Basic Information

Insect: Drosophila leontia
Gene Symbol: sna
Assembly: GCA_008042735.1
Location: VNKB01018063.1:1-11060[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 5 4.2e-05 0.0036 17.8 2.2 1 23 245 267 245 267 0.97

2 5 6.6e-06 0.00057 20.3 0.6 1 23 280 302 280 302 0.98

3 5 1.8e-08 1.6e-06 28.3 0.4 1 23 306 328 306 328 0.97

4 5 1.4e-09 1.2e-07 31.9 0.3 1 23 334 356 334 356 0.99

5 5 1.7e-05 0.0015 19.0 1.2 1 19 362 380 362 383 0.94

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	5	4.2e-05	0.0036	17.8	2.2	1	23	245	267	245	267	0.97
2	5	6.6e-06	0.00057	20.3	0.6	1	23	280	302	280	302	0.98
3	5	1.8e-08	1.6e-06	28.3	0.4	1	23	306	328	306	328	0.97
4	5	1.4e-09	1.2e-07	31.9	0.3	1	23	334	356	334	356	0.99
5	5	1.7e-05	0.0015	19.0	1.2	1	19	362	380	362	383	0.94

Sequence Information

Coding Sequence: ATGGCCGCCAACTACAAAAGCTGCCCGCTCAAGAAGCGCCCCATCGTCTTTGTGGAGGAGCGTCTGCCGCAAACGGAGGCCTTGGCCCTGACCAAGGACTCGCTGTTTGCCCAGGACCAGCCCCAGGATCTCTCGCTGAAGCGTGGCCGCGAGGAGGATTACcagcaggagccggagcccAAGCGCGACTATGTTTTGAATCTCTCCAAGACTCCCGAGAGGATTTCCGTCATCAACTCCAGCTGCCTGCTGTCGCCGCCCGTTGAGCCCAGCCAGGATTACCATCCCACAGACATCCACATGCGCGGACTGACAGCCGGTACCACGGGCTACACCACCAGTGTCCCAGTGGCCAATCCCTTCCAGTCCGCCTTCGTAATGGCCGCCGGCTGCAATCCGATCTCGGCTCTGTGGAGCAGCTATCAGCCCCATTTGGCCGCCTTTCCCTCGCCCGCCAGCTCCATGGCCTCGCCGCAGTCCGTGTACAGCTACCAGCAGATGACGCCGCCCTCGAGTCCGGGTTCCGATCTGGAGACAGGATCCGAGCCAGAGGATCTCTCCGTGCGCAACGACATTCCACTGCCGGCTCTGTTCCACCTCTTCGACGAGGCTAGGTCCACGAGCAGCGGTGCCAGCGTGAGCAGCTCCTCGGGTTACTCCTCCTACGTTCCGACCAACGCCGCCACCACCCCGGCCGGCAACCAGGCCAGCCTGGCGGCCAAGAACTATCGCTTCAAGTGCGAGGAATGCCAGAAGATGTACTCCACCTCGATGGGCCTGTCCAAGCACCGGCAGTTCCATTGCCCGGCGGCGGAGTGCAACCAGGAGAAAAAGACCCATTCCTGCGAGGAGTGCGGCAAGCTGTACACCACCATTGGAGCGTTGAAGATGCACATCCGCACCCACACGCTGCCCTGCAAGTGCCCCATCTGCGGCAAGGCCTTCTCCCGTCCGTGGCTGCTCCAGGGTCATATCCGCACCCACACCGGCGAGAAGCCCTTCCAGTGCCCGGACTGCCCGCGATCCTTTGCTGATCGCTCCAACCTGCGAGCCCATCAGCAGACGCACGTGGATGTGAAGAAGTATGCCTGCCAGGTGTGCCACAAGTCCTTCTCGAGGATGTCGCTCCTGAACAAGCACTCCAGCTCCAACTGCACCATCACCATTGCGTAA
Protein Sequence: MAANYKSCPLKKRPIVFVEERLPQTEALALTKDSLFAQDQPQDLSLKRGREEDYQQEPEPKRDYVLNLSKTPERISVINSSCLLSPPVEPSQDYHPTDIHMRGLTAGTTGYTTSVPVANPFQSAFVMAAGCNPISALWSSYQPHLAAFPSPASSMASPQSVYSYQQMTPPSSPGSDLETGSEPEDLSVRNDIPLPALFHLFDEARSTSSGASVSSSSGYSSYVPTNAATTPAGNQASLAAKNYRFKCEECQKMYSTSMGLSKHRQFHCPAAECNQEKKTHSCEECGKLYTTIGALKMHIRTHTLPCKCPICGKAFSRPWLLQGHIRTHTGEKPFQCPDCPRSFADRSNLRAHQQTHVDVKKYACQVCHKSFSRMSLLNKHSSSNCTITIA

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00602797;
90% Identity: iTF_00593998;
80% Identity: -