Basic Information

Insect: Drosophila leontia
Gene Symbol: -
Assembly: GCA_008042735.1
Location: VNKB01008922.1:24932-30745[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 14 0.0076 0.65 10.6 0.9 2 23 154 175 153 175 0.97

2 14 8.7e-05 0.0074 16.8 1.7 1 23 399 421 399 421 0.98

3 14 6.8 5.8e+02 1.4 2.7 1 23 427 450 427 451 0.91

4 14 0.13 11 6.8 2.1 1 23 473 496 473 496 0.93

5 14 0.0011 0.092 13.3 1.9 3 23 844 864 843 864 0.92

6 14 0.043 3.7 8.3 1.4 1 23 870 893 870 893 0.98

7 14 8 6.9e+02 1.1 1.5 3 23 931 951 930 952 0.72

8 14 0.0027 0.23 12.1 0.4 1 23 973 996 973 996 0.97

9 14 0.0012 0.1 13.2 0.3 1 23 1188 1211 1188 1211 0.93

10 14 0.016 1.4 9.6 5.0 1 23 1223 1245 1223 1245 0.98

11 14 6.5e-07 5.6e-05 23.4 0.5 2 23 1251 1273 1250 1273 0.97

12 14 0.03 2.5 8.8 2.4 4 23 1283 1305 1281 1305 0.87

13 14 1.1 97 3.8 1.6 1 23 1310 1332 1310 1332 0.93

14 14 0.052 4.5 8.0 0.3 1 23 1338 1361 1338 1361 0.94

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	14	0.0076	0.65	10.6	0.9	2	23	154	175	153	175	0.97
2	14	8.7e-05	0.0074	16.8	1.7	1	23	399	421	399	421	0.98
3	14	6.8	5.8e+02	1.4	2.7	1	23	427	450	427	451	0.91
4	14	0.13	11	6.8	2.1	1	23	473	496	473	496	0.93
5	14	0.0011	0.092	13.3	1.9	3	23	844	864	843	864	0.92
6	14	0.043	3.7	8.3	1.4	1	23	870	893	870	893	0.98
7	14	8	6.9e+02	1.1	1.5	3	23	931	951	930	952	0.72
8	14	0.0027	0.23	12.1	0.4	1	23	973	996	973	996	0.97
9	14	0.0012	0.1	13.2	0.3	1	23	1188	1211	1188	1211	0.93
10	14	0.016	1.4	9.6	5.0	1	23	1223	1245	1223	1245	0.98
11	14	6.5e-07	5.6e-05	23.4	0.5	2	23	1251	1273	1250	1273	0.97
12	14	0.03	2.5	8.8	2.4	4	23	1283	1305	1281	1305	0.87
13	14	1.1	97	3.8	1.6	1	23	1310	1332	1310	1332	0.93
14	14	0.052	4.5	8.0	0.3	1	23	1338	1361	1338	1361	0.94

