Basic Information

Insect: Drosophila leontia
Gene Symbol: -
Assembly: GCA_008042735.1
Location: VNKB01016629.1:60076-63996[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 14 7.5e-05 0.0065 17.0 0.4 1 23 167 190 167 190 0.96

2 14 0.0015 0.13 12.9 3.1 2 23 239 261 235 261 0.90

3 14 0.0064 0.55 10.9 0.8 1 23 358 381 358 381 0.93

4 14 0.0016 0.14 12.8 3.0 2 23 430 451 429 452 0.94

5 14 0.00058 0.05 14.2 0.4 1 23 518 541 518 541 0.92

6 14 5.8 5e+02 1.6 0.1 2 14 560 572 559 584 0.83

7 14 0.00059 0.05 14.2 3.3 2 23 592 614 592 614 0.96

8 14 0.091 7.8 7.3 0.5 1 23 706 729 706 729 0.95

9 14 4.3e-05 0.0037 17.7 0.3 1 23 764 787 764 787 0.93

10 14 0.0036 0.31 11.7 1.5 2 23 837 859 836 859 0.95

11 14 0.016 1.4 9.7 1.8 1 23 945 968 945 968 0.91

12 14 0.0018 0.15 12.6 1.4 1 21 1020 1040 1020 1041 0.95

13 14 1.6 1.4e+02 3.4 0.1 3 23 1073 1096 1071 1096 0.81

14 14 3.6 3.1e+02 2.2 0.3 1 11 1116 1126 1116 1140 0.72

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	14	7.5e-05	0.0065	17.0	0.4	1	23	167	190	167	190	0.96
2	14	0.0015	0.13	12.9	3.1	2	23	239	261	235	261	0.90
3	14	0.0064	0.55	10.9	0.8	1	23	358	381	358	381	0.93
4	14	0.0016	0.14	12.8	3.0	2	23	430	451	429	452	0.94
5	14	0.00058	0.05	14.2	0.4	1	23	518	541	518	541	0.92
6	14	5.8	5e+02	1.6	0.1	2	14	560	572	559	584	0.83
7	14	0.00059	0.05	14.2	3.3	2	23	592	614	592	614	0.96
8	14	0.091	7.8	7.3	0.5	1	23	706	729	706	729	0.95
9	14	4.3e-05	0.0037	17.7	0.3	1	23	764	787	764	787	0.93
10	14	0.0036	0.31	11.7	1.5	2	23	837	859	836	859	0.95
11	14	0.016	1.4	9.7	1.8	1	23	945	968	945	968	0.91
12	14	0.0018	0.15	12.6	1.4	1	21	1020	1040	1020	1041	0.95
13	14	1.6	1.4e+02	3.4	0.1	3	23	1073	1096	1071	1096	0.81
14	14	3.6	3.1e+02	2.2	0.3	1	11	1116	1126	1116	1140	0.72

