Basic Information

Insect: Drosophila leontia
Gene Symbol: -
Assembly: GCA_008042735.1
Location: VNKB01009745.1:20500-31470[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 7 0.13 11 6.8 1.9 1 23 675 697 675 697 0.96

2 7 1.4e-05 0.0012 19.3 1.1 1 23 703 725 703 725 0.98

3 7 2.1e-05 0.0018 18.7 0.2 1 23 731 753 731 753 0.98

4 7 2.7e-06 0.00024 21.5 1.4 1 23 759 781 759 781 0.98

5 7 0.0031 0.26 11.9 2.1 1 23 787 809 787 809 0.98

6 7 4e-06 0.00035 21.0 2.4 3 23 817 837 815 837 0.94

7 7 0.00043 0.037 14.6 3.3 1 23 843 866 843 866 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	7	0.13	11	6.8	1.9	1	23	675	697	675	697	0.96
2	7	1.4e-05	0.0012	19.3	1.1	1	23	703	725	703	725	0.98
3	7	2.1e-05	0.0018	18.7	0.2	1	23	731	753	731	753	0.98
4	7	2.7e-06	0.00024	21.5	1.4	1	23	759	781	759	781	0.98
5	7	0.0031	0.26	11.9	2.1	1	23	787	809	787	809	0.98
6	7	4e-06	0.00035	21.0	2.4	3	23	817	837	815	837	0.94
7	7	0.00043	0.037	14.6	3.3	1	23	843	866	843	866	0.98