Sequence Information

Coding Sequence: ATGGCTTTGAATAAACGGATTAACCCGAACCCGGACGCCCTAGCGGGCGTCGCAGAGCTAAACTACAAATTTGCGTGTCGCTGCTGCCTGAAAGTGGACGCAGAGTTCATTAAGCTAGAATCGGTGTCGGTGGCGCGTAGCCTGGACCCAGCCAGCGAGGAGGATAAAATTTCGCTCCTGCGATGCCTTCTCTTCTGCGTGCGCGCCGAGAACGCGGCGGAGCTGCCGCAGTACATTTGCGTTGAGTGCAGCAAGAGCCTGCAAGTCGCGTACTACTTCCTGCAGAACGCAGTGCGTGCCCACGAGATCCTTTGCCGCAAGCTGTGTCCCGGCAAGGTATGGAACGCGGAAGGCAGGCGCTTCAATGGGGCTTTGAGCCAGCGCTTGCAGCCATCGCCGTCTCCGAAGGAGACGGCGACTTCGGGGGACAGGACGAGGCCTCTGAAGAGCATGCGGCAAGAGTGCCAGGTGTGCGGCGGTATCTTCCACAGTCGCATGGAACTCAAGCTGCACCTCCGCCAGCACACAGacGGAATCACTTACCACTGCAAGATGTGCAATTTCACCACGCTCAAACAGCGCCAGCTGCTGGAGCACTATCGCTGCGATCACGCCATGACCCCCAGTCAGGCGGAGGAGCACGTTAAGGCGAGTCCACTGCCGATATCTCCCATTAAGGAGGATGAGGTCAAAGCAGTGTGCACGCTGGAAGACATGGAGCTGCTTATACCCACGGTGCTTACGCCGGACGACTACGCTCAGCCCCCGATTGACTCGGAACAGCTGCGCGACCTCGATCAACAGCTGGCCGCCAGTATGGGCGACGCAGTGACCGGAGTGGACACCCTCACATCCACATTGCCGCCCATGGACACGGCGCACAATGTGAGCATTGGCACAGAGTATCTGGTCCTGCCGGATGGATCCCTGCAGCAGGTCAACGGAGGCGGCGTGGTTATTGAGTATATTGACGACAGTAAGAcgcagccaccgccaccaacTCCTTCCAATCCTCCGCACATCAACATCAGCTTGCAAAATCTCCTCGGCAACCATGACGAAAACGAGGGAATGGACATCGATGTCAACGAACTAATCGTCGAGGACATGATGATACATAAACCCACCATTTCCACTGCAGTTCCCAATCCACCCAAGCCAAAGCCAGTCATTGGCGTATCCCCAAATTACAAGCACAAGTGCAGCATATGTCCCAGAATGTTCTCCTCTGTGGCACGCCTGAAATCTCACCAGTTGACCCACAGCAATTTGCCCAAGTTCTTCTGCGACCAGTGCAACTTCTACTCGCTGCGCAGCGTTGATCTCATCGAGCACTACAAGACTACGCACCACCGGGTGGATGAGAACGGTGCGACCAGCCAGGACCCAGCGCCGGGGTCAGAGGAGACGGGCGTCTATTCATGCGACATGTGCCTCTTTGAGACGCGCACCTGCAGCCAGCTGAGGGTCCACTACACAGAGGGACACGCGATCCAGCCGACGGAAGTGCAGCTGCGTCCCAGTTGGACGAATAATAAGGCCACCAAAATGGAGCAGCCATTGTCGGGCAGGCAGCCAGAGCCCGCCGACCTGCCGGTGGCCATTAAATatCCGTCGATAGTTGCGGATGCGCAGGTGCCCGTGCAAATGCAGCAGGAAGTTCCAGTGCAGCAGCAAGTTCCAGTGCAGCAGCAAGTTCCAGTGCAGCAGCAAgtgcaaatgcagcagcaaatgcaaGCGCAGCAGCTAATACAGGcgcagcagcaaatgcaaatgcagcagcaaatgcaaGTTCAGCAGCAAAttcaagtgcagcagcagcagcaaccagtGGTGGTCACCACACCAACAACGCTCATCACACATACGAACAGCAACATAAACGTGGTGGTGGATACCACGCCGCTCTTCTATGCGTCTACCGTTTCCAGTGCGGTGCAGCAGGCAGTgacagtgccagtgccagagcAGACCATGCCAGTTCCAGAGCAGACCATGTCAGTCCCTGTGCAGGTCATGCCAATGCTTCCACCGGTGGCAACTGTGGTGGTGGAGTCCACCAACGAGAATAACAGCCATGCATTCGAAGTCTTTCCAAAAATCCAACCAACCAATGAGCAGGCAAAGGAACCCGTTCCCGTTGACCCCATACCGTCGGCCAATACATCCAATATCTCGATGTTTGGCGATATGCAGGATTTCATTGATAACACCGATGTGGCTGCCATATGCACGATACCAGCGGACGATATGCCCGTTGTGGATGGCGACGATATTGTGATTGATAATAACAATATCAGCCTAGACTTTGATGCCGAGAATCTATTTGAGGAattcgaggaggaggacgataCGGtgggcgacgacgacgagggggatgaggaggaggaggaagaggacgaGGCGGATAATGACGATGAGAATGACAACAACGATGCTGCCACAGATCAAAATCTACTGCTTACcagcgacgatgacgacgTGGACGACTTTGACGATGAGCAATCGAAGCATCTGCAGAAGCCCTACTGCATTTACTGCAACAAGAAGTTCACCAGTCAATACAAGTTCGAGAACCACATGTTTGTCCATCGCGgCCTGGCTCCCTATCGCTGTGAGCTGTGCACCAACCTCTACAACATGAAGCGCCTGCTGATCAGGCACTACAAGACCGTGCACAAGCGAATGCCCACCAGGGACATGGTCCAGGCCAAGGGCGATAAGGTACTGGTGACCCGTACCAACATAGAGAAGCTCTACATGGATGGAGTCAAAAgTCCCATGGTTATGTGCGCCAAATGCCCCTTTGAGTGCGAGGAGGATGGAGAAATGCGAAAGCATCTGAATGCCCATCACGGCATTAACGATGGACTGTCCATACATGCCAACGAGGTCTTCATTATACGCAAATTGCCTTTCGAGTGCCCGCGCTGTATTCGATCGTTTGCTGCCAAGGCCACGCTCACCCGCCACCTGCAGCGCAGCCATTTGGTGGACACTATTATAGAGATGCAAACGATGCATTCGTCGgcggccaccaccaccattaCAACAACGACGGCCACTATAGCCGGGCCAGTGGAGAATAAAGAATCTTTTAAGGACgagacgatgatgatgacgatgacgacaacGGCGGCTGCTGCAGGCAATGAGCTGGGAGGAAACCAGGATGATGAAACTGCAGCGCCACCAAAAGGGGAGCGTGCCGTGCCAGAGGAGGATGTGGATCCGGTGACATTGGACGCGGCCACTGCGGCGACGACAGCTGCCATAGCTGCTGCCATATCCTCTGCCTCCGTATCGCCCAGCGTCACAACAGCATTGGCACCTTCCGCATCCAATCTGTatcccacgcccacgcccttTGATTTCGACTATGACCTAATGGCCAACGATGCGCAGCGATCCCAGGTCTCGACACCCACCTCCCATCCCCAGCTGGGATCGCCCGGCAGCGGTCTGCTCAATGGCAGCGACAAGCTACTGACCACCGCCGCCATGGGGCCATACCCGACGAAGGGTCTGCGTTCCACCAGGCGGCAGGCGCATACTTCGATCTATATGTGCAAGCTGTGCAACAAGTCCTTCGACGAGCTGGGCAAGCTGGTCAAGCACGAGATGGAGTTGCACTCGAATACGGAACCCTCGCGATGGGGCTACCAGCACAAGTGTTCCATCTGCAGCACCAGCTACCGCACGCTAACGCTGCTAAAGTTTCACATGAAGCGGCACGTCAACCGGATATCGCAGTGCAAACTCTGCCCCAAGACCTTTGCCACCAACGCGGAGCTGGAGAGGCACATGAAGGTGAAACATTGCCGCGAAAAGTTGATCGGTCCTTGTGCGCTGAATGGCTGCAAAAAGATGTTCGCCTTCAAGCATCACATGGTGCGGCATCAGAACGCCTCTCATCTGAAATCCACGCATATCTGTGAAGTTTGCAACAAGGAGATGCTGACCATGGCGCACTTAAGATCCCACATGTTACTGCACAAGGGCATGGTGTCCTACAAGTGTCCCGAATGCGACCGCCTATATTTGCGGCGCGGAAGACTTTTAAGTCATCTAATGAATATTCACAAGAAACGCCTTACCGAAGATGAGAAGGCCATCCTCTTCGGCGAAGAAATCAAAGAAGAACCAAGCCCGCCGCAAAGCCCGAACGATCTAAAGGTGATGAGGAGGAGGGGGCGTCCCAGCCGCAAGATCTTGGAGGCGGCCGAATCGATGGTCAAGGAGGAGACGCAAACGGCAGCAGAACTTTCCAAATAG
Protein Sequence: MALNKRINPNPDALAGVAELNYKFACRCCLKVDAEFIKLESVSVARSLDPASEEDKISLLRCLLFCVRAENAAELPQYICVECSKSLQVAYYFLQNAVRAHEILCRKLCPGKVWNAEGRRFNGALSQRLQPSPSPKETATSGDRTRPLKSMRQECQVCGGIFHSRMELKLHLRQHTDGITYHCKMCNFTTLKQRQLLEHYRCDHAMTPSQAEEHVKASPLPISPIKEDEVKAVCTLEDMELLIPTVLTPDDYAQPPIDSEQLRDLDQQLAASMGDAVTGVDTLTSTLPPMDTAHNVSIGTEYLVLPDGSLQQVNGGGVVIEYIDDSKTQPPPPTPSNPPHINISLQNLLGNHDENEGMDIDVNELIVEDMMIHKPTISTAVPNPPKPKPVIGVSPNYKHKCSICPRMFSSVARLKSHQLTHSNLPKFFCDQCNFYSLRSVDLIEHYKTTHHRVDENGATSQDPAPGSEETGVYSCDMCLFETRTCSQLRVHYTEGHAIQPTEVQLRPSWTNNKATKMEQPLSGRQPEPADLPVAIKYPSIVADAQVPVQMQQEVPVQQQVPVQQQVPVQQQVQMQQQMQAQQLIQAQQQMQMQQQMQVQQQIQVQQQQQPVVVTTPTTLITHTNSNINVVVDTTPLFYASTVSSAVQQAVTVPVPEQTMPVPEQTMSVPVQVMPMLPPVATVVVESTNENNSHAFEVFPKIQPTNEQAKEPVPVDPIPSANTSNISMFGDMQDFIDNTDVAAICTIPADDMPVVDGDDIVIDNNNISLDFDAENLFEEFEEEDDTVGDDDEGDEEEEEEDEADNDDENDNNDAATDQNLLLTSDDDDVDDFDDEQSKHLQKPYCIYCNKKFTSQYKFENHMFVHRGLAPYRCELCTNLYNMKRLLIRHYKTVHKRMPTRDMVQAKGDKVLVTRTNIEKLYMDGVKSPMVMCAKCPFECEEDGEMRKHLNAHHGINDGLSIHANEVFIIRKLPFECPRCIRSFAAKATLTRHLQRSHLVDTIIEMQTMHSSAATTTITTTTATIAGPVENKESFKDETMMMTMTTTAAAAGNELGGNQDDETAAPPKGERAVPEEDVDPVTLDAATAATTAAIAAAISSASVSPSVTTALAPSASNLYPTPTPFDFDYDLMANDAQRSQVSTPTSHPQLGSPGSGLLNGSDKLLTTAAMGPYPTKGLRSTRRQAHTSIYMCKLCNKSFDELGKLVKHEMELHSNTEPSRWGYQHKCSICSTSYRTLTLLKFHMKRHVNRISQCKLCPKTFATNAELERHMKVKHCREKLIGPCALNGCKKMFAFKHHMVRHQNASHLKSTHICEVCNKEMLTMAHLRSHMLLHKGMVSYKCPECDRLYLRRGRLLSHLMNIHKKRLTEDEKAILFGEEIKEEPSPPQSPNDLKVMRRRGRPSRKILEAAESMVKEETQTAAELSK

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00524667;
90% Identity: iTF_00489645;
80% Identity: -