Sequence Information

Coding Sequence: ATGGAAGGCATGGACCTGTGGACATCGATGTTCTCCTCCGAGTTCGAGGACGGCGAGCCAGAAGGGGGCGGCGAGGCCGAGCTGCTGGAGGGAGGGGAGGATGGCGGGCAGTATGGCAACGGTAATGGTGACTTTATGGACGACACGGCTATCCTGGAGGCTGGGGATGGCGTGGACGATCTGCTAGATGGCGAAGACGATGAGCGGGAGGAGGATGAGCACGAAGATGGCACGGAAAAGGGGCCTAAGAGACCGGAACCGGACGACGATGCACTCTTCGACTTTGAGCTGGAGCCGATTGTGAGTATTGGAGAGCCCACGCCGGGTTCGGCTCTGGCTCCAGCTGGTCCAATGGGCGCCCAAGTGCGTCCAGCCCTGCAGCGGCATTCACTGCCACCCCTGAGTCGGCCCATTGGGTATTCGGTGCGGCCAACTACCTCGCAAATCAACGCCACCGATGAGAACGGTGTGCCCATTAACTATGAGCTGGGCGTTGTGTACATTTGTCCCGCCTGCGGCGGAGAGTTCCGGCAGCAAGATCACTGGAAGCGGCACATGAATCAAATCCACAGGTACAACACCCTGCGTGGCCTCAACTTTGCGCCGCTGGACAAGCTGTATCAGCGCTGCAAGGAGTGCCACAAGCGAATTGCCATGCACAGCCGAGAGAACCTGCTGAAGCACAAGTTCACGCACCTGCCCTTCCGGTGCACCAAGTGCTACATTTGCAAGCGGGAGTACAAATACAGGCAAGATCTAATGGTGCACCTACGCATGGTCCACTGCGATGAAGTGGTGGCCATGATGCGGGAGGGTTACAATGCTGCCGGACGCAAGACCCGTGTCAGAGAGTCCCGGACAGAGCAAATGCAAAGGGAGAAGAGTTTTCTGGAGGGTGAGGACCTGGATCACATTGAGGTGCGAAATGAGCTGCTAGAACCGGATATTGATGAGGAGTCCGGCGGCCTggagcatcatcatcagccaCTGCTGGTGGAGGAGACGCCTCACAAGAAGCGAAACCGTGGCAGTGGCGAAGAAGCCAGCGAGCTGTGTGAGGATTACATCCACTACATGTGCCCCGATTGTGGGACCGAGTGTGACACCCATGCCCAGTGGAGCCAGCACATAGAGTTCGTCCATGACTATGTCAGTCGGCGTGGCCTCAACTTTCGGAGCGTGGATATGCAGATGCAGTGCCTCGAATGCAAGAAGATTGTGATCCCCAACACCATCAAGTCGCTGCGCTCCCACAAATTCAGTCACCTATCGCATCCCGAGTGGCTGCGCTGCAAGCTCTGCTACAAGGGCTACACGGATCATGCGGAACTGGTTAGACATCTGCTGAAGCATCATCATCTGGAGAGTCTTATGTCGGAGGAGCCGGGCCTGGAAGAGGAGGATGCTTCAGCCACCATAGATGGGGGAAATGAAGGTGAAGacaacaatggcaatggcaccGCCTTGGACGAGGACTCACCCTACTTTGAGGACGCCCCCCGACGCGGCGGTCGCATTAGCAGCGATGACATTTTCGAACCCCACATCGACTACCTCTGCCCGCAGTGCGGCAAGGAGTTCATCGAGAAGAAGCACTGGCGCACCCATGTGGTCATGGCGCACAGCATGAACGACCTTTCCAAGCTGAACTTTGAGATGATCAACGAACGGCAGTTGAAGTGCACCGAATGCGAGAAGATCATCACGAATGCCTATGGCATACAGAATGCCCAGCAGCACAGGATCACCCATCTGCCGTTCAAGGCATATGCCAGATGCCGCAAGTGCCACAAGTCCTACACAGATCGCAAGGGTCTCGTCAAGCATCTGGCCACCTATCACCGGATTGGGTGTGAGGCTAGAAAgtccggaggaggaggagctgcatcTTTACCCAAGCAGCCACGCAAGCAGATTGTGACCGTGGCCAATGAGACGTACGAGATTATCTACCTGGACGATGTGGTGGAGCAGGGCTCCAACTTGGAGGAGGAGAATGATTTTGGGGAGCAGATGCTGGCTGATGAGGATGATTATCCGGTTATtcagccaccaccaccgccgctaCAGCGGCATGTGCCGCCTCCACCACGTCCCTCCTCCACTCAGCAACGCTACAAGTGCGTCCACTGCAGCGTTCTCTTCCCCACCCAGATGGCCGTGCGGGTGCACATCAGTGAGAAGCATCCCAGGAAGCCCCATCAAATGGGCAGAAGACATCGCCATTCGCTTTCGAATTCTGGAGGAGCGGACTCCTCGGGCCTTACCACCGTGGAGCAGAACTACATATTCCTGTGCCCCTCCTGCGGCAAGGAGTACAAGACGCAGTACGAGTGGCGGCGCCACATCAACGAGGAGCACAACTTTGACAAGCGCAACTATCTGAACATGCGGCAGTTGGACAAGTATCGTTATCAGTGCACCCAGTGCAAGGACATTGTGTGCAACTCGAAGCTGAAGGGTCTACAGGATCACCACTTCCGTCACCTGCCCTATCGCCTGTATCTCAAGTGCTTGGTCTGCGGCACCTGCTACAACCACAAGCCGAACATAGCGGCGCATCTCAGGGCGCGACACAACATCTTCGACAGGGAAACGCCACTGATAGTCAagccgaagagtgtctataatCGTGGCAAGGATGGTGAAAGAGAAAAGGTCTCCCTAGCCACACCCGCTCCCTCAGCCGTCTCTCCAcctggctgctcctcctccacctcctcTCGCACGCTTAAGCCCCAACCTGGAGATTTGCCCACACGACCCGCCGGCCTGAACACCCTGGAGGACAGCATCTCCTACCACAATGCCGTGGACATGGACTTTATTACGTACTTCTGCCCCAAGTGCAACCAGAACTTTGACTCCCATGCCTTCTGGCGCAAACACATTGTGGAGCAGCACAACTTCAATAGTCGCGAGGGTTTGAATTTCCGGCAGATCGACAACCATCACTACCTGTGCCTGGAGTGCTACAAGCGCGTCACGGTGACCCACACCAAGGGTGCCATTGGTCAGCTGCAGTCGCACAAGTTCCGTCATCTGCCGCATCGCTCCTTCAAGTGTCTCACCTGTGACGCCTCGTTTGTGCGCAAGCAAATGTTCTTCAAGCACTTGAATCGTGACACCAATCGCTGTGACAATCGTCCCCAGCGCGAGTTGGACGACGAAGAGCCCAGCCAGGACTCGCAGCTAGGCACCATTTACCATCTGGCCTGTCCGCAGTGCGGCGATGACTTCAACACGCCCAGCCGGAAGCAGTGGCGAAATCACATCAATGTCCTCCACGGCCTGACCACGCTGGATCTGTTGCACATGGAGAAGGTGGATAGAGCGGAGGATCTATATCGCTGCCAGGACTGCAACGAGGAGCTGCAGACAAACCGGCAGTGGGTGCTGCAATACCACCGCTTCCAGCATCTCCCGCAGCCGGCCTACATACGCTGCCAGCTGTGCGAGCAGAGCAGTGAAAGGGATGCTTCAGTGGTGTCTGGGATGCACAGTCTACGCgaactgcagcagcatctgCGCAAGCATCATGCCACAACGGTGGGCGAGAACGAGATGCAGATGCTACGCGAACAAATAGcccaggaggagaaggagcagcaggaggagacaCTGGGCCTCGGTGGTGGAGATGAAGAGGATAACCAGGTGGGCCAGGACTCGGGGCCCTATATGCCGCTTCCGCCGCATTTATTGGACGATGGAGACGACGTAGAGTTTGAGGACCAGTATCTGCTGGGCTAG
Protein Sequence: MEGMDLWTSMFSSEFEDGEPEGGGEAELLEGGEDGGQYGNGNGDFMDDTAILEAGDGVDDLLDGEDDEREEDEHEDGTEKGPKRPEPDDDALFDFELEPIVSIGEPTPGSALAPAGPMGAQVRPALQRHSLPPLSRPIGYSVRPTTSQINATDENGVPINYELGVVYICPACGGEFRQQDHWKRHMNQIHRYNTLRGLNFAPLDKLYQRCKECHKRIAMHSRENLLKHKFTHLPFRCTKCYICKREYKYRQDLMVHLRMVHCDEVVAMMREGYNAAGRKTRVRESRTEQMQREKSFLEGEDLDHIEVRNELLEPDIDEESGGLEHHHQPLLVEETPHKKRNRGSGEEASELCEDYIHYMCPDCGTECDTHAQWSQHIEFVHDYVSRRGLNFRSVDMQMQCLECKKIVIPNTIKSLRSHKFSHLSHPEWLRCKLCYKGYTDHAELVRHLLKHHHLESLMSEEPGLEEEDASATIDGGNEGEDNNGNGTALDEDSPYFEDAPRRGGRISSDDIFEPHIDYLCPQCGKEFIEKKHWRTHVVMAHSMNDLSKLNFEMINERQLKCTECEKIITNAYGIQNAQQHRITHLPFKAYARCRKCHKSYTDRKGLVKHLATYHRIGCEARKSGGGGAASLPKQPRKQIVTVANETYEIIYLDDVVEQGSNLEEENDFGEQMLADEDDYPVIQPPPPPLQRHVPPPPRPSSTQQRYKCVHCSVLFPTQMAVRVHISEKHPRKPHQMGRRHRHSLSNSGGADSSGLTTVEQNYIFLCPSCGKEYKTQYEWRRHINEEHNFDKRNYLNMRQLDKYRYQCTQCKDIVCNSKLKGLQDHHFRHLPYRLYLKCLVCGTCYNHKPNIAAHLRARHNIFDRETPLIVKPKSVYNRGKDGEREKVSLATPAPSAVSPPGCSSSTSSRTLKPQPGDLPTRPAGLNTLEDSISYHNAVDMDFITYFCPKCNQNFDSHAFWRKHIVEQHNFNSREGLNFRQIDNHHYLCLECYKRVTVTHTKGAIGQLQSHKFRHLPHRSFKCLTCDASFVRKQMFFKHLNRDTNRCDNRPQRELDDEEPSQDSQLGTIYHLACPQCGDDFNTPSRKQWRNHINVLHGLTTLDLLHMEKVDRAEDLYRCQDCNEELQTNRQWVLQYHRFQHLPQPAYIRCQLCEQSSERDASVVSGMHSLRELQQHLRKHHATTVGENEMQMLREQIAQEEKEQQEETLGLGGGDEEDNQVGQDSGPYMPLPPHLLDDGDDVEFEDQYLLG

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00489664;
90% Identity: -
80% Identity: -