Dleo002402.1
Basic Information
- Insect
- Drosophila leontia
- Gene Symbol
- Znf574
- Assembly
- GCA_008042735.1
- Location
- VNKB01018433.1:19101-21297[-]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 10 0.2 17 6.2 2.2 2 23 335 357 334 357 0.95 2 10 0.031 2.6 8.7 0.1 6 23 367 384 367 384 0.98 3 10 4.6e-06 0.0004 20.8 3.1 1 23 390 412 390 412 0.98 4 10 0.72 61 4.4 0.8 1 14 421 434 421 444 0.73 5 10 0.00045 0.039 14.5 2.6 1 23 452 475 452 475 0.97 6 10 0.13 11 6.7 0.4 3 23 483 504 481 504 0.92 7 10 0.42 36 5.2 0.2 2 23 516 538 515 538 0.93 8 10 0.0033 0.29 11.8 3.2 1 23 545 568 545 568 0.93 9 10 1.5e-06 0.00013 22.3 1.4 1 23 574 596 574 596 0.98 10 10 0.034 2.9 8.6 3.3 1 23 602 625 602 625 0.97
Sequence Information
- Coding Sequence
- ATGGATTCCTCTTCCTGCTGCTTACTCTGCATGTGCGAGTATCCGGCGATGATGGGCGACTACATAGACGTGCAGTCCGCCAGGGCGTTGCAACTGGATGTGGCCCGGATTGTCAACCAGCACTTCCCCTTCCAGATCTCCCAGGAGAGTCGCGAAAGGATCTGCGGACGCTGCTGGAAAACCGTGTCCGACTTTCACACACTGCACGAATTCGTGAGCCAGGCACAGAACTCTTTGCAAGAGACGAAGGTACTGCTAATGGAGGATGATCCGCTCACCCAAGGCACTTCCTCCTTTTTGGCTGAAGCCGCCGCCAAAGTGGCCACCAGTGAAGAGCAGCCTTTGCAGGAGGCGTCGGAACTTGGCGGACGCAACTTCTTTTACCCGGAGGTCAAAATAGAAGAGCACGAACTGGATCACTTGCCGAGAATAGAAATCCTGGAGAGCACGGCCAACTCACAGACCACGCCAGACCAGCTGGAAGCCCCGCCCAGACGCCTGAGGAAGCGCTTGAAGGCCGAGGAGGACTCCTTACCCGACCCTGAGGTAATAGAGGAGCCTGTTGAGCCCACGCCGCCCAAAAAGCGTCGTGGAAGGCCCCGCAAAGCTGACTCCGCCACGGCAATTCCCCCTCAGAAACCAAAAGAAGACATTGAACTCAATCTAAAGTCCGAAGAAGTCGACGAGTTTGCCGACGAGGACCCGGACTTCACCTGCAACCTGGACGACGGCCTGGTGCCCAGCGATAATTCATCTGAGGACGACAACTACGGAGGCAGTGGAGGAGGCTTCGACTCCGATTCGGACTTCGAGCTGGACAAAGAGGGGAAGCAGGAGTTCGCTGTGCTGCCCAAGCGaacggtggtgcgtccgaaaAAGTACAAGAAGCGCACGAAACCGGCGGAGCCGAAGGTGCGCATGTCCCGcgagctgctggagcagcgcaagaagcagcaggaggagtacGACACCATCATTGCCAAGTTCTTTACCAGCGTGCTGCCGTGTCCGCTCTGCAACCTGATGGTGCACAACTTCACGGAGATGCAGCGCCACCACCGACTGACTCACCAGGTGGATCCCGGTTACATGATGTGCTGCGGCCGCAAGTTTACGCAGCGCAAAGTGCTGGCCGAGCACGTGCAAGTGCACTGGAATCCGGATCACTTCAAGTGCAGCGTGTGCGAGAAGTCGTTCCAGAACTCGCGGCACCTGGAGTCGCACCAGCAGGTGCACCTGGATCCGGCCATCAAGCTAACCTTCAGCTGCGACCTGTGCTCGAAGACCTTCCTCAGCAAGACGGCCATTGACTATCACAAGCTGAACAAGCATGTGCCCAAGTCGGAGTTCAAGTTCACCTGTTCAGAGTGCAATAAGAAATTCCTTACCGAACGCAAGCTAAAGAACCACATGAGCTCCATGCACGACCCGGAGAGCACCATCATCTGCGACAAGTGCGGCAAGCAGATGCGCACAAAAATTATCCTAAAGAAGCACCAGGAGCTGATGCACTCGGACAAGCCGCGCCCGGAGCCAGAGCTGAAGCAATGCCAGATCTGCGGAGCCTGGCTGAAGGGCATGACGGGACTGAAGCAGCACATGAAGAGCATCCATGTGGAGAGCGTGGGCGAGCATCGTTGTCACATCTGCGCCAAGGTGTCGCCGAATGCCAGGGCCCTGAGGCGTCACATCTATCACAACCACGAGTGCGAGCGAAAGTTCAAGTGCACCATGTGCGAGAAGGCCTTCAAACGGCCGCAAGAACTGAAGGAACACACTTCCACGCACACGGGCGAGGTACTCTACACCTGTCCCAACTGCCCGATGACCTTCTTCTGCAGCGCCAACATGTACAAGCATCGCCAGCGGCTGCATCGCGCCCAATACGAGGCGGACAAAAACCAGCCGAAGCCACCGAATATCCTGAAGATTTCCCGCAACGCCTCCGCGCACACGAAAATCTCCAAGCAGGAGATGTAG
- Protein Sequence
- MDSSSCCLLCMCEYPAMMGDYIDVQSARALQLDVARIVNQHFPFQISQESRERICGRCWKTVSDFHTLHEFVSQAQNSLQETKVLLMEDDPLTQGTSSFLAEAAAKVATSEEQPLQEASELGGRNFFYPEVKIEEHELDHLPRIEILESTANSQTTPDQLEAPPRRLRKRLKAEEDSLPDPEVIEEPVEPTPPKKRRGRPRKADSATAIPPQKPKEDIELNLKSEEVDEFADEDPDFTCNLDDGLVPSDNSSEDDNYGGSGGGFDSDSDFELDKEGKQEFAVLPKRTVVRPKKYKKRTKPAEPKVRMSRELLEQRKKQQEEYDTIIAKFFTSVLPCPLCNLMVHNFTEMQRHHRLTHQVDPGYMMCCGRKFTQRKVLAEHVQVHWNPDHFKCSVCEKSFQNSRHLESHQQVHLDPAIKLTFSCDLCSKTFLSKTAIDYHKLNKHVPKSEFKFTCSECNKKFLTERKLKNHMSSMHDPESTIICDKCGKQMRTKIILKKHQELMHSDKPRPEPELKQCQICGAWLKGMTGLKQHMKSIHVESVGEHRCHICAKVSPNARALRRHIYHNHECERKFKCTMCEKAFKRPQELKEHTSTHTGEVLYTCPNCPMTFFCSANMYKHRQRLHRAQYEADKNQPKPPNILKISRNASAHTKISKQEM
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00494659;
- 90% Identity
- iTF_00491762;
- 80% Identity
- -