVNFTKKEGQHICPGCGRGFNHIGNMKLHYKIIHEKVKDFACRYCPKRFAKAQYLRNHEYIHTGEKPFECKICGKHFRQEQVLKTHLKVHDKPPKQPKEKKPPKPSVSKARGLKVELNKKQPKIHDEYQDPAAERAAATAALLAQQIEENEAKRKQEEANRKIQEAACEQLNRLQKQIQSEKGSYDSYYGQKAEADGINPDVLKLDHV

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00610124;
90% Identity: iTF_00608675;
80% Identity: -