Basic Information

Insect: Drosophila limbata
Gene Symbol: grau
Assembly: GCA_963924055.1
Location: OZ001355.1:8108338-8110273[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 8 2.4e-06 0.00024 22.0 0.2 2 23 294 315 293 316 0.94

2 8 3.2e-06 0.00032 21.6 0.8 1 23 324 346 324 346 0.96

3 8 0.094 9.5 7.5 1.5 1 23 354 379 354 379 0.90

4 8 0.0018 0.19 12.9 0.5 3 23 386 406 385 406 0.97

5 8 0.067 6.8 8.0 0.2 2 23 415 438 414 438 0.86

6 8 9.6e-05 0.0097 16.9 2.0 1 23 445 468 445 468 0.96

7 8 7.7e-06 0.00078 20.4 0.8 1 23 473 495 473 495 0.97

8 8 6.8e-05 0.0069 17.4 3.6 1 23 501 524 501 524 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	8	2.4e-06	0.00024	22.0	0.2	2	23	294	315	293	316	0.94
2	8	3.2e-06	0.00032	21.6	0.8	1	23	324	346	324	346	0.96
3	8	0.094	9.5	7.5	1.5	1	23	354	379	354	379	0.90
4	8	0.0018	0.19	12.9	0.5	3	23	386	406	385	406	0.97
5	8	0.067	6.8	8.0	0.2	2	23	415	438	414	438	0.86
6	8	9.6e-05	0.0097	16.9	2.0	1	23	445	468	445	468	0.96
7	8	7.7e-06	0.00078	20.4	0.8	1	23	473	495	473	495	0.97
8	8	6.8e-05	0.0069	17.4	3.6	1	23	501	524	501	524	0.98

Sequence Information

Coding Sequence: ATGGAACCACAAATTTGTCGTCTGTGCTTGCGTGGTTGTGGCTCCCAGATGTGTCTCCAAATCTTTGGTGATGCAGCAGGTGCTGCTGCGGGTAATCTGCCAAACGTTGCGGAAGTTCTACGCCAGCACTTTTGGTTTGAGtTACTGCCAAACGATCCAATGTCGAAAGTTGTTTGCAATGTCTGCTGGACTCAGGTTTCCGAGTTCCATCAGTTCTATGTGTCCATTCAAGAGGCTCAGGTTATTTACGCCAACGCACCGAAATTCAAGCAGGACCCCGATCCAGACATGCTGAGTGCTTCGTGGCCAGAGGAAATATTGATGTCAGCTAATGAACTGACTGCCGATGGGAATAACGACTGTCGCAGCACGCAGCTAAATGTGAATCCCTTAGATGAATTAGACCTAGAGATGTCAACGTATGCAGACACAGATGTGGAGGatcaaaaagaaatcaaattggAGAGACTATCGCCAGACGAGTTCCTGAACGAAATCGACGATGTGGATCTTATTGTTACCCGCAGTGGCTTAAAACGTAAACGTGAAACTGAACCTATTGAGAAGCTAAAGACATCCAAAGTAAAAAGATCAGCACGGTGCAAGAATCACGAAAAGCGCAGGACCATAGCAAAAAGGACATTCAAGACACAGCAGTGGCCACCGTTCTGTAAAGAGGACGAGGAGTTAATCAGACGCTATGTCGTAATGGGCTGTGAGCTGTGCATCTTTCTGGCTGACGATTTCGATGGCATCCGAGATCACTTTAAGGATAAGCATCCCAACGAGCGACCCTACATTAAATGTTGCGGACGCAAATTGAATAAACGTTGCCTAATAGTCGAGCATGCCCGACGTCACGAGAATCCAGAGTACATTAAATGTAATGACTGTGGCAAAGTGTTTGCCAATTCAAGTGTTTTACGTGCCCATTGGTTGGCTCATCACGTGCCGGACGAGGAATGCGATTTTCAGTGCGAGGAGTGTGGCAAACGATTCTCGCGCCGGAATCTCCTGGAGCTGCATAAAGGCTCACATGTGCCGGCCAACGAACGCAAGTTCATCTGTCCAGAGTGCCCCAAACATAATGCCTTTGCAACCGAATACCACATGCAGGTGCATATAAGTATGCAGCACCGCAAGGCAGCCAATATATGCCATGTTTGTGGCAAAGAGATCAAGGATAAGGCTGTTTTTGAGAAACACGTTCGCCTGCATTTCGAGGACAGCGGACCACGCATTAAATGCCCACGTCCGGACTGCGAAAGCTGGCTGAAGGACGAGGACAATTTGAAGCAGCATTTAAGGCGACATAACGACGAGGGTAAATCTTTTATCTGCTCGGAATGTGGCAAAAGCTGTAAGAACTCGCGTGCGCTCATCGGTCACAAGCGCTATTCCCACTCGAATCAAATCTATACCTGCGAACAGTGCGGCAAGACCTTTAAAAAAGATATTAGCCTTAAGGAACACATGGCTCAGCATACTGGGGAGCCCCTTTATAAATGTCCCTTCTGCCCGCGGACATTTAACTCAAATGCCAATATGCATTCCCATAAAAAGCGTATGCATCCAAATGAATGGGATCATTGGCGTAAAACGAAAACGGGTAGCTCCCAAAAGGTGCTCCCCAGTGCACAGGTGTCGCAAATGTTCAGAGAAGATCCTGAGACGGCCGCCattccaaatatttcaaacatATTTTAG
Protein Sequence: MEPQICRLCLRGCGSQMCLQIFGDAAGAAAGNLPNVAEVLRQHFWFELLPNDPMSKVVCNVCWTQVSEFHQFYVSIQEAQVIYANAPKFKQDPDPDMLSASWPEEILMSANELTADGNNDCRSTQLNVNPLDELDLEMSTYADTDVEDQKEIKLERLSPDEFLNEIDDVDLIVTRSGLKRKRETEPIEKLKTSKVKRSARCKNHEKRRTIAKRTFKTQQWPPFCKEDEELIRRYVVMGCELCIFLADDFDGIRDHFKDKHPNERPYIKCCGRKLNKRCLIVEHARRHENPEYIKCNDCGKVFANSSVLRAHWLAHHVPDEECDFQCEECGKRFSRRNLLELHKGSHVPANERKFICPECPKHNAFATEYHMQVHISMQHRKAANICHVCGKEIKDKAVFEKHVRLHFEDSGPRIKCPRPDCESWLKDEDNLKQHLRRHNDEGKSFICSECGKSCKNSRALIGHKRYSHSNQIYTCEQCGKTFKKDISLKEHMAQHTGEPLYKCPFCPRTFNSNANMHSHKKRMHPNEWDHWRKTKTGSSQKVLPSAQVSQMFREDPETAAIPNISNIF

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00496062;
90% Identity: iTF_00583914;
80% Identity: -