Basic Information

Insect: Drosophila limbata
Gene Symbol: T
Assembly: GCA_963924055.1
Location: OZ001352.1:9556755-9571037[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 17 1e-06 0.00011 23.1 3.7 1 23 221 243 221 243 0.98

2 17 0.00047 0.048 14.7 4.4 1 23 249 272 249 272 0.98

3 17 0.13 13 7.1 4.5 1 21 278 298 278 299 0.94

4 17 2.2e-05 0.0022 18.9 2.2 1 23 726 748 726 748 0.97

5 17 0.00024 0.024 15.7 0.2 1 23 754 777 754 777 0.97

6 17 0.02 2 9.6 0.7 1 23 783 806 783 806 0.90

7 17 0.0034 0.34 12.1 6.4 1 23 840 862 840 862 0.95

8 17 0.011 1.2 10.4 1.0 1 23 868 890 868 890 0.98

9 17 0.00021 0.021 15.9 0.6 1 23 896 918 896 918 0.98

10 17 0.013 1.4 10.2 4.8 1 22 924 945 924 948 0.91

11 17 1.4e-05 0.0015 19.5 2.6 1 23 1268 1290 1268 1290 0.97

12 17 0.00011 0.011 16.7 0.1 1 23 1296 1319 1296 1319 0.97

13 17 0.02 2 9.7 2.4 1 23 1325 1348 1325 1348 0.85

14 17 0.0034 0.34 12.1 6.4 1 23 1382 1404 1382 1404 0.95

15 17 0.017 1.7 9.8 1.5 1 23 1410 1432 1410 1432 0.98

16 17 0.00074 0.075 14.1 0.5 1 23 1438 1460 1438 1460 0.98

17 17 0.013 1.4 10.2 4.8 1 22 1466 1487 1466 1490 0.91

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	17	1e-06	0.00011	23.1	3.7	1	23	221	243	221	243	0.98
2	17	0.00047	0.048	14.7	4.4	1	23	249	272	249	272	0.98
3	17	0.13	13	7.1	4.5	1	21	278	298	278	299	0.94
4	17	2.2e-05	0.0022	18.9	2.2	1	23	726	748	726	748	0.97
5	17	0.00024	0.024	15.7	0.2	1	23	754	777	754	777	0.97
6	17	0.02	2	9.6	0.7	1	23	783	806	783	806	0.90
7	17	0.0034	0.34	12.1	6.4	1	23	840	862	840	862	0.95
8	17	0.011	1.2	10.4	1.0	1	23	868	890	868	890	0.98
9	17	0.00021	0.021	15.9	0.6	1	23	896	918	896	918	0.98
10	17	0.013	1.4	10.2	4.8	1	22	924	945	924	948	0.91
11	17	1.4e-05	0.0015	19.5	2.6	1	23	1268	1290	1268	1290	0.97
12	17	0.00011	0.011	16.7	0.1	1	23	1296	1319	1296	1319	0.97
13	17	0.02	2	9.7	2.4	1	23	1325	1348	1325	1348	0.85
14	17	0.0034	0.34	12.1	6.4	1	23	1382	1404	1382	1404	0.95
15	17	0.017	1.7	9.8	1.5	1	23	1410	1432	1410	1432	0.98
16	17	0.00074	0.075	14.1	0.5	1	23	1438	1460	1438	1460	0.98
17	17	0.013	1.4	10.2	4.8	1	22	1466	1487	1466	1490	0.91

