Basic Information

Insect: Drosophila leontia
Gene Symbol: -
Assembly: GCA_008042735.1
Location: VNKB01018486.1:24962-26927[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 8 6.1 5.2e+02 1.5 0.3 6 23 283 300 283 300 0.89

2 8 0.00033 0.028 14.9 4.0 1 23 306 328 306 328 0.99

3 8 0.027 2.3 8.9 4.8 1 23 337 359 337 359 0.95

4 8 4.6e-05 0.004 17.6 2.4 2 23 368 390 367 390 0.95

5 8 0.00055 0.047 14.2 0.0 3 23 398 418 397 418 0.96

6 8 0.00081 0.07 13.7 1.2 2 23 427 449 426 449 0.96

7 8 1.9e-07 1.6e-05 25.2 1.3 1 23 486 508 486 508 0.98

8 8 1.1e-05 0.00097 19.5 3.2 1 23 514 537 514 537 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	8	6.1	5.2e+02	1.5	0.3	6	23	283	300	283	300	0.89
2	8	0.00033	0.028	14.9	4.0	1	23	306	328	306	328	0.99
3	8	0.027	2.3	8.9	4.8	1	23	337	359	337	359	0.95
4	8	4.6e-05	0.004	17.6	2.4	2	23	368	390	367	390	0.95
5	8	0.00055	0.047	14.2	0.0	3	23	398	418	397	418	0.96
6	8	0.00081	0.07	13.7	1.2	2	23	427	449	426	449	0.96
7	8	1.9e-07	1.6e-05	25.2	1.3	1	23	486	508	486	508	0.98
8	8	1.1e-05	0.00097	19.5	3.2	1	23	514	537	514	537	0.98

Sequence Information

Coding Sequence: ATGCCGTGTTTTTTGTGCACTAAACATGTGGATGACAACGTGGGCAACATTGAGTTTCCCTCCGAGGAGGCTGACTCTATGGGCCTGCAGCCCATCATCGAAAAACATTTCTGGCTGCGGATCCATGACTCAGGCAGCGGCTACGTGTGCGGCGACTGCTGGGAGCAATTGCTGATCTTTCACAGCTTCTACCTCAGCGTAGAGCAGGCCCACATGGCGCTGGAGCAGACGACGCATGTGACGTTGCCTTCTCTGCCCACAGAAGTGGTGTCGGCGATCCTTGGTGGAGGGGAGGATGTGGTGAAGAACGAGGAAGGAGACAGCGTGGCGGCTGGCGTTAAGCGGCGACGAGGACGTCCCCGTAAAACGGAGGCAAAGGATGTGAGCGAGGAGCTCAAGACCGTGTTGGAGCAGATCAACCTGAATGAGATCAAAATTGAGTATCCTGAGGCGGATCTGACTATAGCCGATGTTCTGGAAGACCAGGAGGAGCACGACTACATGCCCAGCGACTGCGGCAGCGAGGACGAGGCTGACGAAGAcatggaggaggcggaggaggaggaggaaaagccgaagccgaagccgCCCAAGGTCCAGCGTAAGGCTCGCGGTCGTCCCAGAGGACGTGGACGCGGCCGTGGCCGCGGACGGGGAAAAGTAAGCCTGCCTGAACGGCCAAAGCGAACCGGTGTGCCGAATATGGCAAAGTCAAGGGAGTTCAACGCGTACATTCGGGAGCACTATAAGGTCCACTGCCCCGTCTGCAGTTTGCCCATGGAGGGCTTTTCGGAGATGTTAGTGCATGTGCGAGGCGAGCACAAGCAGCGTGGCTACTCCACATGCTGCAACCGCAAGTTCTGGAAGCGGGGCGTCCTGGTCGACCATCTGCGCCGCCACCAGGATCCAGAACTCTTCAAGTGCCACATCTGCCATCGCGTAATGGGCCAGCGTCGCAGTCTGGAGCTGCACATGCGCATGCACGAGATCAAGGCAAACGGACGTCGCTACCAGTGCGAGCATTGCTCCAAAAGCTTTTACAGTGCGGTGGTATGCGAGCGCCACAAGCTGACGCACATTCCCCGGGATCAGTGGCTCGTCAAGTGCACGCACTGCGAGAAGACTTTTCCCACTCAATATACGATGAAGCAGCACGTGAAGCTGGTCCACTTGAATTTATATGCCAAGATCTGCGATGTGTGCGGTAAATCCATCCGCGGCAGGGAGGCTTTGGTCCGCCATATGGAGGAGCACACGGGCGCACCACAGGCAGCCATCAGCTGTCATCTTTGTGACTCAAAGCTGACCACCAAATATGGCCTGGCCCGGCATATAAAGATGATGCATACCGCCGAGAATCTCCAGCCGATGCAATGCGAGCATTGCCTCAAGATCTCGCCCAGCCTGCAGGCGCATCAGCACCACTTGAAGTACACCCACAATACGGCTCGCACTCACCAGTGCCCGATGTGCGAGAAGGCCTTCAAGCGACCCAACGAGCTGAAgGAGCACATGACCACCCATACCGGGGAAGTGCTGTACACCTGTCCCCACTGCCCGCAGACCTTCAACTCCAATGCCAATATGCATGCCCACCGAAAGAAGGTTCATCGCAAGGAATGGGAGGAGAATCGTCATAAGCGGGTTTACCAGCCGCGGAAAGCGGACACGATCATTGCCGTAAGCGTGCGCAAGACGACGGAGGCACGGCTCGTTGGAGAGGCAAAGGCTGCTACAGAGATAGCAGCACCTCCAGCCGTAAGCTCTGGAGCCGAGTGCTAG
Protein Sequence: MPCFLCTKHVDDNVGNIEFPSEEADSMGLQPIIEKHFWLRIHDSGSGYVCGDCWEQLLIFHSFYLSVEQAHMALEQTTHVTLPSLPTEVVSAILGGGEDVVKNEEGDSVAAGVKRRRGRPRKTEAKDVSEELKTVLEQINLNEIKIEYPEADLTIADVLEDQEEHDYMPSDCGSEDEADEDMEEAEEEEEKPKPKPPKVQRKARGRPRGRGRGRGRGRGKVSLPERPKRTGVPNMAKSREFNAYIREHYKVHCPVCSLPMEGFSEMLVHVRGEHKQRGYSTCCNRKFWKRGVLVDHLRRHQDPELFKCHICHRVMGQRRSLELHMRMHEIKANGRRYQCEHCSKSFYSAVVCERHKLTHIPRDQWLVKCTHCEKTFPTQYTMKQHVKLVHLNLYAKICDVCGKSIRGREALVRHMEEHTGAPQAAISCHLCDSKLTTKYGLARHIKMMHTAENLQPMQCEHCLKISPSLQAHQHHLKYTHNTARTHQCPMCEKAFKRPNELKEHMTTHTGEVLYTCPHCPQTFNSNANMHAHRKKVHRKEWEENRHKRVYQPRKADTIIAVSVRKTTEARLVGEAKAATEIAAPPAVSSGAEC

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00541314;
90% Identity: iTF_00527587;
80% Identity: -