Sequence Information

Coding Sequence: ATGATGCCGCTGCAGGAGTCAACGCAATCCCTGAGCTGGCAGCTGGAGGATTACGCGTATTTCCACAAGTGCGGGGAAATAACCGCCTCGCCAGACGTCCAGAGCTTCGGCTTCAACTGCGCCTTCTGTCCGGCCATTTGCCTGCAGTTTTCCGTGTTCATGGACCACGTCCGGGAGCAGCACACCCAGGAGGTGAGGCGGCGCTACGACGCCGCCACTGCCGCCGAGGAACGGGCCGAGCAGCAAACGCAGACGGATCTGGTGATCATGGAACTGGACTGCCCGGAGATATTCCCTCTGGAGAACAAGAAAGCGGGAGGCGGGAGCCCCTGGGAACCCATGGAGGCGGACTTGGACGTTCAGCTAATGAGCCTTCTTCCGCCGGCGACCCCCACCGCTCTGCATGTAACCACCACGGAAGCCGTGGCGCCAGAAATAGATTTGGTTTACGTCGTTGAAAATCCATTGCCACCCTCGCCGCCGCCATCGGCGGGCATTTCAACGGGCGACGAGCTGCAGGGCCTGCACCTGGATCCCTTCACCCTGCTGCACGACGTGGTTATGACTCCGCCCACTCACTTGCCTTTGAATCCGCTAGCAGAGGGAGTTGCTCCCCCGGCAATTACAACTCCTCCGCTGCCGCGTTATGAGACACGACGCGTGGCAATGCAGCGCAAGCTTCGTCTGGCTGAAAACGAGAATGCAAAAGAGGGCGaagaggaggcggaggcggaggagctgctgctgcaaataGAGGAACTAGAGATGGAGGAGACAGGGGAGGCAGAGCCAGAGGAGGATCCGATCGAGCAGCCGGAGAAGAATGTTCTGGAAATGACGCCGCCAGCCACACCACCCACACCCCTGTCGCCCACCTCGCCCACCAGCAGCATGGCAAGCAGTCTGGATTTCCAAACGAGAACCCGTCGCGAGCTGGAGCGCAATCGGGAGTTTGTTGGCTCTCTGCTGACGGAATATGAACGCATGGAGAAGCTGTGGAATCCCCGGCACCCGGACTACAAATACAATGCCAAGCGTAGCGTCTACGGAGAGCTAGCTGCTCCGCTGGAATGCCACTGCCATATGCGGCTCTCCGGTGCCGAAATCTTCGCCGTGCTCAAGGAGCTACGGGGTAGATATCGCCGGGAGTTGAGCAAACTGAATGCCCTCGGTGGCAAGTACAAGTCACGGCTGTGGTACTTTGACAGGATGCACTTCCTCAGGGGCGTCATTGAAAACAAGCGAGCGGAGAGGGAAGCCAAGATTTCCGGTGAAAGCACTGAGAGTGAAAAATCTTGCGAAACGGACGCCGAGTCCTGCAGCAAGTCGACCCTTTACCGCGAAGTTCTCAGCTTTATACTGGACGCCTTCAAGCGACTGGAGTGCCTGTGGAATCCGCAGCATTACGACTATGCCAGTTGCAGCAAGAAGGACCTATACCGGGAGATATCCGTTCAGCTGCAGGAGGAGCTCAGCTACGAGCTGAGCGGCGAGGAGTGCTACAAGGAGATCCAGAAGCTGAGGACGCGCTATCGCAAGGAGCTGCGTATGGTGATCAAGCACAAGGGTCTGTACCTGCCCAAGCTGTGGTGCTACGACGAGATGGAGTTCCTGCAGCCAATACTCCAAGAGCAGATCTTCAATAAGATCAGCAAGAAAGTCGGGGTGGTGGAGACCAATCAGAAGACCAAGTTTATCGATGCCAGCTCCATACAATTCGCCACCGTCGAGGATCAGCTGCAGTTCGTGGAAATCTACCGCAACTACTCGGCCCTGTGGGATGTGGACCATCCCGACTTTCGTTCGAATGCCTATCGCAGCCAGGCCCTGGGCCAAATGCTGGATGAGCTGAACACCACCTTTCATACATCCTATGCCGCCGAGCAGCTGGAGAAGACGCTCTTTGATCTGCGCAAAGATTTCTCGGCTCAGAAACGTAAAATACTCACCGCTGACTCTAGCGCCAGCATTCCCCTGCTGCACGCCAAGCTGTCCGAGTTCCTGGAGCAGAACCTGGGACCCTTTCGCTGCGATGTGTGCACGGAATTGGTCAAGACCTGTGATCAGTACAAGGTTCACCGTTCCGGCCACGACGGAACGCAGCCTTTTATATGCACGCTCTGCGGCAAGGGCTTCCAGATGCCGTGCAACCTGACCGTGCATATACGGCGGCATCGTCGGGATTTCCCCTATGCTTGCGAGCAGTGCGACAAGCGCTTTGCCACATCCACGGAGGTGGCCATTCACTTGCGTAGTCACACCGGAGAGCGACCCTACATATGCGACCTGTGCGGCAAGTCCTTCAAGACCTGGTCCTTCTTTGATATCCACCGGCGACGGCACCTCAACCAGTCGACATTCCACTGCCCGATCTGTGCTAAAGGATTCTACGAGAAGAATCGTTTCACCGATCACATGAACTCCCACTGGGCGATACGTAAGCACCTGTGCACGGTGTGCGGCAAGACCTTTACCACCTACGGCAACCTAAAGAAGCACACGGAGCTGCACCTGACTGTGAAGAAATACAAGTGCAGTGCCTGTCACAAGCGCTTTGCCCAGTTTGCCAGCCTGCGATGGCACAAGAAGCGGGAGCACGGCCCCGAGgggcaggaggaggacgagaAGTAG
Protein Sequence: MMPLQESTQSLSWQLEDYAYFHKCGEITASPDVQSFGFNCAFCPAICLQFSVFMDHVREQHTQEVRRRYDAATAAEERAEQQTQTDLVIMELDCPEIFPLENKKAGGGSPWEPMEADLDVQLMSLLPPATPTALHVTTTEAVAPEIDLVYVVENPLPPSPPPSAGISTGDELQGLHLDPFTLLHDVVMTPPTHLPLNPLAEGVAPPAITTPPLPRYETRRVAMQRKLRLAENENAKEGEEEAEAEELLLQIEELEMEETGEAEPEEDPIEQPEKNVLEMTPPATPPTPLSPTSPTSSMASSLDFQTRTRRELERNREFVGSLLTEYERMEKLWNPRHPDYKYNAKRSVYGELAAPLECHCHMRLSGAEIFAVLKELRGRYRRELSKLNALGGKYKSRLWYFDRMHFLRGVIENKRAEREAKISGESTESEKSCETDAESCSKSTLYREVLSFILDAFKRLECLWNPQHYDYASCSKKDLYREISVQLQEELSYELSGEECYKEIQKLRTRYRKELRMVIKHKGLYLPKLWCYDEMEFLQPILQEQIFNKISKKVGVVETNQKTKFIDASSIQFATVEDQLQFVEIYRNYSALWDVDHPDFRSNAYRSQALGQMLDELNTTFHTSYAAEQLEKTLFDLRKDFSAQKRKILTADSSASIPLLHAKLSEFLEQNLGPFRCDVCTELVKTCDQYKVHRSGHDGTQPFICTLCGKGFQMPCNLTVHIRRHRRDFPYACEQCDKRFATSTEVAIHLRSHTGERPYICDLCGKSFKTWSFFDIHRRRHLNQSTFHCPICAKGFYEKNRFTDHMNSHWAIRKHLCTVCGKTFTTYGNLKKHTELHLTVKKYKCSACHKRFAQFASLRWHKKREHGPEGQEEDEK

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00507806;
90% Identity: iTF_00488883;
80% Identity: -