Sequence Information

Coding Sequence: ATGTCACAATTAGTTATCTGCAGGACTTGTGGTAGTAAGATATACAGCAGTAATGCCAAGAACCTTTTCGATACGGAGGACAATGAAATTGTAGCGAAGATCCAAATATTGACGGGAATCTATATTAATGAGGAGCAGCATATGCCCAAGGACATTTGTGGCAGTTGTCATTTGGATTTAAACCATTCAATAGCCTTTCGGGAGCGATGTATTAAAACGCATAAACTTCTGTTGATGTTGAGTGAAAGACGAAGGAAGCGAGCGACTTTAGACGCACTGAAGACAGCAATAATCAAATCTAAAAAGCATGCTCAACTTGAGATTGCAAGGGTTTCCATCGAGCCGCATCATCCATTAATCGAACAGAAACCAAAGCAAATTCACACACGTTCAAAGAGTCATATACGTAAAACGAAAATATCTGAAGAAGTTCCAAGCATTGTTCAGCAGCAACCCAATACATTCTGTAAAGAAGAAGCACAACAGGACGAATGTCCCAATTTTGAGCAGTCTGTACATTCCGATAACGATAATGATGAGTCGCAGGAGGAAAGTCACAGTGTTGAGAACACTGCAGATTCGGATAACGAAATAGCACATGAGCCCCAAAGGAATCCAAACCGTCAAGTTAGCCAGCCCGGCGCTACGGGAGCCAAAAAATATGTGTGTCACCAATGCGGCAGATGCTTCGCAGATTCCAGCAACTTTAAAGTACACATTTTGCGGCATACGGGAGTCAAGGATTTTAAATGCACCGAATGTGGCGCAAAATTCTTTACTCGCCATCTACTGCATTTGCATATTCGTGTAAGGCACCTGGGGGAAAAGCCGTACGCGTGTAAATATTGTGACCAGCGTTTTTTTACGAGCACTTCTCGCTGTCGGCATGAACGTTTTTGCCGCAAGCAAGTGCAAGGCGTAAAGTATATTCATACACCGAAATGTTTAGTGAAAAGAGCATTGTGGGAGCAAGCTCTGGGCTGCAGCTTTGGTGAGCACTCCAAAATTTGCGACACGCATTTTAATGCTTCACAGTGGAAGTCGGCACCCAAGAATGGGAAGATCTTTAAAAGAAGGCGACTGAACGATGATGCTGTTCCGCAAAGAGAGCCAGaaccaaaaatttttaaactaggCTACGGCGATTCGAACACGCAAACAGACTTTCAGAGAAGTCCTAATGCTTCGAAAGGATGCAAACCGATTAAAAATCGCAATGAGGACTTTAAAAAGGAGGGCATCCAAGGAGGATTACAATTTCAAATGGgATTGCcaagcaacaataaaaacgaACGGGAGAAATCAAAGAAGCGCAAGAACAAAAATTTGGTCCCAGAGCTGCTCGAGAATGCAGAAGCGCTGGAGGCAGCTGTTCCAAATTTTGTTAGTTCCACTGGAAAGGCCTTCGTTCCGTTCCCCTCCGCACCTTCAGAGAAAGATCCCTTGGCTGAGGAACAGGTGAAGGCAGATAATGCTACAACGAGCTATGAAAACGATGTTACTTTGAGCAATAAGATGAAATGTCGCACCTGCTTGCGTCCTTTGCTTGTTGATGACGATGCGAAAGATCTAAGCAACGTAGAAAACGCTGTGATGTTATATCacattgaatttattacaGGAATTTGgATACAATGCAACGATGAAATTTCTCGATTCATGTGCTCCCGTTGTGTTGATAACTTACGCACAGCCATTGAGTTCCGAGAAACATGCATACGGACAGAACTTCTGCTCACAGGTGGCGACGATGTCGATCTTCCAGAGAACGGCATCGAATTGTGCGATGATAAGGTCGAATCGCAGATGACTGACGATATGAAGGAGGAAGATTTCATATCTATATTTCCGGCTGATGGAGAACATGGACAAACAACTGTAATTGAGCCGTTAACACGATCAGTAACTAAAATATCGGGCCAGATATTACATCCGGCTGAAACGGATTCAAGTAGCCTTGTTTTGGGTGCCCAGATCTATGAGGATCTTTTAAATGAATACCAGGAAAAGGAGAAGActacacaaacaaaacaaaagaaagcaTCGAACCCAAACACCCAGCCGGCAAAGAAGAGGATACAAATACCACGGGAGCCAGCGCCCAGACGTACTAAACAAACGAGAGAGGAAAAAAATCGGATACGCCGTGAGCAGAGAAAAGCCTTGCCCCGCAATCATGTGTGCGATCAGTGCGGTGCATCCTTTCGAATGAGAGACCATCTCACAATACATATGCTGCGGCACACGCGCACCAAGAACTTTCCATGTCCGGAATGCCCCAAGCAGTTCTATGATGCTTACATGAGAAACATGCATATCCGTGTGCGCCACCGAGGCGAACATCCCTTTGTCTGCAATTATTGTCCGAAAGCATTTGGTTCATCCACCACACGTTACCTACACGAGAAAAACGTTCATGGAGCATCTGCGCGCATTCACAGGAATGTAAATAACCAAAGGATATTTCTCAAGAAAAGTCAGACGCAGTCAGAGTCAGTTGTAGACGAATTTGGTCGTCACTGTTGTAGTTATTGCGATAAAAGCTATGTCACAAAATGCGCACTCAACTGGCATGTAAATCAACATTTAGGCCTGACTCCTTTCAAGTGCAAGTCCTGCGATATGAAATTTCCGAATCCCCAAGCGAAACTCCGTCACGAGATGAGGCACGATAGTAAGCGTCCCTTTGAATGTGACATTTGTCTCAAAGGATTCTACACAAGGATTAATCTCAAATATCATGAACGGATTCATACTGGCGAACGTCCTTACAGgtGTGACATTTGCGATTCCTTTTTCCGATACAAGTTCAACTTGCACTCGCATCAGTTTAGCAAAATGCATAAGGATAATCTGCTTAAGGCGCAAATGGAGAAGATTGTCGAAGACTCAAgATTGCCACGCAACAATAAAAGCGAACGGGAGAAATCAAAGAAGCACAAGAACAAAAATTTAGTCCCAGAGCTGCTCGAGAATGCAGAAGCGCTGGAGGCAGCTGTTCCAAATTTTGTTAGTTCCACTGGAAAGGCCTTCGTTCCGTTGCCCTCCGCACCTTCAGAGAAAGATCCCTTGGCTGAGGAACAGGTGAAGGCAGATAATGCTACAACGAGCTATGAAAACGATGTTACTTTGAGCAATAAGATGAAATGTCGCACCTGCTTGCGTCCTTTTCCTGTTGATGACGATGCGAAAGATCTAAGCAACGTGGAAAACGCTGTGATGTTATATCacattgaatttattacaGGAATTTGGATCCAATGCAACGATGAAATTTCTCGATTCATGTGCTCCCGTTGTGTTGATAACTTACGCACAGCCATTGAGTTCCGAGAAACATGCATACGGACAGAACTTCTGCTCACAGGTGGCGACGATGTCGATCTTCCAGAGAACGGCATCGAATTGTGCGATGATAAGGTCCAATCGCAGATGACTGACGATTTAAAGGAGGAAGATTTCATATCTATATTTCCGGCTGAAGGAGAACATGGACAAACAACTGTAATCGAGCCGTTAACACGATCAGTAACTAAAATAACGGGCCAGATATTACATCCGGCTGCAGCGGATTCAAGTAGCCTTGTTTTGGGTGCCCAGATCTATGAGGATCTTCTAAATGAATACCAGAAAAAGGAGAAGActacacaaacaaaacaaaagaaagcaTCGAACACAAACACCCAATCGGCAAAGAAGAGGAAACAAATACCACGGGAGCCAGCTCCCAAACGTACTAAACAAACAAGAGAGGAAAAAAATCGGATACGCCGTGAGCAGAGAAAAGCCTTGCCCCGCAATCATGTGTGCGATCAGTGCGGTGCATCCTTTCGAATGAGAAGCCATCTCACAATACACATGCTGCGGCACACGCGCACCAAGAACTATCCATGTCCGGAATGCCCCAAGCAGTTCTATGATGCTTATATGAGAAACGTGCATATCCGTGTGCGTCACCGAGGCGAACATCCCTTTGTCTGCAATTATTGTCCGAAAACATTTAAAGCTTCCAGCTTGCGTTATCTGCACGAGAAACACGATCATGGAGCATCTCCGCGCATTCACAGGAATGTAAATAACCAAAGGATATTTCTCAAGAAAAGTCAGACGCAGTCAGAGTCAGTTGTAGACGAATTTGGTCGTCACTGTTGTAGTTATTGCGATAAAAGCTATGTCACAAAATGCGCGCTCAACTGGCATGTAAATCAACATTTAGGCCTGACTCCTTTCAAGTGCAAGTCCTGCGATATGAAGTTCCCGAATCCTCTATCGAAAAACCGTCATGAGATGAGACACGATAGTAAGCGTCCCTTTGAATGTGACATTTGTCTCAAAGGATTCTACACACGGATTAAGCTTAGAGATCATGAGCGGATTCATACTGGCGAACGTCCTTACAGGTGTGACATTTGCGATTCCTTTTTCCGATACAAGTTCAACTTGCATTCGCATCAGTTTAGCAAAATGCATAAGGATAATCTGCTCAAGGCGCAAATGGAGAAGATTGTCGAAGACTCAAGTTCATCGTCAGATTAA
Protein Sequence: MSQLVICRTCGSKIYSSNAKNLFDTEDNEIVAKIQILTGIYINEEQHMPKDICGSCHLDLNHSIAFRERCIKTHKLLLMLSERRRKRATLDALKTAIIKSKKHAQLEIARVSIEPHHPLIEQKPKQIHTRSKSHIRKTKISEEVPSIVQQQPNTFCKEEAQQDECPNFEQSVHSDNDNDESQEESHSVENTADSDNEIAHEPQRNPNRQVSQPGATGAKKYVCHQCGRCFADSSNFKVHILRHTGVKDFKCTECGAKFFTRHLLHLHIRVRHLGEKPYACKYCDQRFFTSTSRCRHERFCRKQVQGVKYIHTPKCLVKRALWEQALGCSFGEHSKICDTHFNASQWKSAPKNGKIFKRRRLNDDAVPQREPEPKIFKLGYGDSNTQTDFQRSPNASKGCKPIKNRNEDFKKEGIQGGLQFQMGLPSNNKNEREKSKKRKNKNLVPELLENAEALEAAVPNFVSSTGKAFVPFPSAPSEKDPLAEEQVKADNATTSYENDVTLSNKMKCRTCLRPLLVDDDAKDLSNVENAVMLYHIEFITGIWIQCNDEISRFMCSRCVDNLRTAIEFRETCIRTELLLTGGDDVDLPENGIELCDDKVESQMTDDMKEEDFISIFPADGEHGQTTVIEPLTRSVTKISGQILHPAETDSSSLVLGAQIYEDLLNEYQEKEKTTQTKQKKASNPNTQPAKKRIQIPREPAPRRTKQTREEKNRIRREQRKALPRNHVCDQCGASFRMRDHLTIHMLRHTRTKNFPCPECPKQFYDAYMRNMHIRVRHRGEHPFVCNYCPKAFGSSTTRYLHEKNVHGASARIHRNVNNQRIFLKKSQTQSESVVDEFGRHCCSYCDKSYVTKCALNWHVNQHLGLTPFKCKSCDMKFPNPQAKLRHEMRHDSKRPFECDICLKGFYTRINLKYHERIHTGERPYRCDICDSFFRYKFNLHSHQFSKMHKDNLLKAQMEKIVEDSRLPRNNKSEREKSKKHKNKNLVPELLENAEALEAAVPNFVSSTGKAFVPLPSAPSEKDPLAEEQVKADNATTSYENDVTLSNKMKCRTCLRPFPVDDDAKDLSNVENAVMLYHIEFITGIWIQCNDEISRFMCSRCVDNLRTAIEFRETCIRTELLLTGGDDVDLPENGIELCDDKVQSQMTDDLKEEDFISIFPAEGEHGQTTVIEPLTRSVTKITGQILHPAAADSSSLVLGAQIYEDLLNEYQKKEKTTQTKQKKASNTNTQSAKKRKQIPREPAPKRTKQTREEKNRIRREQRKALPRNHVCDQCGASFRMRSHLTIHMLRHTRTKNYPCPECPKQFYDAYMRNVHIRVRHRGEHPFVCNYCPKTFKASSLRYLHEKHDHGASPRIHRNVNNQRIFLKKSQTQSESVVDEFGRHCCSYCDKSYVTKCALNWHVNQHLGLTPFKCKSCDMKFPNPLSKNRHEMRHDSKRPFECDICLKGFYTRIKLRDHERIHTGERPYRCDICDSFFRYKFNLHSHQFSKMHKDNLLKAQMEKIVEDSSSSSD

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: -
90% Identity: -
80% Identity: -